Version 2 Revision Date Print Date GB / EN SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING

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1 SAFETY DATA SHEET according to Regulation (EC) No. 1907/2006 SODIUM THIOCYANATE SECTION 1: IDENTIFICATION OF THE SUBSTANCE/MIXTURE AND OF THE COMPANY/UNDERTAKING 1.1 Product identifier Trade name : SODIUM THIOCYANATE Index-No. : REACH Registration Number : Relevant identified uses of the substance or mixture and uses advised against Use of the Substance/Mixture : Specific use(s): Use in synthesis and as intermediate. Use in spraying formulations. Building and construction work Laboratory activities Specific use(s): Refer to attached exposure scenario Annex. 1.3 Details of the supplier of the safety data sheet Company : Carbosulf Chemische Werke GmbH Geestemünder Str.26 DE Köln Germany Telephone : Telefax : address : RegulatoryAffairs@akzonobel.com 1.4 Emergency telephone number Emergency telephone number SECTION 2: HAZARDS IDENTIFICATION 2.1 Classification of the substance or mixture : 24 hours: Classification (REGULATION (EC) No 1272/2008) 1/107

2 Acute toxicity, 4, H302 Acute toxicity, 4, H332 Acute toxicity, 4, H312 Serious eye damage, 1, H318 Chronic aquatic toxicity, 3, H412 For the full text of the H-Statements mentioned in this Section, see Section Label elements Labelling (REGULATION (EC) No 1272/2008) Pictogram : Signal word Hazard statements Precautionary statements : Danger : H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled H318 Causes serious eye damage. H412 Harmful to aquatic life with long lasting effects. : Prevention: P261 Avoid breathing dust or fume. P264 Wash skin thoroughly after handling. P273 Avoid release to the environment. P280 Wear protective gloves/ eye protection/ face protection. Response: P305 + P351 + P338 + P310 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER/doctor. Disposal: P501 Dispose of contents/container in accordance with local regulation. Hazardous components which must be listed on the label: Thiocyanic acid, sodium salt Additional Labelling: EUH032 Contact with acids liberates very toxic gas. 2.3 Other hazards No further data available. PBT and vpvb assessment : This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or 2 / 107

3 very persistent and very bioaccumulative (vpvb) at levels of 0.1% or higher. 3 / 107

4 SECTION 3: COMPOSITION/INFORMATION ON INGREDIENTS 3.1 Substances Hazardous substance Chemical name PBT vpvb OEL CAS-No. EC-No. REACH No. Classification (REGULATION (EC) No 1272/2008) Concentration [%] Thiocyanic acid, sodium salt Acute Tox. 4; H302 Acute Tox. 4; H332 Acute Tox. 4; H312 Eye Dam. 1; H318 Aquatic Chronic 3; H For the full text of the H-Statements mentioned in this Section, see Section 16. REACH - Candidate List of Substances of Very High Concern for Authorisation (Article 59). Status : Not applicable SECTION 4: FIRST AID MEASURES 4.1 Description of first aid measures General advice If inhaled In case of skin contact In case of eye contact If swallowed : Immediate medical attention is required. Move out of dangerous area. Show this safety data sheet to the doctor in attendance. : Remove to fresh air. Keep patient warm and at rest. Rinse nose and mouth with water. : Take off contaminated clothing and shoes immediately. If skin irritation persists, call a physician. : Rinse with plenty of water. Get medical attention immediately. Continue to rinse during transport. Remove contact lenses. Protect unharmed eye. Keep eye wide open while rinsing. : Clean mouth with water and drink afterwards plenty of water. Never give anything by mouth to an unconscious person. Obtain medical attention. 4.2 Most important symptoms and effects, both acute and delayed Symptoms : The symptoms and effects are as expected from the hazards as shown in section 2. No specific product related symptoms 4 / 107

5 are known. Risks : Harmful if swallowed, in contact with skin or if inhaled Causes serious eye damage. 4.3 Indication of any immediate medical attention and special treatment needed Treatment : Treat symptomatically. SECTION 5: FIREFIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media 5.2 Special hazards arising from the substance or mixture Specific hazards during firefighting / Specific hazards arising from the chemical : Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. : Do not allow run-off from fire fighting to enter drains or water courses. Heating may cause decomposition with release of toxic fumes. Combustion products : Fire will produce smoke containing hazardous combustion products (see section 10). 5.3 Advice for firefighters Special protective equipment for firefighters Further information : In the event of fire, wear self-contained breathing apparatus. : Collect contaminated fire extinguishing water separately. This must not be discharged into drains. Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations. SECTION 6: ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Personal precautions : Use personal protective equipment. Wear respiratory protection. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation. 6.2 Environmental precautions Environmental precautions : Try to prevent the material from entering drains or water courses. If the product contaminates rivers and lakes or drains inform respective authorities. 6.3 Methods and materials for containment and cleaning up Methods for cleaning up / Methods for containment : Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal. 5 / 107

