Process and Architecture Overview IDMP Identification of Medicinal Products. Sven Eller, Life Sciences Solution Engagement Manager
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1 Process and Architecture Overview IDMP Identification of Medicinal Products Sven Eller, Life Sciences Solution Engagement Manager
2 Legal Disclaimer The information in this document is confidential and proprietary to SAP and may not be disclosed without the permission of SAP. This document is not subject to your license agreement or any other service or subscription agreement with SAP. SAP has no obligation to pursue any course of business outlined in this document or any related presentation, or to develop or release any functionality mentioned therein. This document, or any related presentation and SAP's strategy and possible future developments, products and or platforms directions and functionality are all subject to change and may be changed by SAP at any time for any reason without notice. The information on this document is not a commitment, promise or legal obligation to deliver any material, code or functionality. This document is provided without a warranty of any kind, either express or implied, including but not limited to, the implied warranties of merchantability, fitness for a particular purpose, or non-infringement. This document is for informational purposes and may not be incorporated into a contract. SAP assumes no responsibility for errors or omissions in this document, except if such damages were caused by SAP intentionally or grossly negligent. All forward-looking statements are subject to various risks and uncertainties that could cause actual results to differ materially from expectations. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of their dates, and they should not be relied upon in making purchasing decisions SAP SE or an SAP affiliate company. All rights reserved. 2
3 SAP s History Managing Global Regulations Operational Compliance Compliant Manufacturing (GMP) Good Lab Practices (GLP) HCP Spend (Sunshine Act) Serialization (GTIN/GLN) Regulatory In-take Global Trade Compliance Denied Parties Import/ Export Documentation Customs Duty Regulatory Policy Track & Trace GxP Submission of Drug Master Data Comply with Regulations Regulatory Submission ectd submission (through Partner: Lorenz Life Sciences) UDI and IDMP Environmental Compliance Waste Management Hazardous Material Occupational Health and Safety Emissions Management REACH Control Execution Financial Compliance SOX FCPA FASB, SEC (Dodd Frank) 2016 SAP SE or an SAP affiliate company. All rights reserved. 3
4 Agenda SAP s Development Approach IDMP Architecture Process 2016 SAP SE or an SAP affiliate company. All rights reserved. 4
5 IDMP Iterations Iteration 1: Already marketed drugs (See content in Article 57) Support life cycle management of MPIDs, PCIDs, PhPIDs Iteration 2: Investigational Medicinal Products Additional data elements and ISO Norm Iteration 3: Clinical Particulars Iteration 4: Batch Identifiers Remaining ISO norm content (ISO & ISO 20443) Iteration 5: Veterinary products 2015 SAP SE or an SAP affiliate company. All rights reserved. 5
6 Anticipated Scope & Timeline for IDMP/SPOR* Based on meeting minutes of IDMP taskforce meeting Feb 2016** Note: Timeline depends on publication date of EMA Guidelines July 2016 Q1/Q Q1/Q Q3/Q Expected Release of the EU Implementation Guideline Enforcement of Iteration 1 Law states: Implementation is July 2016 redefinition: Start of transition phase *SPOR = Substance, Products, Organisations, Referentials 1st submission: Product and Substance Iteration 1 ** Task Force MM only address Iteration 1, not the following Iteration 2. It is uncertain, when EMA will publish the timeline officially on their webpage 2015 SAP SE or an SAP affiliate company. All rights reserved. 6
7 Countries participating in IDMP standard definition FDA and EMA have decided to implement ISO IDMP regulations Source: Andrew Marr, EMA IDMP presentation 2016 SAP SE or an SAP affiliate company. All rights reserved. 7
8 Outlook Phased SAP Approach Step 1 Master Data Hub and Enterprise Data Model (Customer Co-Innovation has started) Step 2 Text Analysis for Regulatory Documents (Customers invited to PoC) Step 3 Message Creation and Submission (Timeline depending on EMA Implementation Guideline Availability) 2016 SAP SE or an SAP affiliate company. All rights reserved. 8
9 Listening to Our Customers 1. Option: IDMP Roundtable 2. Option: Co- Innovation 2016 SAP SE or an SAP affiliate company. All rights reserved. 9
10 Agenda SAP s Development Approach IDMP Architecture Process 2016 SAP SE or an SAP affiliate company. All rights reserved. 10
11 Architecture Details actions Workflow & Approvals Reporting SAP HANA for IDMP Enterprise-wide Master Data Hub Reg. Reg. Agency Agency Reg. Agency Non- SAP Systems* SAP Non-SAP** File Upload Consolidated Data Data Replication Consistency Rules IDMP Message structure & Message Content Direct via on-premise gateway (SAP or RIMS provider) or as future consideration via SAP Pharma Network in the Cloud Owners content *SAP ERP, EHS, MDG, ** CTMS, RIMS, GInAS, MDM, Controlled Vocabularies (Catalogs) Message structure definition (IDMP, UDI, ATTP, GS1, ) Staging and data cleansing Detection of inconsistencies Reporting on data content and quality Creating and approving submission content Built in extensibility concept for future requirements 2016 SAP SE or an SAP affiliate company. All rights reserved. 11
