AUTOIMMUNITY CATALOGUE

Transcription

1 AUTOIMMUNITY Autoimmune Rheumatic Disease Antiphospholipid Syndrome ANCA & Vasculitis Hashimoto Thyroiditis Celiac Disease Autoimmune Gastroenteritis Disease Inflammatory Bowel Disease Autoimmune Diabetes type 1 Hepatic Disease

2 EXPORT AUTOMATED OR MANUAL ASSAYS - ELISA Autoimmune Rheumatic Disease AREASof CENTRAL & SOUTH AMERICA C10F80380 ANA Screen 96 tests Kit for qualitative determination of ANA antibodies (SS-A, SS-B, RNP 70, RNP/Sm, Centromere B, Jo-1 and Scl 70) C10F81000 ANA Multiscreen 96 tests Kit for qualitative screening of ANA antibodies (dsdna, histone, SS-A/Ro, SS-B/La, Sm, Sm/ RNP,Scl-70, PM-Scl-100, Jo-1 and Centromere antigens) C10F80390 ANA Combi 96 tests Kit for qualitative determination of ANA antibodies RNP-70 (strip A), RNP/Sm (strip B), MP (strip C), SS-A (strip D), SS-B (strip E), Scl-70 (strip F), Centromere B (strip G), Jo-1 (strip H) C10F81420 Anti-alpha Fodrin IgG/IgA 96 tests Kit for quantitative determination of IgG and IgA autoantibodies against alpha-fodrin. 6 liquid calibrators, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL C10F80490 Anti-C1q 96 tests Kit for quantitative determination of autoantibodies against C1q. 6 liquid calibrators, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL C10F81330 Anti-CENPB 96 tests Centromere B. 5 liquid calibrators, ready to use. IgG: 0, 10, 30, 100 and 300 U/mL C10F81040 Anti-dsDNA 96 tests Kit for quantitative determination of IgG autoantibodies against double-stranded DNA (dsdna), 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81041 Anti-dsDNA IgA 96 tests Kit for quantitative determination of IgA autoantibodies against double-stranded DNA (dsdna), 6 liquid calibrators, ready to use. IgA: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81042 Anti-dsDNA IgM 96 tests Kit for quantitative determination of IgM autoantibodies against double-stranded DNA (dsdna), 6 liquid calibrators, ready to use. IgM: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81043 Anti-dsDNA Screen 96 tests Kit for quantitative determination of IgG, IgM and IgA autoantibodies against doublestranded DNA (dsdna), 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/ ml; IgM: 0, 12.5, 25, 50, 100 and 200 U/mL; IgA: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81900 Dnase Activity 96 tests Kit for quantitative determination of DNase activity, 6 calibrators at different DNase Activity Reduction (AR) %, ready to use. 5, 15, 35, 50, 75 and 100 %AR/mL C10F80070 Anti-Histone 96 tests Kit for quantitative determination of autoantibodies against histone (H1, H2A,H2B, H3, H4). 6 calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80130 Anti-Jo1 96 tests Kit for quantitative determination of autoantibodies against Jo1 antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80280 Anti-Nucleosome 96 tests Kit for quantitative determination of autoantibodies against nucleosome. 6 liquid calibrators, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80170 Anti-Ribosome P 96 tests Kit for quantitative determination of autoantibodies against ribosomal P proteins. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL. 1

3 C10F80110 Anti-RNP/Sm 96 tests Kit for quantitative determination of autoantibodies against RNP/Sm antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81320 Anti-RNP70 96 tests Kit for quantitative determination of autoantibodies against RNP70 antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL Assay has been calibrated using international reference control sera recognized by CDC, Atlanta USA. C10F80120 Anti-Scl70 96 tests Scl-70 antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80100 Anti-Sm 96 tests Sm antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81520 Anti-SSA tests Kit for quantitative determination of IgG autoantibodies against SS-A 52 protein. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81600 Anti-SSA tests Kit for quantitative determination of IgG autoantibodies against SS-A 60 antigen. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80080 Anti-SSA 96 tests Kit for quantitative determination of IgG autoantibodies against SS-A. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80090 Anti-SSB 96 tests Kit for quantitative determination of IgG autoantibodies against SS-B. 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F81050 Anti-ssDNA 96 tests Kit for quantitative determination, in human serum or plasma, of IgG autoantibodies against single-stranded DNA (ssdna), 6 liquid calibrators, ready to use. IgG: 0, 12.5, 25, 50, 100 and 200 U/mL C10F80440 ENA Profile 4 96 tests Kit for semi-quantitative detection of IgG autoantibodies against extractable nuclear antigens (ENA). 3 color-coded strips for each antigen, with 8 testss per strip, each coated with an individual specific target of highly purified antigens (SS-A, SS-B, Sm, RNP/Sm) C10F80460 ENA Profile 6 96 tests Kit for semi-quantitative detection of IgG autoantibodies against extractable nuclear antigens (ENA). 2 color-coded strips for each antigen, with 8 testss per strip, each coated with an individual specific target of highly purified antigens (SS-A, SS-B, Sm, RNP/Sm, Scl- 70 and Jo-1) C10F80140 ENA Combi 12 tests Kit for semi-quantitative detection of IgG autoantibodies against extractable nuclear antigens (ENA). 12 strips, with 8 testss per strip, each coated with specific target (SS-A, SS-B, Sm, RNP/Sm, Scl-70 and Jo-1) C10F80060 ENA Screen 96 tests Kit for qualitative screening of IgG autoantibodies against extractable nuclear antigens (ENA). 12 strips, with 8 testss per strip, each coated with a mixture of highly purified antigens (SS-A, SS-B, Sm, RNP/Sm, Scl 70 and Jo-1). C10F80220 Rheumatoid Factor IgG 96 tests Kit for quantitative determination, in human serum or plasma, of Rheumatoid Factor IgG. 5 liquid calibrators, ready to use. IgG: 0, 15, 50, 150 and 500 U/mL C10F80221 Rheumatoid Factor IgM 96 tests Kit for quantitative determination, in human serum or plasma, of Rheumatoid Factor IgM. 5 liquid calibrators, ready to use. IgM: 0, 15, 50, 150 and 500 U/mL C10F80222 Rheumatoid Factor IgA 96 tests Kit for quantitative determination, in human serum or plasma, of Rheumatoid Factor IgA. 5 liquid calibrators, ready to use. IgA: 0, 15, 50, 150 and 500 U/mL C10F80223 Rheumatoid Factor Screen 96 tests Kit for quantitative determination, in human serum or plasma, of Rheumatoid Factor IgG, IgM and IgA. 5 liquid calibrators, ready to use. IgG, IgM and IgA: 0, 15, 50, 150 e 500 U/mL C10F80480 Anti-MCV 96 testss Kit for quantitative determination, in human serum or plasma, of IgG autoantibodies against mutated citrullinated vimentin (MCV). 6 liquid calibrators, ready to use. Breakable Antiphospholipid Syndrome C10F80150 Anti-Cardiolipin IgG/IgM 96 tests Kit for quantitative determination of anti-cardiolipin IgG/IgM autoantibodies. 6 combined liquid calibrators with IgG and IgM anti-cardiolipin antibodies, ready to use. IgG: 0, 7.5, 15, 30, 60 and 120 GPL U/mL; IgM: 0, 5, 10, 20, 40 and 80 MPL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville and specific IgG material IRP 97/656. C10F80151 Anti-Cardiolipin IgA 96 tests Kit for quantitative determination of anti-cardiolipin IgA autoantibodies. 6 liquid calibrators with IgA anti-cardiolipin antibodies, ready to use. IgA: 0, 7.5, 15, 30, 60 and 120 APL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville and specific IgG material IRP 97/656. C10F80152 Anti-Cardiolipin Screen 96 tests Kit for quantitative determination of anti-cardiolipin (IgG, IgM and IgA) autoantibodies. 4 combined liquid calibrators with IgG, IgA and IgM anti-cardiolipin antibodies, ready to use. 1 Negative Control (3.3 U/mL), 1 Cut-Off Control (10 U/mL), 1 Positive Control (30 U/mL), 1 High Positive Control (90 U/mL). Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F80210 Anti-Beta 2-Glycoprotein I IgG/IgM 96 tests Kit for quantitative determination of anti-beta-2-glycoprotein I IgG/IgM autoantibodies. 