6 6.4 Reference to other sections Additional advice : For personal protection see section 8. SECTION 7: HANDLING AND STORAGE 7.1 Precautions for safe handling Advice on safe handling : For personal protection see section 8. Avoid formation of respirable particles. Do not breathe vapours/dust. Avoid contact with skin, eyes and clothing. Smoking, eating and drinking should be prohibited in the application area. Provide sufficient air exchange and/or exhaust in work rooms. Dispose of rinse water in accordance with local and national regulations. Keep away from heat and sources of ignition. Advice on protection against fire and explosion : Provide appropriate exhaust ventilation at places where dust is formed. 7.2 Conditions for safe storage, including any incompatibilities Requirements for storage areas and containers Advice on common storage Other data : Keep in a dry place. Store at room temperature in the original container. Keep container tightly closed. : Do not store near acids. : No decomposition if stored and applied as directed. 7.3 Specific end use(s) Specific use(s) : Refer to attached exposure scenario Annex. SECTION 8: EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control parameters Components with workplace control parameters Contains no substances with occupational exposure limit values. Derived No Effect Level (DNEL) according to Regulation (EC) No. 1907/2006 Substance name End Use routes Potential health effects Value Thiocyanic acid, sodium salt Workers Inhalation Long-term systemic effects Workers Skin contact Long-term systemic effects 3 mg/m3 1.7 mg/kg bw /day Consumers Inhalation Long-term systemic 1.1 mg/m3 6 / 107

7 effects Consumers Skin contact Long-term systemic effects Consumers Ingestion Long-term systemic effects 1.2 mg/kg bw /day 0.3 mg/kg bw /day Predicted No Effect Concentration (PNEC) according to Regulation (EC) No. 1907/2006 Substance name Environmental Compartment Value Thiocyanic acid, sodium salt Fresh w ater mg/l Marine w ater mg/l Intermittent w ater Sew age treatment plant Fresh w ater sediment Marine sediment Soil Secondary Poisoning mg/l 30 mg/l mg/kg dry w eight mg/kg dry w eight mg/kg dry w eight mg/kg food 8.2 controls Engineering controls Provide appropriate exhaust ventilation at places where dust is formed. Ensure that eyewash stations and safety showers are close to the workstation location. Personal protective equipment Respiratory protection : Half mask with a particle filter P2 (EN 143) Hand protection : For prolonged or repeated contact use protective gloves. Protective gloves complying with EN 374. Eye protection Skin and body protection Hygiene measures : Tightly fitting safety goggles : Protective suit : Handle in accordance with good industrial hygiene and safety practice. When using do not eat or drink. When using do not smoke. Wash hands before breaks and at the end of workday. Environmental exposure controls General advice : Try to prevent the material from entering drains or water courses. If the product contaminates rivers and lakes or drains inform respective authorities. SECTION 9: PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information on basic physical and chemical properties 7 / 107

8 Appearance Form Colour Odour Odour Threshold : crystalline : white : odourless : No data available Safety data ph : 5-9 at 5 % solution (as aqueous solution) Melting point : 308 C Boiling point/boiling range Flash point Evaporation rate Flammability (solid, gas) Flammability (liquids) Lower explosion limit Upper explosion limit Vapour pressure Relative vapour density : Not relevant. : Not applicable : Not applicable : Not flammable : Not applicable : Not applicable : Not applicable : Not applicable : Not applicable Relative density : Bulk density : kg/m3 Water solubility : 1,250 g/l at 20 C Solubility in other solvents Partition coefficient: n- octanol/water Auto-ignition temperature : Soluble in:, Acetone, Methanol, Ethanol : log Pow: estimated : Not applicable Decomposition temperature : > 368 C Viscosity, dynamic Viscosity, kinematic Explosive properties : Not applicable : Not applicable : Not explosive 8 / 107

