Products and accessories for blood banks

Transcription

1 Products and accessories for blood banks

2 PERFECT SOLUTIONS Focus on the user Our customers have been involved in the development process since the production of special blood bank centrifuges began decades ago. Ever since then, novel approaches have been continuously conceived, tested and implemented in association with our customers. As a result of this information acquisition and exchange we have developed high-performance products that have made everyday routines in blood banks and transfusion centres even more efficient and simpler. ROTO SILENTA 630 RS ROTO SILENTA 630 RS is a typical highquality centrifuge for blood bank use. It can achieve high RCF values (up to 6,520) thanks to its advanced rotor technology without a windshield. The comprehensive range of accessories caters for almost all applications, both standard and special ones. For example, blood bag insert 4529 is available for the preparation of thrombocyte concentrate or platelet rich plasma (PRP). It is suitable for all blood bag systems up to 500 ml. The blood bag can be suspended from hooks which are attached, in accordance with the customer s requirements, at one of 3 different heights on the insert. This allows the bag to be stabilized, regardless of its fill quantity, and prevents the accumulation of erythrocytes. Suitable accessories for all applications If the standard accessories are not suited for special applications, customized accessories to meet specific requirements can be manufactured within a very short time. Also, customized accessories have been developed for blood banks and stem cell banks, where they are used to process placental blood and stem cells in blood bag systems of lower volume. The perfect team: ROTO SILENTA 630 RS and the PRESSOMAT Optimally matching accessories facilitate shorter processing times, better preparation quality and higher yields. The ROTO SILENTA 630 RS with blood bag insert 4598-P and the PRESSOMAT plasma separator form a perfect combination. Centrifugation and separation take place in the same insert. Since it is not necessary to manipulate the blood bag system during transportation from the centrifuge to the separator, any disturbance of the erythrocytes is avoided. Centrifugation and separation in the same insert. 2

3 PRODUCTS AND ACCESsORIES FOR BLOOD BANKS ROTO SILENTA 630 RS More efficient processes and better results thanks to: l Easy loading of the large carriers even with blood bag systems with inline filters l Centrifugation in a swing-out rotor with a maximum RCF of 6,520 without a windshield Energy is saved since the cooling acts directly on the centrifuged material. Cleaning of the rotor and centrifuge chamber is not impeded by a windshield. Smooth running since possible damages of the windshield have no adverse effect on the aerodynamics of the rotor. l Powerful, maintenance-free, quiet in operation and reliable l Efficient cooling within a temperature range of -20 C to +40 C also creates ideal conditions for the preparation of cryoprecipitates at 4 C l Ergonomic arrangement of the control elements Special braking system prevents re-suspension of the sediment when decelerated rapidly Well-conceived design and good insulation generate low noise levels A complete program Accessories are also available for blood bag centrifugation in smaller models such as the ROTIXA 50 RS, and the ROTANTA 460 R, 460 RC and 460 RF. The HettInfo documentation system logs the processing data and the quality of the blood products derived. The range of blood bank equipment is completed by the ROTOLAVIT cell washing system which is used to test the compatibility of donor and recipient blood. Scanning with an external barcode unit or directly at the centrifuge. 3

4 SEPARATION OF BLOOD COMPONENTS Blood is centrifuged to separate it into its basic components - erythrocytes (red blood cells), leucocytes (white blood cells), thrombocytes (platelets) and plasma. These constituents of the blood sediment at different rates according to their density. The erythrocytes collect at the bottom above them the leucocytes, followed by the thrombocytes. The leucocytes and thrombocytes together form a thin white layer known as the buffy coat. The plasma is above the buffy coat. Buffy Coat method 1a Since the standards that govern the demands on the preparation of blood products and their quality vary between countries, different methods are adopted. The most common methods are outlined below: 1b 1. Buffy Coat method Preparation of platelet poor plasma and concentrated red cells from unfiltered whole blood with subsequent production of platelet concentrate from the buffy coat Centrifugation at a high RCF separates the blood into platelet poor plasma (PPP), buffy coat (BC) and concentrated red cells (CRC) with a small proportion of leucocytes. A plasma separator presses the platelet poor plasma (PPP) into one satellite bag, the concentrated red cells (CRC) into another. The buffy coat (BC) remains in the primary bag (1a). The remainder of the leucocytes in the CRC can be removed by filtration. In a subsequent centrifugation step at a low RCF the BC is separated into platelet concentrate (PC), a residual BC and a small volume of sediment containing leucocytes and erythrocytes. The PC is pressed into a satellite bag. The remainder of the constituents are left in the primary bag (1b). In countries where it is not prohibited, the platelet concentrate is prepared from pooled buffy coat. Pooled BC comprises 4 to 6 individual buffy coats that are allowed to flow into one bag. The pool is separated by centrifugation at a very low RCF into PC, a residual buffy coat and a sediment comprising erythrocytes and leucocytes. Upon subsequent expression of the PC it flows through a filter, removing most of the leucocytes and erythrocytes still present in the PC. This yields platelet concentrate that is low in leucocytes. alternative: 1c 1d PCs prepared from pooled buffy coat have higher numbers of thrombocytes (i.e. a higher therapeutic dose) and fewer variations in quality. 4

