SAFETY DATA SHEET BIOTENE DRY MOUTH TOOTHPASTE

Transcription

1 SAFETY DATA SHEET 1. Identification Product identifier Other means of identification Synonym(s) Recommended use Recommended restrictions BIOTENE DRY MOUTH TOOTHPASTE MFC: LACLEDE L * PHOSPHATE, FORMULATED PRODUCT Oral Care other uses are advised. Manufacturer/Importer/Supplier/Distributor information Manufacturer 2. Hazard(s) identification Classified hazards GlaxoSmithKline US 5 Moore Drive Research Triangle Park, NC USA US General Information (normal business hours): Address: msds@gsk.com Website: EMERGENCY PHONE NUMBERS - TRANSPORT EMERGENCIES:: US / International toll call available 24 hrs/7 days; multi-language response Exempt from requirements - product regulated as a medicinal product, cosmetic product or medical device. Label elements Exempt from requirements - product regulated as a medicinal product, cosmetic product or medical device. Hazard(s) not otherwise classified (HNOC) Exempt from requirements - product regulated as a medicinal product, cosmetic product or medical device. 3. Composition/information on ingredients Mixtures Hazardous components Chemical name Common name and synonyms CAS number % CALCIUM PYROPHOSPHATE DI-SODIUM FLUOROPHOSPHATE DISODIUM FLUOROPHOSPHATE <1.0 DIPHOSPHATE DISODIUM PHOSPHOROFLUORIDATE SODIUM FLUOROPHOSPHATE (2PO3F) SODIUM PHOSPHOROFLUORIDATE SODIUM PHOSPHOROFLURIDATE GLUCOSE OXIDASE LACTOFERRIN LACTOPEROXIDASE LYSOZYME Other components below reportable levels > First-aid measures Inhalation Skin contact Eye contact Ingestion Most important symptoms/effects, acute and delayed Under normal conditions of intended use, this material is not expected to be an inhalation hazard. Rinse skin with water/shower. Get medical attention if irritation develops and persists. Rinse with water. Get medical attention if irritation develops and persists. Get medical advice/attention if you feel unwell. 1 / 6

2 Indication of immediate medical attention and special treatment needed General information 5. Fire-fighting measures Treat symptomatically. Get medical attention if symptoms occur. Suitable extinguishing media Water. Carbon dioxide (CO2). Dry powder. Foam. Unsuitable extinguishing media Specific hazards arising from the chemical Special protective equipment and precautions for firefighters Fire-fighting equipment/instructions 6. Accidental release measures Personal precautions, protective equipment and emergency procedures Methods and materials for containment and cleaning up Environmental precautions 7. Handling and storage ne known. t applicable. Wear suitable protective equipment. Use standard firefighting procedures and consider the hazards of other involved materials. Local authorities should be advised if significant spillages cannot be contained. Keep unnecessary personnel away. Keep people away from and upwind of spill/leak. Wear appropriate personal protective equipment. Ensure adequate ventilation. Stop the flow of material, if this is without risk. Following product recovery, flush area with water. For waste disposal, see section 13 of the MSDS. See Section 8 of the MSDS for Personal Protective Equipment. Avoid discharge into drains, water courses or onto the ground. Precautions for safe handling special control measures required for the normal handling of this product. rmal room ventilation is expected to be adequate for routine handling of this product. Conditions for safe storage, including any incompatibilities 8. Exposure controls/personal protection Occupational exposure limits GSK t established Room temperature - normal conditions. Store in original tightly closed container. US. OSHA Table Z-1 Limits for Air Contaminants (29 CFR ) Components Type US. OSHA Table Z-2 (29 CFR ) Components PEL Type 2.5 mg/m3 Form US. ACGIH Threshold Limit s Components TWA 2.5 mg/m3 Dust. Type TWA US. NIOSH: Pocket Guide to Chemical Hazards Components Type 2.5 mg/m3 Biological limit values TWA 2.5 mg/m3 ACGIH Biological Exposure Indices Components Determinant Specimen Sampling Time 3 mg/l Fluoride Urine * 2 / 6

3 ACGIH Biological Exposure Indices Components Determinant Specimen Sampling Time 2 mg/l Fluoride Urine * * - For sampling details, please see the source document. Appropriate engineering controls special ventilation requirements. Individual protection measures, such as personal protective equipment Eye/face protection Hand protection Other Respiratory protection Thermal hazards General hygiene considerations Wear safety glasses with side shields. t normally needed. special protective equipment required. personal respiratory protective equipment normally required. 9. Physical and chemical properties Appearance Odor Physical state Form Color Odor threshold ph Melting point/freezing point Initial boiling point and boiling range Flash point Evaporation rate Flammability (solid, gas) Wash hands before breaks and immediately after handling the product. Solid. Paste. Expected to be non-flammable based on components present. Upper/lower flammability or explosive limits Flammability limit - lower (%) Flammability limit - upper (%) Explosive limit - lower (%) Explosive limit - upper (%) Vapor pressure Vapor density Relative density Solubility(ies) Partition coefficient (n-octanol/water) Auto-ignition temperature Decomposition temperature Viscosity 10. Stability and reactivity Reactivity Chemical stability Possibility of hazardous reactions Conditions to avoid Incompatible materials Material is stable under normal conditions. dangerous reaction known under conditions of normal use. ne under normal conditions. 3 / 6

