Bormioli Rocco innovation reliability premium-quality glass plastic packaging long-term expertise pharmaceutical market

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1 committed to Pharma Bormioli Rocco is recognized for innovation and outstanding reliability in premium-quality glass and plastic packaging, driven by long-term expertise in pharmaceutical market

2 Bormioli Rocco, committed to Pharma Bormioli Rocco Pharma is a premier brand in the Pharmaceutical market for glass and plastic packaging. Committed to Pharma Five production facilities dedicated to the manufacturing of high quality pharmaceutical packaging, including six furnaces for pharmaceuticals moulded and tubular glass production located in different plants, with more than 800 highly qualified employees dedicated entirely to Pharmaceutical business, are the key factors underpinning our leadership in this sector. Committed to Quality Strenuously focused on Quality, Bormioli Rocco produces in strict compliance with the highest standards of quality and safety (including GMP) and continually invests in technologies and facilities, from clean room to sophisticated control systems. Committed to Innovation R&D is a pillar of our commitment in the pharmaceutical industry: relying on our expertise we develop innovative packaging for an ever expanding range of strong cutting edge solutions that meet and anticipate the needs of the market. Our R&D center supports the client in developing customized project from concept to commercialization. Our range Our comprehensive portfolio includes child resistant and tamper evident closures, injection vials, glass and plastic bottles and accessories.

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4 Safe&Easy Main benefits for consumers and producers Clear A single partner for a complete and integrated packaging solution. Higher safety for the child The perfectly integrated design between the bottle and the plug prevents the accidental ingestion of the plug or accidental poisoning due to drug overdose of the child. Clean The system is designed to avoid liquid leakage during use, keeping the packaging perfectly clean. Application Paediatric syrup Easy The notches on the dosing syringe always remain visible during administration of the drug, ensuring a perfect reading of the dosing level of the syringe.

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6 Delta vials Main benefits for consumers and producers Superior mechanical performance Optimization in mould design, tight control of the weight and highly sophisticated technology yield a more stable, mechanically resistant, lightweight and precisely shaped vial offering a dramatic increase in processing and filling speeds on clients line. Weight reduction The great consistency in the conditioning and preparation of glass ensure a weight reduction of 30% compared to equivalent traditional vials making Delta vials an environmental friendly packaging. Superior chemical durability Delta vials prevent the phenomenon of delamination, thanks to higher initial hydrolytic resistance and internal surface homogeneity, thus increasing safety for the patient. Application Parenteral products Esthetic enhancement The optimum glass distribution and the reduction of average thickness improve the esthetic aspect.

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8 COC / COP vials Main benefits for consumers and producers Superior barrier properties To protect sensitive medicines against oxidation or water vapour, thus extending product shelf life. Sterilization The vials are suitable for autoclave and gamma sterilization. Excellent biocompatibility and low extractables The material has high purity and meets the requirements of US, EU and J Pharmacopoeia. Glass-like transparency Applications Sterilized or lyophilized products Medical and diagnostic applications Parenteral drugs High chemical and mechanical resistance The inertness of the container surface improves the drug s stability during its shelf life. In addition the vials demonstrate excellent resistance against breaks or cracks.

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10 3Phase Main benefits for consumers and producers Premium solution 3Phase represents a new revolutionary high-performance packaging solution for moisture-sensitive products. Packaging lines remain unchanged The design of the packaging remains unchanged allowing pack processing on the existing single-dose filling lines. Same administration mode of the existing single-dose Users simply have to screw on, shake and unscrew without having to modify their consumption habits. Maximization of shelf life The total moisture barrier ensures a longer lasting product integrity and effectiveness. Applications Probiotics Diet treatments Tonic treatments Cosmetics (Hair and Skin treatments) Vitamins Energy Drinks Moisture-Free Guarantee Guaranteed reliability from Bormioli Rocco, the leading sector specialist. Important sector manufacturing companies chose 3Phase as the ideal packaging for their products.

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12 Anti Counterfeit Solution Main benefits for consumers and producers Brand integrity A security taggant is incorporated in the packaging, without any visible marks on the appearance, ensuring full control of the drugs along the whole supply chain, customer s safety and brand integrity. Versatility The security taggant can be incorporated into different types of packaging (closures, plastic bottles, dosing accessories), and it offers different level of protection thanks to taggant customization. Cost-competitiveness The solution ensures competitive costs in comparison to existing technologies and allows an efficient and effective tracking of drugs along the whole supply chain. Applications Oral Ophthalmic Parenteral

13 Bormioli Rocco, a worldwide leadership Bormioli Rocco Group has five manufacturing plants dedicated to pharma packaging production and six furnaces for moulded and tubular glass production with more than 800 highly qualified employees working in its Pharmaceutical Business Unit. As a globally esteemed company, Bormioli Rocco has earned a position of leadership in this industry sector through investment in facilities, people and R&D and is fully committed to pioneering new innovative processes and launching new products to deliver higher performance and cost effectiveness.

14 Bormioli Rocco S.p.A. Viale Martiri della Libertà Fidenza - Italy tel fax packaging@bormiolirocco.com