5 2. Pre-filtered whole blood Preparation of platelet poor plasma and concentrated red cells from filtered whole blood Pre-filtered whole blood (e.g. application of the PRESSOMAT) 2a 2b With this method the buffy coat is filtered from the whole blood prior to centrifugation (2a). The subsequent centrifugation step at a high RCF separates the filtered blood into platelet poor plasma (PPP) and concentrated red cells (CRC). The constituents separated by a plasma separator are then collected in satellite bags (2b). 3. PRP method Preparation of platelet rich plasma and concentrated red cells from unfiltered whole blood with subsequent preparation of platelet concentrate and platelet poor plasma In a first centrifugation step at a relatively low RCF unfiltered whole blood is separated into platelet rich plasma (PRP) and concentrated red cells (CRC). The PRP is expressed into a satellite bag (3a). The leucocytes still contained in the CRC are removed through filtration. PRP method 3a In the second centrifugation step at a higher RCF the PRP is separated into platelet poor plasma (PPP) and platelet concentrate (PC) (3b). 3b Key to symbols: centrifugation pooling separation filtration 5

6 CONTROL PANELS Simple to program With the S and C control panels, even the most complex centrifuge runs can be programmed quickly and easily. The individual parameters are selected by way of symbol keys, the desired values are set with the rotary knob and stored by pressing the STO key (S control panel) or the START key (C control panel). The operating and display elements are clearly laid out and easy to read. The actual status of all parameters is displayed during operation. The display/entry of RPM can be converted to display/entry of RCF by pressing a button. S CONTROL PANEL (ROTO SILENTA 630 RS and ROTIXA 50 RS) KEYPAD START Starts centrifugation run, short-time centrifugation. Pre-cooling can be assigned to one program location. A PIN code is entered in centrifuges with a C control panel to prevent unauthorized entry or modification of the stored programmes. Models with an S control panel feature a key-operated switch for locking. Centrifuges with C control panel further permit the centrifugation time to be switched from at start (commencing upon start) to at speed (start when the set speed has been reached). STOP PROG STO RCL RCF Stops centrifugation manually. Selects the program. 89 programmable memories are available. Stores entries, changes and programmes. Calls up the selected program. The integral over the RCF indicates the accumulated RCF acting on the centrifuged material up to that particular time. PARAMETER INPUT Entry of the temperature from 20 C to +40 C in increments of 1 C with refrigerated centrifuges. Entry of the centrifuging radius in mm. Entry of the run-up time in ramps 1 9 or in min : sec. Entry of the run-down time in ramps R 1 9 and B 1 9 or in min : sec. Also unbraked run-down (setting 0), or a brake force cut-off speed can be selected. RCF Entry of the RCF in increments of 1. n Entry of the speed in increments of 10. t Entry of the centrifugation time (max. 999 min : 59 sec) or continuous operation. OPTIONS WITH BOTH CONTROL PANELS Data documentation (HettInfo) see pages 18/19 Program interlocking to combine several centrifugation runs 6

