INFORMATION SHEET n-butanol

Transcription

1 NAME OF SUBSTANCE GENERAL INFORMATION Producer: ZAK Spółka Akcyjna Address: skr. poczt. 163, ul. Mostowa 30A, Kędzierzyn-Koźle, Poland Phone: (operator) EC number: CAS number: Registration number: CHEMICAL IDENTIFICATION Customary name: Brand name: Chemical name: Molecular formula: n-butanol (BuOH) n-butanol (BuOH) Butan-1-ol C 4 H 10 O APPLICATIONS For the production of: esters (which are then used as solvents and flavouring agents), paints and lacquers (solvent, anti-blushing agent, fluidity improver and viscosity reducer for waterborne paints), plastic additives (plasticisers), melamine-formaldehyde resins and urea-formaldehyde resins (as a solvent or butylation agent), auxiliaries for agriculture (butylamines), floatation additives, and ethers of ethylene and propylene glycols. It is also used as: solvent (textile industry and paint and lacquer industry), extracting agent in the production of medicinals, component of anti-icing mixtures and anti-corrosion additives. In accordance with the REACH Regulation, the product may be used pursuant to the exposure scenarios for the applications as identified in MSDS. PAGE 1 OF 6

2 PHYSICAL-CHEMICAL PROPERTIES Appearance clear and colourless organic liquid Odour no data available Density 0.81 g/cm 3 Melting point Boiling point Flammability Explosive properties (-) 90 C 119 C This substance is flammable in case of contact with sources of ignition. This substance is not pyrophoric and no flammable gases are released on its contact with water. This substance contains no functional groups which would make it explosive. Vapour pressure 10 hpa (20 C) Molecular weight Water solubility Flash point 74 g/mol 66 g/l at 20 C 35 C Octanol/water partition coefficient 1 HEALTH RISK Consumer Risk for consumers is minimised since that substance is produced and handled under industrial conditions and in confined systems only. It is harmful by inhalation. It causes skin irritation and serious damage to eyes. It may cause: respiratory irritation, coughing, headache, weakness, dizziness, gastrointestinal discomfort, nausea, swoon and breathlessness. Worker Risk for workers is minimised since that substance is produced and handled under industrial conditions and in confined systems only. In case of unintentional exposure, a worker should follow the occupational safety recommendations as specified in MSDS. PAGE 2 OF 6

3 Assessment of harmful effects Acute toxicity Irritation/corrosion Sensitisation Harmful if swallowed. It is strongly irritating but not corrosive. Risk of serious skin irritation, and changes are not reversible. Causes serious damage to eyes, irreversible corneal opacification and conjunctival redness. Skin: no sensitisation. Respiratory: no data available. Repeated dose toxicity Sub-chronic tests demonstrated central nervous system depression which is a natural consequence of the action of alcohols. Hence, there is no need to classify butan-1-ol for its systemic toxicity under repeated dose conditions. Repeated skin contact may cause skin dryness. Carcinogenicity Toxicity for reproduction No data available. There is no evidence at present for carcinogenicity of n-butanol. Genotoxicity negative. The available data show that butan-1-ol is not genotoxic, neither in-vitro nor in-vivo, hence it is not subject to classification in accordance with Directives 67/548/EEC and 1272/2008/EC (CLP). ENVIRONMENTAL RISK Assessment of environmental safety Environmental assessment confirmed that the product may be handled safely at all stages: starting from its manufacture, going through industrial applications, and to the consumer use. Moreover, that substance does not undergo bioaccumulation and it is not environmentally persistent. Toxicity to aquatic organisms Biodegradation Bioaccumulation Assessment of PBT/vPvB properties The product has not been classified as environmentally harmful. The product is easily and quickly biodegradable in soil and water. No bioaccumulation is observed. Based on available data, n-butanol was found: to be easily biodegradable and not to meet the classification criteria for P or vp; not to undergo bioaccumulation and not to meet the classification criteria for B or vb; not to meet the classification criteria for T; hence, this substance has been classified as non-ptb and non-vpvb. PAGE 3 OF 6

4 EXPOSURE Human health Harmful if swallowed. It causes skin irritation and serious damage to eyes. It may cause respiratory irritation, drowsiness and dizziness. Environment In the environmental safety study, n-butanol was found environmentally safe at the stages of its manufacture, industrial applications and consumer use. RECOMMENDATIONS FOR RISK CONTROL Use gloves to protect your skin and hands. Wear safety goggles to protect your eyes. Do not eat in those places where any contact with the product may be expected. Wash hands and exposed skin areas after any contact with the product. After eye contact, rinse eyes with potable water for at least 15 minutes and seek medical assistance. LEGAL n-butanol has been registered with the European Chemicals Agency, pursuant to the requirements of REACH (Regulation (EC) 1907/2006). INFORMATION ON CLASSIFICATION AND LABELLING In the light of CLP (Regulation (EC) 1272/2008), substances are classified in accordance with the physical, health and environmental hazards as carried by them. The risk is presented in the form of special marking and Material Safety Data Sheets. The goal of CLP is to standardise the information on hazards in such a way that everybody involved (workers, consumers, transport staff, rescue men, etc.) can understand easily the specific risk(s) which results from the chemicals they use and/or are exposed to. PAGE 4 OF 6

5 GHS pictograms GHS02: flame GHS05: corrosion GHS07: exclamation mark acc. to RID/ADR: - shipping name BUTANOLS - UN number UN warning label 3 Flammable liquids or Hazard statements H226: Flammable liquid and vapour. H302: Harmful if swallowed. H335: May cause respiratory irritation. H315: Causes skin irritation. H318: Causes serious eye damage. H336: May cause drowsiness or dizziness. Precautionary statements P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/ / equipment. P242: Use only non-sparking tools. P280: Wear protective gloves/protective clothing/eye protection/ face protection. P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use water spray, alcohol-resistant fire foams and/or carbon dioxide for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P501: Dispose of adsorber material according to regulations. CONCLUSIONS Sources of information: Chemical Safety Report for n-butanol Material Safety Data Sheet for n-butanol CONTACT DATA For more information on that product please refer to our WEB site: PAGE 5 OF 6

6 VOCABULARY acute toxicity allergenic bioaccumulation biodegradable carcinogenicity chronic toxicity clastogen CSR embryotoxicity GHS hazard mutagenicity reproductive toxicity teratogenicity harmful effect(s) of single exposure capable of bringing on sensitisation accumulation of a substance in a biological system susceptible to degradation by biological processes ability to produce cancer harmful effect(s) of repeated exposure substance which can cause breaks in chromosomes Chemical Safety Report toxic effects on foetus Globally Harmonized System situation which poses a level of threat to life, health or environment capacity to induce genetic mutations teratogenicity, embryotoxicity and harmful impact on fertility put together; adverse effects on reproductive systems capability of producing foetal malformations Date when created 26/10/2011 Version: 1 PAGE 6 OF 6