Rhombix TM. Series Protein Crystallization Solutions. More insight and less mystery in crystallization. Analyze Detect Measure Control

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1 Rhombix TM Series Protein Crystallization Solutions More insight and less mystery in crystallization Analyze Detect Measure Control

2 THE RHOMBIX SYSTEM is unique in the way it integrates experimental details and automation settings in one centralized database, enabling advanced data mining and monitoring of experiments.

3 Rhombix Series Protein Crystallization Solutions Comprehensive Automation Solutions Proteins are notoriously difficult to grow and can be even harder to detect. The Rhombix Series of products from Thermo Electron Corporation offers comprehensive, proven solutions to both challenges. Our advanced image quality and state-of-the-art, multi-mode imaging make it easy to visualize even the most elusive crystal. Rhombix has captured the entire protein-crystallization process. We have worked with leading crystallographers to design a complete range of solutions from the ground up. They can provide every tool that you need and will deliver superior results. An investment in any Rhombix system is an investment in the future its modular design makes moving up to the next level of automation effortless. Improved speed and accuracy through automation are only the beginning of the Rhombix advantage. Our closed-loop software enables researchers to gather, analyze and use essential data more effectively, rapidly optimizing the crystallization process.

4 RHOMBIX UTILIZES THE BEST IN WORLD-CLASS OPTICAL TECHNOLOGIES TO ENHANCE THE PROCESS OF EXAMINING CRYSTAL IMAGES. VISION 750i VISION TABLESTORE FEATURES Advanced Image Quality and Clarity Rhombix utilizes the best in world-class optical technologies to enhance the process of examining crystal images. Our special camera-and-lens configuration, with true color detection and advanced software algorithms, provides the flexibility to perform a variety of operations to improve the quality of images. Autofocus Drop finding X-focus Rapid image capture Microscope mode Superior Multi-Mode Imaging The key to effectively detecting crystals lies in being able to draw on a choice of top-quality imaging modes. Our highly regarded lighting system ensures that if a crystal develops, you ll detect it. The system delivers true polarized conditions that take advantage of the birefringent property of crystals. Sophisticated Data Management The Rhombix system is unique in the way it integrates experimental details and automation settings in one centralized database, enabling advanced data mining and monitoring of experiments. Our exclusive Remote Data Sharing capability allows a researcher to design experiments and share the results within the laboratory or across the globe. Remote data sharing Platform-independent access through Microsoft Terminal Services Easy data entry and viewing through the Rhombix Software Suite Easy data retrieval through our patent-pending Visual Query Tool software and Reporting Tool plug-in Brightfield Darkfield True Polarized extinction and variable angle

5 OPUS VISION WORKSTATION PRODUCT OFFERING OPUS SYSTEM This fully automated and integrated protein-crystallization system is ideal for high-throughput crystallography, as well as systems shared by many users, such as structural centers and service providers. Robust liquid handling Flexible plate storage Advanced imaging components SCREEN SYSTEM Enables high-performance liquid handling for protein-crystallization plate preparation. It integrates best-in-class equipment for reliable preparation of screens and protein drops. Automates design and building of crystallization experiments Assembles crystallization plates VISION 750i AND 1250i SYSTEM Provides temperature-controlled or ambient highcapacity automated storage and imaging for crystal detection. It is a perfect solution for labs requiring high-capacity storage and/or full automation. 700 to 1300 plate capacity Images up to well plates per day Dynamic scheduling with sophisticated conflict resolution Compatible with SBS and Linbro plate types VISION TABLESTORE With its ambient storage and imaging for protein crystal detection, the TableStore provides the same features as our higher-capacity Vision systems. It is recommended for labs desiring high-quality, automated imaging. And its small footprint is ideal for labs with atmosphere-controlled environments. VISION WORKSTATION This stand-alone crystal-detection imager offers full database access. It is ideal for researchers who need high-quality imaging but not storage. Integrated database tools for storage and retrieval of images Supports SBS and Linbro; sitting drop, hanging drop and microbatch Upgrade path to automated systems SOFTWARE SUITE A comprehensive package of software tools for controlling the automation of products, as well as collecting and analyzing data. The software is specifically designed for protein crystallization and is written in the language of the crystallographer. Design experiments Configure and run experiments Analyze data Mine the data for experimental optimization

6 Thermo Services Thermo is committed to helping your laboratory achieve success. Our solutions ensure that your Thermo automation systems are optimized for accuracy, productivity and performance. We offer flexible solutions: Service agreements Preventative maintenance plans Software upgrades Software application support Technical support Integration services Relocation services Training Contact a Thermo representative to tailor the service solution that best meets your needs. Laboratory Equipment Division Laboratory Automation and Integration 5344 John Lucas Drive Burlington, ON L7L 6A6 Canada North America: sales.labautomation@thermo.com Europe: sales.labequip.uk@thermo.com Asia: China India Japan Hong Kong (including Asia Pacific) info.labequipment.cn@thermo.com Thermo Electron Corporation. All rights reserved. Thermo, Analyze, Detect, Measure, Control, Rhombix are the property of Thermo Electron Corporation. Microsoft is a registered trademark of Microsoft Corporation. Bro-LAI-Rhombix-11/05 Analyze Detect Measure Control