7 SEPARATION PERFORMANCE Best separation results C CONTROL PANEL (ROTANTA 460 R, 460 RC and 460 RF) KEYPAD START Starts centrifugation run, short-time centrifugation, saves entries and changes, stores programs. Starts pre-cooling program PREC. The braking characteristics of the rotor have a decisive influence on the quality of separation achieved, especially at low centrifugation speeds, such as those commonly run in the preparation of thrombocyte concentrate (TC) or platelet rich plasma. The regular R-ramps brake the rotor uniformly over the entire t down time. Loosely packed sediment may be resuspended during this critical run-down phase. In contrast to this, the B-ramps brake the rotor rapidly, at first, then slowly so that it gently comes to standstill. STOP Stops centrifugation manually / OPEN Opens the lid. PROG RCF Entry / recall of the program number. 98 programmable memories are available. Pressing the RCF key several times results in display of the integral over the RCF. Speed (n) in 1000 min t e t z Time Deceleration ramps t down PARAMETER INPUT B-ramps enable the buckets to return to a vertical position gently and without vibration, before coming to a stop. T/ C Entry of the temperature from 20 C to +40 C ( 4 F to +104 F) in increments of 1 with refrigerated centrifuges. Entry of the run-up time in ramps 1 9 or in min : sec. Entry of the run-down time in ramps R 1 9 and B 1 9 or in min: sec. Also unbraked run-down (setting 0), or a brake force cut-off speed can be selected. RCF Entry of the RCF in increments of 1. Entry of the centrifugation radius in mm. RPM Entry of the speed in increments of 10. TIME Entry of the centrifugation time (max. 99 h : 59 min : 59 sec) or continuous operation. As with the R-ramps, a speed can also be entered for the B-ramps at which the brake is disengaged. The rotor then comes to a stop without braking. Speed (n) in 1000 min t e t z Deceleration ramps t down Braked run-down Run-down without braking Time Braking characteristics of the rotor with B-ramps, based on disengagement of braking at a speed of 500 min -1. 7

8 MODEL VARIANTS Adaptability ROTO SILENTA 630 RS and ROTIXA 50 RS centrifuges adapt to the most diverse local conditions and requirements. Depending on fittings, they can be connected to an external cooling unit an external cooling medium circuit an external coolant circuit, cooling unit integrated We are happy to meet the special requirements of our customers. If you have any questions, special wishes or ideas, please phone us or send an to If necessary, our specialists can provide advice at your premises. If we are not able to visit you, we will send our specially trained contract partners. green = cooling medium (R 404A), blue/red = coolant RotO SILENTA 630 RS Variant Power supply* ) Frequency Cat. No. Standard, with internal transformer 208 V 3~ +N 60 Hz Of course, a stand-alone option is also available. It is the air-cooled standard model with an integrated cooling unit. The casing of all variants can be sealed for use under clean room conditions. In addition, the pedestal can be covered and sealed off from the floor. External connections can also be routed through the base of the unit. Standard, with internal transformer 220 V + 6/-10 % 3~ (+N) 60 Hz A Brine cooling 400 V 3~ +N Hz GMP, internal cooling unit with water-cooled condenser GMP, external cooling unit 400 V 3~ +N Hz V 3~ +N Hz Rotixa 50 RS GMP, external cooling unit GMP, internal cooling unit with water-cooled condenser V Hz V Hz

9 ROTO SILENTA 630 RS Safe and economic preparation of blood products The ROTO SILENTA 630 RS accommodates up to 12 x 750 ml blood bag systems per run. Its optimal running performance guarantees best separation results. The Hettich data report system HettInfo as well as customised solutions enable GMP performance and meet the high standards of user safety and product quality in blood banks and transfusion centres. Technology Frequency-controlled drive, virtually maintenance-free Powered lid locking Ergonomic rail-grip for easy lid closing Large viewing port in the lid for optical speed control with a stroboscope Safety Imbalance switch-off Rotor recognition Key-operated switch for locking and protecting programs Lid locking and holding Lid dropping protection Motor and chamber overheating protection Torsion-free steel chassis Smooth, easy to clean surfaces ROTO SILENTA 630 RS with barcode unit (option), dimensions (H x W x D): 973 x 813 x 1,015 mm (without barcode unit), 973 x 888 x 1,015 mm (with barcode unit). On request, the scanner can also be mounted on the left panel. Technical data ROTO SILENTA 630 RS >) Floorstanding centrifuge, without rotor, cooled Power supply* ) 400 V 3 ~ + N Frequency Hz Consumption 9,700 VA Emission, Immunity EN / IEC , class B Max. capacity 6 x 2,000 ml / 12 x 750 ml blood bag systems Max. RPM (speed) 4,500 min -1 Max. RCF 6,520 Running time 1 sec 999 min : 59 sec, continuous run Dimensions (H x W x D) Weight 973 x 813 x 1,015 mm approx. 355 kg Refrigeration Temperature control, infinitely variable from - 20 to + 40 C Cat. No >) Model variants on request. * ) Other voltages on request. 9