9 Oxidizing properties : Not relevant. 9.2 Other information This safety datasheet only contains information relating to safety and does not replace any product information or product specification. SECTION 10: STABILITY AND REACTIVITY 10.1 Reactivity Stable under normal conditions Chemical stability Stable under recommended storage conditions Possibility of hazardous reactions Contact with acids liberates very toxic gas. Decomposition products may be flammable Conditions to avoid Conditions to avoid : None known Incompatible materials Materials to avoid : Incompatible with strong acids and oxidizing agents Hazardous decomposition products Hazardous decomposition products : Carbon disulphide Sodium oxide nitrogen oxides (NOx) Carbonyl sulfide Sulphur oxides Thermal decomposition : > 368 C SECTION 11: TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Product information: Acute toxicity : Harmful if swallowed, in contact with skin or if inhaled Skin corrosion/irritation : Not classified based on available information. Serious eye damage/eye irritation Respiratory or skin sensitisation : Causes serious eye damage. : Respiratory sensitisation: Not classified based on available information. Skin sensitisation: Not classified based on available information. Germ cell mutagenicity : Not classified based on available information. 9 / 107

10 Carcinogenicity : Not classified based on available information. Reproductive toxicity : Not classified based on available information. STOT - single exposure : Not classified based on available information. STOT - repeated exposure : Not classified based on available information. Aspiration hazard : Not classified based on available information. Further information : No further data available. Test result Acute oral toxicity Acute toxicity Acute toxicity : Acute toxicity estimate: mg/kg Method: Calculation method : Acute toxicity estimate : 1.52 mg/l time: 4 h Test atmosphere: dust/mist Method: Calculation method : Acute toxicity estimate: 1,112 mg/kg Method: Calculation method Toxicology data for the components: Thiocyanic acid, sodium salt Acute toxicity: Acute oral toxicity : LD50: 541 mg/kg Species: Coturnix japonica (Japanese quail) Method: OECD Test Guideline 401 Read-across from supporting substance (structural analogue or surrogate). Acute toxicity Acute toxicity Skin corrosion/irritation Serious eye damage/eye irritation Respiratory or skin sensitisation Repeated dose toxicity : No data available : LD50: > 2,000 mg/kg Species: Rat Method: OECD Test Guideline 402 Read-across (Analogy) : Result: No skin irritation : Species: Rabbit Result: Risk of serious damage to eyes. : Species: Mouse Classification: Does not cause skin sensitisation. Method: OECD Test Guideline 429 : Species: Rat Application Route: Oral NOEL: 21.3 mg/kg 10 / 107

11 Germ cell mutagenicity Read-across (Analogy) Genotoxicity in vitro : In vitro gene mutation study in mammalian cells mouse lymphoma cells Result: negative Method: OECD Test Guideline 476 Ames test Result: negative Method: OECD Test Guideline 471 Read-across from supporting substance (structural analogue or surrogate). Chromosome aberration test in vitro Human lymphocytes Result: negative Method: OECD Test Guideline 473 Genotoxicity in vivo : Not classified due to data which are conclusive although insufficient for classification. Carcinogenicity : Reproductive toxicity : study scientifically unjustified Based on available data, the classification criteria are not met. STOT - single exposure STOT - repeated exposure Aspiration hazard : Not classified due to data which are conclusive although insufficient for classification. : Not classified due to data which are conclusive although insufficient for classification. : Not classified due to data which are conclusive although insufficient for classification. SECTION 12: ECOLOGICAL INFORMATION Product information: Ecotoxicology Assessment Additional ecological information : An environmental hazard cannot be excluded in the event of unprofessional handling or disposal. Toxic to aquatic life. Harmful to aquatic life with long lasting effects Toxicity Components: Test result Thiocyanic acid, sodium salt Toxicity to fish : LC50: 69 mg/l 11 / 107

12 time: 96 h Species: Oncorhynchus mykiss (rainbow trout) Test Type: static test Method: OECD Test Guideline 203 Read-across from supporting substance (structural analogue or surrogate). Toxicity to daphnia and other aquatic invertebrates Toxicity to algae : EC50: 3.79 mg/l time: 48 h Species: Daphnia magna (Water flea) Test Type: static test Method: OECD Test Guideline 202 Read-across from supporting substance (structural analogue or surrogate). : EC10: mg/l time: 72 h Species: Pseudokirchneriella subcapitata (green algae) Test Type: Growth inhibition Method: OECD Test Guideline 201 Read-across from supporting substance (structural analogue or surrogate). ErC50: > mg/l time: 72 h Species: Pseudokirchneriella subcapitata (green algae) Test Type: Growth inhibition Method: OECD Test Guideline 201 Read-across from supporting substance (structural analogue or surrogate). Toxicity to bacteria : NOEC: 2.13 mg/l time: 28 d Test Type: static test Method: closed serum bottle Read-across from supporting substance (structural analogue or surrogate). NOEC: 30 mg/l time: 12 h Test Type: static test Read-across from supporting substance (structural analogue or surrogate). Toxicity to fish (Chronic toxicity) Toxicity to daphnia and other aquatic invertebrates (Chronic toxicity) : NOEC: 1.53 mg/l time: 124 d Species: Pimephales promelas (fathead minnow) Read-across from supporting substance (structural analogue or surrogate). : NOEC: 1.33 mg/l time: 21 d reproduction rate 12 / 107