6 combined liquid calibrators with IgG/IgM anti-beta-2-glycoprotein I antibodies, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgM: 0, 6.3, 12.5, 25, 50 and 100 U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville and specific IgG material IRP 97/656. C10F80211 Anti-Beta 2-Glycoprotein I IgA 96 tests Kit for quantitative determination of anti-beta-2-glycoprotein I IgA autoantibodies. 6 liquid calibrators with IgA anti- beta-2-glycoprotein I antibodies, ready to use. IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL; Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville and specific IgG material IRP 97/656. C10F80212 Anti-Beta 2-Glycoprotein I Screen 96 tests Kit for quantitative determination of anti-beta-2-glycoprotein I (IgG, IgM and IgA) autoantibodies. 4 combined liquid calibrators with IgG, IgA and IgM anti-beta-2- glycoprotein I antibodies, ready to use. 1 Negative Control (A, 3.3 U/mL), 1 Cut-Off Control (B, 10 U/mL), 1 Positive Control (C, 30 U/mL), 1 High Positive Control (D, 90 U/mL). Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F81430 Anti-Annexin V IgG/IgM 96 tests Kit for quantitative determination of anti-annexin V IgG/IgM autoantibodies. 6 combined liquid calibrators with IgG and IgM anti-annexin V antibodies, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgM: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80290 Phospholipid Screen IgG/IgM 96 tests Kit for quantitative determination of IgG/IgM autoantibodies against cardiolipin, phosphatidyl serine, phosphatidyl inositol, phosphatidic acid (cofactor: beta-2-gpi). 6 combined liquid calibrators with antiphospholipid IgG and IgM, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 GPL U/mL; IgM: 0,6.3, 12.5, 25, 50 and 100 MPL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F80360 Anti-Phosphatidyl Inositol IgG/IgM 96 tests Kit for quantitative determination, in human serum or plasma, of IgG/IgM autoantibodies against phosphatidyl inositol 6 combined liquid calibrators with antiphospholipid IgG and IgM, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 GPL U/mL; IgM: 0,6.3, 12.5, 25, 50 and 100 MPL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F80350 Anti-Phosphatidyl Serine IgG/IgM 96 tests Kit for quantitative determination, in human serum or plasma, of IgG/IgM autoantibodies against phosphatidyl serine. 6 combined liquid calibrators with antiphospholipid IgG and IgM, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 GPL U/mL; IgM: 0,6.3, 12.5, 25, 50 and 100 MPL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. 2 3

4 C10F80370 Anti-Phosphatidic Acid IgG/IgM 96 tests Kit for quantitative determination, in human serum or plasma, of IgG/IgM autoantibodies against phosphatidic acid. 6 combined liquid calibrators with antiphospholipid IgG and IgM, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 GPL U/mL; IgM: 0,6.3, 12.5, 25, 50 and 100 MPL U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F80410 Anti-Prothrombin IgG/IgM 96 tests Kit for quantitative determination, in human serum or plasma, of IgG/IgM autoantibodies against prothrombin. 6 combined liquid calibrators with anti- prothrombin IgG and IgM, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgM: 0,6.3, 12.5, 25, 50 and 100 U/mL. C10F80411 Anti-Prothrombin IgA 96 tests Kit for quantitative determination, in human serum or plasma, of IgA autoantibodies against prothrombin. 6 liquid calibrators with anti- prothrombin IgA, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80250 Anti-Cathepsin G 96 tests cathepsin G. 6 liquid calibrators with IgG anti-cathepsin G, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80260 Anti Lysozyme 96 tests Kit for quantitative determination, in human serum or plasma, of IgG autoantibodies against lysozyme. 6 liquid calibrators with IgG anti-lysozyme, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80270 Anti-Lactoferrin 96 tests Kit for quantitative determination, in human serum or plasma, of IgG autoantibodies against lactoferrin. 6 liquid calibrators with IgG anti- lactoferrin, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Hashimoto Thyroiditis C10F80412 Anti-Prothrombin Screen 96 tests Kit for quantitative determination, in human serum or plasma, of IgG, IgM and IgA autoantibodies against prothrombin. 