Flavors & Fragrances. Innovative Solutions Improve Quality, Productivity & Safety

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1 Flavors & Fragrances Innovative Solutions Improve Quality, Productivity & Safety

2 Overview Improve Processes & Quality Control Across Your Value Chain The flavor and fragrance manufacturing industry faces several challenges. Increasing safety requirements and regulatory compliance needs, improving productivity while increasing product quality, responding fast to market demands are just a few. Thus, when it comes to precise scales, balances and analytical instruments you need a reliable and powerful partner supporting you with complete weighing solutions, comprehensive analysis systems and reliable services. Primary P R&D Lab Scale up Lab Quality Control Lab R&D Lab Engineering and Scale up Lab Quality Control Lab Precise instruments are the foundation of many research labs. Our high performance weighing solutions offer a basis for solid R&D results. Reliable ph meters and application specific electrodes support development tasks. Thermal analysis instruments help to improve flavors, delivery systems and materials. Automated chemistry solutions accelerate developping of new compounds. Reaction calorimeters and FTIR instruments provide sound reaction kinetics results and support reaction optimization and scale up. Particle characterization systems allow to optimize crystallizations. Quality control in relies on fast and precise analyses and safe data management to assure your products meet specifications. Balances, titrators, ph meters, density and refractometers, melting point meters, pipettes and more instruments from METTLER TOLEDO make stringent QC viable. LabX software secures data and results. 2

3 roduction Blending Filling Packaging Logistics Synthesis, Formulation Blending, Batching, Filling Packaging, Logistics We offer all sizes and formats of industrial scales with weighing terminals and software to control and monitor manufacturing processes efficiently. Specially customized solutions for formulation and numerous other applications improve productivity and eliminate human errors. Sensors and transmitters for in-line use monitor reactions. Process integrated weighing terminals optimize filling, batching and blending processes with consistent, accurate material transfers. They help minimize material waste, and increase profits. Our advanced dynamic checkweighing solutions monitor fill levels and provide automated feedback and adjustment to fillers for consistent quality and minimized product give-away. Our enhanced line of pallet, low-profile, and floor scales are suitable for daily use in dry, wet and certified hazardous areas and guarantees precision and reliability in everyday use. Products can be inspected 'in-process' or at the end of the production line for instances of foreign body contamination, inconsistent package contents and incorrect labelling. 3

4 R&D and Engineering Lab Master Tasks with Clever Solutions For Research, Development and Scale up Pushing boundaries of what is possible is essential for discoveries. METTLER TOLEDO offers innovative techniques to facilitate research and indispensable tools to manage scale up and reaction engineering. From fully automated organic synthesis to reaction calorimeters to high precision weighing and advanced materials analysis, we provide many essential lab tools for the modern scientist and engineer. Our systems help improving productivity, process reliability and safety. Get the water specifically and precisely Thermal Analysis at its Best High Precision Weighing the Fast Way Simple and secure One Click operation of Karl Fischer titrators Karl Fischer is the standard method for accurate and precise specific water content determination. Start the titrations by pressing one button only and get results within minutes. Completely closed titrator systems prevent operators from any contact with KF reagents. Coulometric method from 1 ppm to 5%. Volumetric method from 100 ppm to 100%. The universal tool for material characterization Differential scanning calorimetry (DSC) is ideal for quality control, material development and research. It determines thermal quantities, analyzes thermal processes and characterizes or compares materials. DSC yields information relating to processing, application, quality defects, identification, stability, chemical safety and purity of materials. Ultraprecise, reliable and fast weighing as an example Our analytical and microbalances offer unparalleled weighing performance with readability to as low as 0.1 μg. The ability to weigh very small quantities can result in considerable cost savings when samples are very valuable. Precision balances open the way up to 64 kg. Large platforms, robust construction and metal housings provide a long life. 4

5 Solutions for R&D and Engineering Analytical and Micro Balances Pipettes Karl Fischer Titrators Thermal Analysis Instruments: DSC, TGA In-situ FTIR Reaction Analysis Synthesis Workstations Reaction Calorimeters Bench, Compact and Floor Scales Tank Scales Analytical In- and Off-Line Sensors: ph, ORP, Conductivity, TOC Transmitters and Meters EasyMax Chemical Synthesis Made Easy Our solutions enable innovation efforts in chemistry by helping scientists invent viable synthetic routes for new compounds. By quickly evaluating various potential routes, starting materials, building blocks, and reaction conditions, chemists can safely generate the desired quantity of the target compound. Increase efficiency in organic synthesis with EasyMax and ReactIR. } 5

