Kenneth J. Hillers. University of Oregon Dept. of Chemistry , Supervised General Chemistry labs. Gave lectures and graded labs.

Transcription

1 Kenneth J. Hillers Assistant Professor Biological Sciences Department California Polytechnic State University, San Luis Obispo Educational Preparation University of Oregon, Eugene, OR Ph.D. Department of Chemistry and Institute of Molecular Biology, May Advisor: Dr. Frank Stahl. Western Washington University, Bellingham, WA Bachelor of Science, Biochemistry, Magna Cum Laude, June Advisor: Dr. Gerry Prody. Previous Experience and Activities Research Stanford School of Medicine Dept. of Developmental Biology Postdoctoral fellow. Advisor: Dr. Anne Villeneuve Investigation of regulation of recombination during meiosis in the nematode Caenorhabditis elegans, using genetic, molecular biological, and cytological methods. University of Oregon Institute of Molecular Biology Graduate Student. Advisor: Dr. Frank Stahl Studied repair of DNA double-strand breaks (DSBs) during meiosis in the yeast S. cerevisiae using genetic and molecular biological methods. Western Washington University Dept. of Chemistry Undergraduate. Advisor: Dr. Gerry Prody Investigated the biology of Tobacco Ringspot virus (a plant RNA virus) using cell and molecular biological methods. Teaching Experience University of Oregon Dept. of Chemistry , Supervised General Chemistry labs. Gave lectures and graded labs. Western Washington University Dept. of Chemistry Supervised General Chemistry, Organic Chemistry, Biochemistry, and Analytical Chemistry lab classes. Awards and Honors American Cancer Society Postdoctoral Research Fellowship 1999 Stanford University School of Medicine Dean s Fellowship 1999 Sea Bong Chang Award for Outstanding Biochemistry Graduate 1990 National Science Foundation Undergraduate Research Fellowship 1989

2 Previous Experience and Activities, cont d. Presentations Chromosome-wide regulation of meiotic crossing over requires meiotic axis component HIM- 3. K.J. Hillers, K. Nabeshima, and A. Villeneuve. Plenary presentation, 14 th International C. elegans Meeting. Los Angeles, CA July Chromosome-wide regulation of meiotic crossing over. K.J. Hillers and A. Villeneuve. Plenary presentation, 13 th International C. elegans Meeting. Los Angeles, CA June Publications Nabeshima, K., A. M. Villeneuve, and K. J. Hillers, Chromosome-wide regulation of meiotic crossover formation in Caenorhabditis elegans requires properly assembled chromosome axes. Genetics 168: Hillers, K. J., and A. M. Villeneuve, Chromosome-wide control of meiotic crossing over in C. elegans. Current Biology 13: Villeneuve, A. M., and K. J. Hillers, Whence Meiosis? Cell 106: Stahl, F. W., and K. J. Hillers, Heteroduplex rejection in yeast? Genetics 154: Hillers, K. J., and F. W. Stahl, The conversion gradient at HIS4 of Saccharomyces cerevisiae. I. Heteroduplex rejection and restoration of Mendelian segregation. Genetics 153: Foss, H. M., K. J. Hillers, and F. W. Stahl, The conversion gradient at HIS4 of Saccharomyces cerevisiae. II. A role for mismatch repair directed by biased resolution of the recombinational intermediate. Genetics 153: Current Activities Teaching Related Activities Courses Taught BIO 151 lab Introduction to Biology 4 WTUs BIO161 lab Intro to Cellular and Molecular Biology 2 WTUs BIO 303 Survey of genetics 3 WTUs (AY ); 4 WTUs (AY2005 on) BIO351 Principles of Genetics 5 WTUs BIO 375 Molecular Biology Laboratory 4 WTUs (until Spring 08); 5 WTUs (Fall 08 onward) BIO476 Gene Expression Laboratory 4 WTUs 2

3 Student Research and Senior Projects Undergraduates: Completed Senior Projects Sandra Dreike Mallory Embree Hannah Johnson Evan Massi Micheal Drummond Eric Dodge Rupa Makadia Rianna Knowles Sunny Sojka Cassy Haire Elaine Morlock Jenny Sato Anna Naccarati Stacey Kopp Lauren Burns Jessica Behring Ongoing Undergraduate Research Grace Bazan Stephanie Skidanenko Sophie Basecke MS candidates Completed Degree Joel Estis Jon Henzel Ongoing Resarch Kate Karfilis Rianna Knowles Professional Development Activities Publications Publications: Hillers, K.J. Crossover interference. Current Biology 14: R Solicited review for a reputable journal, written while under Cal Poly employ Hillers, K.J. and Villeneuve, A.M. Analysis of Meiotic Recombination in C. elegans, in Meiosis, Volume 1, Molecular and Genetic Methods (ed. Keeney, S; Humana press), Methods in Molecular Biology 557: Solicited review Presentations External Presentations Poster Presentation, 2007 CSU Biotechnology Symposium presented by Anna Naccarati and Sunny Sojka Poster Presentation, 2008 CSU Biotechnology Symposium presented by Jon Henzel Poster Presentation, 2008 Gordon Research Conference on Meiosis presented by Jon Henzel; this is the preeminent conference in the field Oral Presentation, 2009 CSUPERB research coference presented by Jon Henzel, who was a candidate for the Eden award 3

