Greater Possibilities By Design

Transcription

1 Greater Possibilities By Design January 23, 2013 Nilam Patel MT(ASCP)SH Sr. Product Manager, Automation Solutions

2 Objectives Review current and new portfolio Technology and benefits Operational benefits Post sale support services

3 Standardized Portfolio Rapid delivery of clinical information Standardization of testing and processes Quality improvements: HSTN (Lavender Top Management ) to core lab Advanced clinical information AlphaN Reduced draw volumes / re-draws XE-5000 XT XE-2100 DM96 XS KX-21 poch-100i Intelligent Automation from satellite lab

4 Standardized Portfolio Rapid delivery of clinical information Standardization of testing and processes Quality improvements: Advanced clinical information Reduced draw volumes / re-draws HSTN AlphaN XE-5000 XE-2100 XE-5000 or XE-2100

5 Proven Foundational Technology Hydrodynamic focusing & impedance count Accurate RBC counting & sizing Measured HCT Cumulative pulse height detection Automatic floating discriminators Environmentally safe reagent- Sulfolyser-Sodium Lauryl Sulfate Dedicated channel- better HGB result and minimizes interference from: High WBC s- rare interference Mild lipemia Abnormal Proteins e.g., Multiple Myeloma

6 RNA/DNA Information Proven Fluorescent Flow Cytometry Better detection of abnormal cell types: Internal structure Cell volume RNA / DNA Provides better clinical information: 6-part differential (including IG) NRBC with auto correction of WBC and Diff (LYMPH) Internal Cell Structure

7 Total Cellular Density XE- IMI Channel Specific detector for the immature leukocytes Increased specificity for immature cells Provides enumeration of HPC (Hematopoetic Progenitor Cells) No special monoclonal antibodies or sample pretreatment Cell Volume

8 RET Channel Improved operational efficiency RET Reduced Interference From: WBCs WBC Howell Jolley Bodies RBC Parasites LFR MFR HFR Sickle cells Monitor RBC development at the IRF cellular level IRF for Retic production RET-He for iron incorporation in hemoglobin of the erythron Clinically relevant information for: Improved anemia screening and PLT monitoring of iron therapy. Reportable parameters: Ret# / %, IRF, RET-He, Optical PLT

9 Dedicated Body Fluid Analysis Automated analysis of common fluid types: Improves labor efficiencies and result accuracy Serous, synovial, CSF Automated background counts Provides cell count and 2-part diff Advanced technology- Fluorescent Flow Cytometry No sample preparations / pretreatment Accurate results from a single analysis Standardizes results Quality results Rapid TAT, labor savings

10 Comprehensive Clinical Information Reportable advanced clinical parameters- standard with XE-5000 Immature Granulocyte counts (IG %, #) Reticulocyte Hemoglobin equivalent (RET-He) Immature platelet fraction (IPF) Hematopoetic Progenitor Cell (HPC) counts

11 Sysmex Automation Solutions

12 HST-N Platform Single workstation Consolidated sample loading and unloading areas Automated smear preparations Built with standard modular components Better labor utilization System can be managed by one operator Efficient sample handling Improved efficiency and TAT Scalable to changing needs of the lab HSTN

13 Proven Slidemaker and Stainer 3rd generation product- integrated system Improves smear TAT Distinguishes STAT and routine smears Rapid, continuous flow Consistent smear quality Provides positive patient ID: 3 slide print options available Low sample volume requirements: Micro-sample port Blood aspirated and slide made when indicated SP-1000i Manual Aspiration Mode

14 Sysmex Lavender Top Management Improved Labor Efficiency: Consolidation of multiple workstations Analyzes >90% reimbursed EDTA tests Reduces sample volume requirements More testing from single draw

15 Sysmex XN-Series

16 Product Configuration Portfolio XN-1000 XN-9000 XN-2000 XN-3000

17 Clinical Utility Basic Channels Fluorescent NRBC Standard With Every XN-CBC IG with Every XN-Diff Body Fluid count with 2-part diff Advanced Channels Thrombopoiesis (IPF) Erythropoiesis (RET-He)

18 Sysmex Foundational Technology RBC & Platelet DC Detection, Hydrodynamic Focusing Hemoglobin Absorbance, Sulfolyser

19 Fluorescent Flow Cytometry WNR channel WDF channel PLT-F channel RET channel

20 PLT-F Channel RBC PLT IPF Second, reportable, platelet method Extended count time = increased count accuracy Fluorescent dye specific for platelet organelles Strong comparison with CD41/CD61 Generates reportable PLT-F & IPF Fewer manual Interventions Minimizes interference from WBC & RBC fragments and microcytic RBC s

