BioStore II. Flexible, Modular, -80 º C Automated Sample Storage. Improving Sample Quality with Controlled Cold Chain Management

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1 BioStore II Flexible, Modular, -80 º C Automated Sample Storage Improving Sample Quality with Controlled Cold Chain Management

2 BioStore II: Flexible, Modular, Controlled -80 º C Storage ASK BROOKS Over 250 stores and more than a billion samples managed worldwide. Our focus is sample management we are the experts With almost 20 years of experience and over 250 automated stores installed worldwide, Brooks understands biological and compound sample management. Brooks delivered the world s first automated -20 C store in 1997 and, in 2008, expanded its product offering to include -80 C automated storage. Brooks has become the partner of choice for researchers around the world, including 9 of the top 10 pharmaceutical companies and many of the world s leading biobanks. Based on standard modules, Brooks delivers reliable, flexible automated storage solutions. BioStore II is one of the results of a multi-million dollar investment to develop industry-leading automated sample management tools. Ask Brooks: Brooks Strategic Advisory Services provide advice and expertise on sample management, whether you are just starting to think about a small sample collection or are managing a large-scale collection of millions of samples held in many locations. The Brooks team has experience of a wide range of applications; from managing of compound samples for drug research to processing samples of DNA, serum, and tissue for biorepositories to overcoming the challenges of viable cell storage. We can provide guidance on sample collection, preparation, storage, output and distribution as well as storage containers and sample quality. We know that you achieve significant value from your samples by having a known, controlled history and origin coupled with efficient, reliable handling processes BioStore II delivers in all areas. Brooks BioStore II the result of $millions of investment

3 MODULAR AND FLEXIBLE BioStore II: Expand or Upgrade as Needs Change -80 C CONDENSERS -80 C MODULE BAYS INPUT/OUTPUT AND SAMPLE IMAGING MODULES RANGING DOWN TO -20 C Biostore II: SingleBank BioStore II is the next generation in automated -80 C sample management You have plans to invest in a new automated sample storage system to hold samples at -80 C. You plan on the system having many years of life. However, the future is full of uncertainty. BioStore II offers the flexibility that is required for an unpredictable world: Standard configurations include: SingleBank, TwinBank and QuadBank - expandability options to meet the needs of an unpredictable future. Collection variability: Handle your changing repository collections: BioStore II is designed to handle a diverse set of container types and evolve with your collection. Increase capacity or change picking and input/output modules to meet future requirements or container types. Standard module options: Standard configurations include -20 C and -80 C picking modules as well as input/output. Sample flexibility: Sample picking modules are designed for a wide range of containers, including non-sbs formatted vials, tubes, and many cryoboxes. Easy to service: The picking and input/output modules can be serviced from outside without disturbing the stored samples or bringing moisture into the storage compartment. Maximize storage density: Dynamically allocated storage space; even if your sample containers change, storage capacity will be optimized.

4 PERFORMANCE Preserving Sample Integrity through Controlled Cold Chain Management Sample integrity is our top priority Best-in-class temperature homogeneity: By placing the evaporators above the samples, your samples will experience the same temperature no matter where they are located in the BioStore II. Minimize thermal disruption when accessing samples: A passive tile wall insulates the storage compartment and allows for rapid sample access. When samples are requested, less than 1% of the tile wall is opened. This ensures innocent samples are not exposed to unnecessary temperature cycling. Resilience: The BioStore II has fully redundant refrigeration circuits, dedicated UPS, and the option for liquid nitrogen backup in case of power failure. Maintain -80 C sample temperature when picking: BioStore II offers optional -80 C picking, both picked and innocent samples can be maintained at -80 C. Cold from the evaporators falls directly on to samples Industry-leading temperature homogeneity Storage bays Evaporator Stage 1 condenser -80 C evaporator above samples: Even temperature distribution Minimal temperature gradient Air temperature uniformity: Trials show less than 3 C from temperature setpoint BioStore II: TwinBank to meet today s collections BioStore II: QuadBank, as your collection grows I/O module and picker

5 ULTIMATE FLEXIBILITY Dynamic Storage Capabilities Whether your samples are in plates, tubes, vials, or many cryoboxes, BioStore II is designed to handle them all. On input, the imaging unit verifies the sample ID and container height and type; this makes input a simple intuitive effort. SBS (ANSI-SLAS) Cryoboxes Tubes Vials Dynamic Storage Configure to a wide range of capacities Model Length Width Height Tube type Capacity BioStore II SingleBank BioStore II TwinBank BioStore II QuadBank REMP 300 ul with seal 950, m 3.3m 2.8m FluidX 0.7 ml with jacket 869, REMP 300 ul with seal 1,900, m 3.6m 2.8m FluidX 0.7 ml with jacket 1,730, REMP 300 ul with seal 3,800, m 4.5m 2.8m FluidX 0.7 ml with jacket 3,470,000

6 BioStore II is Easy and Convenient to Use No special engineering expertise is required to operate the system Using BioStore II is completely intuitive with Brooks Strata store control software. The simplified user interface can be easily configured for day-to-day operation with more detail available via drill down and advanced screens for super users. Strata can be operated on a PC or remotely from any web-enabled device. Strata simplifies integration with Corporate IT systems and LIMS supporting Web Services and other technologies. Strata ensures reliable performance via intelligent diagnostics and error recovery. The result is savings in time and money: your staff can focus on the science rather than taking care of the automation. BioStore II as a shared resource Centralized storage with BioStore II puts sample management in the hands of the experts! Strata s ability to group individual sample collections, or re-array stored samples, opens the door to new business models in sample management. Defined user access privileges adds security and control to collection management, whilst allowing new sample collaboration opportunities. Typical detailed Dashboard User Selectable language Strata on PC or mobile device Drill down for more detail United States United Kingdom Japan 15 Elizabeth Drive Northbank, Irlam Nisso Bldg. No 16, 9F Chelmsford, MA Manchester M44 5AY Shin-Yokohama, Kohoku-Ku T: T: +44 (0) Yokohama, Kanagawa T: Visit us online at: or blss.sales@brooks.com en-US 04/15 Copyright 2015 Brooks Automation, Inc. Brooks Automation, Brooks Life Science Systems, and the Brooks logos are trademarks of Brooks Automation, Inc. All other trademarks are the property of their respective owners. This product contains fluorinated greenhouse gases with a global warming potential of 150 or greater.