BIG DATA - UNLOCKING DATA FOR

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1 BIG DATA - UNLOCKING DATA FOR POPULATION HEALTH AND RESEARCH FIORA AU, TAREK SALEH, DOMINIC MORGAN

2 Hospital centric Patient centric Treatment Prevention Acute Primary Intuition Evidence based Healthcare Personalised medicine Better data, broken out of silos Population health is SHIFTING but still, the lingering need to work with legacy Page Orion Health group of companies

3 Transformation through better data Faster and easier through improved coordination and automation Better decisions through seeing the whole picture What What s next? Who When How s it going What might happen? Page Orion Health group of companies

4 Making data useful Also known as IDCR Consult CDR (6, 8) Clinical Portal Single View Open Platform ECR Concerto Hospital Workstation More! faster Storing quality data Who can see what? Data liquidity & insights More later Rhapsody Integration Engine Built for Flexibility & Scalability Data Engine Cleansing Enrichment Sequencing Mapping Data models Custom data spaces Privacy engine Consent Break the seal API Management Auditing Web & Mobile apps Open APIs Bulk extract Reporting Analytics Notifications Raw data store Replay Continuous Delivery Page Orion Health group of companies

5 ANALYTICS Analytics Coordinate Medicines Consult Engage Page Orion Health group of companies Amadeus

6 Data in action Open APIs for querying and integration with 3 rd party analytics Amadeus Analytics Engine for patient identification & stratification, and clinical quality measures The role of data in Clinical Research Page Orion Health group of companies

7 Open APIs Presentation API Management Security & Threat protection Analytics Traffic control Operations Secured access RESTful APIs Business logic Data Engine and Spaces Data integration Page Orion Health group of companies

8 Documentation & examples Self service Sandbox Now live. Go play! Page Orion Health group of companies

9 Example: FHIR Observation Get observations for the patient whose ID is 1234 subject.identifier=1234 of these types, HDL (LOINC code ) and LDL (LOINC code ) cholesterol &code= in the date range 2016 May 1 st to 2017 May 1 st &date=>= &date=<= in reverse chronological order &_sort:desc=date Page Orion Health group of companies

10 Example: Framingham Risk Score Charles Dodgson Age 77yrs Gender Male LDL 139 mg/dl HDL 56 mg/dl Get relevant observations and conditions for Charles Return them Smoker No General CVD 10yr risk (Framingham) 33% Based on: Age 77yrs Gender Male LDL 139 mg/dl HDL 56 mg/dl Write back calculated risk score Smoker No Page Orion Health group of companies Open source Framingham calculator

11 Example: Framingham Risk Score Charles Dodgson Age 77yrs Update smoker status to Yes Personal finance app Smoker Yes Previous Framingham score 33% (with what it was based on) New Framingham score 47% Based on: Age 77yrs Gender Male LDL 139 mg/dl HDL 56 mg/dl Write back updated risk score Smoker Yes Page Orion Health group of companies Open source Framingham calculator

12 AMADEUS ANALTYICS ENGINE TAREK SALEH

13 Orion Health Analytics Major Development Themes Quality & Compliance Reporting Managing Revenue and Cost Risk Stratification & Machine Learning Care Coordination Monitor and manage key performance metrics under value based contracts: Pay for Performance Shared Savings Bundled Payments Give practices and providers the tools required to identify and close care gaps. Tools to identify key contributors to costs: Readmissions Utilization PMPM Patient Risk Stratification HCC Risk Model John Hopkins ACG High Risk Discharge & Medical Adherence analysis Machine Learning & Predictive Analytics Proprietary Risk Algorithms Population exploration tools for care coordination staff Patient risk stratification tools High risk discharge and medication adherence analysis Page Orion Health group of companies

14 Amadeus Analytics Overview Amadeus Analytics 11 Financial Performance Ad-Hoc Reporting Benchmarking Clinical Performance Cost & Utilization Metrics Cohort Builder PHE Performance Reporting Bulk Download NCQA Certification Clinical Quality Measures 8 Patient Identification Risk Stratification PMPM Membership Chronic Disease Spend 3 rd Party Tools 6 7 HEDIS MSSP MACRA/ MIPS 9 10 HCC ACG Predictive Analytics (ML) Data Compliance 4 5 Utilization Performance Reporting Manual PWY Assignment Intelligent PWY Assignment 14 Future Current Page Orion Health group of companies Identify Gaps in Care Compliance Reporting Coordinate Integration Close Care Gaps

15 Precision Driven Health Empowering Data-Driven Precision Health Precision Driven Health Mission Precision Driven Health is a partnership across commercial, health providers and researchers, investing around $38m over seven years. Funding is from participating partners and the Ministry for Business, Innovation and Employment The Precision Driven Health Research Partnership is creating the capability to optimize the health of each individual and their whanau by combining and learning from all available data. This will improve health outcomes globally, increase health provider efficiency, and enable commercial success. Page Orion Health group of companies

