Applied Biosystems Informatics Solutions for the Life Sciences. Jason McGlashan Oracle Life Science User Group Meeting

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1 Applied Biosystems Informatics Solutions for the Life Sciences Jason McGlashan Oracle Life Science User Group Meeting

2 Company Overview 20-year history of fueling life science innovation Instruments and reagents over 50,000 instrument systems installed in over 100 countries Informatics solutions 1000 installed sites global partner since 1986 LIMS ABI PRISM 3700 and Applied Biosystems 3730 DNA Analyzers and ABI PRISM 3100 and 3100-Avant Genetic Analyzers New TaqMan Gene Expression and Genotyping Assays Proteomics applications Celera Discovery System database

3 Enabling Integrated Science To better understand the complex interaction of biological systems, life scientists are developing revolutionary approaches to discovery that unite technology, informatics, and traditional laboratory research. In partnership with our customers, Applied Biosystems provides the innovative products, services, and knowledge resources to make this new, integrated science possible.

4 Applied Biosystems Informatics Software and Services Target Discovery Target Validation Pre-Clinical Clinical Research Manufacturing INFORMATICS SOLUTIONS From discovery to manufacturing LS*LIMS Software and SQL*LIMS Software Proven experience and services Enabling Integrated Science

5 LS*LIMS Software for Integrated Science Integrate and automate instruments Simplify workflow + management + Integrate data from different sources = Increased throughput and improved quality

6 Graphical Workflow Editor Mirror your lab operations and data flow Easy-to-use drag-and-drop interface Out-of-the-box instrument interfaces Pre-configured activities and workflows Novel workflow engine

7 Flexible, Extensible System Open, multi-tiered architecture Based on industry standards Software developer kit (SDK) and fully documented APIs TM

8 Software Core Components Instrument Communication Interface Sample Management Project Management Result Management Assay/Marker Management Workflow Management Applied Biosystems Software Architecture

9 Power of Applied Biosystems Software Architecture Simplifies Applied Biosystems instrument and application integration Provides common user experience across Applied Biosystems instruments and applications

10 Workflow Management Provide two interfaces for process-centric system Process Definition define end-to-end lab workflow Lab Console manage and execute daily lab work

11 LS*LIMS Software in Your Laboratory

12 Applied Biosystems Informatics Technology Summary SQL*LIMS v5 software Oracle9i Objects Web browsers LS*LIMS software Reports Oracle9i Database SQL*LIMS v4 software Microsoft Windows NT Intranet Oracle 8 Objects SQL*LIMS v3 software TCP / IP GUI Client / Server Reporting / events OpenVMS SQL*LIMS v2 2.2 software LAN / HOST / Character Terminals

13 Benefits of Using Oracle Scalability Compatibility Platform availability Security Global acceptance

14 Applera Corporation is committed to providing the world's leading technology and information for life scientists. Applera Corporation consists of the Applied Biosystems and Celera Genomics businesses. Applied Biosystems develops and markets instrument-based systems, reagents, software, and contract services to the life science industry and research community. Notice to Purchaser: License Disclaimer Purchase of this software product alone does not imply any license under any process, instrument or other apparatus, system, composition, reagent or kit rights under patent claims owned or otherwise controlled by Applera Corporation, either expressly or by estoppel. Applied Biosystems, GeneMapper, SQL*LIMS, and ABI PRISM are registered trademarks and AB(design), Applera, iscience, iscience (Design), LS*LIMS, and Celera Discovery System are trademarks of Applera Corporation or its subsidiaries in the US and/or certain other countries. All other trademarks are the properties of their respective owners. TaqMan is a registered trademarks of Roche Molecular Systems, Inc. Applied Biosystems develops and manufactures its products in accordance with ISO 9001:2000 systems quality requirements Applied Biosystems. All rights reserved.

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