6 Quality Control Lab Reliable Results for Comprehensive Quality Control Getting reliable results efficiently is key for quality labs. METTLER TOLEDO is focused on providing accurate results, and offers solutions which adapt perfectly to customer requirements, make operation easier and faster and support full compliance with SOPs and regulations. Balances and analytical instruments from METTLER TOLEDO help you achieve quality targets thanks to reliable and efficient testing. One Click Titration Measuring ph, ORP and DO Pipettes and Tips to Handle Liquids Execute your titration tasks with one keystroke The Titration Excellence Line is a milestone in solutions for simple, efficient and secure titration. The unique One Click Titration provides intuitive and easy operation, maximizes efficiency and eliminates potential operator errors. User-specific short cuts can be set up on the Home Screen of the titrator to execute a task with just one keystroke. Flexible and efficient at work SevenExcellence measures ph, ion concentration, conductivity, salinity, oxidation reduction portential (ORP) and dissolved oxygen (DO). It redefines flexibility and stands for convenient operation combined with measurement accuracy, outstanding reliability and ruggedness. Benchtop meters serve to the labs. Go to the samples at any place with portable meters. A comprehensive offering Rainin pipettes enhance lab performance by guaranteeing optimum accuracy and repeatability. Innovative ergonomic designs, including the patented LTS LiteTouch System, minimize fatigue and injuries, thus reducing operator errors and inaccuracies. BioClean tips, produced under clean-room conditions, are 100% inert, preventing experiment inconsistencies and failures. 6

7 Product Solution List Potentiometric Titrators Karl Fischer Titrators Analytical Balances Precision Balances Density and Refractometers Moisture Analyzers Melting/Dropping Point Analyzers ph Meters Pipettes Thermal Analysis LabX Software FreeWeigh.Net Software Multiparameter Analysis with One Click LiquiPhysics Density and Refractometers LiquiPhyics Excellence product line offers far more than reliable instruments to measure density, specific gravity, refractive index and related values such as Brix, HFCS and Alcohol concentrations. Thanks to valuable options and accessories, the flexible LiquiPhysics systems can be automated, integrated into ERP systems and upgraded to measure color, ph or conductivity all at the same time. } 7

8 Production Synthesis Comprehensive Measuring Solutions for Production Floors Immediate control of all production steps, high operational safety level and best-in-class measurement technology are key success factors in achieving manufacturing excellence. Industrial measuring solutions from METTLER TOLEDO optimize operations and help to accelerate processes, improve product quality and comply with regulations. Secure Product Quality and Yield High Precision Weighing Process Safety and Compliance Highly reliable ph measurement in reactors In synthesis steps, whether organic or inorganic, ph is often a critical process parameter. METTLER TOLEDO ph sensors are very robust and designed to provide continuous dependable measurement performance across the widest range of process conditions. Tailor made for automation easy to integrate Our weigh modules with the electro- magnetic force restoration technology offer the highest levels of linearity and speed. They are tailored to the needs of machine and equipment manufacturers for simple electrical and mechanical integration. Improved production yield and traceability Our formulation solutions combine optimized and efficient weighing procedures along with the centralized database and relevant documentation processes, one of the prerequisite for guaranteed consistent product quality, process safety and stability as well as regulatory compliance. 8

9 Solution for Production Bench and Compact Scales Floor and Low profile Scales Tanks and Hopper Weighing Weigh Modules and Load Cells Moisture Analyzers Density and Refractometers Melting and Dropping Point ph Meters and Electrodes Potentiometric Titrators Analytical In-Line Sensors and Transmitters for ph, Conductivity and TOC Compression Weigh Modules Tank weighing Safe, Accurate, Service Friendly Liquids, powders, solids and gases are captured, stored and processed in many types of vessels, tanks, and hoppers. METTLER TOLEDO weigh modules offer rugged construction and many features for easy installation and accurate and reliable tank weighing. } 9

10 Blending/Formulation, Filling, Packaging, Logistics Solutions for Manufacturing Ensure Correct Product Quality METTLER TOLEDO provides systems and components to manage blending, formulation, filling, packaging and logistics processes efficiently, reproducibly and safely. They address the challenges of today s chemical, biotech and food additives manufacturing requirements. Our solutions support safe manufacturing steps and help to safeguard quality, safety and integrity of products, inside and out, and ensure customer satisfaction. Dynamic Checkweighing Automated fill-control with filler feedback technology Automated fill-control combined with online filler adjustment technology guarantees package fill level consistency. This ensures finished goods comply with industry regulatory requirements and legislation. Integration of other devices such as cameras, scanners, metal detectors and x-ray devices add up to a high performance inspection solution. Batch Process Control Fully integrated filling processes The IND780 batch terminal optimizes batch processes with consistent, accurate material transfers, minimizes material waste and improves batch quality. Tolerance checking, material identification via bar-code input, and operator prompting all help to ensure the operator is guided through each batch. Contaminant Detection and Integrity Checks Detect foreign particles Whether using metal detection or x-ray inspection technology, Safeline contaminant detection systems help to guarantee the safety of products. X-ray inspection systems are also able to perform a range of in-line quality checks to ensure product and pack integrity. Together they provide total product quality, inside and out. 10

11 Solutions for Blending & Filling Bench & Floor Scales Filling & Batching weighing Control Weighing Terminals Weigh Modules and Load Cells Metal Detection X-ray Inspection Vision Inspection Track & Trace Serialisation Data Management Solution IND890 Weighing Terminal Smart Filling and Blending Applications The answer's easy: "touch it"! With the standard touchscreen, the operation of the IND890 is simple and reliable even in the harshest of environments. The application terminal also sets new standards in highly complex weighing processes. It provides the perfect connection between PC and balance with powerful and reliable industrial quality - the elegant industrial weighing solution for all sectors. Application Software Apps add automated material blending. Reducing errors and making it easy to obtain process information. } 11