6 combined liquid calibrators with anti- prothrombin IgG, IgM and IgA, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgM: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80550 Phospholipid Profile 12 tests Kit for quantitative simultaneous and separate determination of IgG/IgM autoantibodies against beta-2-glycoprotein I, cardiolipin, phosphatidyl serine, phosphatidyl inositol, phosphatidic. 6 combined liquid calibrators with IgG and IgM antiphospholipid antibodies, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgM: 0, 6.3, 12.5, 25, 50 and 100 U/mL Assay has been calibrated using international reference control sera recognized by E.N. Harris, Louisville. C10F80030 Anti TPO 96 tests Kit for quantitative determination of antibodies against thyroid peroxidase (TPO). 6 calibrators with IgG antibodies against TPO, ready to use. IgG: 0, 3, 10, 30, 100 and 300 IU/ ml Assay has been calibrated against WHO MRC 66/387 international reference anti-tpo control sera. C10F80020 Anti TG 96 tests Kit for quantitative determination of antibodies against thyroglobulin (TG). 6 calibrators with IgG antibodies against TG, ready to use. IgG: 0, 3, 10, 30, 100 and 300 IU/mL Assay has been calibrated against WHO 65/93 international reference anti-tg control sera. Breakable strips ANCA & Vasculitis C10F80180 Anti PR3 (c-anca) 96 tests Kit for quantitative determination of autoantibodies against proteinase 3 (PR3). 6 liquid calibrators with IgG anti-pr3 antibodies, ready to use. IgG: 0, 5, 10, 20, 40 and 100 U/mL C10F81180 Anti PR3 sensitive (canca) 96 tests Kit for quantitative determination of autoantibodies against proteinase 3 (PR3). 6 liquid calibrators with IgG anti-pr3 antibodies, ready to use. IgG: 0, 10, 20, 40, 80 and 200 U/mL C10F80190 Anti MPO (p-anca) 96 tests Kit for quantitative determination of autoantibodies against myeloperoxidase (MPO). 6 liquid calibrators with IgG anti-mpo, ready to use. IgG: 0, 5, 10, 20, 40 and 100 U/mL. C10F80500 Anti-GBM 96 tests Kit for quantitative determination of IgG autoantibodies against GBM (NC1 alfa-3 (IV) ( Goodpasture antigen ). 5 liquid calibrators with IgG anti-gbm, ready to use. IgG: 0, 20, 40, 80 and 200 U/mL. C10F80890 ANCA Screen 96 tests Kit for qualitative screening of IgG autoantibodies against PR3 and MPO. 1 Negative Control, 1 Cut-Off Control and 1 Positive Control anti-anca; liquid, ready to use. C10F80300 ANCA Combi 12 tests Kit for separate qualitative determination of ANCA autoantibodies (PR3, MPO, BPI, Elastase, cathepsin G, lactoferrin and lysozyme). 1 Negative Control, 1 Cut-Off Control and 1 Positive Control; liquid, ready to use. C10F80230 Anti-BPI 96 tests BPI. 6 liquid calibrators with IgG anti-bpi, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/ ml. C10F80240 Anti-Elastase 96 tests Elastase. 6 liquid calibrators with IgG anti-elastase, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80050 Thyroglobulin 96 tests Kit for quantitative determination of thyroglobulin (TG). 6 liquid calibrators, ready to use. Antibodies against thyroglobulin: 0, 3, 10, 30, 100 and 300 ng/ml Assay has been calibrated against Certified Reference Material (CRM) for human thyroglobulin by BCR, Brussels. Celiac Disease C10F80340 Anti Gliadin IgA 96 tests Kit for quantitative determination of IgA antibodies against gliadin. 6 liquid calibrators with IgA antibodies against gliadin, ready to use. IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Breakable strips C10F80341 Anti Gliadin IgG 96 tests Kit for quantitative determination of IgG antibodies against gliadin. 6 liquid calibrators with IgG antibodies against gliadin, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Breakable strips C10F80342 Anti Gliadin Screen 96 tests Kit for quantitative determination of IgG and IgA antibodies against gliadin. 6 liquid combined calibrators with IgG/IgA antibodies against gliadin, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80400 Anti Tissue Transglutaminase IgA 96 tests Kit for quantitative determination of IgA antibodies against tissue transglutaminase. 