Clinical, Forensic & Toxicology

Transcription

1 Reference Standards 10 Critical Steps to World-Class CRMs Compound Index for Reference Standards Single-Component Solutions Column & Detector Test Mixes & Reagents Deactivating Agent Derivatization Reagents Detector Tuning Mixes GC Column & Detector Test Mixes GPC Calibration Mixes LC Column & Detector Test Mixes Index of Reference Standards by Industry Clinical, Forensic & Toxicology Blood Alcohol Exempted Drugs of Abuse Explosives Fire Debris Analysis Personal Care Products Ethylene Oxide Polyethylene Glycol (PEG) Weathered Petrochemical Environmental Acetates Alcohols Aldehydes Base, Neutral & Acid Extractable (BNA) Benzidines BTEX Diesel Fuel Disinfection By-Products Drinking Water Odor Ethylene Oxide Explosives Gases Gasoline Glycols Haloacetic Acids Herbicides Chloroacetanilide Herbicide Degradates Chlorinated Acid Glyphosate Paraquat/Diquat Triazines or

2 Hormones Hydrocarbons Aromatic Hydrocarbons Halogenated Hydrocarbons Leaking Underground Storage Tank (LUST) Polycyclic Aromatic Hydrocarbons (PAHs) Petroleum Hydrocarbons Fuels & Products Aviation Gas BTEX Creosote Oil Diesel Fuel Oil Gasoline Hydraulic Oil Jet Fuel Kerosene Leaking Underground Storage Tank (LUST) Mineral Spirits Motor Oil Stoddard Solvent Retention Time Markers Total Petroleum Hydrocarbons (TPH) Weathered Petrochemical Isocyanates Jet Fuel Kerosene Ketones Leaking Underground Storage Tank (LUST) Nitriles Nitroaromatics & Nitramines Nitrosamines Oil & Grease Organometallics/Organotin Oxygenates/Ethers Pesticides Carbamate Chlordane & Toxaphene Chlorinated Disinfection By-Products, Pesticides & Herbicides Chlorinated/Organochlorine/Organohalide Nitrogen & Phosphorus Organophosphorus Pesticides & Flame Retardants Phenylurea State-Specific Phenols Phthalates (Phthalate Esters) Polybrominated Diphenyl Ethers (PBDEs) Polychlorinated Biphenyls (PCBs) PCB Aroclors PCB Congeners Polycyclic Aromatic Hydrocarbons (PAHs) Semivolatile Organics Toxicity Characteristic Leaching Procedure (TCLP) Trihalomethanes Volatile Organics or

3 Environmental Reference Standards International-Specific Canada Europe Japan ISO/DIS Foods, Flavors & Fragrances Derivatization Reagents Fatty Acid Methyl Esters (FAMEs) Fatty Acids Food Analysis Performance Assessment Scheme (FAPAS ) Fragrance Allergens Fragrances Medical Cannabis Melamine MN Dept of Agriculture Pesticides Multiresidue Pesticides GC Pesticides Kit LC Pesticides Kit Packaging Phthalate Esters Plastic Container Testing Polycyclic Aromatic Hydrocarbons (PAHs) QuEChERS Petroleum & Petrochemical Biodiesel Finished Motor Oil & Aviation Gasoline Leaking Underground Storage Tank (LUST) PCBs in Transformer Oil Simulated Distillation Spark Ignition Engine Fuels Pharmaceutical Diethylene & Ethylene Glycol Fatty Acids Pharmaceutical Compounds in Drinking Water Plastic Container Testing Residual Solvents Index of Reference Standards by Method Source American Oil Chemists Society (AOCS) Methods AOCS Method CE 1-62 Fatty Acid Methyl Esters FAMEs Association of Analytical Communities (AOAC) International Methods QuEChERS American Society for Testing & Materials (ASTM) Methods D2887 Simulated Distillation Petroleum Fractions D3606 Benzene & Toluene in Finished Motor & Aviation Gasoline D3710 Simulated Distillation D4059 PCBs in Insulating Liquids D5197 Formaldehyde and Other Carbonyl Compounds in Air D5836 2,4-Toluene Diisocyanate (2,4-TDI) and 2,6-Toluene Diisocyanate (2,6-TDI) in Workplace Atmospheres D6042 Phenolic Antioxidants & Erucamide Slip Additives in Polypropylene Homopolymer Formulations (Plastic Container Testing)...572, 583 D6352 High-Temperature Simulated Distillation or