10 Rotors and accessories Swing-out rotor, 6-place ) 90 n = 4,500 min 1 max. RCF 6,520 Cat. No. (without carriers) 4176 illustrated with carriers 4591-A and inserts 4592-H capacity in ml holding system for blood bags Baxter/ Fenwal Fresenius Terumo 2) blood bags quadruplicate quadruplicate quadruplicate quadruplicate quadruplicate single Cat. No ) ) ) - - capacity in ml 450 blood bags, quadruplicate Cat. No. - carrier Cat. No Cat. No ) -O,-M,-U 4592-H boring Ø x L in mm - blood bag systems per rotor max. RCF max. RCF 4) radius in mm run-up in sec run-down in sec, braked temperature in C 1) ,498 5,683 1,000 1, carrier Cat. No Cat. No H boring Ø x L in mm - blood bag systems per rotor max. RCF radius in mm run-up in sec run-down in sec, braked temperature in C 1) 12 6, , capacity in ml blood bags triplicate triplicate quadruplicate single Cat. No carrier Cat. No A Cat. No P 4592-H boring Ø x L in mm - blood bag systems per rotor max. RCF radius in mm run-up in sec run-down in sec, braked temperature in C 1) ,498 5, carrier 4524 with insert 4525 carrier 4524 with insert 4529-O with hooks in upper position 1) Lowest attainable temperature in precooled refrigerated centrifuges at max. speed. Lower temperatures can be reached by reducing the speed. 2) As well as Macopharma and Kawasumi. 3) Please order by pairs. 10

11 Swing-out rotor, 4-place ) 90 n = 4,500 min 1 max. RCF 5,705 Cat. No. (without carriers) 4174 illustrated with carriers 4591-A and inserts 4592-H capacity in ml 100 thrombocyte plate Cat. No ) capacity in ml ,000 blood bags quadruplicate single single Cat. No. - - carrier Cat. No A for 4 plates Cat. No boring Ø x L in mm - qty. per rotor max. RCF max. RCF 5) radius in mm run-up in sec run-down in sec, braked temperature in C 1) ,316 5,501 1,000 1, carrier Cat. No A Cat. No boring Ø x L in mm - - blood bag systems per rotor max. RCF radius in mm run-up in sec run-down in sec, braked temperature in C 1) 6 4 6,452 5, ,520 5, carrier 4591-A with insert 4592-H carrier 4595-A, insert 4596 and 4 thrombocyte plates 4597 carrier 4523-A with insert 4516 carrier 4546 with insert 4559-H 4) When using inserts 4529-O, 4529-M, 4529-U at lower speeds (e.g. for processing thrombocytes), the blood bags may be hung up to avoid accumulation of erythrocytes. Hooks at three different heights (4529-O upper position, 4529-M middle position, 4529-U low position) allow to meet specific customer requirements. Suspended blood bags, however, may not be exposed to a RCF exceeding 1,000. 5) The max. permissible RCF for centrifuging thromboplates 4597 is 1,

12 ROTIXA 50 RS Large floorstanding centrifuge for single-phase alternating current Generating a maximum RCF of 5,252, which it also attains without a windshield, the ROTIXA 50 RS is suited for separating a wide range of samples such as food and beverage, cell suspensions, sediments of chemical reactions, sludge and, of course, blood and blood components. Per run, the ROTIXA 50 RS can process up to 4 x 750 ml (quadruplicate) or 4 x 1,000 ml (single) blood bag systems. Technology Frequency-controlled drive, virtually maintenance-free Smooth and quiet running Exceptional speed stability Viewing port in the lid for optical speed control with a stroboscope Safety Imbalance switch-off Rotor recognition Key-operated switch for locking and protecting programs Lid locking and holding Lid dropping protection Motor and chamber overheating protection Smooth, easy to clean surfaces ROTIXA 50 RS Cat. No Technical data ROTIXA 50 RS >) Floorstanding centrifuge, without rotor, cooled Power supply* ) V 1~ Frequency Hz Consumption 3,680 VA Emission, Immunity EN / IEC , class B Max. capacity 4 x 1,000 ml / 4 x 750 ml blood bag systems Max. RPM (speed) 4,500 min -1 Max. RCF 5,252 Running time 1 sec 999 min : 59 sec, continuous run Dimensions (H x W x D) Weight 1,030 x 650 x 720 mm approx. 172 kg Refrigeration Temperature control, infinitely variable from - 20 to + 40 C Cat. No >) Model variants on request. * ) Other voltages on request. 12