13 Species: Daphnia magna (Water flea) Method: OECD Test Guideline 211 Read-across from supporting substance (structural analogue or surrogate) Persistence and degradability Product information: Biodegradability Components: Thiocyanic acid, sodium salt Biodegradability : Result: Readily biodegradable : Result: Readily biodegradable Method: Closed Bottle test 12.3 Bioaccumulative potential Product information: Bioaccumulation Components: Thiocyanic acid, sodium salt Bioaccumulation : Not expected considering the low log Pow value. : Not expected considering the low log Pow value Mobility in soil Product information: Mobility : No data available Components 12.5 Results of PBT and vpvb assessment Product information: PBT and vpvb assessment Components: Thiocyanic acid, sodium salt PBT and vpvb assessment 12.6 Other adverse effects Product information: Biochemical Oxygen Demand (BOD) Components: Thiocyanic acid, sodium salt Biochemical Oxygen Demand (BOD) : No information available. : This substance/mixture contains no components considered to be either persistent, bioaccumulative and toxic (PBT), or very persistent and very bioaccumulative (vpvb) at levels of 0.1% or higher. : This substance is not considered to be a PBT (Persistent, Bioaccumulation, Toxic) This substance is not considered to be vpvb (very Persistent nor very Bioaccumulating) : No data available : No data available 13 / 107

14 SECTION 13: DISPOSAL CONSIDERATIONS 13.1 Waste treatment methods Product Contaminated packaging : The product should not be allowed to enter drains, water courses or the soil. Do not contaminate ponds, waterways or ditches with chemical or used container. Hazardous waste Dispose of contents/container in accordance with local regulation. : Empty remaining contents. Dispose of as unused product. SECTION 14: TRANSPORT INFORMATION 14.1 UN number Not regulated as a dangerous good 14.2 Proper shipping name Not regulated as a dangerous good 14.3 Transport hazard class Not regulated as a dangerous good 14.4 Packing group Not regulated as a dangerous good 14.5 Environmental hazards Not regulated as a dangerous good 14.6 Special precautions for user Remarks : Not classified as dangerous in the meaning of transport regulations Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code Not applicable for product as supplied. SECTION 15: REGULATORY INFORMATION 15.1 Safety, health and environmental regulations/legislation specific for the substance or mixture Major Accident Hazard Legislation : Seveso Directive 2012/18/EU Not applicable Water contaminating class (Germany) : WGK 1 slightly water endangering Notification status 14 / 107

15 TSCA DSL AICS NZIoC ENCS ISHL KECI PICCS IECSC : YES. All chemical substances in this product are either listed on the TSCA Inventory or in compliance with a TSCA Inventory exemption. : YES. All components of this product are on the Canadian DSL : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory : YES. On the inventory, or in compliance with the inventory For explanation of abbreviation see section 16. Further information This product is to be considered as a substance according to EU-legislation Chemical safety assessment Thiocyanic acid, sodium salt : A Chemical Safety Assessment has been carried out for this substance. SECTION 16: OTHER INFORMATION Full text of H-Statements referred to under sections 2 and 3. H302 H312 H318 H332 H412 Classification procedure: Acute toxicity, 4, H302, Calculation method Acute toxicity, 4, H332, Calculation method Acute toxicity, 4, H312, Calculation method Serious eye damage, 1, H318, Calculation method Chronic aquatic toxicity, 3, H412, Calculation method Full text of other abbreviations : Harmful if swallowed. : Harmful in contact with skin. : Causes serious eye damage. : Harmful if inhaled. : Harmful to aquatic life with long lasting effects. ADN - European Agreement concerning the International Carriage of Dangerous Goods by Inland Waterways; ADR - European Agreement concerning the International Carriage of Dangerous Goods by Road; AICS - Australian Inventory of Chemical Substances; ASTM - American Society for the Testing of Materials; bw - Body weight; CLP - Classification Labelling Packaging Regulation; Regulation (EC) No 1272/2008; CMR - Carcinogen, Mutagen or Reproductive Toxicant; DIN - Standard of the German Institute for Standardisation; DSL - Domestic Substances List (Canada); ECHA - European Chemicals Agency; EC-Number - European Community number; ECx - Concentration associated with x% response; ELx - Loading rate associated with x% response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan); ErCx - Concentration associated with x% growth rate response; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC - International Agency for Research on Cancer; IATA - International Air Transport Association; IBC - International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International Maritime Dangerous Goods; IMO - 15 / 107

