SEMANTIC DATA PLATFORM FOR HEALTHCARE. Dr. Philipp Daumke

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1 SEMANTIC DATA PLATFORM FOR HEALTHCARE Dr. Philipp Daumke

2 ABOUT AVERBIS Founded: 2007 Location: Team: Focus: Current Sectors: Freiburg, Germany Domain & IT-Experts Leverage structured & unstructured information Health, Pharma, Automotive, Publishers & Libraries

3 GENERAL GOALS The aim of SEMCARE (FP7, 2y, 1,5M) is to build a semantic data platform to support patient cohorting across large amounts of (un)structured patient data for primary and secondary use cases Scientific Coordinator, Language Technology Provider, Commercial Exploitation Leading Clinical Partner & Content Provider, Usability & Evaluation Language Technologies for Dutch, Terminology, Clinical Content Provider Terminology/Ontology Expert, Language Technologies for German, Clinical Content Provider Project Manager, Commercial Exploitation, Communication Planning

4 GENERAL GOALS The aim of SEMCARE is to build a semantic data platform to support patient cohorting across large amounts of (un)structured patient data for primary and secondary use cases Identify cohorts based on patientlevel criteria Anonymization of unstructured data for research purposes Gain insights in structured and unstructured data Easy and powerful interfaces for experts and novices Integration of heterogeneous data in various input formats Open infrastructure, easy 3rd party integration (e.g. transmart)

5 MAIN COMPONENTS The aim of SEMCARE is to build a semantic data platform to support patient cohorting across large amounts of (un)structured patient data for primary and secondary use cases Services Terminology Management Text Mining Search & Analytics 3rd party applications ETL, Data Integration Data Storage Data Privacy, Anonymization I2B2, transmart EHR4CR

6 MAIN COMPONENTS The aim of SEMCARE is to build a semantic data platform to support patient cohorting across large amounts of (un)structured patient data for primary and secondary use cases Services Terminology Management Text Mining Search & Analytics 3rd party applications ETL, Data Integration Data Storage Data Privacy I2B2, transmart EHR4CR

7 TERMINOLOGY MANAGEMENT

8 TERMINOLOGY MANAGEMENT HEALTHCARE Terminology Categories PHARMA Terminologies Categories ATC Drugs ChEBI Compounds FMA Anatomy ChEMBL Compounds HL7 Misc DrugBank Drugs ICD-10 Indications EntrezGene Genes ICD-O Onc Phenotype Ontology Phenotypes LOINC Lab Uberon M. Anatomy MedDRA Misc Uniprot Genes MeSH Misc OTHERS Terminologies Categories NCI-Thesaurus Misc Agrovoc Agriculture OPS Procedures Averbis Thesaurus Misc RadLex Radiology eclass Products RxNorm Drugs GeoNames Geo SNOMED CT Misc GND Misc UCUM Units ProfiClass Products UMLS Misc Quantities Units

9 TEXT MINING

10 OBSERVABLES, NUMBERS, UNITS

11 DEIDENTIFICATION

12 COHORT FINDER

13 TRANSMART / R

14 SERVICES The aim of SEMCARE is to build a semantic data platform to support patient cohorting across large amounts of (un)structured patient data for primary and secondary use cases Clinical Care Research Pharma Decision Support Predictive Analytics Feasibility Studies Coding & Billing Hypothesis Validation Patient Recruitment Quality Management Biomarker Validation Commercial Insights for Pharma

15 DECISION SUPPORT Show me all patients eligible for an implantable cardioverter-defibrillator (ICD)

16 DIAGNOSIS SUPPORT Show me all patients with typical Morbus Pompe symptoms, but without a Morbus Pompe diagnosis

17 COST & QUALITY CONTROLLING Show me all patients without secondary diagnosis Parkinson, but with mentionings of Parkinson or the drug Madopar in the EHR

18 COST & QUALITY CONTROLLING Show me all patients without secondary diagnosis Parkinson, but with mentionings of Parkinson or the drug Madopar in the EHR DRG G08B Complex reconstruction of the abdominal wall Fee: 3.390,68 DRG G08A Complex reconstruction of the abdominal wall with severe complications Fee: 5.667,61

19 DATA-DRIVEN PATIENT RECRUITMENT Show me all patients with diabetes mellitus, age between 18 and 70, and symptoms of depression, but without schizophrenia

20 For further questions, please contact: Dr. Philipp Daumke + 49 (0) philipp.daumke@averbis.com

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