13 Rotors and accessories Swing-out rotor, 4-place ) 90 n = 4,500 min 1 max. RCF 5,252 Cat. No. (without carriers) 4294 illustrated with carriers 4293 and inserts 4244 illustrated with carriers 4298 and inserts 4237 capacity in ml blood bags, triplicate Cat. No. - - capacity in ml ,000 blood bags quadruplicate single single Cat. No. - - carrier Cat. No Cat. No boring Ø x L in mm - blood bag systems per rotor 4 max. RCF 5,252 radius in mm 232 run-up in sec 108 run-down in sec, braked 103 temperature in C 1) + 6 carrier Cat. No Cat. No boring Ø x L in mm - - blood bag systems per rotor 4 4 max. RCF 5,003 5,071 radius in mm run-up in sec 108 run-down in sec, braked 103 temperature in C 1) + 6 carrier 4293 with insert 4244 carrier 4298 with insert ) Lowest attainable temperature in precooled refrigerated centrifuges at max. speed. Lower temperatures can be reached by reducing the speed. 13

14 ROTANTA 460 R, 460 RC and 460 RF Blood bags in benchtop centrifuges are only a matter of performance and accessories Enhanced performance and an extended range of accessories even allow to centrifuge blood bags in benchtop models. In addition to a wide range of sample tubes, the refrigerated ROTANTA 460 centrifuges accept 4 x 450 ml triple or quadruple blood bag systems. To ensure their quality, all data of the preparation process of blood products in centrifuges with C control panel may also be documented with HettInfo. Technology Frequency-controlled drive, virtually maintenance-free Powered lid locking Easily exchangeable rotors Viewing port in the lid for optical speed control with a stroboscope ROTANTA 460 R benchtop centrifuge, cooled Cat. No Safety Imbalance switch-off Rotor recognition PIN code for locking and protecting programs Lid locking and holding Lid dropping protection Motor and chamber overheating protection Technical data ROTANTA 460R >) Benchtop centrifuge, without rotor, cooled Power supply* ) V 1 p V 1 ~ 100 V 1 ~ Frequency 50 Hz 60 Hz 50 Hz Consumption 1,800 VA 2,000 VA Emission EN / IEC , FCC class B Immunity class B - Max. capacity 4 x 750 ml / 4 x 450 ml blood bag systems Max. RPM (speed) 15,000 min -1 Max. RCF 24,400 Running time 1 sec - 99 h : 59 min : 59 sec, continuous run, short cycle mode Dimensions (H x W x D) 456 x 770 x 706 mm Weight approx. 133 kg approx. 143 kg Refrigeration Temperature control, infinitely variable from - 20 to + 40 C Cat. No >) Model variants on request. * ) Other voltages on request. 14

15 ROTANTA 460 RC underbench centrifuge, cooled Cat. No ROTANTA 460 RF floorstanding centrifuge, cooled Cat. No ROTANTA 460 RC ROTANTA 460 RF Power supply* ) Frequency Consumption Emission Immunity Underbench centrifuge, without rotor, cooled Floorstanding centrifuge, without rotor, cooled V 1 p 50 Hz 1,800 VA EN / IEC , class B Max. capacity 4 x 750 ml / 4 x 450 ml blood bag systems Max. RPM (speed) 15,000 min -1 Max. RCF 24,400 Running time 1 sec - 99 h : 59 min : 59 sec, continuous run, short cycle mode Dimensions (H x W x D) 683 x 554 x 697 mm 961 x 554 x 697 mm Weight approx. 140 kg approx. 164 kg Refrigeration Temperature control, infinitely variable from - 20 to + 40 C Cat. No

16 Rotors and accessories Swing-out rotor, 4-place ) 90 n = 4,600 min 1 max. RCF 5,063 Cat. No. (without carriers) 5624 illustrated with carriers 5691-A and inserts 5692 capacity in ml 450 Ø x L in mm Cat. No. lid with bio-containment 2) Cat. No triplicate system without filter blood bags capacity in ml 450 blood bags triplicate system quadruplicate system Cat. No holder for systems without filter holder for systems with or without filter carrier Cat. No A Cat. No. - boring Ø x L in mm - blood bag systems per rotor 4 max. RCF 2) 5,063 radius in mm 214 run-up in sec 90 run-down in sec, braked 95 temperature in C 1) +4 carrier Cat. No A Cat. No boring Ø x L in mm - blood bag systems per rotor 4 max. RCF 2) 4,637 radius in mm 196 run-up in sec 90 run-down in sec, braked 95 temperature in C 1) +11 carrier 5691-A, insert 5692 and holders 5693 and ) Lowest attainable temperature in precooled refrigerated centrifuges at max. speed. Lower temperatures can be reached by reducing the speed. 2) Tested by the TÜV in conformity with DIN EN 61010, section

