SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 Version 2.0 Revision Date

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1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1 Product identifiers Product name : RunBlue MES & MOPS Run Buffer SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 Version 2.0 Revision Date Product Number : NXB70500, NXB75500 Brand : Expedeon REACH No. : A registration number is not available for this substance as the substance or its uses are exempted from registration, the annual tonnage does not require a registration or the registration is envisaged for a later registration deadline. 1.2 Relevant identified uses of the substance or mixture and uses advised against Identified uses : Laboratory chemicals, Manufacture of substances, research 1.3 Details of the supplier of the safety data sheet Company : Expedeon Ltd. Unit 12 Buckingway Business Park Anderson Road CB24 4AE Swavesey Cambridgeshire UNITED KINGDOM Telephone : +44 (0) Fax : +44 (0) address : info@expedeon.com 1.4 Emergency telephone number Emergency Phone # : +44 (0) SECTION 2: Hazards identification 2.1 Classification of the substance or mixture Classification according to Regulation (EC) No 1272/2008 Not Hazardous For the full text of the H-Statements mentioned in this Section, see Section 16. Classification according to EU Directives 67/548/EEC or 1999/45/EC Not Hazardous For the full text of the R-phrases mentioned in this Section, see Section Label elements Labelling according Regulation (EC) No 1272/2008 Pictogram Signal word Hazard statement(s) Page 1 of 7

2 Precautionary statement(s) Supplemental Hazard Statements According to European Directive 67/548/EEC as amended. Hazard symbol(s) 2.3 Other hazards - SECTION 3: Composition/information on ingredients 3.2 Mixtures Component Classification Concentration CAS-No. EC-No Reach No XXXX Flam. Sol. 2 - H228Tox. 4 - H302Irrit. 2 - H315Dam. 1 - H318SE 3 - H335Chronic 3 - H % For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16 SECTION 4: First aid measures 4.1 Description of first aid measures General advice Consult a physician. Show this safety data sheet to the doctor in attendance. If inhaled If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician. In case of skin contact Wash off with soap and plenty of water. Consult a physician. In case of eye contact Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician. If swallowed Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician. Page 2 of 7

3 4.2 Most important symptoms and effects, both acute and delayed The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in section Indication of any immediate medical attention and special treatment needed SECTION 5: Firefighting measures 5.1 Extinguishing media Suitable extinguishing media Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide. 5.2 Special hazards arising from the substance or mixture 5.3 Advice for firefighters Wear self contained breathing apparatus for fire fighting if necessary. 5.4 Further information SECTION 6: Accidental release measures 6.1 Personal precautions, protective equipment and emergency procedures Use personal protective equipment. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. For personal protection see section Environmental precautions Do not let product enter drains. 6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material and dispose of as hazardous waste. Keep in suitable, closed containers for disposal. 6.4 Reference to other sections For disposal see section 13. SECTION 7: Handling and storage 7.1 Precautions for safe handling Avoid contact with skin and eyes. Avoid inhalation of vapour or mist. For precautions see section Conditions for safe storage, including any incompatibilities Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Recommended storage temperature: 2-8 C 7.3 Specific end use(s) Apart from the uses mentioned in section 1.2 no other specific uses are stipulated SECTION 8: Exposure controls/personal protection 8.1 Control parameters Components with workplace control parameters Chemical Name EU OEL (TWA) EU OEL (STEL) EU Skin Notation None None None Page 3 of 7

4 Chemical Name Austria Belgium (TWA) Denmark (TWA) Finland OEL (TWA) Chemical Name France OEL (VME) Germany OEL (TWA) Ireland (TWA) Italy OEL (TWA) Chemical Name Sweden - Occupational Exposure Limits - TLVs (LLVs) Netherlands OEL (MAC) Spain OEL (TWA) United Kingdom Chemical Name European Union United Kingdom France OEL (VME) Germany OEL (TWA) Chemical Name Italy OEL (TWA) Portugal Netherlands OEL (MAC) Finland OEL (TWA) Chemical Name Austria Denmark Poland Switzerland Chemical Name Ireland Norway Lithuania OEL (TWA) Spain OEL (TWA) Engineering measures Ensure adequate ventilation, especially in confined areas. Page 4 of 7

