CURRICULUM VITAE. Department of Geosciences (609)

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1 Page 1 of 6, CV, Dr. Xinning Zhang CURRICULUM VITAE Xinning Zhang, Ph.D. Associate Research Scholar xinningz@princeton.edu Department of Geosciences (609) Princeton University Guyot Hall Princeton, NJ Education Cornell University Ithaca, NY Biological & Environmental Engineering B.S., 2004 Caltech Pasadena, CA Environmental Science & Engineering M.S., 2007 Caltech Pasadena, CA Environmental Science & Engineering Ph.D., 2010 Professional Experience 2014-present Associate Research Scholar, Dept. of Geosciences, Princeton University I. Constraints on alternative N 2 fixation. II. Genetic basis of bacterial siderophore production Postdoctoral Research Associate, Dept. of Geosciences, Princeton University Trace metals in the nitrogen cycle - development of new isotopic tools to study environmental N 2 fixation. Advisors: F. Morel, A. Kraepiel Postdoctoral Research Scholar, Environmental Science and Engineering, Caltech Genetic basis for the metabolic control of hydrogen stable isotope content in bacterial lipids. Advisor: A.L. Sessions Graduate Research Fellow, Environmental Science and Engineering, Caltech I. Trace element effects on gene diversity in the symbiotic gut microbial communities of lignocellulose-feeding insects. Advisor: J.R. Leadbetter. II. Metabolic impacts on the hydrogen isotope content of bacterial lipids. Advisor: A.L. Sessions Summer student, Marine Biological Laboratory (Woods Hole, MA) Microbial Diversity Course. Instructors: T. Schmidt, W. M. Metcalf Undergraduate researcher, Cornell University. I. Biodegradability of metal-chelators in hydroponic systems. Advisor: B. Ahner (Dept. of Biological & Environmental Eng) II. Characterization of lake derived organic polymers for use as slow-sand filter aids in drinking water treatment. Advisor: M. Weber-Shirk. (Dept. of Civil & Environmental Eng.) Honors and Research Grants 2015 Princeton Environmental Institute - Andlinger Research Award for Energy and the Environment.

2 Page 2 of 6, CV, Dr. Xinning Zhang , Tuttle Family Invertebrate Research Fund, Dept. Geosciences, Princeton Univ. & Benjamin Rosen Graduate Student Fellowship, Caltech 2004 National Science Foundation Graduate Research Fellowship 2004 B.S. summa cum laude, Cornell University (2004) Cornell Presidential Research Scholar Teaching Experience Teaching assistant, Microbial Physiology, Caltech. (2006, 2007, 2008) Duties included designing laboratory experiments, helping students to design and monitor individual research projects, writing and grading problem sets, office hours and review sessions. Teaching assistant, Engineering Thermodynamics, Cornell University (Fall 2003) Duties included grading problem sets, office hours and review sessions. Mentor for undergraduate research (Princeton, 2014 present; Caltech, 2011) Synergistic Activities Co-Coordinator for Environmental Geology and Geochemistry Seminar Series. Dept. of Geosciences, Princeton University ( ) Princeton Women in Geosciences (member 2013-present, steering committee ) Caltech Women Mentoring Women Program ( ) Reviewer for Applied and Environmental Microbiology, Environmental Microbiology, FEMS Microbiology, Geobiology, Geochimica et Cosmochimica Acta, Organic Geochemistry, PNAS, Nature, NSF Professional Memberships American Society of Microbiology, American Geophysical Union Publications in Refereed Journals in review Darnajoux R., Zhang X., McRose D., Miadlikowska J., Lutzoni F., Kraepiel A.M.L, Bellenger J.P. (in review) Alternative nitrogenases contribute to biological nitrogen fixation in boreal cyanolichens. New Phytologist _ 1) Zhang X., McRose D. L., Darnajoux R., Bellenger J.-P., Morel F.M.M., Kraepiel. A.M.L. (2016) Alternative nitrogenase activity in the environment and nitrogen cycle implications. Biogeochemistry. DOI: /s _ 2) Baars O, Zhang X., Morel F.M.M., Seyedsayamdost M. (2015) The siderophore metabolome of Azotobacter vinelandii. Applied and Environmental Microbiology DOI:

3 Page 3 of 6, CV, Dr. Xinning Zhang /AEM ) Zhang X., Sigman D.M., Morel F.M.M., Kraepiel A.M.L. (2014) Nitrogen isotope fractionation by alternative nitrogenases and past ocean anoxia. PNAS 111(13): DOI: /pnas ) Bellenger J.P., Xu Y., Zhang X., Morel F.M.M., Kraepiel A.M.L. (2014) Possible contribution of alternative nitrogenases to nitrogen fixation by asymbiotic N 2 -fixing bacteria in soils. Soil Biology and Biochemistry 69(0): DOI: /j.soilbio ) Rosenthal A.Z.*, Zhang X.*, et al. (2013) Localizing transcripts to single cells suggests an important role of uncultured deltaproteobacteria in the termite gut hydrogen economy. Proceedings of the National Academy of Sciences 110 (40): *equal contributors. DOI: /pnas ) Matson E.G., Rosenthal A.Z., Zhang X., Leadbetter J.R. (2013) Genome-wide effects of selenium and translational uncoupling on transcription in the termite gut symbiont Treponema primitia. mbio 4(6). DOI: /mBio _2012 7) Zhang X. and Leadbetter J.R. (2012) Evidence for cascades of perturbation and adaptation in the metabolic genes of higher termite gut symbionts. mbio 3(4): e DOI: /mBio _2011 8) Zhang X., Matson E.G., Leadbetter J.R. (2011) Genes for selenium dependent and independent formate dehydrogenase in the gut microbial communities of 3 lower, woodfeeding termites and a wood-feeding roach. Environmental Microbiology 13(2): DOI: /j x up to ) Matson E.G., Zhang X., Leadbetter J.R. (2010) Selenium controls transcription of paralogous formate dehydrogenase genes in the termite gut acetogen, Treponema primitia. Environmental Microbiology 12: DOI: /j x 10) Zhang X., Gillespie A. L., Sessions A.L. (2009) Large D/H variations in bacterial lipids reflect central metabolic pathways. Proceedings of the National Academy of Sciences 106: DOI: /pnas (PNAS Feature article, Journal Cover, Article commentary) 11) Warnecke F., Luginbühl P., Ivanova N., Ghassemian M.,, Zhang X., et al. (2007) Metagenomic and functional analysis of hindgut microbiota of a wood-feeding higher termite. Nature 450: DOI: /nature06269 (Editor s Choice, Nature News & Views commentary, Faculty of 1000 recommendation) 12) Vadas T.M., Zhang X., Curran A.M., Ahner B.A. (2007) Fate of DTPA, EDTA and EDDS in hydroponic media and effects on plant mineral nutrition. Journal of Plant

4 Page 4 of 6, CV, Dr. Xinning Zhang Nutrition 30: DOI: / Oral presentations 1) Zhang X., McRose D. L., Darnajoux R., Bellenger J.P., Morel F.M.M., Kraepiel A.M.L. (Dec. 2015) Isotopic biomarkers of nitrogenase metalloenzymes: Forging links between the cycles of nitrogen and trace metals. American Geophysical Union, San Francisco, CA. (session Bio-isotopic message in a (rock record) bottle, Invited talk) 2) Zhang X. (Dec. 2015) The importance of alternative N 2 fixation in the past and present. (University of Pennsylvania, Philadelphia, Invited talk) 3) Zhang X., McRose D., Darnajoux R., Bellenger J.P., Sigman, D.M., Morel F.M.M., and Kraepiel A.M.L. (Nov., 2015) The importance of N 2 fixation by alternative nitrogenases for budgets and beyond. (NOAA-GFDL, Princeton, Invited talk) 4) Zhang X. (Nov., 2015) The importance of alternative N 2 fixation in the past and present. (American University, Washington DC, Invited talk) 5) Zhang X., et al. (Nov., 2015) The importance of alternative nitrogenases in N 2 fixation in the past and present (Microbial Systems Seminar Series, Parsons Lab, MIT, Invited talk) 6) Zhang X., et al. (Nov., 2015) The importance of alternative nitrogenases in N 2 fixation in the past and present (Dept. of Environmental Sciences, Rutgers University, Invited talk) 7) Zhang X., McRose D., Darnajoux R., Bellenger J.P., Sigman, D.M., Morel F.M.M., and Kraepiel A.M.L. (Oct., 2015) From metalloenzymes to ecosystem: trace metals in the nitrogen cycle. (Civil and Environmental Engineering, Temple University, Invited talk) 8) Zhang X. (Oct., 2015) The importance of alternative nitrogenases in N 2 fixation in the past and present (Environmental Geology and Geochemistry Seminar Series, Princeton University) 9) Zhang, X. (2011) Adventures in biogeochemistry: from gene surveys of termite gut microbes to hydrogen stable isotopes in lipids. (Geoscience department, Princeton University, NJ.) 10) Zhang X., Matson EM, and Leadbetter J.R. (2011) Genetic signals for the dynamic evolution of termite gut bacterial symbionts. (Remsen-Bird lecture, Occidental College, CA, Invited talk) 11) Zhang, X., Gillespie, A. L., and Sessions, A.L. (2010) The hydrogen isotopic composition of bacterial lipids: an isotopic biomarker of energy metabolism? (West Coast Bacterial Physiologists Meeting, Asilomar, USA.) 12) Zhang, X. and Sessions, A.L. (2009) D/H fractionation and bacterial metabolism. (19 th V.M. Goldschmidt Conference, Davos, Switzerland, Invited talk- declined) 13) Zhang, X., Sessions, A.L. (2008) Variations in D/H fractionation associated with microbial heterotrophy and autotrophy. (Geobiology Symbiosium, University of Southern California, Los Angeles, USA.) 14) Zhang X., Matson, E.G., and Leadbetter, J.R. (2006) Formate dehydrogenase diversity in the homoacetogenic spirochete Treponema primitia and in termite hindgut microbial communities suggests their adaptation to a changing selenium environment. (West Coast Bacterial Physiologists Meeting, Asilomar, USA.) Published Abstracts and Poster Presentations (*presenter) 1) Zhang X.*, McRose D., Darnajoux R., Bellenger J.P., Morel F.M.M., and Kraepiel A.M.L. (Oct., 2015) Forging links between the cycles of nitrogen and trace metals using