12 Compliance Good Measuring Practices Comply with Standards and Regulations The regulatory and legal pressure on chemicals producers is constantly increasing. Thus, manufacturers and industry organizations are forced to take even greater ownership of manufacturing processes and operational procedures. High product safety levels, safe manufacturing steps and compliance with regulations have to be achieved flawlessly. METTLER TOELDO's solutions and services provide strong support to reach these targets. Good Measuring Practices Utilize Advantages of Hygienic Design Strong Support for Tracking & Tracing Guaranteed better results through performance verification balances, scales and analytical instruments must be inspected, calibrated and tested at regular intervals to ensure the accuracy and precision of measurement results. The METTLER TOLEDO Good Measuring Practices programs provide the right tools, procedures and services and thus give peace of mind to quality, laboratory and production managers and personnel responsible for instrument qualification procedures. Contaminated processing equipment poses an immanent risk for cross contaminating products and exposing operators. Equipment must be designed according to sound sanitary design principles. Our equipment for hygienically sensitive areas is designed following the latest guidelines of EHEDG, NSF and 3-A standards and allow efficient cleaning and sanitizing, thus reducing the risk of bacteria and cross contamination. Safety regulations as well as other government and industry standards require chemical companies to assure traceability on a one-up/one-down principle. A good traceability system not only helps a manufacturer comply with legal and regulatory requirements but helps to protect brand image by minimizing the number and impact of recalls. Additionally the right systems and equipment can contribute to production efficiency through better stock management and minimized waste

13 5. Routine Operation Benefit from tangible recommendations for optimal performance verification, calibration and maintenance. 1. Evaluation Analyze your process flow and associated criteria to consistently assure the highest quality for your application and your data. 2. Selection Choose the ideal combination of instrument and measuring technology to best match your process needs. 4. Calibration & Qualification Trust the METTLER TOLEDO trained Service Team and tools when it comes to calibrating and qualifying your instruments. 3. Installation & Training Enjoy every confidence in your new device and master it with fully right from day one. Hazardous Area Explosive areas require special consideration, but performance need not be compromised. We offer a range of intrinsically safe solutions providing full safety and functionality for areas classified potentially explosive. Our ATEX, FM and IECEx certified solutions ensure compliance to legal requirements and industry standards. Equipment featuring the highest ingress protection (IP69k) to withstand wet & harsh areas is also aivailable. } 13

14 Service / Global Presence Global Services Ready for Local Reach Day-to-day laboratory and production processes are highly repetitive yet innovative, characterized by very complex applications and the need for guaranteed data quality and strict control of process risks. It is a world very sensitive to the total cost per data point, demanding the utmost precision and accuracy while constantly complying with legal and industrial regulations and norms. Uptime Performance Compliance Easy access to support knowhow and regular equipment checks according to standard procedures ensure maximum uptime at minimal cost. Your equipment is often subjected to tough environments and high utilization in critical processes, requiring every minute of uptime, guarding against equipment breakdown, parts failure, and wear and tear. Professional installation and setup of your equipment along with the use of thoroughly tested applications guarantee high performance from day one. Regular preventive maintenance according to manufacturers procedures ensures efficient and consistent performance throughout the life of your equipment, preventing out-of-spec results at all times. Full compliance with your industry's regulatory norms is a must all over the world. This ensures good audit results and provides you with peace of mind. Take advantage of our comprehensive equipment qualification and calibration packages combining standard DQ/IQ/OQ documentation with recommendations for maintenance and routine testing specific to your application. 14

15 METTLER TOLEDO is represented with Sales & Service Organizations in 36 countries as well as Distribution & Service Partners in most other countries across the globe. In total, our products and services are available in over 100 countries. Expertise Global Presence With our market organizations operating in most industrialized countries, as well as selected partners in other regions, we are ready to serve you well around the globe. Our geographically focused market organizations and partners are responsible for all aspects of sales, service and support factory-trained service and sales specialists worldwide support you. Products are developed and produced in various locations in the United States, Europe and China. Your expertise paired with the know-how of our Service Team are key to maximum uptime, optimum performance and 100% compliance. Benefit from our large portfolio of optimized applications, scientific publications, SOPs and technical documentation. In our tailored trainings and seminars, your personnel acquire the know-how and skills to run your business. 15

16 Access Information and Know-how On Application Literature We offer comprehensive application support for all of our solutions. Our application databases hold tested and proven applications for all kind of samples Webinars METTLER TOLEDO offers a wide array of live and on-demand web-based seminars (webinars). Obtain specific information about best practice and latest news on applications, products, industry trends and standards. Posters and Whitepapers Relevant information in one glimpse of an eye or diligently explained are presented by METTLER TOLEDO in posters or whitepapers For more information Mettler-Toledo AG CH-8606 Greifensee, Switzerland Tel Fax Subject to technical changes 01/2014 Mettler-Toledo AG Printed in Switzerland Global MarCom Switzerland