Material Safety Data Sheet PEGcure

Transcription

1 Section 1 Chemical Product and Company Identification MSDS Name: Catalog Numbers: N/A Synonyms: IRGACURE 2959 Company Identification: Glycosan BioSystems PO Box 2321 Park City, UT For information, call: Manufacture Identification: Ciba Corporation 540 White Plains Road P.O. Box 2005 Tarrytown, NY Section 2 Composition, Information on Ingredients CAS# Chemical Name Percent EINECS/ELINCS IRGACURE % unlisted Hazard Symbols: None listed. Risk Phrases: None listed. Section 3 Hazards Identification EMERGENCY OVERVIEW Appearance: White to Yellow Solid. The toxicological properties of this material have not been fully investigated. Caution! Avoid contact and inhalation. Target Organs: None known. For additional information on toxicity, please refer to Section 11. Section 4 First Aid Measures Eyes: Check for contact lenses and remove if present. Flush thoroughly with water while opening eyelids. If symptoms such as redness and irritation persist, obtain medical attention. Skin: Wash material from skin with soap and water and rinse thoroughly with clean water. Obtain medical attention as needed or if irritation develops. Ingestion: Do not induce vomiting; if vomiting occurs naturally, have casualty lean forward to reduce the risk of aspiration. Obtain Medical attention immediately. Inhalation: Remove person from source then obtain necessary medical attention. If breathing is difficult give oxygen and immediate medical attention Notes to Physician: Treat symptomatically and supportively.

2 Section 5 Fire Fighting Measures General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Extinguishing Media: Use agent most appropriate to extinguish fire. Suitable: Water spray. Carbon dioxide, dry chemical powder, or appropriate foam. Flash Point: N/A Autoignition Temperature: N/A Flammability: Non-flammable Unusual Fire and Explosion Hazards: As with any organic material, this product may produce toxic carbon monoxide and dioxide fumes if heated to decomposition and airborne dust may present an explosion hazard. Section 6 Accidental Release Measures General Information: Exercise appropriate precautions to minimize direct contact with skin or eyes and prevent inhalation of dust. Spills/Leaks: Wear protective clothing and gloves. Vacuum or collect spill into appropriate waste container for disposal. Use normal clean-up procedures for liquid spillage and wash thoroughly with water. Wash contaminated clothing before reuse. Section 7 Handling and Storage Handling: As with all industrial chemicals, use good industrial practices when handleing. Avoid eye, skin, and clothing contact. Do not inhale. Do not tate or swallow, Use only with adequate ventilation. Storage: Keep containers tightly closed in cool, well-ventilated place Explosion Hazards: - Combustible powder. - Avoid creating dusty conditions. - Grounding is required when emptying into a conductive container. - When flammable solvents are present, the container must be inerted or the system otherwise designed to prevent or contain an explosion. Seek expert advice. In addition, for products packaged in fused-lined (coated) fiber drums, fiber drums with conductive liners, steel drums, steel pails, and Type "C" FIBC (bulk bags), or other conductive the following instructions also apply: - Always ground this package before emptying. The user is responsible for designing the system to handle solid and ensuring proper training of employees in the system's use.

3 Section 8 Exposure Controls, Personal Protection Engineering Controls: None listed. Exposure Limits: None listed. OSHA Vacated PELs: None listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respiratory: Use NIOSH approved respirator as needed to mitigate exposure. General Hygiene Measures: Wash thoroughly after handling. Ventilation: Required Section 9 Physical and Chemical Properties Physical State: Solid Appearance: White to Yellow Odor: N/D ph: Vapor pressure: ~2 x 10(-5) 20 C Vapor density: N/A Evaporation Rate: N/A Viscosity: N/A Boiling Point: 331 C (628 F) Freezing/Melting Point: C ( F) Decomposition Temperature: > 350 C (662 F) Solubility: N/D Specific Gravity/Density: 1.28 Molecular Formula: N/A Molecular Weight: N/A N/A = not available N/D = not determined Section 10 Stability and Reactivity Chemical Stability: Stable Conditions to Avoid: Static Discharge Incompatibilities with Other Materials: Strong oxidizing agents, strong acids, strong bases Hazardous Decomposition Products: No decomposition expected under normal storage conditions Hazardous Polymerization: Not expected