16 International Maritime Organization; ISHL - Industrial Safety and Health Law (Japan); ISO - International Organisation for Standardization; KECI - Korea Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 - Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed (Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NZIoC - New Zealand Inventory of Chemicals; OECD - Organization for Economic Co-operation and Development; OPPTS - Office of Chemical Safety and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS - Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure Relationship; REACH - Regulation (EC) No 1907/2006 of the European Parliament and of the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals; RID - Regulations concerning the International Carriage of Dangerous Goods by Rail; SADT - Self- Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan Chemical Substance Inventory; TRGS - Technical Rule for Hazardous Substances; TSCA - Toxic Substances Control Act (United States); UN - United Nations; vpvb - Very Persistent and Very Bioaccumulative Further information The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. 16 / 107

17 Annex : Formulation & (re)packing of substances and mixtures, Dustiness: Low Formulation & (re)packing of substances and mixtures, Dustiness: Medium Formulation & (re)packing of substances and mixtures, Dustiness: High Industrial use, Use as an intermediate Industrial use, Spraying Industrial use, Processing aid, Dustiness: Low Industrial use, Processing aid, Dustiness: Medium Industrial use, Processing aid, Dustiness: High Professional use, Spraying 0. Professional use, Processing aid, Dustiness: Low 1. Professional use, Processing aid, Dustiness: Medium 2. Professional use, Processing aid, Dustiness: High 3. Industrial use, Building and construction work 4. Professional use, Building and construction work 5. Professional use, Used as laboratory reagent 17 / 107

18 1. Short title of Scenario: Formulation & (re)packing of substances and mixtures, Dustiness: Low Main User Groups Environmental Release Categories Process categories : SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites : ERC2: Formulation of preparations : PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at nondedicated facilities PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) PROC10: Roller application or brushing PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation PROC15: Use as laboratory reagent PROC19: Hand-mixing with intimate contact and only PPE available 2.1 Contributing scenario controlling environmental exposure for: ERC2: Formulation of preparations Amount used Regional use tonnage (tonnes/year): Fraction of EU tonnage used in region: Fraction of Regional tonnage used locally: Maximum daily site tonnage (kg/day): : ton(s)/year : 100 % : 0.2 % : 102 kg/day Environment factors not influenced by risk management Flow rate : 18,000 m3/day Dilution Factor (River) : / 107

19 Dilution Factor (Coastal Areas) : 100 Other given operational conditions affecting environmental exposure Number of emission days per : 300 year Emission or Release Factor: Air : 2.5 % Emission or Release Factor: : 2 % Water Emission or Release Factor: Soil : 0 % Conditions and measures related to municipal sewage treatment plant Type of Sewage Treatment Plant : Municipal sewage treatment plant Flow rate of sewage treatment : 2,000 m3/day plant effluent Percentage removed from waste : 0 % water 2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to all above mentioned process categories. Product characteristics Concentration of the Substance in Mixture/Article Physical Form (at time of use) Vapour pressure Frequency and duration of use Application duration Frequency of use : Industrial use : Covers the percentage of the substance in the product up to 100 % (unless stated differently). : Solid, low dustiness : < 0.01 Pa : <= 8 h : <= 365 days/year Other operational conditions affecting workers exposure Outdoor / Indoor : Indoor Organisational measures to prevent /limit releases, dispersion and exposure Assumes a good basic standard of occupational hygiene is implemented., Ensure operatives are trained to minimise exposures., Clean equipment and the work area every day., Clear spills immediately. Use suitable eye protection. 2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed process, no likelihood of exposure : General exposures (closed systems), Continuous process No specific measures identified., Handle substance within a closed system., Clear transfer 19 / 107

20 lines prior to de-coupling. 2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed, continuous process with occasional controlled exposure : General exposures (closed systems), Continuous process, Automated process with (semi) closed systems. No specific measures identified., Handle substance within a closed system., Clear transfer lines prior to de-coupling. 2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed batch process (synthesis or formulation) : General exposures, Use in contained batch processes No specific measures identified., Handle substance within a closed system., Drain down and flush system prior to equipment opening or maintenance. 2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises : General exposures, (open systems), Batch process When concentration is:, >5%, Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) : General exposures, Mixing operations (open systems), Batch process Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 20 / 107