4 Hazardous decomposition products Irritating and/or toxic fumes and gases may be emitted upon the products decomposition. 11. Toxicological information Information on likely routes of exposure Ingestion Inhalation Skin contact Eye contact Symptoms related to the physical, chemical and toxicological characteristics Information on toxicological effects Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Respiratory sensitization Skin sensitization Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity - single exposure Specific target organ toxicity - repeated exposure Aspiration hazard Further information 12. Ecological information Ecotoxicity May be irritating to eyes. ne known. May be irritating to eyes. data available to indicate product or any components present at greater than 0.1% are mutagenic or genotoxic. Contains no ingredient listed as toxic to reproduction. ne known. ne known. ne known. information is available about the potential of this material to produce adverse environmental effects. Persistence and degradability data is available on the degradability of this product. Bioaccumulative potential Mobility in soil Mobility in general Other adverse effects 13. Disposal considerations Disposal instructions Hazardous waste code Waste from residues / unused products Contaminated packaging 14. Transport information DOT t regulated as a dangerous good. IATA t regulated as a dangerous good. IMDG t regulated as a dangerous good. Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code Do not allow this material to drain into sewers/water supplies. Dispose of contents/container in accordance with local/regional/national/international regulations. t regulated. Dispose of in accordance with local regulations. Empty containers or liners may retain some product residues. This material and its container must be disposed of in a safe manner (see: Disposal instructions). Since emptied containers may retain product residue, follow label warnings even after container is emptied. MARPOL Annex II applies to liquids used in a ship's operation that pose a threat to the marine environment. These materials may not be transported in bulk. 4 / 6

5 15. Regulatory information US federal regulations This product is not known to be a "Hazardous Chemical" as defined by the OSHA Hazard Communication Standard, 29 CFR TSCA Section 12(b) Export tification (40 CFR 707, Subpt. D) t regulated. CERCLA Hazardous Substance List (40 CFR 302.4) t listed. US. OSHA Specifically Regulated Substances (29 CFR ) t listed. SARA 304 Emergency release notification t regulated. Superfund Amendments and Reauthorization Act of 1986 (SARA) Hazard categories SARA 302 Extremely hazardous substance SARA 311/312 Hazardous chemical Other federal regulations Immediate Hazard - Delayed Hazard - Fire Hazard - Pressure Hazard - Reactivity Hazard - Clean Air Act (CAA) Section 112 Hazardous Air Pollutants (HAPs) List t regulated. Clean Air Act (CAA) Section 112(r) Accidental Release Prevention (40 CFR ) t regulated. Safe Drinking Water Act (SDWA) Food and Drug Administration (FDA) US state regulations t regulated. t regulated. US. Massachusetts RTK - Substance List t regulated. US. New Jersey Worker and Community Right-to-Know Act t regulated. US. Pennsylvania RTK - Hazardous Substances DI-SODIUM FLUOROPHOSPHATE (CAS US. Rhode Island RTK t regulated. US. California Proposition 65 t Listed. International Inventories Country(s) or region Inventory name On inventory (yes/no)* Australia Australian Inventory of Chemical Substances (AICS) Canada Canada China Europe Europe Japan Korea New Zealand Philippines Domestic Substances List (DSL) n-domestic Substances List (NDSL) Inventory of Existing Chemical Substances in China (IECSC) European Inventory of Existing Commercial Chemical Substances (EINECS) European List of tified Chemical Substances (ELINCS) Inventory of Existing and New Chemical Substances (ENCS) Existing Chemicals List (ECL) New Zealand Inventory Philippine Inventory of Chemicals and Chemical Substances (PICCS) United States & Puerto Rico Toxic Substances Control Act (TSCA) Inventory *A "Yes" indicates that all components of this product comply with the inventory requirements administered by the governing country(s) A "" indicates that one or more components of the product are not listed or exempt from listing on the inventory administered by the governing country(s). 5 / 6

6 16. Other information, including date of preparation or last revision Issue date Revision date Version # 02 Further information References Disclaimer Revision Information This material has not been assessed for HMIS or NFPA ratings. HMIS is a registered trade and service mark of the NPCA. GSK Hazard Determination The information and recommendations in this safety data sheet are, to the best of our knowledge, accurate as of the date of issue. thing herein shall be deemed to create any warranty, express or implied. It is the responsibility of the user to determine the applicability of this information and the suitability of the material or product for any particular purpose. Product and Company Identification: Product and Company Identification Composition / Information on Ingredients: Ingredients Physical & Chemical Properties: Transport Information: Agency Name, Packaging Type, and Transport Mode Selection 6 / 6