17 Certificates and registrations Quality and safety Hettich centrifuges comply with all relevant EU standards in effect. All stages from design to end-product are continuously subjected to the strictest controls. Evidence is provided by national and international test marks such as IEC or the CE conformity. The ISO 9001, ISO and ISO certificates accredited to the company bear witness to the extreme care and responsibility Hettich puts into the manufacturing of centrifuges and their accessories. This is why Hettich centrifuges are known for safety and reliability all over the world. Marks of conformity for the use of Hettich centrifuges in the US and Canada, on request. according to directive 98/79/EC IvD stands for In-vitro Diagnostics. Hettich centrifuges conform to IvD standards, i.e. they comply with the European IvD guideline s requirements (98/79/EC) and guarantee a standardised level of quality and safety. Please see 15 Data Storage of our General Terms and Conditions regarding the traceability of Hettich products. Non-polluting waste disposal Since , Hettich has been registered in Germany under WEEE Reg. No. DE with the Elektro-Altgeraete Register 1) - Foundation for the implementation of the 2002/96/EC directive (ElektroG 2) ), regarding the disposal of electrical and electronic equipment in the EU. With the symbol of the crossed-out bin, it is made clear that centrifuges may not be disposed of with household waste. The disposal regulations in the individual EU countries can vary. Please ask your supplier, if necessary. In this context, we refer to 14 Acceptance of returns / obligation to dispose of the goods of the General Terms and Conditions. 1) Register of old electronic equipment 2) Electrical and Electronic Equipment Act 17

18 HettInfo HettInfo guarantees reliability, transparency and flexibility of data documentation. Data documentation and traceability have to satisfy increasingly stringent requirements. As a consequence, more and more time has to be spent on documentation. With HettInfo transparency can be increased and at the same time processes can be streamlined and rationalized. Packing room with external barcode unit The HettInfo data documentation system consists of combinable modules and can be easily adapted to the required number of centrifuges. Up to 29 centrifuges and 3 external barcode units can be integrated into the network, which is reliable and absolutely immune to disturbances. HettInfo enables logging of all centrifugation data. The user can log the date, end of the centrifugation run, program number and the temperature, and can select and de-select additional optional parameters. If barcode kits are used, the barcodes of blood bags and users can also be logged. In addition, the result of each run is automatically stored with all logged data. This simplifies any search for incorrect centrifuge runs. Modern data back-up mechanisms increase data integrity. To avoid duplication and to ensure that higher-level databases are kept up to date, all data acquired using HettInfo can be integrated into these databases. For this, the data is stored in CSV format at the desired storage location. Time-consuming and costly programming of the interface is not required. Barcode Online Kit ROTO SILENTA 630 RS Program functions that can be connected: HettInfo Light Cat. No L HettInfo Cat. No F 29 centrifuges 29 barcode kits 3 external barcode kits Logging and storage of process data: Centrifugation programs and the operator code can also be scanned-in by barcode. Data log Daily run time data Overall run time data Barcode result data User barcodes and users Centrifuge fault tables Minimum PC requirements (available from specialist computer resellers) Processor Pentium Clock frequency 1 GHz RAM 512 MB Hard disk 10 GB Interface free RS 232 VGA graphics card 1 MB Resolution 1024 x 768 (16 bit) Operating system Microsoft Windows XP # (SP 2) Additional components: network adapter card (available from specialist computer resellers) Database functions: Delete table data Print centrifuge report table Print centrifuge fault table Print barcode report table Print barcode fault list Print duplicate barcodes Search barcodes Delete packing room data Password protection Packing room User administration 18