5 8.2 Exposure controls Appropriate engineering controls Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Personal protective equipment Eye/face protection Tightly fitting safety goggles. Faceshield (8-inch minimum). Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Skin protection Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique (without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it. Body Protection Complete suit protecting against chemicals, The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Respiratory protection Where risk assessment shows air-purifying respirators are appropriate use a full-face respirator with multi-purpose combination (US) or type ABEK (EN 14387) respirator cartridges as a backup to engineering controls. If the respirator is the sole means of protection, use a full-face supplied air respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Control of environmental exposure Do not let product enter drains. SECTION 9: Physical and chemical properties 9.1 Information on basic physical and chemical properties a) Appearance Form: liquid b) Odour c) Odour Threshold d) ph e) Melting point/freezing point f) Initial boiling point and boiling range g) Flash point h) Evapouration rate i) Flammability (solid, gas) j) Upper/lower flammability or explosive limits k) Vapour pressure l) Vapour density m) Relative density n) Water solubility Page 5 of 7

6 o) Partition coefficient: n- octanol/water p) Auto-ignition temperature q) Decomposition temperature r) Viscosity s) Explosive properties t) Oxidizing properties 9.2 Other safety information SECTION 10: Stability and reactivity 10.1 Reactivity 10.2 Chemical stability Stable under recommended storage conditions Possibility of hazardous reactions 10.4 Conditions to avoid 10.5 Incompatible materials 10.6 Hazardous decomposition products Other decomposition products - In the event of fire: see section 5 SECTION 11: Toxicological information 11.1 Information on toxicological effects Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Respiratory or skin sensitisation Germ cell mutagenicity Carcinogenicity IARC: Reproductive toxicity No component of this product present at levels greater than or equal to 0.1% is identified as probable, possible or confirmed human carcinogen by IARC. Specific target organ toxicity - single exposure Page 6 of 7

7 Specific target organ toxicity - repeated exposure Aspiration hazard Additional Information RTECS: Not available To the best of our knowledge, the chemical, physical, and toxicological properties have not been thoroughly investigated. Kidney - Irregularities - Based on Human Evidence (Glycerol) Liver - Irregularities - Based on Human Evidence (Tris(2-hydroxyethyl)ammonium chloride) SECTION 12: Ecological information Toxicity Chemical Name Freshwater Algae Data Water Flea Data Freshwater Fish Species Data Microtox Data log Pow Pseudokirchneriella Daphnia magna logpow1.6 subcapitata EC EC50=1.8 mg/l (48 h) mg/l (96 h) Pseudokirchneriella subcapitata EC50=117 mg/l (96 h) Desmodesmus subspicatus EC mg/l (96 h) Desmodesmus subspicatus EC50=53 mg/l (72 h) Persistence and degradability No information available. Bioaccumulative potential No information available. Results of PBT and vpvb assessment This mixture does not contain any substances that are assessed to be a PBT or a vpvb. Other adverse effects No information available. SECTION 13: Disposal considerations 13.1 Waste treatment methods Product Offer surplus and non-recyclable solutions to a licensed disposal company. Contaminated packaging Dispose of as unused product. SECTION 14: Transport information 14.1 UN number ADR/RID: - IMDG: - IATA: UN proper shipping name ADR/RID: Not dangerous goods IMDG: Not dangerous goods IATA: Not dangerous goods 14.3 Transport hazard class(es) ADR/RID: - IMDG: - IATA: Packaging group ADR/RID: - IMDG: - IATA: - Page 7 of 7

8 14.5 Environmental hazards ADR/RID: no IMDG Marine pollutant: no IATA: no 14.6 Special precautions for user Page 8 of 7

9 SECTION 15: Regulatory information This safety datasheet complies with the requirements of Regulation (EC) No. 1907/2006. Safety, health and environmental regulations/legislation specific for the substance or mixture Substances of Very High Concern None. Restricted substances under EC 1907/2006, Annex XVII Substances listed under Annex I of Regulation (EC) No 689/2008 None. Restricted substances under Annex V of Regulation (EC) No 689/2008 None. Substances under Regulation (EC) No 850/2004 of the European Parliament and of the Council of 29 April 2004 on persistent organic pollutants and amending Directive 79/117/EEC None. German Water hazard classes (Wassergefährdungsklassen) Chemical Name Weight percent Germany - Water Classification (VwVwS) Annex 1 Germany - Water Classification (VwVwS) - Annex 2 - Water Hazard Classes Germany - Water Classification (VwVwS) Annex hazard class 2 - hazard to waters Other International Inventories Chemical Name EINECS ELINCS ENCS PICCS Listed - Listed Listed Chemical Name AICS KECL DSL NDSL Listed Listed Listed - SECTION 16: Other information No chemical safety assessment has been carried out. Further information The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. Expedeon and its Affiliates shall not be held liable for any damage resulting from handling or from contact with the above product. See and/or the reverse side of invoice or packing slip for additional terms and conditions of sale. Page 9 of 7