FRACTIONLYNX APPLICATION MANAGER

Transcription

1 FRACTIONLYNX APPLICATION MANAGER Sales Offices: Do you need more from your purification system and software? AUSTRIA STREAMLINE THE PURIFICATION PROCESS WITH AUTOPURIFY Complete, intelligent automation of sample analysis, purification and fraction assessment is achievable AUSTRALIA BELGIUM AND LUXEMBOURG World-renowned service and support Easy submission of samples, review of data and location Waters Connections provides the solutions you need to maintain maximum uptime using FractionLynx Application Manager s AutoPurify capabilities. By automating the transition between BRAZIL across your Waters systems. these processes, AutoPurify provides a uniquely integrated solution to the overall analysis and purification CANADA X2205 process. The entire process can be automated, or can be easily divided into single or two-step processes. Analytical Instrumentation and Software Services include Total Assurance Plans CZECH REPUBLIC that extend and enhance the original warranty you receive when you buy a DENMARK Waters product. These plans minimize the level of insurance investment and Confidence in unattended system operation FINLAND deliver the value you need to avoid costly and time-consuming system downtime. Intelligent fraction management and assessment Sample analysis FRANCE AutoPurify evaluates the result of the analytical run solutions for your regulatory compliance challenges. You can use Waters in the purification process. Based upon the purity HONG KONG Compliance Services to effectively train and certify personnel in equipment of the sample, the software determines if and how HUNGARY and regulatory requirements for cgmp/glp compliance, significantly reducing it should be purified. The purification strategy is INDIA displayed, and chemists can view and amend the IRELAND proposed preparative methods as necessary. ITALY Analytical chromatogram showing the peak of interest eluting at 3.6 minutes. Sample purification JAPAN KOREA you designate operating costs. Connections University is the center of our Educational Services, providing Pure and simple Pure compounds. High recoveries. Uncomplicated processes. Waters Preparative Chromatography Systems, extensive HPLC and LC/MS training and education at your site, at our corporate including MassLynx Software with FractionLynx Application Manager, simplify your purification and isolation headquarters or at our local offices around the world. processes. Representatives of Waters Global Customer Assurance Organization, trained and FractionLynx Application Manager, developed by Waters with extensive collaboration with our customers, is a MEXICO certified in all Waters products and current in HPLC and LC/MS applications, unique software package that provides your laboratory with the capability and confidence to automate your THE NETHERLANDS are available in person, on the phone, via FAX or at to answer purification process. Whether you are using UV- or MS-based fraction collection, FractionLynx Software effortlessly questions and provide you with service, support and information. tracks samples and fractions, and presents information in an easy-to-understand format. NORWAY Once the preparative method is chosen (either by the Selective collection of sample fractions based on criteria Connections Compliance Services provide you with timely and cost-efficient GERMANY and uses this information to determine the next step of fractions PEOPLE S REPUBLIC OF CHINA software or the chemist), purification is performed POLAND PUERTO RICO RUSSIA/CIS SINGAPORE Preparative chromatogram showing the SPAIN purification and collection of the peak of SWEDEN interest eluting at 2.9 minutes. SWITZERLAND TAIWAN UK Fraction assessment US Following sample purification, a re-analysis of the collected fraction can be performed to confirm purity. WATERS CORPORATION 34 Maple St. Milford, MA U.S.A. T: F: TIC of the pure collected fraction. Waters, TargetLynx, MassLynx, AutoPurify, Connections, and ESCi are trademarks of Waters Corporation. All other trademarks are property of their respective owners Waters Corporation Printed in the U.S.A. June EN LL-UL Compound purification can be automated with Waters portfolio of Preparative Chromatography Systems using FractionLynx Application Manager in conjunction with MassLynx Software.