6 liquid calibrators with IgA antibodies anti-ttg, ready to use. IgA: 0, 5, 10, 25, 75 and 200 U/mL. C10F80401 Anti Tissue Transglutaminase IgG 96 tests Kit for quantitative determination of IgG antibodies against tissue transglutaminase. 6 liquid calibrators with IgG antibodies anti-ttg, ready to use. IgG: 0, 5, 10, 25, 75 and 200 U/ ml. C10F80402 Anti Tissue Transglutaminase Screen 96 tests Kit for quantitative determination of IgG and IgA antibodies against tissue transglutaminase. 6 liquid combined calibrators with IgG and IgA antibodies anti-ttg, ready to use. IgG: 0, 5, 10, 25, 75 and 200 U/mL IgG: 0, 5, 10, 25, 75 and 200 U/mL; IgA: 0, 5, 10, 25, 75 and 200 U/ ml. 4 5

5 C10F80510 Anti DGP IgA 96 tests Kit for quantitative determination of IgA antibodies against deamidated gliadin protein epitopes (DGP). 6 liquid calibrators with IgA antibodies anti-dgp, ready to use. IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80511 Anti DGP IgG 96 tests Kit for quantitative determination of IgG antibodies against deamidated gliadin protein epitopes (DGP). 6 liquid calibrators with IgG antibodies anti-dgp, ready to use. IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F80512 Anti DGP Screen 96 tests Kit for quantitative determination of IgG and IgA antibodies against tissue deamidated gliadin protein epitopes (DGP). 6 liquid combined calibrators with IgG and IgA antibodies anti-dgp, ready to use. IgA/IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL Autoimmune Gastroenteritis Disease C10F80310 Anti-Parietal Cell 96 tests Kit for quantitative determination of IgG autoantibodies against the H+/K+-ATPase of parietal cells. 6 liquid calibrators with IgG anti- parietal cells, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. C10F81470 Anti-Intrinsic Factor 96 tests Kit for quantitative determination, in human serum or plasma, of IgG autoantibodies against intrinsic factor. 6 liquid calibrators with IgG anti- intrinsic factor, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Inflammatory Bowel Disease C10F80450 ASCA IgG/IgA 96 tests Kit for quantitative determination of IgG and IgA antibodies against mannan from Saccharomyces cerevisiae (ASCA). 6 liquid combined calibrators with IgG and IgA anti- Saccharomyces cerevisiae antibodies, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL; IgA: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Autoimmune Diabetes type 1 C10F80200 Anti Insulin 96 tests Kit for quantitative determination of autoantibodies against animal (cow, pig) and human insulin. 6 liquid calibrators with IgG anti-insulin, ready to use. IgG: 0, 6.3, 12.5, 25, 50 and 100 U/mL. Hepatic Disease C10F80160 AMA M2 96 tests Kit for quantitative determination of various proteins of the outer and inner mitochondrial membrane. 6 liquid calibrators with IgG AMA M2, ready to use. IgG: 0, 12.5, 25, 50, 100 e 200 IU/mL Assay has been calibrated against WHO 67/183 international standard at 100 IU/mL. MANUAL ASSAYS - BLOT/DOT Autoimmune Rheumatic Diseases C10F50100 ANA Dot 8 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against Sm, Sm/RNP, SSA (Ro), SSB (La), Jo-1 (histidyl-t-rna synthetase), Scl-70 (DNA topoisomerase I), PM-Scl 100 and CENP-A/B (centromere A/B proteins) antigens C10F50110 ANA Dot tests Immunodot kit for detection in human sera of IgG autoantibodies against Sm, Sm/RNP, SSA (Ro), SSB (La), Jo-1 (histidyl-t-rna synthetase), Scl-70 (DNA topoisomerase I), PM-Scl 100, Ku, CENP-A/B (centromere A/B proteins) and PCNA antigens C10F50120 ANA Dot tests Immunodot kit for detection in human sera of IgG autoantibodies against Sm, RNP (68kD /A/C), Sm/RNP, SSA (Ro), SSB (La), Jo-1 (histidyl-t-rna synthetase), Scl-70 (DNA topoisomerase I), PM-Scl, Ku, CENP-A/B (centromere A + B proteins), PCNA and Ribosome P0 antigens C10F50121 ANA Screen Dot tests Immunodot kit for detection in human sera of IgG autoantibodies against Sm, RNP (68kD /A/C), Sm/RNP, SSA (Ro), SSB (La), Jo-1 (histidyll-t-rna synthetase), Scl-70 (DNA topoisomerase I), PM-Scl, Ku, CENP-A/B (centromere A + B proteins), PCNA and Mi-2 antigens C10F71080 ANA-9 ImmunoBlot 8 tests Immunoblot kit for semi-quantitative detection of IgG autoantibodies against extractable nuclear antigens (ENA) SS-A 52, SS-A 60, SS-B,RNP/Sm, Sm, Centromere B, Jo-1, Scl-70 e ribosomal P proteins C10F71180 Nucleo-9 ImmunoBlot 8 tests Immunoblot kit for semi-quantitative detection of IgG autoantibodies against nuclear antigens: dsdna, nucleosome, SS-A, SS-B, Sm,RNP/Sm, Scl-70, Jo-1 and centromere B C10F50190 Connectivitis Dot 8 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against Nucleosomes, Histones, Sm, Sm/RNP, SSA (Ro), SSB (La), Jo-1 (histidyl-t-rna synthetase) and Scl-70 antigens C10F50200 Connectivitis Dot tests Immunodot kit for detection in human sera of IgG autoantibodies against Nucleosome, dsdna, Histones, Sm, Sm/RNP, SSA/Ro60kD, TRIM21 (SSA/Ro52kD), SSB, Jo-1 and Scl-70 antigens C10F50210 Cytoplasm Dot 6 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against M2 (OGDC-E2, BCOADC-E2, PDC-E2), Jo-1 (histidyl-t-rna synthetase), PL-7 (threonyl-t-rna synthetase), PL-12 (Alanyl-t-RNA synthetase), SRP-54 (signal recognition particle, 54 kd subunit) and Ribosomal P (P0) antigens C10F50230 ENA Dot 6 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against Sm, Sm/RNP, SSA (Ro), SSB (La), Jo-1 and Scl-70 antigens C10F50310 Lupus Screen Dot 4 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against Nucleosome, Histones, Sm and Ribosomal P0 Protein antigens C10F50350 Anti-Nucleosome Dot 1 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against nucleosomes antigens C10F50360 Anti-ENA/Nucleosome Dot 7 24 tests Immunodot kit intended for the detection in human sera of IgG autoantibodies against nucleosomes antigens. Sm, Sm/RNP, SSA, SSB, Jo-1 e Scl-70 C10F50370 Anti-Nucleosome/Histone Dot 2 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against nucleosome and Histone antigens 6 7

6 C10F50380 Polymiositis/Scleroderma Dot 8 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against Jo-1, PL-7, PL-12, SRP-54, Mi-2, Ku, Pm-Scl, Scl-70 antigens C10F76080 Myositis-Plus ImmunoBlot 8 tests Kit for semi-quantitative detection of autoantibodies against AMA-M2, Jo-1, PM-Scl-100, PL 7, PL 12, Mi-2, Ku (p70/80), SRP and Rib-P Antiphospholipid Syndrome C10F50150 Anti-Cardiolipin IgG/Beta 2 Glicoprotein I IgG Dot 2 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against the Cardiolipin (Cardiolipin/b2-GPI complex) and b2-gpi (isolated protein) antigens ANCA & Vasculitis C10F78980 ANCA 3 ImmunoBlot 8 tests Kit for semi-quantitative detection of autoantibodies against PR3, MPO e GBM C10F50130 ANCA Dot 2 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against the Myeloperoxidase (MPO) and Proteinase 3 (PR3) antigens C10F50140 ANCA GBM Dot 3 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against the Myeloperoxidase (MPO), Proteinase 3 (PR3) and Glomerular Basement Membrane/Collagen IV-K3 antigens C10F50250 Anti-GBM Dot 1 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against GBM antigen (Goodpasture antigen: Glomerular Basement Membrane/Collagen IV-K3) C10F78980 ANCA 3 ImmunoBlot 8 test 8 tests Immunoblot kit for the rapid and easy detection of antineutrophil cytoplasmic antibodies (ANCA) against PR3 (Proteinase 3), MPO (Myeloperoxidase) and GBM (Glomerular Basement Membrane) C10F50300 Liver Dot 7 24 tests Immunodot kit intended for the detection in human sera of IgG autoantibodies against M2 (OGDC-E2, BCOADC-E2, PDC-E2), gp210 (Nuclear Membrane associated antigen), sp100 (Multiple Nuclear Dots associated antigen), LKM1 (P450 2D6 fusion tri-peptide), LC1 (Formiminotransferase Cyclodeaminase), SLA (Soluble Liver Antigen) and F-Actin antigens C10F50411 Liver Dot tests Immunodot kit for detection in human sera of IgG autoantibodies against M2/nPDC (native Pyruvate Dehydrogenase Complex), M2/OGDC-E2 (Oxoglutarate dehydrogenase complex E2 subunit), M2/BCOADC-E2 (branched chain 2-oxo acid dehydrogenase complex E2 subunit), M2/PDC-E2, gp210 (membrane-associated nuclear antigen), sp100 (antigen