12 Agenda SAP s Development Approach IDMP Architecture Process 2016 SAP SE or an SAP affiliate company. All rights reserved. 12
13 IDMP Processes External Stakeholders Data from CMOs 5 Regulatory Agencies Regulatory Affairs UI 2 Integrate external information Data enrichment, address cleansing, duplicate check, Consistency check rules Regulatory Collaboration (Corporate / Local Reg Affairs) Adaptable workflow Auditable change process 8 Maintain Consolidate 4 Validate/ Cleanse 6 Inform Manage Change 9 Approve Submit Internal systems / Responsibility Matrix Local maintenance of IDMP relevant data in designated systems Information captured in Documents Work flow 7 Internal Stakeholders (R&D, Med.Affairs, PV, Manufacturing, Marketing, ) 2016 SAP SE or an SAP affiliate company. All rights reserved. 13
14 SAP Product Data Submission Management Medicinal Product View 2016 SAP SE or an SAP affiliate company. All rights reserved. 14
15 Any middleware (optional) Any middleware (optional) SAP Solution Offerings For Pharma Track And Trace ATTP: Manage Serialization Within Company / Pharma Network: Exchange Serialization Externally Government Any middleware 1 connection Pharma Network Cloud Open Q1 to Early Adopters ERP/ WM SAP Advanced Track and Trace for Pharmaceuticals On SAP HANA Cloud Platform 3PLs, CMOs wholesalers 100s of 1:1 connections available Early Adopter Model Any middleware (optional) Application interface framework (AIF restricted license included in SAP Advanced Track and Trace for Pharmaceuticals) Pack line/device AIF content shipped for regulatory reporting and CMO/wholesaler messaging 2016 SAP SE or an SAP affiliate company. All rights reserved. 15
16 Pharma Network Preview of Planned IDMP Functionality Key Collaboration Scenarios CMO Discussion 1: CMO Scenario Serial Number Request and Response CMO Commissioned IDs & Aggregations IDMP Information (Documents, WebUI Front-End, Messages) Pharma MAH Regulatory Reporting Messages 4: International Regulatory Reporting Scenario Authorities 3PL Commissioned IDs & Aggregations 2: 3PL Scenario Verification request & response for sellable returns Commissioned IDs & Aggregations according DSCSA CMO = Contract Manufacturing Organization 3PL = Third Party Logistic Provider MAH = Market Authorization Holder 3: US Supply Chain Scenario US Wholesaler Commissioned IDs & Aggregations according DSCSA 3: US Supply Chain Scenario US Hospitals Pharmacies SAP Advanced Track and Trace for Pharmaceuticals SAP IDMP Application Pharma Network (cloud) *simplified view 2016 SAP SE or an SAP affiliate company. All rights reserved. 16
17 Contact for IDMP, ATTP, Pharma Network: 2016 SAP SE or an SAP affiliate company. All rights reserved. 17
18 2016 SAP AG or an SAP affiliate company. All rights reserved. No part of this publication may be reproduced or transmitted in any form or for any purpose without the express permission of SAP AG or an SAP affiliate company. SAP and other SAP products and services mentioned herein as well as their respective logos are trademarks or registered trademarks of SAP AG (or an SAP affiliate company) in Germany and other countries. Please see for additional trademark information and notices. Some software products marketed by SAP AG and its distributors contain proprietary software components of other software vendors. National product specifications may vary. These materials are provided by SAP AG or an SAP affiliate company for informational purposes only, without representation or warranty of any kind, and SAP AG or its affiliated companies shall not be liable for errors or omissions with respect to the materials. The only warranties for SAP AG or SAP affiliate company products and services are those that are set forth in the express warranty statements accompanying such products and services, if any. Nothing herein should be construed as constituting an additional warranty. In particular, SAP AG or its affiliated companies have no obligation to pursue any course of business outlined in this document or any related presentation, or to develop or release any functionality mentioned therein. This document, or any related presentation, and SAP AG s or its affiliated companies strategy and possible future developments, products, and/or platform directions and functionality are all subject to change and may be changed by SAP AG or its affiliated companies at any time for any reason without notice. The information in this document is not a commitment, promise, or legal obligation to deliver any material, code, or functionality. All forward-looking statements are subject to various risks and uncertainties that could cause actual results to differ materially from expectations. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of their dates, and they should not be relied upon in making purchasing decisions SAP SE or an SAP affiliate company. All rights reserved. 18
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