2 PURIFYING COMPOUNDS WITH EASE AND CONFIDENCE TRACK SAMPLES, FRACTIONS AND ASSOCIATED DATA SIMPLIFY SYSTEM SETUP Designed to accommodate a diverse range of purification applications, FractionLynx Application The FractionLynx Browser provides fast, easy access to results and data. Successful sample purification is quickly Collection mode editing Manager offers a versatile solution to chemists responsible for sample purification. determined with color-coded maps. Chemists can access sample or fraction data by simply pointing and clicking on the sample or fraction location. Compound detection options include: you manage plate integrity and mapping: Ultra-violet (UV) absorbance Photodiode array (PDA) Click on a tube location for Evaporative light scattering (ELS) sample information. Color-coded views indicate if the compound Mass spectrometry (MS) Several collection options are available to help Fraction trigger, location Interactive fraction plate map gives and volume, as well as a visual location of fractions. export and pooling strategy. was or was not found. Sequential collection allows you to define a start location for continuous gathering of fractions, one tube after another. Plate mapping, or one-for-one collection, collects the fractions for a sample into a single location, Analog signals simplifying the spatial relationship between the Fraction triggering can be as simple or as sample and fraction layout. complex as you would like: Reserved tubes feature offers you the ability to Time-based criteria or signal intensity allocate a specified number of fraction collection threshold and slope can be designated tubes for samples. as fraction triggers. Multiple detection signals can be used in combination (and/or/not logic) to trigger Mass-directed purification with fraction triggering using fraction collection for additional sample ESCi Multi-Mode Ionization is available using the fractionation specificity. FractionLynx Application Manager. Spectrum list pane, containing The collection mode editor allows you to select fraction collection mode. Advanced features in system setup Bar codes Bar code tracking is supported in entry for each FractionLynx. Fraction viability and pooling spectra in the information is determined automatically, and current sample. results are easily exported to the necessary liquid handler. Sample safeguards- FractionLynx minimizes potential sample loss by monitoring the number of sequential samples that do not trigger a fraction collection. After a designated number of non-collection events, you can terminate system operation until the reason for non- SAMPLE SECURITY FractionLynx offers advanced features such as error monitoring and bar code support. collection is determined. Nothing gets lost with our enhanced collection Optional open access capabilities and waste management capabilities. Primary, secondary and waste collection enable the acquisition of compounds that are of major Through the use of an optional open access Spectrum of the peak selected concern, of minor concern (but not waste) and Spectral information for in the spectrum list pane. of the waste itself, as required. the selected fraction tube. Chromatograms and extracted chromatograms for UV, PDA, MS, ELS or analog signals. Primary, secondary and waste collection offer a secure way to preserve sample content. interface with MassLynx Software and FractionLynx Application Manager, Waters Preparative Chromatography Systems can be operated in a walk-up, walk-away manner. The open access interface guides users through the sample submission process, with a clear indication of where to place samples. This simple, one page log-in screen allows users to choose from a variety of different methods, and input the mass or absorbance wavelength for compound collection. An optional open access interface allows your system to be run in a walk-up, walkaway manner.

3 PURIFYING COMPOUNDS WITH EASE AND CONFIDENCE TRACK SAMPLES, FRACTIONS AND ASSOCIATED DATA SIMPLIFY SYSTEM SETUP Designed to accommodate a diverse range of purification applications, FractionLynx Application The FractionLynx Browser provides fast, easy access to results and data. Successful sample purification is quickly Collection mode editing Manager offers a versatile solution to chemists responsible for sample purification. determined with color-coded maps. Chemists can access sample or fraction data by simply pointing and clicking on the sample or fraction location. Compound detection options include: you manage plate integrity and mapping: Ultra-violet (UV) absorbance Photodiode array (PDA) Click on a tube location for Evaporative light scattering (ELS) sample information. Color-coded views indicate if the compound Mass spectrometry (MS) Several collection options are available to help Fraction trigger, location Interactive fraction plate map gives and volume, as well as a visual location of fractions. export and pooling strategy. was or was not found. Sequential collection allows you to define a start location for continuous gathering of fractions, one tube after another. Plate mapping, or one-for-one collection, collects the fractions for a sample into a single location, Analog signals simplifying the spatial relationship between the Fraction triggering can be as simple or as sample and fraction layout. complex as you would like: Reserved tubes feature offers you the ability to Time-based criteria or signal intensity allocate a specified number of fraction collection threshold and slope can be designated tubes for samples. as fraction triggers. Multiple detection signals can be used in combination (and/or/not logic) to trigger Mass-directed purification with fraction triggering using fraction collection for additional sample ESCi Multi-Mode Ionization is available using the fractionation specificity. FractionLynx