16 Precision Driven Health Four research themes to enable future health Theme 1 New data sources Individuals Health Professionals Theme 4 Empower patients Health Coordinators Theme 2 Predictive modelling Individual Data Knowledge Base Genome Consumer Environmental Pharmacy Lab Community Clinical Payer Social Current facts & Practice Genome Annotations Theme 3 Precise & timely healthcare Device Interpretation Environment Interpretation Integrated Predictive models Integrated decision models

17 Current Projects Theme One: New Data Sources Theme Two: Predictive Modelling Theme Three: Precise and Timely Healthcare Theme Four: Empowering People Page Orion Health group of companies Data Review Quentin Thurier Research Repository Junjae Lee Vital Signs Monitoring and Decision Support System Hamid GholamHosseini Integrating Orion Health & HealthStat Systems Farhaan Mirza Surgical Outcome Calculator Luke Boyle Health Outcome Prediction Engine (HOPE) for Stroke Delwyn Armstrong Deep Representation Learning from Electronic Health Edmond Zhang Records Classification of Gait Patterns in Children with Oscar Moosman Cerebral Palsy using a Machine Learning Approach Smart Medication Reconciliation Randall Britten Smart Search Edmond Zhang Clinical Risk Assessments and Calculators Mirza Baig Spatio-Temporal Big Data Analysis of Adherence Feiyu Hu Behaviour in Chronic Disease Health Outcome Prediction Engine (HOPE) for AAA Quentin Thurier Information Consent Best Practice Rizwan Asghar Engaging Families in Precision Growth Assessment Gayl Humphrey A Patient's Journey for an Elective Surgery Mirza Baig

18 DATA FOR CLINICAL RESEARCH DOMINIC MORGAN

19 I have always stuck up for Western medicine. You can chew all the celery you want, but without antibiotics, three quarters of us would not be here. - HUGH LAURIE Page Orion Health group of companies

20 Laughter is the best medicine - unless you're diabetic, then insulin comes pretty high on the list. - JASPER CARROTT Page Orion Health group of companies

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23 Drying pipelines Stricter Regulation & Approvals Cost Containment by Payers How to transform into patientcentric organisation Stratified medicine Poor adherence Blockbuster Patent Expiries Page Orion Health group of companies 23

24 Clinical Trial Recruitment Understanding the need What is the best protocol? Where will we have the most success in finding patients? Trial Design Site Selection Patient Recruitment Trial Running Reporting What are the right clinical scenarios to find potential patients? Were there safety issues? Can any data be utilised from existing systems? Page Orion Health group of companies

25 Clinical Portal/ Shared Care Views Rhapsody queries Trial Design Clinical Trial Recruitment Where can we help? Cohort analysis? Multi-site queries? Type of patient Inclusion/exclusion criteria Site Selection Education Referrals/MDT s/clinics Enrollment & Information Patient Recruitment Consent Auto-population of data? Third party launch? Trial Running Reporting Clinical Portal MDT worklists Healthcare Pathways Page Orion Health group of companies

26 Post- Launch Observational Studies Page Orion Health group of companies

27 Post Launch How s the drug doing for me? Population Health Management Precision Medicine. All diabetics are the same Every person is unique Page Orion Health group of companies

28 Clinical Portal/ Shared Care Views Rhapsody queries Study Design Observational Study Same principles apply Cohort analysis? Multi-site queries? Type of patient Inclusion/exclusion criteria Site Selection Education Referrals/MDT s/clinics Enrollment & Information Patient Recruitment Consent Auto-population of data? Third party launch? Run Study Reporting Clinical Portal MDT worklists Healthcare Pathways Page Orion Health group of companies

29 Unleash power of more data & insights Platform for Innovation/Precise Health Stratified medicine Understand adherence Patientcentric organisation Benchmarking Performance How is therapy performing New Indications? PROMS & PREMS How am I feeling? Remote Monitoring Healthcare Captured Data 4 Citizen Captured & New Data Page Orion Health group of companies

30 4 reasons to care. 1. Improve patient care & patient experience using existing technology 2. Attract the best talent and researchers 3. Help to balance the deficit and generate income through increased research 4. Research driven innovations will seed use in routine clinical practice Page Orion Health group of companies

31 If we could make sense of health & care data for an entire population, patterns could be identified and evidence about the most successful medicines or treatments could be used to create an optimised precise plan for an individual. IAN MCCRAE CEO, Orion Health Page Orion Health group of companies

32 Data in action Open APIs for querying and integration with 3 rd party analytics Amadeus Analytics Engine for patient identification & stratification, and clinical quality measures The role of data in Clinical Research Page Orion Health group of companies