21 2.8 Contributing scenario controlling worker exposure for: PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at non-dedicated facilities : General exposures, Non-dedicated facility, Material transfers Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 2.9 Contributing scenario controlling worker exposure for: PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities : General exposures, Dedicated facility, Material transfers When concentration is:, >5%, Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.10 Contributing scenario controlling worker exposure for: PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) : General exposures, Dedicated facility, Drum and small package filling, Material transfers When concentration is:, >5%, Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.11 Contributing scenario controlling worker exposure for: PROC10: Roller application or brushing : General exposures (open systems), Rolling, Brushing, Equipment cleaning and maintenance Organisational measures to prevent /limit releases, dispersion and exposure Limit the substance content in the product to 25 %. Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 21 / 107

22 2.12 Contributing scenario controlling worker exposure for: PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation : General exposures (open systems), Production or preparation or articles by tabletting, compression, extrusion or pelletisation When concentration is:, >5%, Wear suitable gloves tested to EN374. (Effectiveness (of a measure): 80 %) 2.13 Contributing scenario controlling worker exposure for: PROC15: Use as laboratory reagent : General exposures, Laboratory activities, small scale, Manual No specific measures identified Contributing scenario controlling worker exposure for: PROC19: Hand-mixing with intimate contact and only PPE available : General exposures, Mixing operations (open systems), Manual Organisational measures to prevent /limit releases, dispersion and exposure Limit the substance content in the product to 5 %. Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 3. estimation and reference to its source Environment Contributing Scenario Assessment Method Specific conditions 22 / 107 Compartme nt Value Level of ERC2 EUSES Fresh water mg/l EUSES Marine mg/l water RCR

23 EUSES Sewage 0.04 mg/l treatment plant EUSES Soil mg/kg dry weight Workers Contributing Scenario Assessment Method Specific conditions Value Level of PROC1 ECETOC TRA 0.01 mg/m mg/kg PROC2 ECETOC TRA 0.01 mg/m mg/kg PROC3 ECETOC TRA 0.1 mg/m mg/kg PROC4 ECETOC TRA 0.5 mg/m mg/kg PROC5 ECETOC TRA 0.5 mg/m mg/kg PROC8a ECETOC TRA 0.5 mg/m mg/kg PROC8b ECETOC TRA 0.1 mg/m mg/kg PROC9 ECETOC TRA 0.1 mg/m mg/kg PROC10 ECETOC TRA 0.3 mg/m mg/kg PROC14 ECETOC TRA 0.1 mg/m mg/kg PROC15 ECETOC TRA 0.1 mg/m / 107 RCR

24 PROC19 ECETOC TRA 0.34 mg/kg mg/m mg/kg ERC2: Formulation of preparations PROC1: Use in closed process, no likelihood of exposure PROC10: Roller application or brushing PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation PROC15: Use as laboratory reagent PROC19: Hand-mixing with intimate contact and only PPE available PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) 4. Guidance to Downstream User to evaluate whether he works inside the boundaries set by the Scenario Guidance is based on assumed operating conditions which may not be applicable to all sites; thus, scaling may be necessary to define appropriate site -specific risk. 24 / 107

25 1. Short title of Scenario: Formulation & (re)packing of substances and mixtures, Dustiness: Medium Main User Groups Environmental Release Categories Process categories : SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites : ERC2: Formulation of preparations : PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at nondedicated facilities PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation PROC15: Use as laboratory reagent PROC19: Hand-mixing with intimate contact and only PPE available 2.1 Contributing scenario controlling environmental exposure for: ERC2: Formulation of preparations Amount used Regional use tonnage (tonnes/year): Fraction of EU tonnage used in region: Fraction of Regional tonnage used locally: Maximum daily site tonnage (kg/day): : ton(s)/year : 100 % : 0.2 % : 102 kg/day Environment factors not influenced by risk management Flow rate : 18,000 m3/day Dilution Factor (River) : 10 Dilution Factor (Coastal Areas) : / 107

26 Other given operational conditions affecting environmental exposure Number of emission days per : 300 year Emission or Release Factor: Air : 2.5 % Emission or Release Factor: : 2 % Water Emission or Release Factor: Soil : 0 % Conditions and measures related to municipal sewage treatment plant Type of Sewage Treatment Plant : Municipal sewage treatment plant Flow rate of sewage treatment : 2,000 m3/day plant effluent Percentage removed from waste : 0 % water 2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to all above mentioned process categories. Product characteristics Concentration of the Substance in Mixture/Article Physical Form (at time of use) Vapour pressure Frequency and duration of use Application duration Frequency of use : Covers the percentage of the substance in the product up to 100 % (unless stated differently). : Solid, medium dustiness : < Pa : <= 8 h : <= 365 days/year Other operational conditions affecting workers exposure Outdoor / Indoor : Indoor Organisational measures to prevent /limit releases, dispersion and exposure Assumes a good basic standard of occupational hygiene is implemented., Ensure operatives are trained to minimise exposures., Clean equipment and the work area every day., Clear spills immediately. Use suitable eye protection. Additional good practice advice beyond the REACH Chemical Safety Assessment Additional good practice advice : Respirators: - Wear a disposable mask only once - Clean non-disposable masks after each use and store in a clean box in a clean area - Wear respirators 2 hrs/day,avoid carrying out operation for more than 4 hours. 2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed process, no likelihood of exposure 26 / 107