Application Manager. Spectrum list pane, containing The collection mode editor allows you to select fraction collection mode. Advanced features in system setup Bar codes Bar code tracking is supported in entry for each FractionLynx. Fraction viability and pooling spectra in the information is determined automatically, and current sample. results are easily exported to the necessary liquid handler. Sample safeguards- FractionLynx minimizes potential sample loss by monitoring the number of sequential samples that do not trigger a fraction collection. After a designated number of non-collection events, you can terminate system operation until the reason for non- SAMPLE SECURITY FractionLynx offers advanced features such as error monitoring and bar code support. collection is determined. Nothing gets lost with our enhanced collection Optional open access capabilities and waste management capabilities. Primary, secondary and waste collection enable the acquisition of compounds that are of major Through the use of an optional open access Spectrum of the peak selected concern, of minor concern (but not waste) and Spectral information for in the spectrum list pane. of the waste itself, as required. the selected fraction tube. Chromatograms and extracted chromatograms for UV, PDA, MS, ELS or analog signals. Primary, secondary and waste collection offer a secure way to preserve sample content. interface with MassLynx Software and FractionLynx Application Manager, Waters Preparative Chromatography Systems can be operated in a walk-up, walk-away manner. The open access interface guides users through the sample submission process, with a clear indication of where to place samples. This simple, one page log-in screen allows users to choose from a variety of different methods, and input the mass or absorbance wavelength for compound collection. An optional open access interface allows your system to be run in a walk-up, walkaway manner.

4 PURIFYING COMPOUNDS WITH EASE AND CONFIDENCE TRACK SAMPLES, FRACTIONS AND ASSOCIATED DATA SIMPLIFY SYSTEM SETUP Designed to accommodate a diverse range of purification applications, FractionLynx Application The FractionLynx Browser provides fast, easy access to results and data. Successful sample purification is quickly Collection mode editing Manager offers a versatile solution to chemists responsible for sample purification. determined with color-coded maps. Chemists can access sample or fraction data by simply pointing and clicking on the sample or fraction location. Compound detection options include: you manage plate integrity and mapping: Ultra-violet (UV) absorbance Photodiode array (PDA) Click on a tube location for Evaporative light scattering (ELS) sample information. Color-coded views indicate if the compound Mass spectrometry (MS) Several collection options are available to help Fraction trigger, location Interactive fraction plate map gives and volume, as well as a visual location of fractions. export and pooling strategy. was or was not found. Sequential collection allows you to define a start location for continuous gathering of fractions, one tube after another. Plate mapping, or one-for-one collection, collects the fractions for a sample into a single location, Analog signals simplifying the spatial relationship between the Fraction triggering can be as simple or as sample and fraction layout. complex as you would like: Reserved tubes feature offers you the ability to Time-based criteria or signal intensity allocate a specified number of fraction collection threshold and slope can be designated tubes for samples. as fraction triggers. Multiple detection signals can be used in combination (and/or/not logic) to trigger Mass-directed purification with fraction triggering using fraction collection for additional sample ESCi Multi-Mode Ionization is available using the fractionation specificity. FractionLynx Application Manager. Spectrum list pane, containing FractionLynx offers advanced features such as error monitoring and bar code support. Advanced features in system setup Bar codes Bar code tracking is supported in entry for each FractionLynx. Fraction viability and pooling spectra in the information is determined automatically, and current sample. results are easily exported to the necessary liquid handler. Sample safeguards- FractionLynx minimizes potential sample loss by monitoring the number of sequential samples that do not trigger a fraction collection. After a designated number of non-collection events, you can terminate system operation until the reason for non- SAMPLE SECURITY The collection mode editor allows you to select fraction collection mode. collection is determined. Nothing gets lost with our enhanced collection Optional open access capabilities and waste management capabilities. Primary, secondary and waste collection enable the acquisition of compounds that are of major Through the use of an optional open access Spectrum of the peak selected concern, of minor concern (but not waste) and Spectral information for in the spectrum list pane. of the waste itself, as required. the selected fraction tube. Chromatograms and extracted chromatograms for UV, PDA, MS, ELS or analog signals. Primary, secondary and waste collection offer a secure way to preserve sample content. interface with MassLynx Software and FractionLynx Application Manager, Waters Preparative Chromatography Systems can be operated in a walk-up, walk-away manner. The open access interface guides users through the sample submission process, with a clear indication of where to place samples. This simple, one page log-in screen allows users to choose from a variety of different methods, and input the mass or absorbance wavelength for compound collection. An optional open access interface allows your system to be run in a walk-up, walkaway manner.