4 D6584 Total Monoglyceride, Total Diglyceride, Total Triglyceride & Free & Total Glycerin in B100 Biodiesel Methyl Esters Biodiesel D6730 Individual Components in Spark Ignition Engine Fuels E1387 Ignitable Liquid Residues in Extracts From Fire Debris Samples Using GC E1618 Ignitable Liquid Residues in Extracts From Fire Debris Samples Using GC-MS Canadian Council of Ministers of the Environment (CCME) Methods CCME Petroleum Hydrocarbons Canadian Drinking Water Atlantic RBCA European Norm (EN) Methods EN14105 Biodiesel European Pharmacopeia (EP) EP Fatty Acids by GC...565, 583 EP/ICH Residual Solvents Fragrance Materials Association (FMA) Essential Oils Test Mix ISO/DIS 9377 Water Quality Testing Minnesota Department of Agriculture MN Dept. of Agriculture Pesticides OSHA/NIOSH Industrial Hygiene (IH) Methods ASTM Method D /OSHA 42, OSHA 47, NIOSH 5522 (Analysis of Isocyanates in Indoor Air by LC) Standard Methods for the Analysis of Water and Wastewater 5560 Organic and Volatile Acids U.S. EPA Methods 500 SERIES METHODS U.S. EPA SAFE DRINKING WATER ACT (SDWA) Method 501, 501.2, Trihalomethanes Method 502.1, Volatile Halogenated Organics Method Ethylene Dibromide & Dibromochloropropane Method 505 Organohalide Pesticides & PCBs Method 506 Phthalate & Adipate Esters Method 507 Nitrogen & Phosphorus Pesticides Method 508 Chlorinated Pesticides Method 515, Chlorinated Acid Herbicides Method 521 Nitrosamines Method 522 1,4-Dioxane Method 524.1, 524.2, Volatile Organics Method 525, 525.1, Semivolatile Organics Method 527 Pesticides & Flame Retardants (GC-MS) Method 528 Phenols Method 531.1, Carbamates Method 532 Phenylurea Pesticides Method 535 Chloroacetanilide Herbicide Degradates Method 539 Hormones in Drinking Water Method 547 Glyphosate Method Paraquat/Diquat Method Chlorinated Pesticides & Herbicides Method 552, 552.1, 552.2, Haloacetic Acids & Dalapon Method 555 Chlorinated Acids or

