CRANIOS REINFORCED BONE VOID FILLER

Size: px
Start display at page:

Download "CRANIOS REINFORCED BONE VOID FILLER"

Transcription

1 CRANIOS REINFORCED BONE VOID FILLER The tougher bone cement TECHNICAL MONOGRAPH

2 INTRODUCTION CRANIOS REINFORCED Bone Void Filler contains reinforcing fibers that impart an increase in toughness* to reduce crack propagation during the setting process. CRANIOS REINFORCED Bone Void Filler is a biocompatible, self-setting calcium phosphate cement intended to fill defects in the restoration or augmentation of the cranial skeleton. It contains reinforcing fibers that impart an increase in toughness* to reduce crack propagation during the setting process. CRANIOS REINFORCED Bone Void Filler also incorporates a sodium hyaluronate solution to enhance viscosity, and improve handling and injection properties. When the cement is fully cured, the composition closely approximates the mineral phase of bone. It is gradually resorbed and replaced with bone during the healing process. * Toughness is defined as a measure of a material s resistance to fracture when stressed. Data on file with DePuy Synthes Companies, mechanical test number FRN test DePuy Synthes Companies CRANIOS REINFORCED Bone Void Filler Technical Monograph

3 CRANIOS REINFORCED BONE VOID FILLER Indications CRANIOS REINFORCED Fast Set Putty and CRANIOS REINFORCED are indicated for repairing or filling cranial defects and craniotomy cuts with a surface area no larger than 25 cm². CRANIOS REINFORCED Fast Set Putty and CRANIOS REINFORCED are also indicated for the restoration or augmentation of bony contours of the cranial skeleton (including fronto-orbital areas), such as burr hole voids and other cranial defects. Contraindications CRANIOS REINFORCED Fast Set Putty and CRANIOS REINFORCED are not intended for use in the spine and should not be used in the presence of active or suspected infection. CRANIOS REINFORCED Fast Set Putty and CRANIOS REINFORCED are not for use in: patients with traumatic open injuries that are predisposed to infection stress-bearing applications, such as the temporomandibular joint areas where adjacent bone is avascular, or is incapable of supporting or anchoring the implant patients with compromised health (e.g., abnormal calcium metabolism, metabolic bone disease, a recent local untreated infection, vascular or severe neurological disease, infection, immunologic deficiencies, or systemic disorders) that result in poor wound healing or will result in tissue deterioration over the implant site patients who have not reached an age at which skull/facial growth is essentially complete defects contiguous with any of the paranasal sinuses defects greater than 25 cm 2 CRANIOS REINFORCED is not intended for use in the spine Burr hole Cranial defect Temporal bone augmentation Orbital rim Suboccipital cranioplasty Please see Directions for Use for full prescribing indications, contraindications, precautions and warnings. CRANIOS REINFORCED Bone Void Filler Technical Monograph DePuy Synthes Companies 2

4 CRANIOS REINFORCED BONE VOID FILLER CHEMICAL PROPERTIES Sodium Hyaluronate Solution Sodium hyaluronate solution is a ph-neutral viscous solution that provides enhanced mixing and flow properties for a smooth and easy application. Bioresorbable Fibers The bioresorbable poly(lactide co-glycolide) polymer fibers are randomly oriented and uniformly distributed in the material to impart an increase in toughness.* This incorporation of fibers into the matrix increases the material s resistance to cracking during the setting process. * Toughness is defined as a measure of a material s resistance to fracture when stressed. Mechanical test data on file with DePuy Synthes Companies, mechanical test number FRN test 132. Mechanical test results may not necessarily be indicative of clinical results. Calcium Phosphate Calcium phosphate has been widely used in clinical applications for decades. There are a number of publications and clinical cases available which demonstrate its safety and effectiveness to address bone regeneration.¹, ² 3 DePuy Synthes Companies CRANIOS REINFORCED Bone Void Filler Technical Monograph

5 CRANIOS REINFORCED Bone Void Filler A COMPOSITION SIMILAR TO BONE Approximation to Bone Once CRANIOS REINFORCED Bone Void Filler is fully cured, the resulting biomaterial formed is carbonated apatite, which has a crystallographic characteristic and chemical composition similar to bone. The carbonate content of carbonated apatite distinguishes CRANIOS REINFORCED Bone Void Filler from hydroxyapatite. Hydroxyapatite does not contain any carbonate; however the carbonate content of CRANIOS REINFORCED Bone Void Filler is %, which more closely resembles the composition of bone (Figure 1). CRANIOS REINFORCED Bone Void Filler CNTS/SEC Bone 2 THETA CNTS/SEC Figure 1 2 THETA CRANIOS REINFORCED Bone Void Filler Technical Monograph DePuy Synthes Companies 4

6 CRANIOS REINFORCED Bone Void Filler The tougher bone cement MECHANICAL PROPERTIES Performance in a Physiological Environment In order to set properly, CRANIOS REINFORCED Bone Void Filler requires a warm, wet environment which reduces the need to limit moisture at the operative site. The setting reaction of CRANIOS REINFORCED Bone Void Filler is isothermic, which does not cause thermal damage to the surrounding tissue. Compressive Strength As the carbonated apatite forms, the compressive strength of the material increases. In approximately 24 hours, CRANIOS REINFORCED Bone Void Filler has achieved its full compressive strength (Figure 2). Compression Load Test MPa Figure 2 CRANIOS REINFORCED Fast Set Putty CRANIOS REINFORCED Norian CRS Fast Set Putty Norian CRS HydroSet TM (Stryker ) CRANIOS REINFORCED CRANIOS REINFORCED Bone 3 Fast Set Putty Compressive Strength ~35MPa ~25MPa Cancellous Bone 5 7 MPa 5 DePuy Synthes Companies CRANIOS REINFORCED Bone Void Filler Technical Monograph