5 Page 5 of 6, CV, Dr. Xinning Zhang stable isotope biomarkers of nitrogenase metalloenzymes (Poster, 19 th International Nitrogen Fixation Conference, Asilomar, CA) 2) Zhang X.*, McRose D., Darnajoux R., Bellenger J.P., Morel F.M.M., and Kraepiel A.M.L. (2015) Coupled Biogeochemistry of Nitrogen and Trace Metals: Isotopic Acetylene Reduction Assay (ISARA) Indicates Significant Alternative Nitrogenase Usage in the Environment. (Poster, Carbon Mitigation Initiative Annual Meeting, Princeton, NJ). 3) Zhang X.*, McRose D., Darnajoux R., Bellenger J.P., Morel F.M.M., and Kraepiel A.M.L. (2015) Coupled Biogeochemistry of Nitrogen and Trace Metals: Isotopic Acetylene Reduction Assay (ISARA) Indicates Significant Alternative Nitrogenase Usage in the Environment. (Poster, American Society of Microbiology Annual Meeting, New Orleans, Louisiana). 4) McRose D.*, Zhang X., Darnajoux R., Bellenger J.P., Morel F.M.M., and Kraepiel A.M.L. (2015) Diverse Assemblages of Alternative Nitrogenases are Present and Active in Coastal Sediments. (Poster, American Society of Microbiology Annual Meeting, New Orleans, Louisiana) 5) Zhang X.*, McRose D., Darnajoux R., Bellenger J.P., Morel F.M.M., and Kraepiel A.M.L. (2015) Isotopic Acetylene Reduction Assay (ISARA) Indicates Significant Alternative Nitrogenase Usage in the Environment. (Poster, Northeastern Geobiology Conference, Princeton, NJ.) 6) Zhang X.*, Sigman D.M., Morel F.M.M., and Kraepiel A.M.L. (2013) Isotope fractionation by alternative nitrogenases and past ocean anoxia. (Poster, American Geophysical Union, San Francisco, CA.) 7) Zhang X., Sigman D.M., Morel F.M.M., and Kraepiel A.M.L.* (2013) Isotope fractionation by alternative nitrogenases and past ocean anoxia. (Talk, Goldschmidt Conference, Florence, Italy) 8) Zhang, X., Sessions, A.L.*, Gillespie, A. L. (2008) Huge variations in D/H fractionation associated with microbial heterotrophy. (Poster, 18 th V.M. Goldschmidt Conference, University of British Columbia, Vancouver, Canada.) 9) Zhang X.*, Matson, E.G., and Leadbetter, J.R. (2008) Formate dehydrogenase diversity in the homoacetogenic spirochete Treponema primitia and in termite hindgut microbial communities suggests their adaptation to a changing selenium environment. (Poster, 2 nd Conference on Beneficial Microbes, American Society for Microbiology, San Diego, USA.) 10) Zhang X.*, Matson, E.G., and Leadbetter, J.R. (2007) Formate dehydrogenase diversity in the homoacetogenic spirochete Treponema primitia and in termite hindgut microbial communities suggests their adaptation to a changing selenium environment. (Poster, 161 th meeting, Society for General Microbiology, Edinburgh, Scotland.) 11) Matson, E. G.*, Zhang, X., and Leadbetter, J. R. (2007) Selenium controls transcription of Sec and Cys variants of formate dehydrogenase in a homoacetogenic termite gut spirochete. (Poster, 161 th meeting, Society for General Microbiology, Edinburgh, Scotland.)