1. PRODUCT INFORMATION. Company undertaking Identification: Oxford Expression Technologies Ltd, Gipsy Lane Campus, Oxford OX3 0BP, UK

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1 Oxford Expression Technologies Ltd Oxford Brookes University Gipsy Lane Campus Oxford OX3 0BP UK t: +44 (0) f: +44 (0) e: Material Safety Data Sheet 1. PRODUCT INFORMATION Product name: baculofectin II Transfection Reagent Product code: / Company undertaking Identification: Oxford Expression Technologies Ltd, Gipsy Lane Campus, Oxford OX3 0BP, UK Customer service Emergency information office hours +44(0) Precautionary Labelling: The components of baculofectin II (< 0.65% by weight) are potentially harmful, although the chemical, physical, and toxicological properties have not been thoroughly investigated. Handle with care, and practice safe laboratory techniques. The information included within this MSDS pertains to ethanol, which is used as a solvent. 2. COMPOSITION/INFORMATION ON INGREDIENTS Hazardous/Non-hazardous Components Chemical Name CAS-No. EINECS-No Hazard Weight % Ethanol Highly Toxic, 80 Flammable Water Impurities and stabilizing additives which are themselves classified and which contribute to the classification of the substance: none Classification 3. HAZARDS IDENTIFICATION GHS Classification in accordance with 29 CFR 1910 (OSHA HCS): Flammable liquids (Category 2), H225 Indication of danger H225 Highly flammable liquid and vapour Page 1 of 5

2 H315 + H320 H335 TLV PEL Oral Rat LD 50 Carcinogenicity Causes skin and eye irritation May cause respiratory irritation N/A 7060 MG/KG Unknown 4. FIRST AID MEASURES Skin contact Eye contact Ingestion Inhalation Notes to physician Wash off immediately with plenty of water Wash thoroughly with water, also under eyelids No specific measure: never give anything by mouth to unconscious person No specific measure: move to fresh air Treat symptomatically 5. FIRE FIGHTING MEASURES Suitable extinguishing media Special protective equipment for fire fighters Dry chemical Wear self-contained breathing apparatus and protective suit 6. ACCIDENTAL RELEASE MEASURES Personal precautions Methods for clean up Use standard personal protective equipment Eliminate ignition sources. Soak up with inert absorbent material and place in a tightly sealed container for disposable. Flush area with water. 7. HANDLING AND STORAGE Handling Storage No special handling advice required Keep in properly labelled containers that are tightly closed. Keep away from sparks, flame and heat. Store at -20 C. Occupational exposure controls Exposure limits 8. EXPOSURE CONTROLS / PERSONAL PROTECTION Chemical Name NIOSH REL (TWA) OSHA PEL (TWA) Ethanol 1900 mg/m mg/m 3 Engineering measures Ensure adequate ventilation in confined areas Personal protective equipment Respiratory protection In case of inadequate ventilation wear suitable respiratory Page 2 of 5

3 Hand protection Eye protection Skin and body protection Hygiene measures equipment Standard laboratory gloves Safety glasses with side shields Lightweight protective laboratory coat Wash hands before leaving laboratory and other good hygiene practices Environmental exposure controls Prevent product from entering the drains by appropriate disposal into biohazard waste containers 9. PHYSICAL AND CHEMICAL PROPERTIES General Information Form Liquid Important Health Safety and Environmental Information Boiling point/range 80 C 176 F Melting point/range -144 C F Flash point 20.0 C 68 F Autoignition temperature 363 C 685 F Oxidising properties Water solubility Soluble 10. STABILITY AND REACTIVITY Stability Materials to avoid Stable Oxidising agents, acetyl chloride 11. TOXICOLOGICAL INFORMATION Acute Toxicity Chemical Name LD50 (oral, LC50 (inhalation, LC50 (inhalation, Ethanol 7,060 mg/kg (Rat) no data available 10h 20000ppm (Rat) Principle Routes of Exposure/ Potential Health effects Eyes Skin Inhalation Ingestion Mild eye irritation - 24h No skin irritation - 24h May be harmful if swallowed. Specific effects Carcinogenic effects Mutagenic effects Reproductive toxicity OSHA: No component of this product present at levels greater than or equal to 0.1% is identified as a carcinogen or potential carcinogen by OSHA. Page 3 of 5

4 Sensitisation Target organ effects 12. ECOLOGICAL INFORMATION Ecotoxicity effects Chemical Name Fish (LC50 / 96h) Aquatic plants (growth inhibition /96h) Ethanol >10,000 mg/l (rainbow trout) >13,400 mg/l (fathead minnow) 1,000 (Chlorella vulgaris) Microorganisms (toxicity threshold) 6,500 mg/l (Pseudomonas putida) Mobility Biodegradation Bioaccumulation Inherently biodegradable Does not bioaccumulate Dispose of in accordance with local regulations. 13. DISPOSAL CONSIDERATIONS 14. TRANSPORT CONSIDERATIONS IATA UN No Proper shipping name Ethyl Alcohol Hazard class Class 3 Packing group Packing group II Labels: Flammable Liquid Transport in bulk DOT Quantity Limitation - Passenger/Cargo: 1L; Cargo: 60L 15. REGULATORY INFORMATION This product has been classified as compliant to Regulation (EC) No. 1272/2008 (CLP) (amending Council Directives 67/548/EEC and 1999/45/EC) and Regulation (EC) 1907/2006 (REACH) (last amended by Regulation (EC) 2015/830). 16. OTHER INFORMATION This material is sold for research and development purposes only and is not for any human or animal therapeutic or clinical diagnostic use. It is not intended for food, drug, household, agricultural, or cosmetic use. An individual technically qualified to handle potentially hazardous chemicals must supervise the use of this material. The above information shall not be taken as being all inclusive and is to be used only as a guide. All materials and mixtures may be present unknown hazards and should be used with caution. Since OET Ltd cannot control the actual methods, volumes, or conditions of use, the Company shall not be held liable for any damages or losses resulting from the handling or from contact with the product as described herein. THE INFORMATION IN THIS MSDS DOES NOT CONSTITUTE A WARRANTY, EXPRESS OR IMPLIED, INCLUDING ANY IMPLIED WARRANTY OF MERCHANTABILITY OR FITNESS FOR ANY Page 4 of 5

5 PARTCULAR PURPOSE. END OF MATERIAL SAFETY DATA SHEET Revised and updated 1/1/2019 Page 5 of 5