19 Participants The data collected through HettInfo by the participants is stored on a PC with a RS 232 interface. Participants are centrifuges with an online kit or a barcode online kit, external barcode units and additional distributors. In principle any centrifuge with an S or C control panel can be connected to HettInfo through an online kit. Barcodes can also be captured and documented through the use of a barcode online kit or an external barcode kit. To serve the function of a barcode online kit, an external barcode kit must be used in combination with an online kit. In addition to barcodes on blood bags, user data can also be captured via barcodes. This ensures full traceability and saves time and labour. Key to symbols: 888 Capture of centrifuge data Scanning of barcodes Article Cat. No. Scope of supply Basic Kit HettInfo Basic Kit HettInfo Light 0910-F c) Software with all functions (full version), fibre-optic cable b) for connection to one participant or distributor, RS 232 cable, opto data box 0910-L c) Software with limited functionality, fibre-optic cable b) for connection to one participant or distributor, RS 232 cable, opto data box Online Kit Opto interface for a centrifuge with S control panel, barcode capture only if used with ; included in and Barcode online Kit ROTIXA 50 RS d) Front panel for ROTIXA 50 RS with barcode unit and barcode scanner; includes Online Kit ( ) Barcode online Kit ROTO SILENTA 630 RS d) Front panel for ROTO SILENTA 630 RS with barcode unit and barcode scanner; includes Online Kit ( ) Data distributors With HettInfo, up to 29 centrifuges can be controlled by a single PC. The data distributors for this are pre-installed and have robust optical cables for connection. Everything is provided for start-up. 888 Barcode Kit, external for a packing room or for use on a centrifuge with C or S control panel and Online Kit c) Barcode station with barcode scanner Distributor, small 0919-S02 c) to 0919-S08 c) With fibre-optic cables a), for connection of 2 to max. 8 participants Distributor, large 0919-L02 c) to 0919-L15 c) With fibre-optic cables a), for connection of 2 to max. 15 participants # Microsoft, Windows and Windows XP are either registered trademarks or brand names of the Microsoft Corporation in the USA and/or in other countries. a) Fibre-optic cable in standard length (10 metres). Other lengths on request. b) Fibre-optic cable in standard length (20 metres). Other lengths on request. c) V version, Hz d) 230 V version. Other voltages on request. 19

20 PRESSOMAT The plasma separator with innovative functionality The PRESSOMAT was developed for the production of leucocyte-depleted plasma and leucocyte-depleted erythrocyte concentrate. Its functional principle is quite unique: centrifugation as well as separation take place in the centrifuge insert (= two-chamber insert 4598-P). During transportation from the centrifuge to the PRESSOMAT, the blood bag system is not manipulated, and dispersion of the erythrocytes is thus avoided. Moreover, pressing two blood bags simultaneously saves valuable time. PRESSOMAT Cat. No. (without accessories) 1070 Technical data Power supply Frequency Emission, Immunity Pressomat V / 2.5 A Hz EN / IEC , class B Dimensions (H x W x D) 850 x 280 x 380 (450 *) Weight 16.5 kg Pump capacity 2 x 600 mbar Max. pressing speed (flow rate) 6 ml / sec Pressomat Two-chamber insert with Pneumatic Kit Cat. No P Accessories HettControl (Basic Kit incl. software) Barcode Kit Taring rods Cat. No On request * ) with extended sliding carriage 20

21 The blood bag system An increasing number of blood donation facilities are taking advantage of the benefits of whole blood inline filtration, as long as the buffy coat is not required for the preparation of platelet concentrates. The PRESSOMAT was specially developed for pre-filtered whole blood in a ml T&T blood bag system. Blood bag systems from all suppliers which fulfil the following configuration may be used: Benefits Simultaneous pressing of two blood bags Separation in the centrifuge insert for optimal product quality. Removing the bags prior to separation is no longer required Automatic feeding of the nutrient solution into the concentrated red cells (CRC) Optimised process safety via optical and acoustic signals Maximum plasma recovery thanks to recognition of the erythrocytes at the tube Compressor not required Over 50% time savings Sample bag Needle Primary bag Inline filter Bag with nutrient solution Plasma bag Transfer bag for filtered whole blood Equipment Integrated, process-independent sealing module 2 calibration-compatible scales: Record plasma weight Record the volume of nutrient solution fed to the concentrated red cells Weigh the concentrated red cells 2 optical sensors: Secure recognition of the erythrocytes at the tube Are automatically calibrated with each new pressing process Interfaces for barcode reader and PC Taring rods to balance eventual weight discrepancies during centrifugation Data documentation system HettControl (optional) Side chamber for the satellite bags The satellite bags can be easily removed for separation, without dispersing the sedimented erythrocytes in the main chamber. Main chamber for the blood bag Following centrifugation, the blood bag remains in the centrifuge insert. The two-chamber insert is then placed on the pneumatic coupler of the PRESSOMAT s sliding carriage. After that, the press bag is filled with air and the plasma is pressed into the satellite bag. Pneumatic Kit Press bag and pneumatic coupler with an unlocking device for easy mounting and demounting of the two-chamber insert from the PRESSOMAT s sliding carriage. Two-chamber insert incl. Pneumatic Kit Cat. No P 21