associated with multiple nuclear dot), LKM1 (P450 2D6 fusion tri-peptide), LC1 (Formiminotransferase Cyclodeaminase), SLA (Soluble Liver Antigen) and F-Actin antigens C10F50344 Anti-Mitochondrial Dot 4 24 tests Immunodot kit for detection in human sera of IgG/IgM autoantibodies against M2/nPDC (native Pyruvate Dehydrogenase Complex), M2/OGDC-E2 (Oxoglutarate dehydrogenase complex E2 subunit), M2/BCOADC-E2 (branched chain 2-oxo acid dehydrogenase complex E2 subunit) and M2/PDC-E2 antigens C10F50402 Anti-Mitochondrial M2 Dot 2 24 tests Immunodot kit for detection in human sera of IgG/IgM autoantibodies against M2/nPDC and M2 recombinant (E2 subunits of OGDC, BCOADC and PDC) antigens Auxiliary Reagents C10FWD400 Wash Buffer Dot (10x) 40 ml Autoimmune Gastroenteritis Disease C10F50160 ASCA IgG/IgA Dot 1 24 tests Immunodot kit for detection in human sera of IgG/IgA antibodies against Saccharomyces cerevisiae (mannan) antigen C10F50260 Anti-Intrinsic Factor Dot 1 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against the Intrinsic Factor (IF) C10F50270 Anti-Parietal Cell/Intrinsic Factor Dot 2 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against the Intrinsic Factor (IF) and Parietal Cell (PCA) antigens C10F74080 Gastro 5 ImmunoBlot 8 tests Immunoblot kit for semi-quantitative determination of autoantibodies against Intrinsic Factor, Parietal Cell, Tissue Transglutaminase, Saccharomyces cerevisiae (ASCA) and Gliadin in human serum or plasma C10F50284 Liver Dot 4 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against M2/nPDC (subunit E1, E2, E3 of the pyruvate dehydrogenase complex), LKM1(P450 2D6 fusion tripeptide), LC1(Formiminotransferase Cyclodeaminase), SLA (Soluble Liver Antigen) antigens C10F50290 Liver Dot 5 24 tests Immunodot kit for detection in human sera of IgG autoantibodies against M2 (OGDC-E2, BCOADC-E2, PDC-E2), LKM1 (P450 2D6, fusion tri-peptide), LC1 (Formiminotransferase Cyclodeaminase), SLA (Soluble Liver Antigen) and F-Actin antigens 8 9

7 technology for everyone innovative pipetting system up to 7 microplates up to 28 IFA slides LED photometer

8 INSTRUMENTATION SkyLAB 752 system CODE PRODUCT NAME QUANTITY C Skylab752 1 Fully automated immunoassay processor, for processing up to 7 ELISA microplates and up to 28 IFA slides within the same working session. Continuous loading capability for samples and reagents. Able to perform RT and heated incubation, also with shaking. Sample predilution available as tests Up to 6 wash buffers on board SkyLAB 752 optional parts CODE PRODUCT NAME QUANTITY C Shaker-incubator unit 1 SkyLAB 752 consumable list CODE PRODUCT NAME QUANTITY C Dilution cuvette 250x8 C µl tips 10x96 C µl tips 10x96 Availability may be subject to change without prior notice AXA Diagnostics, an Italian company belonging to Dasit Group, has started its business in Among its goals, the primary is facilitating the work of laboratory specialists by offering them a wide range of products, systems and services as an aid for the diagnosis of several diseases. Company takes advantage of the skills of its team, whose career initiated on laboratory benches, cooperating with physicians and biologists since the early days of clinical diagnostics. The completeness of the proposed product lines and services is the result of continuous cooperation with physicians and constant updating on diagnostic techniques evolution. ENQUIRES axa_export@dgroup.it SERVICE SUPPORT axa_service@dgroup.it APPLICATION SUPPORT axa_application@dgroup.it AXA Diagnostics commitment is to proceed in this direction with the aim of enriching its catalogue with new products by offering a more and more complete service to the laboratory. AXA Diagnostics S.r.l. has certified its own Management System for Quality to comply with the contents of ISO , for providing safe and effective medical devices that satisfy legislative and operational customer needs. AXA Diagnostics products are brought to market by direct sales force in Italy and by a network of distributors abroad. contacts the company 12

9 AXA Diagnostics S.r.l. Ph Fax