27 : General exposures (closed systems), Continuous process No specific measures identified., Handle substance within a closed system., Clear transfer lines prior to de-coupling. 2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed, continuous process with occasional controlled exposure : General exposures (closed systems), Continuous process, Automated process with (semi) closed systems. Wear suitable gloves tested to EN374. (Effectiveness (of a measure): 80 %) 2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed batch process (synthesis or formulation) : General exposures, Use in contained batch processes No specific measures identified., Handle substance within a closed system., Drain down and flush system prior to equipment opening or maintenance. 2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises : General exposures, Batch process, (open systems) When concentration is:, >5%, Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) : General exposures, Mixing operations (open systems), 27 / 107

28 Batch process When concentration is:, >5%, Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.8 Contributing scenario controlling worker exposure for: PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at non-dedicated facilities : General exposures, Material transfers, Non-dedicated facility When concentration is:, >5%, Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.9 Contributing scenario controlling worker exposure for: PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities : General exposures, Material transfers, Dedicated facility When concentration is:, >5%, Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.10 Contributing scenario controlling worker exposure for: PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) 28 / 107

29 : Drum and small package filling, General exposures, Material transfers, Dedicated facility When concentration is:, >5%, Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.11 Contributing scenario controlling worker exposure for: PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation : General exposures (open systems), Production or preparation or articles by tabletting, compression, extrusion or pelletisation When concentration is:, >5%, Wear suitable gloves tested to EN374. (Effectiveness (of a measure): 80 %) 2.13 Contributing scenario controlling worker exposure for: PROC15: Use as laboratory reagent : General exposures, Laboratory activities, small scale, Manual No specific measures identified Contributing scenario controlling worker exposure for: PROC19: Hand-mixing with intimate contact and only PPE available : General exposures, Mixing operations (open systems), Manual Organisational measures to prevent /limit releases, dispersion and exposure Avoid carrying out operation for more than 1 hour., Limit the substance content in the product to 5 %. Wear chemically resistant gloves (tested to EN374) in combination with specific activity 29 / 107

30 training. (Effectiveness (of a measure): 95 %) Wear a respirator conforming to EN140 with Type A/P2 filter or better. (Effectiveness (of a measure): 90 %) 3. estimation and reference to its source Environment Contributing Scenario Assessment Method Specific conditions Compartme nt Value Level of ERC2 EUSES Fresh water mg/l EUSES Marine mg/l water EUSES Sewage 0.04 mg/l treatment plant EUSES Soil mg/kg dry weight RCR Workers Contributing Scenario Assessment Method Specific conditions Value Level of PROC1 ECETOC TRA 0.01 mg/m mg/kg PROC2 ECETOC TRA 0.5 mg/m mg/kg PROC3 ECETOC TRA 1 mg/m mg/kg PROC4 ECETOC TRA 0.5 mg/m mg/kg PROC5 ECETOC TRA 0.5 mg/m mg/kg PROC8a ECETOC TRA 0.5 mg/m mg/kg PROC8b ECETOC TRA 1 mg/m / 107 RCR

31 PROC9 ECETOC TRA PROC14 ECETOC TRA PROC15 ECETOC TRA PROC19 ECETOC TRA 0.69 mg/kg mg/m mg/kg mg/m mg/kg mg/m mg/kg mg/m mg/kg ERC2: Formulation of preparations PROC1: Use in closed process, no likelihood of exposure PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation PROC15: Use as laboratory reagent PROC19: Hand-mixing with intimate contact and only PPE available PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at non-dedicated facilities PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) 4. Guidance to Downstream User to evaluate whether he works inside the boundaries set by the Scenario Guidance is based on assumed operating conditions which may not be applicable to all sites; thus, scaling may be necessary to define appropriate site -specific risk. 31 / 107

