SECTION 1: Identification of the substance/mixture and of the company/undertaking. SECTION 2: Hazards identification Product identifier

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1 K-INOSL Date of issue: 11/03/2014 Revision date: 13/03/2017 Supersedes: 11/03/2014 Version: 1.1 S SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Product identifier Product form : Liquid Name : myo-inositol 1.2. Relevant identified uses of the substance or mixture and uses advised against Relevant identified uses Industrial/Professional use spec Use of the substance/mixture : Industrial For professional use only : Use as laboratory reagent Uses advised against 1.3. Details of the supplier of the safety data sheet Megazyme, Bray Business Park, Bray, Co. Wicklow, A98 YV29, Ireland. T F cs@megazyme.com Emergency telephone number Emergency number : Country Official advisory body Address Emergency number IRELAND (REPUBLIC OF) UNITED KINGDOM SECTION 2: Hazards identification National Poisons Information Centre Beaumont Hospital National Poisons Information Service (Birmingham Centre) City Hospital 2.1. Classification of the substance or mixture Classification according to Regulation (EC) No. 1272/2008 [CLP] Eye Irrit. 2 H319 Full text of H-phrases: see section 16 Classification according to Directive 67/548/EEC or 1999/45/EC Not classified Adverse physicochemical, human health and environmental effects 2.2. Label elements Labelling according to Regulation (EC) No. 1272/2008 [CLP] Hazard pictograms (CLP) : Beaumont Hospital Beaumont Road Dublin 9 Dudley Road Birmingham B18 7QH (UK only) Signal word (CLP) Hazard statements (CLP) Precautionary statements (CLP) GHS07 : Warning : H319 - Causes serious eye irritation : P264 - Wash Both hands thoroughly after handling P280 - Wear eye protection P305+P351+P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing P337+P313 - If eye irritation persists: Get medical advice/attention 13/03/2017 EN (English) 1/6

2 2.3. Other hazards SECTION 3: Composition/information on ingredients 3.1. Substances 3.2. Mixture Name Product identifier % Classification according to Directive 67/548/EEC glycylglycine (CAS No) (EC No) Xi; R36 Name Product identifier % Classification according to Regulation (EC) No. 1272/2008 [CLP] glycylglycine (CAS No) (EC No) Full text of R-, H- and EUH-phrases: see section Eye Irrit. 2, H319 SECTION 4: First aid measures 4.1. Description of first aid measures First-aid measures general First-aid measures after inhalation First-aid measures after skin contact First-aid measures after eye contact First-aid measures after ingestion : Never give anything by mouth to an unconscious person. If you feel unwell, seek medical advice (show the label where possible). : Ensure fresh air breathing. Allow the victim to rest. : Remove affected clothing and wash all exposed skin area with mild soap and water, followed by warm water rinse. : Rinse immediately with plenty of water. Obtain medical attention if pain, blinking or redness persists. : Rinse mouth. Do NOT induce vomiting. Obtain emergency medical attention Most important symptoms and effects, both acute and delayed Symptoms/injuries : Not expected to present a significant hazard under anticipated conditions of normal use Indication of any immediate medical attention and special treatment needed SECTION 5: Firefighting measures 5.1. Extinguishing media Suitable extinguishing media : Foam. Dry powder. Carbon dioxide. Water spray. Sand. Unsuitable extinguishing media : Do not use a heavy water stream Special hazards arising from the substance or mixture 5.3. Advice for firefighters Firefighting instructions Protection during firefighting : Use water spray or fog for cooling exposed containers. Exercise caution when fighting any chemical fire. Avoid fire-fighting water entering the environment. : Do not enter fire area without proper protective equipment, including respiratory protection. SECTION 6: Accidental release measures 6.1. Personal precautions, protective equipment and emergency procedures For non-emergency personnel Emergency procedures For emergency responders Protective equipment Emergency procedures : Evacuate unnecessary personnel. : Equip cleanup crew with proper protection. : Ventilate area Environmental precautions Prevent entry to sewers and public waters. Notify authorities if liquid enters sewers or public waters Methods and material for containment and cleaning up Methods for cleaning up : Soak up spills with inert solids, such as clay or diatomaceous earth as soon as possible. Collect spillage. Store away from other materials. 13/03/2017 EN (English) 2/6

