The impact of industrial pollution on levels of contaminants in humans and locally harvested food in the Norwegian, Finnish and Russian border region

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1 The impact of industrial pollution on levels of contaminants in humans and locally harvested food in the Norwegian, Finnish and Russian border region Martine Dalgaard Hansen MSc Clinical Nutrition & BSc Nursing PhD student at The Department of Community Medicine The Arctic University of Norway - UiT

2 Background - Pollution Industrial pollution in the area mainly SO 2, Ni and Cu concentrations of heavy metals and dioxins in the local environment Puts the health of people resided in the area at potential risk

3 Background Local food Use of local food has historically been important Considered healthy with a high nutritional value Concern of contaminants might influence the use of these resources

4 Objectives Overall aim: Assess the impact of local pollution, mainly through local food, on the population in the Norwegian, Finnish and Russian border region Determine the concentrations of heavy metals (Co, Ni, Cu, Pb, As, Cd and Hg) and dioxins in local food in the Norwegian, Finnish and Russian border region Study the association between consumption of local food and plasma concentrations of heavy metals and dioxins in pregnant Norwegian, Finnish and Russian women Study the association between consumption of local food and plasma concentrations of heavy metals and dioxin in the general population of the municipality of Sør-Varanger Compare the use of local food in Sør-Varanger in 1994 and today New REK approval: Follow up - assess mortality from lung disease?

5 Material and Method Already sampled data from the Kolarctic project, the MISA cohort and the Norwegian-Russian Health Study 1994/95 Collection of new data Blood samples, questionnaires and possibly registry data

6 The Kolarctic project KO467 Aim: To assess the industrial impact on food safety and human health in the Norwegian, Finnish and Russian border region Material: Samples on berries, mushrooms, fish, reindeer and moose Data: Concentrations of cobalt (Co), nickel (Ni), copper (Cu), arsenic (As), cadmium (Cd), lead (Pb), mercury (Hg) and dioxins in food samples Data will be used to assess differences in concentrations between the different geographical location in relation to the industry on the Kola peninsula

7 The MISA cohort Design: Cross-sectional with longitudinal aspects Aim: To assess exposure to contaminant experienced by pregnant women and explore the association between levels of contaminants and health and pregnancy outcomes Material: 515 pregnant women from the counties of Finnmark, Troms and Nordland Data: Repeated blood samples and questionnaire data with detailed data on food intake between 2008 and 2009 Data will be used to study the association between intake of local food and plasma concentrations of heavy metals and dioxins in the women

8 The Norwegian-Russian Health Study 1994/95 Design: Cross-sectional population-based study. Aim: To map human exposures to local air pollution from the nickel industry on the Kola peninsula and investigate its possible health effects Material: 3671 residents of the municipality of Sør-Varanger aged participated in the Norwegian part of the study Data: Blood samples and questionnaire data with specific data on local food intake Data will be used to compare consumption of local food and concentrations of contaminants in humans in 1994 and today.

9 Collection of new data Design: Cross-sectional with aspects of following-up the Norwegian- Russian Health Study 1994/95 Material: All residents in the municipality of Sør-Varanger aged 18 (there are currently inhabitants in the municipality) Data: Questionnaire data and blood samples. Possibly registry data (death registries) The new data collected will be used to study the association between intake of local food and plasma concentrations of contaminants in the population, now and in 1994/95. Assess mortality from lung disease compared to a reference population

10 Questions?