5 FRACTIONLYNX APPLICATION MANAGER Sales Offices: Do you need more from your purification system and software? AUSTRIA STREAMLINE THE PURIFICATION PROCESS WITH AUTOPURIFY Complete, intelligent automation of sample analysis, purification and fraction assessment is achievable AUSTRALIA BELGIUM AND LUXEMBOURG World-renowned service and support Easy submission of samples, review of data and location Waters Connections provides the solutions you need to maintain maximum uptime using FractionLynx Application Manager s AutoPurify capabilities. By automating the transition between BRAZIL across your Waters systems. these processes, AutoPurify provides a uniquely integrated solution to the overall analysis and purification CANADA X2205 process. The entire process can be automated, or can be easily divided into single or two-step processes. Analytical Instrumentation and Software Services include Total Assurance Plans CZECH REPUBLIC that extend and enhance the original warranty you receive when you buy a DENMARK Waters product. These plans minimize the level of insurance investment and Confidence in unattended system operation FINLAND deliver the value you need to avoid costly and time-consuming system downtime. Intelligent fraction management and assessment Sample analysis FRANCE AutoPurify evaluates the result of the analytical run solutions for your regulatory compliance challenges. You can use Waters in the purification process. Based upon the purity HONG KONG Compliance Services to effectively train and certify personnel in equipment of the sample, the software determines if and how HUNGARY and regulatory requirements for cgmp/glp compliance, significantly reducing it should be purified. The purification strategy is INDIA displayed, and chemists can view and amend the IRELAND proposed preparative methods as necessary. ITALY Analytical chromatogram showing the peak of interest eluting at 3.6 minutes. Sample purification JAPAN KOREA you designate operating costs. Connections University is the center of our Educational Services, providing Pure and simple Pure compounds. High recoveries. Uncomplicated processes. Waters Preparative Chromatography Systems, extensive HPLC and LC/MS training and education at your site, at our corporate including MassLynx Software with FractionLynx Application Manager, simplify your purification and isolation headquarters or at our local offices around the world. processes. Representatives of Waters Global Customer Assurance Organization, trained and FractionLynx Application Manager, developed by Waters with extensive collaboration with our customers, is a MEXICO certified in all Waters products and current in HPLC and LC/MS applications, unique software package that provides your laboratory with the capability and confidence to automate your THE NETHERLANDS are available in person, on the phone, via FAX or at to answer purification process. Whether you are using UV- or MS-based fraction collection, FractionLynx Software effortlessly questions and provide you with service, support and information. tracks samples and fractions, and presents information in an easy-to-understand format. NORWAY Once the preparative method is chosen (either by the Selective collection of sample fractions based on criteria Connections Compliance Services provide you with timely and cost-efficient GERMANY and uses this information to determine the next step of fractions PEOPLE S REPUBLIC OF CHINA software or the chemist), purification is performed POLAND PUERTO RICO RUSSIA/CIS SINGAPORE Preparative chromatogram showing the SPAIN purification and collection of the peak of SWEDEN interest eluting at 2.9 minutes. SWITZERLAND TAIWAN UK Fraction assessment US Following sample purification, a re-analysis of the collected fraction can be performed to confirm purity. WATERS CORPORATION 34 Maple St. Milford, MA U.S.A. T: F: TIC of the pure collected fraction. Waters, TargetLynx, MassLynx, AutoPurify, Connections, and ESCi are trademarks of Waters Corporation. All other trademarks are property of their respective owners Waters Corporation Printed in the U.S.A. June EN LL-UL Compound purification can be automated with Waters portfolio of Preparative Chromatography Systems using FractionLynx Application Manager in conjunction with MassLynx Software.