4 Section 11 Toxicological Information Routes of Exposure Eye: May cause eye irritation. Skin: May cause skin irritation. Ingestion: May be harmful if swallowed. Inhalation: May be harmful if inhaled. Material may be irritating to mucous membranes and upper respiratory tract. Signs and Symptoms of Exposure The chemical, physical, and toxicological properties have not been fully investigated. Toxicity Data Acute Oral Toxicity: (Rats) LD50: 3,108 mg/kg (males and females); 4,032 mg/kg (males); 2,098 mg/kg (females). Reversible clinical signs included tremors, convulsions and locomotor disturbances. Acute Dermal Toxicity: (Rats) LD50 > 5,000 mg/kg Acute Inhalation Toxicity: Not determined Eye Irritation: (Rabbits) Not an irritant. Skin Irritation: (Rabbits) Not an irritant. Skin Sensitization: (Guinea Pig) Maximization test: Not a sensitizer (0/20 positive) Carcinogenicity (IARC; NTP; OSHA; ACGIH): None of the components in this product at concentrations greater than 0.1% are Page: 5 / listed by IARC; NTP, OSHA or ACGIH as a carcinogen. Mutagenicity: Ames / E. coli test: Non-mutagenic Cytogenetic test in V79 cells (in vitro): Nonmutagenic Reproductive Toxicity: Not determined Teratogenicity: Not determined Neurotoxicity: Not determined Subacute Toxicity: Not determined Subchronic Toxicity: 28-Day oral toxicity (Rats): The test substance was administered by gavage at doses of 0, 64, 160, 400 and 1,000 mg/kg/day. The only toxicologic effect seen was increased hepatocellular degeneration in high-dose males. The no observable effect level (NOEL) was 400 mg/kg/day. Chronic toxicity: Not determined Absorption / Distribution / Excretion / Metabolism: Not determined Additional Information: Not determined

5 Section 12 Ecological Information Toxicity to Fish: (Zebra fish) 96 hour LC50 >100 mg/l Toxicity to Invertebrates: (Daphnia magna) 48 hour EC50: 615 ppm Toxicity to Algae: (Green algae) 0-72 hour EC50: 2.6 ppm Toxicity to Sewage Bacteria: Inhibitory concentration on respiration of aerobic waste water bacteria: IC20, IC50, IC80 >100 ppm Activated Sludge Respiration Inhibition Test: Not determined Biochemical Oxygen Demand (BOD): Not determined Chemical Oxygen Demand (COD):Not determined Total Oxygen Demand (TOD): Not determined Biodegradability: Modified Sturm test: Not readily biodegradable, with 24 % in 28 days. Bioaccumulation: Not determined Additional Environmental Data: Not determined Section 13 Disposal Considerations 1. Dispose of waste in accordance with all applicable Federal, State and local regulations. 2. Chemical residues are generally classified as special waste and, as such, the transportation, storage, treatment and disposal of this waste material must be conducted in compliance with all applicable Federal, State and local regulations. 3. Rinse empty containers thoroughly before disposal and/or recycling. Non-hazardous for transport. Section 14 Transport Information Section 15 Regulatory Information General Information For research and development use only. Not for drug, household, or other uses. European/International Regulations Safety Phrases: S: 22 24/25 Do not breathe dust. Avoid contact with skin and eyes. US Label Text US Statement: Caution: Avoid contact and inhalation. United States Regulatory Information OSHA Hazardous Substance: This material is classified as not hazardous under OSHA regulations Clean Air Act - Hazardous Air Pollutants (HAP): This product does not contain any Hazardous Air Pollutants (HAP),

6 as defined by the U.S. Clean Air Act Section 112 (40 CFR 61). Clean Air Act - Volatile Organic Compounds (VOC): This product does not contain any SOCMI Intermediate or Final Volatile Organic Compounds (VOC), as defined by the U.S. Clean Air Act Section 111 (40 CFR ). Clean Air Act - Ozone Depleting Substances (ODS): This product neither contains, nor was manufactured with, a Class I or Class II ozone depleting substance (ODS), as defined by the U.S. Clean Air Act Section 602 (40 CFR 82, Subpt. A, App. A+B). Clean Water Act - Priority Pollutants (PP): This product does not contain any priority pollutants listed under the U.S. Clean Water Act Section 307 (2)(1) Priority Pollutant List (40 CFR ). Resource Conservation and Recovery Act (RCRA): Not a hazardous waste under RCRA (40 CFR ). SARA Section 302 Extremely Hazardous Substances (EHS): This product does not contain any components regulated under Section 302 (40 CFR 355) as Extremely Hazardous Substances. SARA Section 304 CERCLA Hazardous Substances: This product does not contain any components regulated under Section 304 (40 CFR 302) as hazardous chemicals for emergency release notification ("CERCLA" List). SARA Section 311/312 Hazard Communication Standard (HCS): This product is not regulated under Section 311/312 HCS (40 CFR 370). SARA Section 313 Toxic Chemical List (TCL): This product does not contain any component(s) listed on the Section 313 Toxic Chemical List. Page: 7 / TSCA Section 8(b) Inventory Status: All component(s) comprising this product are either exempt or listed on the TSCA inventory. TSCA Section 5(e) Consent Orders: This product is not subject to a Section 5(e) Consent Order. TSCA Significant New Use Rule (SNUR): This product is not subject to a Significant New Use Rule (SNUR). TSCA Section 5(f): This product is not subject to a Section 5(f)/6(a) rule. TSCA Section 12(b) Export Notification: This product does not contain any component(s) that are subject to a Section 12(b) Export Notification Canada Regulatory Information N/A

7 MSDS Creation Date: 2/18/10 Section 16 Additional Information The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Glycosan BioSystems Inc. be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Glycosan BioSystems Inc has been advised of the possibility of such damages.