Product Stewardship Summary Hexamethylenediamine

Transcription

1 Product Stewardship Summary Hexamethylenediamine General Statement Hexamethylenediamine is colorless solid with extensive uses in manufacturing of resins. It is used in the production of paper products, water treatment resins, adhesives, and many other applications. While hexamentylenediamine is both an acute contact and respiratory hazard, it is handled under stringent safety conditions to control the risk of exposure to both humans and the environment. Thus, consumer risks to hexamethylenediamine is not expected. Chemical Identity Name: Hexamethylenediamine Brand Names: Kymene and Crepetrol Chemical name (IUPAC): Hexane-1,6-diamine CAS number(s): EC number: Molecular formula: C 6 H 16 N 2 Structure: Uses and Applications Hexamethylenediamine is used mainly for the manufacture of unmodified resins, water treatment resins, resins used in paper manufacture and adhesive resins. Application of hexamethylenediamine is solely industrial product based, and consumers are unlikely to come into contact with it. Registered trademark, Ashland or its subsidiaries, registered in various countries TM Trademark, Ashland or its subsidiaries, registered in various countries * Trademark owned by a third party 2016, Ashland

2 Physical/Chemical Properties Phys/Chem Safety Assessment Hexamethylenediamine is not classified as physical and chemical hazards according to EU regulation (EC) 1272/2008. Property Value Form Crystalline powder Physical state Solid at 20ºC and at atmospheric pressure Color Colorless to White Odor Strong amine odor Density g/cm 20 C Melting / boiling point C / 205 C Flammability Not flammable Explosive properties Not explosive Self-ignition temperature 315 C Vapor pressure C Mol weight g/mol Water solubility C, readily soluble Flash point 85 at atmospheric pressure Octanol-water partition coefficient (LogPow) 25ºC, low potential for bioaccumulation Health Effects Human Health Safety Assessment Consumer: There is no intended use of hexamethylenediamine in consumer products. Therefore, consumer risk to hexamethylenediamine is negligible. Worker: Hexamethylenediamine is corrosive to skin and can cause serious eye damage. It may be irritating to the upper respiratory tract. It is harmful if swallowed or in contact with skin. Effect Assessment Acute Toxicity Oral / inhalation / dermal Irritation / corrosion Skin / eye / respiratory test Toxicity after repeated exposure Oral / inhalation / dermal Genotoxicity / Mutagenicity Carcinogenicity Toxicity for reproduction Result H302: Harmful if swallowed H312: Harmful in contac with skin H314: Causes severe skin burns and eye damage H335: May cayse respiratory irritation May cause irritation of the upper respiratory tract after repeated exposure Neither mutagenic or genotoxic No carcinogenic effects expected No adverse effect on fertility and development

3 Environmental Effects Environmental Safety Assessment Based on the available data, hexamethylenediamine is considered harmful to only aquatic invertebrates. It is readily biodegradable and not potentially bioaccumulative. Aquatic Toxicity Effect Assessment Result H402: Harmful to aquatic life (invertebrates) Not harmful to fish and algae Fate and behavior Biodegradation Readily biodegradable Bioaccumulation potential Not potentially bioaccumulative (log Kow = 0.4) PBT / vpvb conclusion Not considered to be either PBT or vpvb Exposure Human Health There is no forseeable exposure to consumers to hexamethylenediamine, as it is not present in any consumer products. In industrial settings, hexamethylenediamine is manufactured and hanfled as much as possible in closed processes which ensure that worker exposure to heaxamethylenediamine is minimized. When there is potential for exposure, during loading, unloading, sampling or during maintenance operations, exposure to hexamethylenediamine can be further minimized by the proper use of personal protective equipment. Environment Hexamethylenediamine is water soluble and biodegradable, and has low potential for bioaccumulation. It also has low potential for volatilization. Based on its physical and chemical properties, if hexamethylenediamine was released into the environment, it would be mainly distributed in water and would not be persistent in the environment. Risk Management Recommendations Exposure to hexamethylenediamine in the workplace can be controlled by sufficient ventilation, proper handling and storage techniques, and appropriate personal protective equipment as recommended in the SDS. A selection of occupational exposure limits are below. OEL TLV: 0.5 ppm as TWA ACGIH TLV: (8h TWA): 0.5 ppm WEEL: (8h TWA): 5 mg/m 3 Regulatory Agency Review Hexamethylenediamine is on the AICS Australian Inventory of Chemical Substances Hexamethylenediamine is on DSL Supplement to Canada Gazette, Part 1 Hexamethylenediamine is on REACH REACH: List of Registered Substances Hexamethylenediamine is on EINECS Annex to Official Journal of the European Communities Hexamethylenediamine is on ENCS Japanese Gazette Hexamethylenediamine is on ECL Korean Existing Chemicals List Hexamethylenediamine is on NZIoC New Zealand Inventory of Chemicals Hexamethylenediamine is on PICCS Philippines Inventory of Chemicals and Chemical Substances

4 Regulatory Information / Classification and Labeling Under the Globally Harmonized System for classification and labeling (GHS), substances are classified according to their physical, health, and environmental hazards. The hazards are communicated via specific labels and the (Extended) SDS. GHS attempts to standardize hazard communication so that the intended audience (workers, consumers, transport workers, and emergency responders) can better understand the hazards of the chemicals in use. GHS Classification: Acute oral toxicity Category 4 Acute toxicity, Dermal, Category 4 Skin corrosion, Ctegory 1B Specific taget organ toxicity single exposure, Category 3 Hazard Statements: H315: Causes skin irritation H302: Harfum if swallowed H312: Harful if contac with skin H314: Causes severe skin burns and eye damage H335: May cyase respiratory irritation Signal Word: Danger Precautionary Statements: P260: Do not breathe dust/ fume/ gas/ mist/ vapors/ spray P280: Wear protective gloves/ protective clothing/ eye protection/ face protection P301 + P330 + P331 IF SWALLOWED: rinse mouth, DO NOT induce vomiting P303 + P361 + P353 IF ON SKIN (or hair): Remove/ Take off immediate all contaiminated clothing. Rinse skin/ (hair) with water/ shower. P305 + P351 + P338 IF IN EYES: Rinse cautiously with water for severa minutes. Remove contact lenses, if present and easy to do so. Continue rinsing. P310: Immediate call a POISON CENTER or doctor/ physician. Hazard Pictograms: Conclusion Hexamethylenediamine is a useful chemical in the manufacturing of resins used in the production of paper products, water treatment resins, adhesives, and many other applications. When handled responsibly, the potential for skin and respiratory sensitization can be minimized, allowing consumers and workers to use materials containing hexamethytlenediamine safely.

5 Contact Information with Company Ashland Inc Blazer Parkway Dublin, Ohio Date of Issue: October 17, 2016 Revision: 1 Additional Information For more information on GHS, visit or Ashland product stewardship summaries are located at Disclaimer All statements, information and data presented herein are believed to be accurate and reliable, but are not to be taken as a guarantee, an express warranty, or an implied warranty of merchantability or fitness for a particular purpose, or representation, express or implied, for which Ashland Inc. and its subsidiaries assume legal responsibility. REACH registration is specific to Importers/Manufacturers that place the chemical on the EU market, and specific to registered uses. Inclusion on the list of REACH Registered Substances does not automatically imply registration by Ashland. Inclusion on the New Zealand Inventory of Chemicals applies only to the pure substance listed. The importer of record must determine whether or not their substances are in compliance.