Empower resource Management for Analysis of Workflow and System Utilization. Workshop C2

Transcription

1 Empower resource Management for Analysis of Workflow and System Utilization. Workshop C2 Gilles Bassard / Ömer Yilmaz 2013 Waters Corporation 1

2 Empower Driven Services - A Suite of Services Empower Environment Instrument Service Compliance Asset Management Resource Management Report Waters LC and MS Agilent LC and GC Instrument Qualification Software Qualification Validation Asset Care Connections INSIGHT irequests Resource and Workflow Management Service Event Management Software Compliance Audit Empower Database Server Audit 2013 Waters Corporation 2

3 Throughput Challenges in Analytical Labs Today Standards and sample preparation Data acquisition and processing Data compilation and management Optimizing multiple labs, working on multiple projects, on multiple time lines and goals to decrease costs and maximize asset utilization is a challenge Waters Corporation 3

4 What are the Key Impacts on Your Business? Greater Efficiency Manage Capacity Drive Continuous Improvement Initiatives Optimize Resource Utilization Improve Workflow Comply with Regulatory Compliance Reduce Costs 2013 Waters Corporation 4

5 What is Your Laboratory Overall Usage Pattern? Significant Improvement 2013 Waters Corporation 5

6 What is Your Individual System Usage? From a high level, to a low level, by instrument or by time period How are the instruments really being used? System 4 used significantly less than other systems in the lab 2013 Waters Corporation 6

7 Can You Predict When to Schedule Maintenance? Set your PM schedule based on actual usage of each individual system and 2013 Waters Corporation 7

8 Have You Considered New Technology Adoption? By switching from traditional HPLC to UPLC technology potential time savings of two days for specific instrument method 2013 Waters Corporation 8

9 Manufactured Drug In-process Timeline Using Established Lab Technology DAYS RxN #1 (12 hours) HPLC In-Process Monitoring #1 (6 hours) Data Analysis & Sign-Off (1 hour) RxN #2 (8 hours) 6 hours per HPLC monitoring step Total of 24 hours per batch HPLC In-Process Monitoring #2 (6 hours) Data Analysis & Sign-Off (1 hour) RxN #3 (19 hours) HPLC In-Process Monitoring #3 (6 hours) Analysis & Sign-Off (1 hour) (7 hours) RxN #4 In-Process Monitoring #4 (6 hours) HPLC Release & Sign-Off (1 hour) 2013 Waters Corporation 9

10 Manufactured Drug In-process Timeline Using Latest Lab Technology DAYS RxN #1 (12 hours) In-Process Monitoring #1 (1 hr, 40 min) Data Analysis & Sign-Off (1 hour) 1 hour 40 minutes per UPLC monitoring step Total of < 7 hours per batch RxN #2 (8 hours) In-Process Monitoring #2 (1 hr, 40 min) Data Analysis & Sign-Off (1 hour) RxN #3 (19 hours) Bulk drug substance shipped to Formulation 35% faster In-Process Monitoring #3 (1 hr, 40 min) Data Analysis & Sign-Off (1 hour) RxN #4 Solvent usage reduced by 50% for this method (7 hours) In-Process Monitoring #4 (1 hr, 40 min) savings in purchasing & Data Analysis & Sign-Off (1 hour) disposal costs: $20,000/year 2013 Waters Corporation 10

11 Where are the Bottlenecks in the Laboratory Workflow? Number of Days to Sign-Off 34 vs 7 days 2013 Waters Corporation 11

12 What is Your Audit Trail Trying to Tell You? The Audit Trail gives a good indication of the usage of Empower overall, and can highlight a number of issues 2013 Waters Corporation 12

13 Do You Measure Processing Method Robustness? Examining the number of re-processes, and the % of manual processing gives an indication of method robustness Some methods show 100% manual processing 2013 Waters Corporation 13

14 How Many Messages are in Your Message Center? Analysis of the Message Center can uncover any underlying issues within the system 2013 Waters Corporation 14