3 6.4. Reference to other sections See Heading 8. Exposure controls and personal protection. SECTION 7: Handling and storage 7.1. Precautions for safe handling Precautions for safe handling 7.2. Conditions for safe storage, including any incompatibilities Storage conditions Incompatible materials 7.3. Specific end use(s) SECTION 8: Exposure controls/personal protection 8.1. Control parameters : Wash hands and other exposed areas with mild soap and water before eating, drinking or smoking and when leaving work. Provide good ventilation in process area to prevent formation of vapour. : Keep only in the original container in a cool, well ventilated place. Keep container closed when not in use. : Sources of ignition. Direct sunlight Exposure controls Personal protective equipment Hand protection Eye protection Respiratory protection : Avoid all unnecessary exposure. : Wear protective gloves. : Chemical goggles or safety glasses. : Wear appropriate mask. : Do not eat, drink or smoke during use. SECTION 9: Physical and chemical properties 9.1. Information on basic physical and chemical properties Physical state : Liquid Colour : Colourless Odour : Characteristic Odour threshold ph Relative evaporation rate (butylacetate=1) Melting point Freezing point Boiling point Flash point Self ignition temperature Decomposition temperature Flammability (solid, gas) Vapour pressure Relative vapour density at 20 C Relative density Solubility Log Pow Log Kow Viscosity, kinematic Viscosity, dynamic Explosive properties Oxidising properties Explosive limits 9.2. SECTION 10: Stability and reactivity Reactivity. 13/03/2017 EN (English) 3/6

4 10.2. Chemical stability Possibility of hazardous reactions Conditions to avoid Direct sunlight. Extremely high or low temperatures Incompatible materials Strong bases Hazardous decomposition products Fume. Carbon monoxide. Carbon dioxide. SECTION 11: Toxicological information Information on toxicological effects Acute toxicity Skin corrosion/irritation Serious eye damage/irritation Respiratory or skin sensitisation Germ cell mutagenicity Carcinogenicity Reproductive toxicity Specific target organ toxicity (single exposure) Specific target organ toxicity (repeated exposure) Aspiration hazard Potential adverse human health effects and symptoms SECTION 12: Ecological information Toxicity Persistence and degradability K- INSOL Bottle 4 Persistence and degradability glycylglycine ( ) Persistence and degradability Biodegradability in water: no data available Bioaccumulative potential K-INSOL Bottle 4 Bioaccumulative potential glycylglycine ( ) Bioaccumulative potential Mobility in soil Results of PBT and vpvb assessment 13/03/2017 EN (English) 4/6

5 12.6. Other adverse effects : Avoid release to the environment SECTION 13: Disposal considerations Waste treatment methods Waste disposal recommendations : Dispose in a safe manner in accordance with local/national regulations. Ecology - waste materials : Avoid release to the environment. SECTION 14: Transport information In accordance with ADR/RID/ADNR/IMDG/ICAO/IATA UN number Not dangerous goods in sense of transport regulations UN proper shipping name Transport hazard class(es) Packing group Environmental hazards : No supplementary information available Special precautions for user Overland transport Transport by sea Air transport Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code SECTION 15: Regulatory information Safety, health and environmental regulations/legislation specific for the substance or mixture EU-Regulations No REACH Annex XVII restrictions Contains no REACH candidate substance National regulations Chemical safety assessment No chemical safety assessment has been carried out SECTION 16: Data sources : REGULATION (EC) No 1272/2008 OF THE EUROPEAN PARLIAMENT AND OF THE COUNCIL of 16 December 2008 on classification, labelling and packaging of substances and mixtures, amending and repealing Directives 67/548/EEC and 1999/45/EC, and amending Regulation (EC) No 1907/2006. : None. Full text of R-, H- and EUH-phrases:: Eye Irrit. 2 Serious eye damage/eye irritation, Category 2 H319 Causes serious eye irritation R36 Xi Irritating to eyes Irritant SDS EU (REACH Annex II) 13/03/2017 EN (English) 5/6

6 This information is based on our current knowledge and is intended to describe the product for the purposes of health, safety and environmental requirements only. It should not therefore be construed as guaranteeing any specific property of the product. 13/03/2017 EN (English) 6/6