Biotechnology Activities at the National Institutes of Health: Priorities and Trends. US-EU Task Force on Biotechnology Brussels, July, 2006

Transcription

1 Biotechnology Activities at the s of Health: Priorities and Trends US-EU Task Force on Biotechnology Brussels, July, 2006

2 s of Health Office of of the the Director on on Aging on on Alcohol Abuse and and Alcoholism of of Allergy and and Infectious Diseases of of Arthritis and and Musculoskeletal and and Skin Diseases National Cancer Institute of of Child Health and and Human Development ational Institute on on eafness and and Other Communication Disorders of of Dental and and Craniofacial Research of of Diabetes and and Digestive and and Kidney Diseases on on Drug Abuse of of Environmental Health Sciences National Eye Eye Institute of of General Medical Sciences National Heart, Lung, and and Blood Institute National Human Genome Research Institute of of Mental Health of of Neurological Disorders and and Stroke of of Nursing Research of of Biomedical Imaging and Bioengineering National Center for for Complementary and and Alternative Medicine John E. Fogarty International Center National Center for for Research Resources National Library of of Medicine National Center on on Minority Health and and Health Disparities Clinical Center Center for for Information Technology Center for for Scientific Review

3 Most Institutes and Centers support biotechnology* NIH Biotechnology Grants and Activities Number of projects Fiscal Year ource: NIH Computer Retrieval of Information on Scientific Projects database.

4 NIH Focal Point --- Office of Biotechnology Activities, Office of the NIH Director

5 OBA Chief Activities Monitors scientific progress in human genetics research in order to anticipate future developments, including ethical, legal, and social concerns, in basic and clinical research involving Recombinant DNA, Genetic Technologies, and Xenotransplantation; Manages the operation of, and provides analytical support to, the NIH Recombinant DNA Advisory Committee, the DHHS Secretary's Advisory Committee on Genetics, Health, and Society, and the DHHS Secretary's Advisory Committee on Xenotransplantation; Coordinates and provides liaison with Federal and non-federal national and international organizations concerned with Recombinant DNA, Human Gene Transfer, Genetic Technologies, and Xenotransplantation; Provides advice to the NIH Director, other Federal agencies, and State regulatory organizations concerning Recombinant DNA research, Human Gene Transfer, Genetic Technologies, and Xenotransplantation; Responds to requests for information on highly technical matters and matters of public policy related to Recombinant DNA, Human Gene Transfer, Genetic Technologies, and Xenotransplantation; Develops and implements NIH policies and procedures for the safe conduct of Recombinant DNA Activities, and Human Gene Transfer; Reviews and evaluates the composition of Institutional Biosafety Committees; and Develops registries of activities related to Recombinant DNA Research and Human Gene Transfer.

6 OBA role on National Science Advisory Board for Biosecurity Advises federal departments and agencies on ways to minimize the possibility that knowledge and technologies emanating from vitally important biological research will be used to threaten public health or national security

7 Grants Traditional Mechanisms of NIH Support Cooperative Agreements Small Business Opportunities (SBIR/STTR) Contracts CRADAs

8 New Models NIH Roadmap Challenge Grant/Partnership Programs Vaccine Production Contracts NIAID Vaccine Research Center Research Resources

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11 Biotechnology Research Selected Areas of NIH Activity Vaccine development Imaging Diagnostics Tissue Engineering Marine biotech Environmental exposures

12 Public Private Partnerships Genetic Association Information Network (GAIN) -- NIH, Affymetrix, Pfizer Genetic factors underlying common disease NIH Foundation partnerships

13 Potential new areas of US-EU collaboration Workshop: Tissue engineering/regenerative medicine NIBIB interest Workshop: Nanotechnology & workplace safety developing a research agenda NIBIB and OBA interest Workshop: Environmental research and natural disasters Workshop: US-EU Approaches on Biotech with China and India Develop common definition of biotechnology

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16 NIH Road Map National Technology Centers for Networks and Pathways Goal: Develop proteomics technologies directed at understanding biological networks and pathways directed toward quantitatively defining the dynamics of the complex system Feature: 5 Multi-disciplinary centers with a biological focus to ensure technology development is applied to a relevant biological problem.