15 Are User Comments Meeting Compliance Requirements? Examining the comments that users are entering for methods and method changes can assure compliance 2013 Waters Corporation 15

16 Do You Know the Number of Versions for Each method and Why? Examining a method summary listing number of versions could identify compliance concerns 2013 Waters Corporation 16

17 Do You Monitor Your Service Metrics? Response time: more than 3 days is there an issue? Repair duration: more than 3 days why? 2013 Waters Corporation 17

18 Consultation Services and Resource Management Reporting Consultation Process Waters Business Impact Consultant will work with you to: o Understand your business objectives and goals to determine how these affect your laboratories o Gain understanding of your processes within your Empower environment o Mine data and service information in a secure manner from your Empower database o Customize analytics and reporting Meet with your key team members and Waters personnel supporting your account o Deliver recommendations that provide meaningful business impact for your organization 2013 Waters Corporation 18

19 Resource Management Report Service Event Information End User Feedback 2013 Waters Corporation 19

20 Consultative to Professional Services Consultative Service Professional Services Optimize process flow Improve Methods Improve instrument utilization Manage Empower efficiently Recover $$ on old assets Manage budgets effectively Reduce user errors Free up lab space Harmonize qualification Customize Maintenance Monitor impact of changes 2013 Waters Corporation 20

21 Resource Management Report Executive Summary Business Analysis and Objectives Technical Analysis Service Analysis Summary of Recommendations 2013 Waters Corporation 21

22 Resource Management Report Technical Analysis Resource Utilization System / user usage patterns Detailed UPLC Analysis Workstation vs LACE vs Citrix Column Usage Laboratory Workflow Detailed workflow analysis Processing method complexity Manual integration 2013 Waters Corporation 22

23 Resource Management Report Technical Analysis Administration LACE reboots Specific Message Center analysis Project Audit trails Sample Set recovery Custom field usage Administrative overhead Compliance AQT usage sqt usage System Policies Project Audit trail investigations Security System Policies Logons 2013 Waters Corporation 23

24 Resource Management Report Service Analytics Service Analysis Time to service Instruments with multiple unscheduled service events Status of Performance Maintenance service events 2013 Waters Corporation 24

25 Empower Driven Services EDS 365v Waters Corporation 25

26 Empower Driven Services EDS 365 Giving EDS (Empower Driven Services) customers the ability to obtain and monitor metrics related to their Empower system. Metrics will be in addition to, and complementary to the delivered Resource Management Report. The delivery mechanism for initial release of EDS 365 is Business Intelligence style dashboards accessed by customers on site by installing an EDSIP image and collecting data on a scheduled basis Waters Corporation 26

27 EDS 365 System Usage by Date (1) Empower Environment 2013 Waters Corporation 27

28 EDS 365 System Usage by Date (2) Empower Environment 2013 Waters Corporation 28

29 EDS 365 System Usage Days used Empower Environment 2013 Waters Corporation 29

30 EDS 365 System Usage Days used (2) Empower Environment 2013 Waters Corporation 30

31 EDS 365 System % Usage Empower Environment 2013 Waters Corporation 31

32 EDS 365 System % Usage patterns Empower Environment 2013 Waters Corporation 32

33 EDS 365 Message Center summary (1) Empower Environment 2013 Waters Corporation 33

34 EDS 365 Message Center summary (2) Empower Environment 2013 Waters Corporation 34

35 EDS 365 Message Center summary (3) Empower Environment 2013 Waters Corporation 35

36 EDS 365 Message Center Details 2013 Waters Corporation 36

37 What are the Key Impacts on Your Business? Greater Efficiency Manage Capacity Drive Continuous Improvement Initiatives Optimize Resource Utilization Improve Workflow Comply with Regulatory Compliance Reduce Costs Monitor diverse aspects of the Empower Network and workflow to help focus on system utilization, training needs, method productivity and provide justifications for laboratory needs. Resource Management Report and EDS Waters Corporation 37

38 Questions 2013 Waters Corporation 39