21 XN-Series High Performance Design

22 XN Co-Primary System Fully Automated Workload Balancing Automatic re-run reflex testing

23 Compact Automation Co-primary testing modules (XN-10) Integrated slidemaker & stainer (SP-10) Automated re-run & reflex testing Convenient reagent storage

24 Scalable Automation Comprehensive clinical testing menu: Integrated slide maker & stainer- SP-10 Automated re-run reflex testing Automated load balancing workflow Scalable automation XN-9000

25 Integrated Slidemaker / Stainer 4th generation product Improves smear TAT Distinguishes STAT and routine smears Rapid, continuous flow Consistent smear quality Provides positive patient ID: 3 slide print options available Low sample volume requirements: Micro-sample port Blood aspirated and slide made when indicated SP-10

26 Scalable Sample Management XN-9000 [301] Lavender Top Management Hands-free sample management XN-TS500 XN-9000 [301]

27 Scalable Testing- HbA1c XN-9000 [301],TS-500 On-demand HbA1c testing XN-Bio-Rad VARIANT II TURBO Link XN-9000 [301], XN-TS500, XN-A1c1

28 Sysmex Lavender Top Management

29 Scalable Hematology Testing

30 Fixed Bench/Workspace XN-10 XN-10 XN-10 XN-10 Expandable Conveyor (CV-70) SP-10 Pillar Walkway Walkway Layout Accessories Options Turn Unit- XN

31 Compact Design XN-1000 XN-2000 XN w x 33.7h x 29.7d 37.8 W x 33.7h x 29.7d ~6.6 w x 3.5 h x 2.3 d XN-9000 ~ 14

32 Flexible Sample Presentation Single Aspiration Pathway Sampler Analysis (Rack) Manual Analysis (Open or Closed) No mode-to-mode QC, Comparison, Documentation Manual -Forward Position Closed tube Manual- back position Open tube Sampler(rack) Closed tube

33 Walk Away Maintenance Automated maintenance / QC rack system: Cleaning rack for shutdown QC rack for QC Automated QC rack Single button conveyor power switch

34 Low Blood Volume Usage ul (rack mode) - 60 ul (micro tube mode) 88 ul

35 Simplified Software System

36 Flexible Reagent Management Enhanced reagent management system Wireless barcode reader Concentrated reagents On-board reagent storage wagons

37 Concentrated Reagent System- Large Lab Inventory space saving Labor saving Provides more walk-away time Flexible: Packaging- 2 x 4L or 20L reagent size Connection Available for all configurations

38 Pre-Built Primary (IPU) Rules Encompass hematology best practices and guides operators to act on exception data based on: Instrument specific flags ISLH- specific criteria (Lab defined) critical value cut-offs (Lab defined) XN ACP value cut-offs (Lab-defined) patient demographic triggers: Location (Ward) Age Gender Medical record number (patient ID) Shortens implementation time

39 Operational Efficiency Gains 3 Charted result 1 Exception sample printout(s) from XN 2 Exception data review Walk-away re-run/reflex analysis Standardization of data review & decisions Standardized TAT

40 Sysmex Intelligent Automation Standardize clinical data review Advanced Rule engine

41 Advanced Rules Engine Order level rules Location, Unit, Requestor, Age, Sex, Priority Result level rules Present, outside/inside range, coded comment, flag Check previous results/orders - % or absolute Check result/absence/presence of another parameter Rerun criteria rules First run, all run, group/single tests for runs Action rules Rules to create comments, operator alerts, add/delete tests

42 Productivity Improvements Reduced manual reviews: 85% or more require no technical intervention Decrease in TAT: STATs (designated priority locations) requiring identified and displayed first Increase testing / result quality: Significant reduction in process (sample and data) errors Elimination of paper and paper handling 2 years data storage for easy access

43 Enterprise-Wide Connectivity IT Data Center LIS Clinic 1 - XS 1000i Hospital 1 - HST Hospital 2 XN-3000 Local Area Network (TCP/IP) Hospital 3 XN-9000 Oncology Center - XT2000i Clinic 2 XN-1000 Hospital 4 XN-1000

44 Standardization Across Portfolio Standardized operations Standardized reagents Standardized QC XN-1000 XN-2000 XN-3000 XN-9000

45 Reliable Systems Building On Core Strength Minimal User interaction Increased System Availability MTBF- XE-5000 (>~ 150 days) MTBF- Automation track (>~ 365 days) MTBF SP-1000i(>~ 55 days)

46 Sysmex Peak Performance SNCS Technical Service e-supply Technical Assistance Center Managed Calibration Sysmex Support Center for Learning Quality Assurance

47 Seamless Installation-SNAP SM Prior to shipment system is: Pre-assembled Pre-configured Pre-tested Significantly minimizes on-site installation time

48 Thank You