Présentation Corporate Juin 2013 BEAT THE COMPETITION WITH PRECELLYS EVOLUTION. Webinar #10 Friday 31 st October 2014 BT.D46.D. Une société du Groupe

Transcription

1 BEAT THE COMPETITION WITH PRECELLYS EVOLUTION Webinar #10 Friday 31 st October 2014

2 YOUR SPEAKERS TODAY ARE 2 Quitterie Brossard Application Marketing Manager Armelle Chavanet - Product Manager Assistant

3 WEBINAR ORGANIZATION & RULES 1) Your microphone will be muted during the presentation to minimize the interferences 3 2) If you have questions or remarks during the presentation, please write it in the questions tab. After the presentation, the speakers will answer to your questions.

4 AGENDA 4 I) Reminder of bead-beating benefits II) Precellys Evolution: Analysis of main competitors III) Precellys commercial claims IV) Available tools and support

5 PRECELLYS FAMILY OF PRODUCTS 5 The only high quality, efficient and comprehensive solution for sample preparation High throughput Routine and R&D High throughput Routine work Flexible Affordable Cooling option Protects sensitive molecules 25 different lysing kits, Empty tubes & beads in bulk

6 BEAD-BEATING BENEFITS Comparison to other methods

7 TRADITIONAL SAMPLE PREPARATION METHODS Sonicator Principle: create micro-bubbles to crush samples Good for liquid phase samples, micro-organism Not good for plant, animal, human tissues, hard samples, etc. Pain point: unavoidable cleaning step & poor reproducibility 7 Mortar & Pestle Principle: mechanical & manual grinding Good for hard and frozen sample Not good for: large samples & multiple Pain point: unavoidable cleaning step & poor reproducibility and low throughput Blade mixer: Principle: rotated blades to cut samples Good for hard and tough sample Not good for micro-organisms Pain point: unavoidable cleaning step & low throughput

8 BEAD-BEATING BENEFITS Sample homogenization needs: Simplicity High yield extraction Reproducibility Throughput Nothing to clean Bead-beating answers: Disrupt any sample in ~30 sec Standardization Prepare multiple samples at once Cross-contamination free 8 Productivity improvement

9 BEAD-BEATING VS OTHER METHODS 9 ~30sec for all type of samples Hard, soft, elastic Animal, plant, µbio Same grinding quality/efficiency for each tube 24 x 2mL 12 x 7mL 6 x 15mL

10 PRECELLYS COMPETITION

11 PRINCIPAL COMPETITORS 11 Main: FastPrep, Beadruptor, Beadblaster24, Powerlyser, Tissue Lyser II Others: Magnalyser, Genogrinder, FastPrep96, CryoMill, SpeedMill

12 FASTPREP24-5G - MP BIOMEDICAL, USA POOR quality - 100% plastic: Hole between operating area and mechanical part + breakable tube holders 12 LIMITED efficiency: for large volume adapters INEFFICIENT cooling option: dry ice rack only the bottom of the tube is in the ice Lysing kits Technology Features 16 lysing kits + Extraction kits 3D bead-beating NOT USER-FRIENDLY: screw locking system + no handle for the lid NEW = IHM touch screen + 60 saved programs + USB exports Speed 4m/s to 10m/s Throughput 2mL x 24 2mL x 48 15mL x 12 Volume 50mL x 2 Cooling option Yes, dry ice Price List / $ 10,989

13 FASTPREP24 - MP BIOMEDICAL, USA POOR quality: 100% plastic + hole between operating area and mechanical part 13 LIMITED efficiency: due to small speed range INEFFICIENT large volume adapters: decrease beadbeating efficiency INEFFICIENT cooling option: dry ice rack only the bottom of the tube is in the ice Convert FastPrep protocol in Precellys: equivalence available on request *Equivalence with Precellys speed Lysing kits Technology Features 10 lysing kits Extraction kits 3D bead-beating Speed rpm * Throughput Volume Cooling option 2mL x 24 2mL x 48 15mL x 12 50mL x 2 Yes, dry ice Price list 8500 / $10,000 Bottom offer 6500 / $8,500

14 14

15 LYSING KITS OFFER - PRECELLYS VS FASTPREP 15 PRECELLYS FASTPREP V 0.5mL 2mL 2mL-R 7mL 15mL 2mL 4,5mL 15mL 50mL Reinforced tubes 121 C - 80 C Large temperature range + Do it yourself solution tubes and beads 15 C 30 C Do it yourself solution tubes and beads Each bead mix is unique Easy to choose the appropriate kit Very similar bead mixes Difficult to choose

16 TISSUE LYSER II - QIAGEN, NL 16 INEFFICIENT 1D motion ONY LOW speeds available NO prefilled tubes NO program LIMITED speed range Lysing kits Technology Features Only beads 1D bead-beating Speed rpm * Sold with extraction kit INEFFICIENT cooling accessory Throughput 2mL x 24 Volume 5mL x well tube strip: 25µL, 0.9mL Cooling option Yes Price List 5709 / $6500 Bottom Offer 4500 / $6500 *Equivalence with Precellys speed

17 BEADRUPTOR24 - OMNI INTERNATIONAL, USA 17 DIFFICULT to load the tubes: Screw system / Vertical axis INEFFICIENT in grinding large volumes EXPENSIVE adapters : 7ml = $1,495 / and 30ml = $1,695 / and expensive 30ml tubes = 7 -$/tube POOR scientific support DIFFICULT to manage 99 programs without advanced interface USELESS access to low speed (<3000rpm) No delay between runs old argument of Bead Ruptor to fight Precellys Lysing kits Technology Features 10 lysing kits (purchase from MoBio) 3D bead-beating Speed rpm * Throughput Volume Cooling option 2mL x 24 (or 0.5mL) 7mL x 12 30mL x 6 96 well tube strip: 25µL, 0.9mL Yes = poor copy of the Cryolys and difficult to monitor airflow with gauge ~5400 Price list / $9,250 Bottom Offer 7800 *Equivalence with Precellys speed