5 600 SERIES METHODS U.S. EPA CLEAN WATER ACT (CWA) Method 601 Purgeable Hydrocarbons Method 603 Acrolein & Acrylonitrile...518, 551 Method 604 Phenols Method 605 Benzidine & 3,3'-Dichlorobenzidine Method 606 Phthalate Esters Method 607 Nitrosamines Method 608 Organochlorine Pesticides & PCBs Method 609 Nitroaromatics & Isophorone...486, 495 Method 610 Polycyclic Aromatic Hydrocarbons (PAHs) Method 612 Chlorinated Hydrocarbons Method 615 Chlorinated Acid Herbicides Method 624 Purgeable Halocarbons...496, Method 625 Semivolatiles Tuning Mixes Aroclors Chlordane & Toxaphene...521, 526 Method Total Recoverable Petroleum Hydrocarbons Method 1311 Toxicity Characteristic Leaching Procedure (TCLP)...494, 544 Method 1614 Polybrominated Diphenyl Ethers (PBDEs) Method 1664 Oil & Grease Method 3500 Organic Extraction Surrogates SERIES METHODS RESOURCE CONSERVATION & RECOVERY ACT (RCRA) SOLID WASTE MANUAL (SW-846) Method 8010 Halogenated Volatile Organics...496, 552 Method ,2-Dibromoethane & 1,2-Dibromo-3-Chloropropane...496, 553 Method 8020 Aromatic Volatile Organics...495, 553 Method 8021 Volatile Organics Method 8040 Phenols Method 8061A Phthalate Esters Method 8080, 8081 Chlorinated Pesticides Method 8082, 8082A Polychlorinated Biphenyls (PCBs) Method 8095 Explosives by GC Method 8100 Polycyclic Aromatic Hydrocarbons (PAHs) Method 8140, 8141 Organophosphorus Pesticides Method 8150, 8151, 8151A Chlorinated Acid Herbicides Method 8240 Volatile Organic Compounds (VOCs)...488, Method 8260, 8260A, 8260B Volatile Organic Compounds (VOCs) Method 8270C, 8270D Semivolatile Organic Compounds (SVOCs) Method 8310 Polycyclic Aromatic Hydrocarbons (PAHs) by LC Method 8315 Aldehydes & Ketones DNPH by LC Method 8321 Chlorinated Acids by LC Method 8330 Nitroaromatics and Nitramines by LC CLP METHODS CERCLA/SUPERFUND PROGRAM Method SOM01.1, 04.2, 04.1, 10/92 SOW Volatiles (QA) Method 04.2, 04.1, 3/90 SOW, OLC 03.2 Volatiles (Calibration) Method SOM01.1, 04.2, 04.1, 4/89 & 3/90 SOW, Low Concentration Semivolatiles (QA) Method SOM01.1, 04.2, 04.1, 4/89 & 3/90 SOW, 03.2 Low Concentration Semivolatiles (Calibration) Method SOM01.1, 04.2, 04.1, 03.2, 3/90, 4/89 & 2/88 SOW Pesticides (QA) Method SOM01.1, 04.2, 04.1, 03.2, 3/90, 4/89 & 2/88 SOW Pesticides (Calibration) Aroclors Chlordane & Toxaphene...521, 526 GPC Calibration Mixes PCB Congeners or

6 STATIONARY SOURCE & AMBIENT AIR METHODS ASTM D CARB TO-11A Aldehydes & Ketones...483, 518 TO-14 VOCs TO Ozone Precursors/PAMS LEAKING UNDERGROUND STORAGE TANK (LUST) RECOVERY ACT PROGRAM METHODS General Diesel/Biodiesel Standard Diesel Surrogates & Internal Standards Fuel Composite Standards Fuel Oil Degradation Test Gasoline Surrogate & Internal Standards Retention Time Standards Military Fuels (Jet Propellant) Mineral Spirits Motor Oil Composite Standards Petroleum Volatile Organic Compounds (PVOCs), Gasoline Range Organics (GRO) & Benzene-Toluene-Ethylbenzene-Xylenes (BTEX) Single-Source Fuels Weathered Fuels State-Specific Methods Alaska Arizona California Connecticut Florida Massachusetts Michigan Mississippi New Jersey Northwest U.S. (Oregon & Washington) Pennsylvania Tennessee & Mississippi Texas Washington Wisconsin U.S. Pharmacopeia (USP) USP <467> Residual Solvents Compound Index for Reference Standards See pages or