4 Cal Poly Presentations Poster Presentation, 2007 COSAM Student Research Conference presented by Anna Naccarati and Sunny Sojka Poster Presentations, 2008 COSAM Student Research Conference posters were presented by Henzel, Haire, Behring/Kopp Poster presentations, 2009 COSAM Student Research Conference posters were presented by Embree/Massi, Dodge, Knowles, and Sato Oral Presentation, 2009 COSAM Student Research Conference presented by Jon Henzel Grants and Contracts External CSUPERB Faculty seed grant, $10, Dec PI = Hillers. Funds to support initial investigations into regulation of meiotic recombination in yeast. Funds provided summer salary support for Sandra Drieke (undergrad) and supplies for S. Drieke and Mike Drummond (undergrads). NIH AREA (R15) program, $210,000 June 2009 May yr grant to support development of proteomic approaches to study of gametogenesis in C, elegans; revision and resubmission Internal State Faculty Support Grant, $4, plus 4 WTU release Sept PI = Hillers. Support for initial development of a genetic screen designed to identify mutations affecting meiotic chromosome segregation in yeast. Funds used to purchase supplies; Release time used S07. Undergrads involved: Elizabeth Munding; Elaine Morlock; Mallory Embree. Grad Students involved: John Henzel. Cal Poly Extramural Funds Initiative (EFI) Grant, $12, March 2007 PI = Hillers. Support for development of proteomic approaches to study of gametogenesis in C, elegans. Funds used to purchase supplies, pay my summer salary, and provide summer salary to Anna Naccarati. Undergrads involved: Sunny Sojka; Anna Naccarati; Cassy Haire Cal Poly EFI Grant, 5 WTU release September 2007 PI = Hillers. Release time for preparation of NIH grant to support development of proteomic approaches to study of gametogenesis in C, elegans. Release time used Fall 07 Cal Poly EFI Grant, $ plus 5 WTU release September 2008 PI = Hillers. Release time for preparation of revised NIH grant to support development of proteomic approaches to study of gametogenesis in C, elegans. Funds used to purchase supplies and reagents. Release time used Fall 08 4

5 Grant Applications (unfunded) NSF CAREER award, $789,656 July 2005 Comprehensive 5-yr grant to support research into the regulation of meiotic crossover formation in budding yeast. NIH AREA program, $150,000 Sept yr grant to support research into the regulation of meiotic crossover formation in budding yeast. CSUPERB Faculty Seed Grant, $15,000 Oct Funds to support a pilot screen to identify genes involved in crossover regulation NIH AREA program, $150,000 Oct yr grant to support research into the regulation of meiotic crossover formation in budding yeast. CSUPERB Faculty Seed Grant, $15,000 Oct Funds to support development of a proteomic approach to identification of proteins involved in gametogenesis in the nematode Caenorhabditis elegans. CSUPERB Faculty seed grant, $15, Sept co-pis = Hillers and Yeung. Funds to support development of C. elegans as a model system for Vibrio parahaemolyticus pathogenesis; proposal developed and submitted in collaboration with Dr. Marie Yeung (Cal Poly Biological Sciences) NIH AREA (R15) program, $150,000 Oct yr grant to support development of proteomic approaches to study of gametogenesis in C, elegans. Other Professional Development Activities Conferences attended, 2008: Gordon Research Conference, Meiosis June 8-13, 2008 Attended, accompanied by Jon Henzel, who presented a poster. This is the preeminent conference in the field. 5

6 Service Activities Department Undergraduate Coordinating Committee AY Biology Curriculum Committee Spring 2005 Temporary appointment Coordinator; Biotechnology Minor Summer 2006 present Summer Advising July 2007 Coordinate/Lead vision discussion at departmental retreat September 2007 Member, Fiscal Committee September 2008 present Chair, Fiscal Committee September present College Graduate School Advisory Panel Spring 2005 Participated in a panel discussion / question & answer session designed to provide guidance to undergraduate students contemplating graduate school. COSAM Student Research Conference 2005, 2007, 2008, 2009 Helped coordinate and facilitated student oral presentations at the COSAM Student Research Conferences University Participant, Bok colloquium Summer 2007 GE area B/F committee member September present 6