[3-5] GC/MS LC/MS. Agilent 7890A/5975C GC/MS (DRS) GC/MS DRS

Transcription

1 : GC/MS Philip L. Wylie Agilent Technologies, Inc Centerville Rd. Wilmington, DE USA 2006 GC/MS LC/MS (DRS) 430 GC GC/MS (MHLW) [1,2] [3-5] 0.01 ppm GC 430 Agilent 7890A/5975C GC/MS GCMHLW DRS 430GC/MS 2

2 MHLW [6] GC/MS LC/MS GC/MS SIM DRS 1 LehotayQuEChERS [7 8] 1. Agilent 7890A Agilent J&W 30 m 0.25 mm 0.25 µm DB-5MS m 0.25mm Siltek [Restek Bellefonte PA USA 10026] 1.0 ml/min 5 m 0.25 mmgc1.1 ml/min 5 m 0.25 mmgcquickswap 1.7 ml/min 5.2 psi min 50 C (1 min) 25 C/min 125 C (0 min) 10 C/min 300 C (10 min) / 250 C Agilent 7683B 2 µl Agilent 5975C MSD u 0 70 ev n=2 280 C 3.5 min 230 C 150 C Atune.u GC/MS Agilent GC/MS G1701EA E G1716AA A NIST MS 2.0d NIST05 -Agilent G1033A AMDIS_ NIST05 G1033A NIST05 G1033A NIST G1675 AA 2

3 3 GC GC/MS GC/MS DRS 1 GC/MS2 (NIST) NIST053) NIST AMDIS DRS AMDIS NIST05 1 AMDIS AMDIS AMDIS 1. TIC TIC

4 NIST AMDIS DRS [11-17]DRS MHLWGC/MS [18] [19] 447 GC LC GC/MS [4] [5] MHLW GC/MS 59GC/MS 430 -d ng/g 18 DRSGC/MS 3 DRS ng/g8 7 DRS 4

5 DRS AMDIS AMDIS AMDIS AMDIS DRS 7DRS CAS DRS 100=AMDIS 6 1 DRS NIST05100 Hit number 4 DRS 5 MSD : : C:\msdchem\1\DATA\Strawberry_TID_2uL.D /: 04:44 PM Thursday, Sep NISTAMDIS AMDIS NIST R.T. Diff Reverse Hit Cas (ng/µl) Match sec. match number d d DRS 24 5

6 AMDIS NIST05 Q-edit DRS6 7 AMDIS 7a 7b 7c 4. C:\MSData\Sept 04_07 Lehotay samples using TID & Japanese method\mixed Fruit_TID_2uL.D 04:01 PM Monday, Sep NIST AMDIS NIST R.T. Diff Reverse Hit Cas (ng/µl) Match sec. match number d d

7 C:\MSData\Sept 04_07 Lehotay samples using TID & Japanese method\mixed Fruit_TID_2uL.D 04:11 PM Monday, Sep NIST AMDIS NIST R.T. Diff Reverse Hit Cas (ng/µl) Match sec. match number d d Q-Edit DRS [14,15]GC GC/MS 30 DRS 2GC a b c 7. AMDIS a) b) c 7

8 430 NIST AMDIS MHLW GC/MS DRS Introduction of the Positive List System for Agricultural Chemical Residues in Foods, Department of Food Safety, Ministry of Health, Labour and Welfare, June Positive List System for Agricultural Chemical Residues in Foods, Ministry of Health, Labour and Welfare 3. Maximum Residue Limits (MRLs) List of Agricultural Chemicals in Foods, The Japan Food Chemical Research Foundation foundation/search.html 4. Table in item 6 (1), Section A General Compositional Standards for Food, Part I Food: The maximum residue limits of substances used as ingredients of agricultural chemicals in foods 5. Table in item 7 (1), Section A General Compositional Standards for Food, Part I Food: The maximum residue limits of substances used as ingredients of agricultural chemicals in foods (Provisional MRLs List) 6. Analytical Methods for Residual Compositional Substances of Agricultural Chemicals, Feed Additives, and Veterinary Drugs in Food, Department of Food Safety, Ministry of Health, Labour and Welfare, 7. S. J. Lehotay, A. de Kok, M. Hiemstra, and P. van Bodegraven (2005) J. AOAC Int. 88, M. Anastassiades, S. Lehotay, D. ˇtajnbaher, and F. J. Schenck (2003) J. AOAC Int., 86, V. Giarocco, B. Quimby, and M. Klee, Retention Time Locking: Concepts and Applications, Agilent Technologies, publication E, H. Prest, P. Wylie, K. Weiner, and D. Agnew, Efficient Screening for Pesticides and Endocrine Disrupters Using the 6890/5973 GC/MSD System, Agilent Technologies, publication E, Philip L. Wylie, Screening for 926 Pesticides and Endocrine Disruptors by GC/MS with Deconvolution Reporting Software and a New Pesticide Library, Agilent Technologies, publication EN, Bruce Quimby, Screening for Hazardous Chemicals in Homeland Security and Environmental Samples Using a GC/MS/ECD/FPD with a 731 Compound DRS Database, Agilent Technologies, publication EN, Mike Szelewski and Bruce Quimby, New Tools for Rapid Pesticide Analysis in High Matrix Samples, Agilent Technologies, publication EN, Chris Sandy, A Blind Study of Pesticide Residues in Spiked and Unspiked Fruit Extracts Using Deconvolution Reporting Software, Agilent Technologies, publication EN, Philip Wylie, Michael Szelewski, Chin-Kai Meng, Christopher Sandy, Comprehensive Pesticide Screening by GC/MSD Using Deconvolution Reporting Software, Agilent Technologies, publication EN, 8

9 16. Xiaofei Ping, Chin-Kai Meng, Michael Szelewski, Building Agilent GC/MSD Deconvolution Reporting Libraries for Any Application, Agilent Technologies, publication EN, C. Lesueur and M. Gartner, Routine Identification and Quantification of Pesticide Multiresidues in Fruit and Vegetable Samples with Full Scan, SIM, and Deconvolution Reporting Software, Ernahrung/Nutrition 29 (11), (2005) 18. Y. Hirahara, et Al., Validation of Multiresidue Screening Methods for the Determination of 186 Pesticides in 11 Agricultural Products Using Gas Chromatography (GC), J. Health Science 51 (5) (2005) 19. Imported Foods Monitoring Plan for 2006 Notices Nos and , Office of Imported Food Safety, Ministry of Health, Labour and Welfare, May importedfoods/dl/4.pdf Steven Lehotay Katerina Mastovska 9

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