22 ROTOLAVIT Automatic cell washing system for serological testing In blood banks and transfusion centres, it is routine practice to test the compatibility between donor and recipient prior to every blood transfusion. This test is quite labourintensive. Especially the washing of the erythrocytes takes a lot of time. The ROTOLAVIT cell washing system carries out the washing process automatically, hence reducing the workload and saving valuable time. The appropriate quantity of saline solution is filled equally into 12 or 24 tubes, depending on the rotor, and mixed with a previously pipetted drop of blood. It is then centrifuged and the supernatant is decanted. The washing cycle is repeated several times and the anti-human globulin (Coombs) serum is then added manually, in order to assess possible agglutination following the final centrifugation. Areas of application Cross-matching Antibody search and differentiation ROTOLAVIT Cat. No Technology Microprocessor control Frequency drive 5 programmable memories Max. RCF 1,438 (3,500 min -1 ) User-friendliness Effortless cleaning Easy rotor changing A visual and acoustic signal warns when the saline solution container is empty One-handed lid closing Safety Lid locking and holding Lid dropping protection Emergency lid lock release Metal housing Imbalance switch-off Motor cut-off at standstill Technical data ROTOLAVIT Cell Washing System, without rotor Power supply* ) V 1 ~ V 1 ~ Frequency Hz Consumption 180 VA Emission, Immunity EN / IEC , class B FCC class B Max. capacity 24 standard tubes (10 x 75 mm or 12 x 75 mm) Max. RPM (speed) 3,500 min -1 Max. RCF 1,438 Radius (both rotors) 105 mm Running time of the individual washing cycles 1 sec 9 min : 59 sec Dimensions (H x W x D) Weight 278 x 333 x 420 mm approx. 24 kg Cat. No * ) Other voltages on request. 22

23 The washing process is repeated automatically, allowing up to 9 sequenced washing cycles to be programmed freely. Rotor, 12-place Rotor, 24-place A washing cycle includes the following steps: 1. Filling the saline solution 2. Centrifuging at (usually) 3,500 min Decanting the supernatant 4. Resuspending the sediment (between cycles only) 5. Decanting the supernatant ) 45 ) 45 Cat. No A Cat. No A Either for standard tubes 10 x 75 mm or 12 x 75 mm. Cat. No. for 12 x 75 mm tubes: OPERATION AND CONTROL The use of 10 x 75 mm tubes requires adapters No digital DISPLAY and control panel display keypad PROG CYC ml RPM t/min:s Program number. Five programmable memories are available. Washing cycles. A maximum of nine washing cycles can be entered. Volume of saline solution per tube (max. 5 ml). Speed indication. Entry in increments of 10. Centrifugation time (max. 9 min : 59 sec). START WASH SPIN Guides the user through the menu options. Increases the relevant value. Decreases the relevant value. Starts washing, the production of a suspension or the cleaning program. Starts additional centrifugations, e.g. Coombs centrifugation. An LED lights up: in the event of imbalance, STOP Stops centrifugation or washing manually. as long as the rotor is rotating, when the lid can be opened on completion of the program. SALINE Activates the fill volume calibrator. Charges the system with washing liquid during the cleaning program. CHECK Checks the volume of saline solution per washing cycle. 23

24 Products and accessories for blood banks Hettich centrifuges comply with all relevant EU standards in effect and conform to the European level of quality and safety for medical devices. Evidence is provided by national and international test marks such as IEC or the CE conformity. The ISO 9001, ISO and ISO certificates accredited to the company bear witness to the extreme care and responsibility Hettich puts into the manufacturing of centrifuges and their accessories. P-Blutbank-GB.0710 by Andreas Hettich GmbH & Co.KG, Tuttlingen Printed in Germany Design, form and colour modifications reserved. Andreas Hettich GmbH & Co. KG Föhrenstr. 12 D Tuttlingen Germany Phone +49 (0)7461/705-0 Fax +49 (0)7461/ National Sales: -200 International Sales: -201 National Service: -202 International Service: -203