18 BEADRUPTOR12 - OMNI INTERNATIONAL, USA 18 NEED TO BALANCE THE TUBE HOLDER: Put at least 4 tubes of 2mL ONLY THREE SPEEDS AVAILABLE NOT CE CERTIFIED INEFFICIENT GRINDING when processing 2mL and 7mL at the same time NOT USER FRIENDLY locking system Lysing kits Technology Speed Throughput Volume Features 10 lysing kits (purchase from MoBio) 3D bead-beating 3m/S 4m/s 5m/s 12 x 2mL (or 0.5mL) 4 x 7mL No delay between runs old argument of Beadruptor Precellys does it now! Cooling option Yes = poor copy of the Cryolys and difficult to monitor airflow with gauge ~5400 Price List 5000 / $4,950 *Equivalence with Precellys speed

19 COMPETITOR COMPARISON Features Precellys Evolution Fast Prep 5G Omni Bead Ruptor Quiagen TissueLyser II 19 Flexibility 4 sizes 4 sizes 2 sizes 2 sizes Efficiency on hard samples Reproducibility Yes for each size and each sample Depending on size and sample Depending on size and sample Depending on size and sample Safe Automatic alarms Panic button Heat generation Low Medium High High Sensitive samples preservation Yes, Cryolys Inefficient option Copy of Cryolys no Lysing matrix >25 + starter boxes User friendly interface memory Unlimited number of protocols

20 20 COMMERCIAL CLAIMS

21 PRECELLYS - DIFFERENTIATION Innovation for user-friendliness: Patented tube locking system for market leading simplicity - No screw caps or clips for sample securing 21 USB connection: import/export protocols 1 machine 4 volumes: 0.5mL, 2mL, 7mL and 15mL Innovation for Quality: designed for BSL3 lab Robustness: Metal parts quality manufacture in France (MTF: samples) User safety: lid locking eliminates lab hazards & tight proof separation between biological area and mechanics Consistency monitoring: Internal specification checks 21

22 PRECELLYS - DIFFERENTIATION Innovation for Efficiency: Patented cooling unit High speed 3D-movement 22 Innovation for Scientific Support: Ready to answer: Application specialists dedicated to protocol optimization 24h support: Application center more than 2500 application notes protocols and publications

23 HOW TO LOCK UP A TENDER? Focus on differentiation features: 23 Tube blocking system: Vacuum force no screw Operational speed range: 4500 to rpm Safety: Lid, speed, temperature and pressure alarms Metal parts & hermetic separation between mechanical (and electronic) part from operating area Robustness MTF: samples Design for BSL3 lab IHM: easy to use Unlimited number of programs

24 24 AVAILABLE TOOLS Online or on request

25 MARKETING TOOLS Connect to the distributor resources and download all the marketing tools 25 For further information, please contact:

26 TOOLS UPON REQUEST 26 Recurrent update information Thanks to your feedback Specific documents Commercial support Protocol comparison Specific application question

27 27 CURRENT PROMOTIONS Further help!

28 VALID UNTIL DEC For each ordered Precellys24, Dual and Cryolys before the end of Get 10% off! Terms and conditions 1. Mention " STAR FINAL (Q4) " in your order / 2. Discounts is calculated on distributor prices / 3. Offer valid until December 31 st 2014 / 6. For any details, contact your Sales Area Manager / 7. Cannot be cumulated with other discounts

29 For each ordered Precellys Evolution before the end of the year Get 5% off! + Get 1 additional FREE holder pack! + Get 2 nd additional holder pack with 50% off! + Get 1 free kit! VALID UNTIL DEC Terms and conditions 1. Mention " STAR OF1" in your order / 2. Discounts are calculated on distributor price / 3. Offer valid from Sept 18 th to Dec 31 st 2014 / 4. 1 holder pack is defined as 1 blocking plate + 1 tubes holder / 5. kit means: any prefilled tube indicated in your price list (0.5mL, 2mL, 7mL or 15mL) / 6. Cannot be applied with other promotion / 7. For any details, contact your Sales

30 VALID UNTIL DEC *Terms and conditions 1. Mention " STAR 4FOR3" in your order / 2. Offer valid from September 18 th to December 31 st warranty forms signed by customers to be presented or proof of online registration / 4. Offer usable once / 5. Include the 4th free unit in your next order containing other items / 6. For any detail, contact your Sales Area Manager.

31 CONCLUSIONS Precellys key arguments

32 PRECELLYS UNIQUENESS High Quality 32 Efficiency Ergonomics

33 33 THANK YOU FOR YOUR ATTENTION Feel free to ask any question with chat box?

34 THANK YOU FOR YOUR ATTENTION 1) Use the questions tab if you have questions or remarks. 34 2) Please take 2 minutes to fill out the survey (only 5 questions) to continue the improvement of our next webinar and help us to define the next subjects. 3) The presentation will be put online on the Precellys Distributor Resources next week. 1) and keep sharing your competition information with us everyday!

35 BEADBEATING COMPETITION MAP 35 Application Center more than scientific documents Designed for BSL3 60,000 samples MTF Patented and efficient system Volume & samples Patented locking system