6 FRACTIONLYNX APPLICATION MANAGER Sales Offices: Do you need more from your purification system and software? AUSTRIA STREAMLINE THE PURIFICATION PROCESS WITH AUTOPURIFY Complete, intelligent automation of sample analysis, purification and fraction assessment is achievable AUSTRALIA BELGIUM AND LUXEMBOURG World-renowned service and support Easy submission of samples, review of data and location Waters Connections provides the solutions you need to maintain maximum uptime using FractionLynx Application Manager s AutoPurify capabilities. By automating the transition between BRAZIL across your Waters systems. these processes, AutoPurify provides a uniquely integrated solution to the overall analysis and purification CANADA X2205 process. The entire process can be automated, or can be easily divided into single or two-step processes. Analytical Instrumentation and Software Services include Total Assurance Plans CZECH REPUBLIC that extend and enhance the original warranty you receive when you buy a DENMARK Waters product. These plans minimize the level of insurance investment and Confidence in unattended system operation FINLAND deliver the value you need to avoid costly and time-consuming system downtime. Intelligent fraction management and assessment Sample analysis FRANCE AutoPurify evaluates the result of the analytical run solutions for your regulatory compliance challenges. You can use Waters in the purification process. Based upon the purity HONG KONG Compliance Services to effectively train and certify personnel in equipment of the sample, the software determines if and how HUNGARY and regulatory requirements for cgmp/glp compliance, significantly reducing it should be purified. The purification strategy is INDIA displayed, and chemists can view and amend the IRELAND proposed preparative methods as necessary. ITALY Analytical chromatogram showing the peak of interest eluting at 3.6 minutes. Sample purification JAPAN KOREA you designate operating costs. Connections University is the center of our Educational Services, providing Pure and simple Pure compounds. High recoveries. Uncomplicated processes. Waters Preparative Chromatography Systems, extensive HPLC and LC/MS training and education at your site, at our corporate including MassLynx Software with FractionLynx Application Manager, simplify your purification and isolation headquarters or at our local offices around the world. processes. Representatives of Waters Global Customer Assurance Organization, trained and FractionLynx Application Manager, developed by Waters with extensive collaboration with our customers, is a MEXICO certified in all Waters products and current in HPLC and LC/MS applications, unique software package that provides your laboratory with the capability and confidence to automate your THE NETHERLANDS are available in person, on the phone, via FAX or at to answer purification process. Whether you are using UV- or MS-based fraction collection, FractionLynx Software effortlessly questions and provide you with service, support and information. tracks samples and fractions, and presents information in an easy-to-understand format. NORWAY Once the preparative method is chosen (either by the Selective collection of sample fractions based on criteria Connections Compliance Services provide you with timely and cost-efficient GERMANY and uses this information to determine the next step of fractions PEOPLE S REPUBLIC OF CHINA software or the chemist), purification is performed POLAND PUERTO RICO RUSSIA/CIS SINGAPORE Preparative chromatogram showing the SPAIN purification and collection of the peak of SWEDEN interest eluting at 2.9 minutes. SWITZERLAND TAIWAN UK Fraction assessment US Following sample purification, a re-analysis of the collected fraction can be performed to confirm purity. WATERS CORPORATION 34 Maple St. Milford, MA U.S.A. T: F: TIC of the pure collected fraction. Waters, TargetLynx, MassLynx, AutoPurify, Connections, and ESCi are trademarks of Waters Corporation. All other trademarks are property of their respective owners Waters Corporation Printed in the U.S.A. June EN LL-UL Compound purification can be automated with Waters portfolio of Preparative Chromatography Systems using FractionLynx Application Manager in conjunction with MassLynx Software.