32 1. Short title of Scenario: Formulation & (re)packing of substances and mixtures, Dustiness: High Main User Groups Environmental Release Categories Process categories : SU 3: Industrial uses: Uses of substances as such or in preparations at industrial sites : ERC2: Formulation of preparations : PROC1: Use in closed process, no likelihood of exposure PROC2: Use in closed, continuous process with occasional controlled exposure PROC3: Use in closed batch process (synthesis or formulation) PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at nondedicated facilities PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) PROC14: Production of preparations or articles by tabletting, compression, extrusion, pelletisation PROC15: Use as laboratory reagent PROC19: Hand-mixing with intimate contact and only PPE available 2.1 Contributing scenario controlling environmental exposure for: ERC2: Formulation of preparations Amount used Regional use tonnage (tonnes/year): Fraction of EU tonnage used in region: Fraction of Regional tonnage used locally: Maximum daily site tonnage (kg/day): : ton(s)/year : 100 % : 0.2 % : 102 kg/day Environment factors not influenced by risk management Flow rate : 18,000 m3/day Dilution Factor (River) : 10 Dilution Factor (Coastal Areas) : / 107

33 Other given operational conditions affecting environmental exposure Number of emission days per : 300 year Emission or Release Factor: Air : 2.5 % Emission or Release Factor: : 2 % Water Emission or Release Factor: Soil : 0 % Conditions and measures related to municipal sewage treatment plant Type of Sewage Treatment Plant : Municipal sewage treatment plant Flow rate of sewage treatment : 2,000 m3/day plant effluent Percentage removed from waste : 0 % water 2.2 Contributing scenario controlling worker exposure for: All PROCs: Applicable to all above mentioned process categories. Product characteristics Concentration of the Substance in Mixture/Article Physical Form (at time of use) Vapour pressure Frequency and duration of use Application duration Frequency of use : Covers the percentage of the substance in the product up to 25 %. : Solid, high dustiness : < Pa : <= 8 h : <= 365 days/year Other operational conditions affecting workers exposure Outdoor / Indoor : Indoor Organisational measures to prevent /limit releases, dispersion and exposure Assumes a good basic standard of occupational hygiene is implemented., Ensure operatives are trained to minimise exposures., Clean equipment and the work area every day., Clear spills immediately. Use suitable eye protection. 2.3 Contributing scenario controlling worker exposure for: PROC1: Use in closed process, no likelihood of exposure : General exposures (closed systems), Continuous process No specific measures identified., Handle substance within a closed system., Clear transfer lines prior to de-coupling. 33 / 107

34 2.4 Contributing scenario controlling worker exposure for: PROC2: Use in closed, continuous process with occasional controlled exposure : General exposures (closed systems), Continuous process, Automated process with (semi) closed systems. Wear suitable gloves tested to EN374. (Effectiveness (of a measure): 80 %) 2.5 Contributing scenario controlling worker exposure for: PROC3: Use in closed batch process (synthesis or formulation) : General exposures, Use in contained batch processes No specific measures identified., Handle substance within a closed system., Drain down and flush system prior to equipment opening or maintenance. 2.6 Contributing scenario controlling worker exposure for: PROC4: Use in batch and other process (synthesis) where opportunity for exposure arises : General exposures, Batch process, (open systems) Provide extraction ventilation at points where emissions occur., Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.7 Contributing scenario controlling worker exposure for: PROC5: Mixing or blending in batch processes for formulation of preparations and articles (multistage and/ or significant contact) : General exposures, Mixing operations (open systems), Batch process Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) 34 / 107

35 Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 2.8 Contributing scenario controlling worker exposure for: PROC8a: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at non-dedicated facilities : General exposures, Non-dedicated facility, Material transfers Provide extraction ventilation at points where emissions occur., Ensure material transfers are under containment or extract ventilation. (Effectiveness (of a measure): 90 %) Organisational measures to prevent /limit releases, dispersion and exposure Avoid carrying out operation for more than 4 hours. Wear chemically resistant gloves (tested to EN374) in combination with specific activity training. (Effectiveness (of a measure): 95 %) 2.9 Contributing scenario controlling worker exposure for: PROC8b: Transfer of substance or preparation (charging/ discharging) from/ to vessels/ large containers at dedicated facilities : General exposures, Material transfers, Dedicated facility Ensure material transfers are under containment or extract ventilation., Provide extract ventilation to material transfer points and other openings. (Effectiveness (of a measure): 90 %) Wear chemically resistant gloves (tested to EN374) in combination with basic employee training. (Effectiveness (of a measure): 90 %) 2.10 Contributing scenario controlling worker exposure for: PROC9: Transfer of substance or preparation into small containers (dedicated filling line, including weighing) : General exposures, Dedicated facility, Drum and small package filling, Material transfers Provide extraction ventilation at points where emissions occur., Ensure material transfers are 35 / 107