7 10 Critical Steps World-Class Certified What are Certified Reference Materials (CRMs)? A CRM from Restek is in an exclusive subset of reference standards that meets the following set of strict criteria defined under ISO Guide 34 and ISO/IEC 17025: Made of raw materials characterized via qualified methods on qualified instruments. Produced in an ISO-accredited lab under documented procedures. Falls under the manufacturer s scopes of accreditation. To learn more about Restek s ISO quality credentials and to view our certificates (including scopes of accreditation), visit CRITICAL STEPS Whether it s a stock, off-the-shelf reference standard or a one-of-a-kind, custom-formulated solution, there are 10 critical steps that Restek takes to separate our certified reference materials (CRMs) from the competition. For every CRM produced in Restek s ISO-accredited labs, we always: Review Customer & Method Requirements To determine which organic reference standards we should develop as stock products, Restek experts closely monitor government regulations and methods from around the globe and also actively engage with our customers and distributors. Once a product is chosen based on regulatory changes, customer needs, and our 20+ years of experience, a veteran Restek chemist formulates a stable standard containing an ideal mix of compounds and concentrations. All formulations are then subjected to a thorough review of accuracy, compatibility, and solubility by a second chemist. Ver i fy Com pat i bil i ty & Sta bil i ty All raw materials used in our reference standards are held to strict purity criteria, and compound compatibility is scrutinized during both formulation and review. We also conduct on-going, long-term stability and short-term shipping stability studies in accordance with ISO Guide 34 and ISO Guide 35 to ensure reliability and accurate shelf-life reporting. Characterize Raw Materials Thoroughly Restek s Quality Control (QC) lab confirms the chemical identity and purity of mixture components and solvents using one or more of the following techniques: GC-FID, HPLC, GC-ECD, GC-MS, LC-MS, refractive index, and melting point. Calibrate Analytical Balances All analytical balances are verified at seven mass levels daily using NIST* traceable weights and are also calibrated yearly by an ISO/IEC 17025:2005 accredited provider to guarantee accurate measurement. Deactivate Glassware & Ampuls Restek reference standards are prepared using Class A volumetric flasks and/ or Class A pipettes. Ampuls and vials used in preparation and packaging are deactivated to prevent the loss of target analytes. Maintain ISO Accreditation In 2011, the reference standard manufacturing and QC testing laboratories in Restek s state-of-the-art Bellefonte, PA, facility earned ISO Guide 34 and ISO/IEC accreditation. These accreditations in addition to ISO 9001 registration, which we have maintained since 1994 serve as recognition that Restek and our labs meet the world-class quality standards established by the International Organization for Standardization (ISO). On-site manufacturing as well as raw material, qualitative, and quantitative analyses are completed in these ISO-accredited labs. Restek s ISO-accredited labs offer a full line of both stock and custom CRMs. * National Institute of Standards and Technology or

8 10 Critical Steps Reference Materials (CRMs) Offer a Variety of Documentation Restek exclusively offers three levels of fully ISO-compliant documentation for our CRMs, and most stock CRMs come with quantitative-level documentation. Gravimetric: Product supplied with the gravimetric records listing purity of each material used, calculated concentration, and a unique lot number. Qualitative (Certificate of Composition): A sample withdrawn from the packaged units is tested by the appropriate technique to verify mixture composition. Product supplied with a certificate of composition showing a chromatogram of the standard with each peak identified, raw material purity, and gravimetric concentration. Quantitative (Certificate of Analysis): A sample of the packaged unit is analyzed in triplicate and the peak areas are statistically compared to a previous lot (if available) or a second lot. A detailed data pack is available at containing gravimetric documentation, all quantitative assay raw data, exact amount of each raw material used, total volume prepared, and statistics. Test results for raw material purity and identification are available upon request. Documentation for all of your stock and custom Restek CRMs is a few clicks away at Package Securely & Label Clearly Every Restek CRM is placed in durable, high-quality packaging for dockto-door protection. Labeling provides critical storage, safety, and shelf life information in an easy-to-read format and now features bar-coded GHS labeling for added safety and easier compliance. Protect Product Quality After Opening To help preserve the integrity of our CRMs after they are opened, we include a deactivated screw-top vial (cat.# 24640) with each stock reference standard <5 ml for worry-free transfer and reliable temporary storage. Manage Warehouse Inventory To ensure the inventory is available when it s needed, Restek continually analyzes and maintains inventory of more than 1,500 catalog standards as well as multiple lots of the most commonly requested calibration standards. We pull inventory months before its expiration date to eliminate inadvertent delivery of expired or nearly expired reference standards. Need a Custom CRM? Our ISO-Accredited Labs Can Supply Them! In addition to an extensive selection of reference standards that is in-stock and ready to ship, Restek s custom-formulated solutions also fall under our ISO Guide 34 and ISO/IEC accreditations. Satisfy all of your certified reference material needs as well as order GC and LC columns, sample prep supplies, and accessories using one reliable supplier: Restek. Request a quote for your custom reference standards today! Visit Save Up to 75% on Custom CRMs! Establish a Blanket / Standing Order Today Significant cost savings. Fewer purchase orders and invoices. Less instrument downtime. Reduced inventory management. Flexibility to adjust to changing needs. Contact Customer Service or your local Restek representative to learn more and start saving! or