7 CRANIOS REINFORCED Bone Void Filler The tougher bone cement FIBERS INCREASE THE MATERIAL S RESISTANCE TO CRACKING Toughness* Three-point bend testing confirms CRANIOS REINFORCED Bone Void Filler to be the tougher* bone cement with an increased ability to resist cracking. Comparison of Material Toughness* CRANIOS REINFORCED Bone Void Filler Norian CRS Bone Void Filler HydroSet (Stryker) Ceramic materials are brittle in flexural loading; however, the incorporation of bioresorbable fibers into CRANIOS REINFORCED Bone Void Filler increases the material s resistance to fracture during flexural loading when compared to calcium phosphate cements without reinforcing fibers (Figure 3). Stress (MPa) Strain (mm) Figure 3 CRANIOS REINFORCED Bone Void Filler flexes but does not fail. CRANIOS REINFORCED Bone Void Filler also displayed a high Work of Fracture, which is directly related to the toughness* of the material (Figure 4). Work of Fracture Work of Fracture (J/m 2 ) CRANIOS REINFORCED Fast Set Putty CRANIOS REINFORCED Norian CRS Fast Set Putty Norian CRS HydroSet (Stryker) Figure 4 * Toughness is defined as a measure of a material s resistance to fracture when stressed. Mechanical test data on file with DePuy Synthes Companies, mechanical test number FRN test 132. Mechanical test results may not necessarily be indicative of clinical results. CRANIOS REINFORCED Bone Void Filler Technical Monograph DePuy Synthes Companies 6

8 CRANIOS REINFORCED Bone Void Filler The tougher bone cement ADDITIONAL TOUGHNESS*FOR SEVERAL MONTHS CRANIOS REINFORCED Bone Void Filler has an increased toughness* imparted by the reinforcing fibers that is sustained over a period of several months (Figure 5). When the fibers degrade, the material is equivalent in strength to the previous, Norian CRS Bone Void Filler product. Duration of Increased Toughness* 400 Work of Fracture (J/m ) CRANIOS REINFORCED Fast Set Putty Norian CRS Fast Set Putty Figure 5 Time (months) FIBERS ARE SIGNIFICANTLY RESORBED IN 12 MONTHS Fiber Resorption Over time, the reinforcing fibers begin to degrade through hydrolysis (Figure 6). The relationship between Work of Fracture and the fiber molecular weight test was determined to be directly proportional. Fiber Degradation 90,000 * Toughness is defined as a measure of a material s resistance to fracture when stressed. Mechanical test data on file with DePuy Synthes Biomaterials, mechanical test number FRN test 132. Mechanical test results may not necessarily be indicative of clinical results. Fiber Molecular Weight 80,000 CRANIOS REINFORCED Fast Set Putty 70,000 CRANIOS REINFORCED ROTARY Mix 60,000 50,000 40,000 30,000 20,000 10, Figure 6 Time (months) 7 DePuy Synthes Companies CRANIOS REINFORCED Bone Void Filler Technical Monograph

9 CRANIOS REINFORCED Bone Void Filler The tougher bone cement EASIER TO INJECT Injection For ergonomic reasons, the amount of load required to inject the material out of a syringe should be minimized. An elevated injection force may make it difficult to successfully implant the biomaterial. Each material was injected through a 12 gauge, 10 cm delivery needle (available through DePuy Synthes Companies) during the material s working time. The results of the injection test showed the amount of force required to inject both CRANIOS REINFORCED and Norian CRS to be comparable. While, in contrast, HydroSet (Stryker) required more than twice the injection force to inject (Figure 7). Injection Test Peak Load 35 Peak Load (lbf) CRANIOS REINFORCED Norian CRS HydroSet (Stryker) Figure 7 CRANIOS REINFORCED Bone Void Filler Technical Monograph DePuy Synthes Companies 8

10 PRODUCT INFORMATION CRANIOS REINFORCED Fast Set Putty, sterile CRANIOS REINFORCED, sterile S 3 cc S 3 cc S 5 cc S 5 cc S 10 cc S 10 cc Delivery Needles, sterile MXR-US-2000 er S S S S 8 gauge x 10 cm, 1/pkg. 10 gauge x 10 cm, 1/pkg. 10 gauge x 10 cm, 5/pkg. 12 gauge x 10 cm, 1/pkg. 9 DePuy Synthes Companies CRANIOS REINFORCED Bone Void Filler Technical Monograph

11 REFERENCES 1. Cassidy C, Jupiter JB, Cohen M, Delli-Santi M, Fennell C, Leinberry C, et al. Norian SRS cement compared with conventional fixation in distal radial fractures. A randomized study. J Bone Joint Surg Am Nov;85-A: Chang BS, Lee CK, Hong KS, Youn HJ, Ryu HS, Chung SS, et al. Osteoconduction at porous hydroxyapatite with various pore configurations. Biomaterials. 2000;21: Cowin, SC, ed. Bone Mechanics Handbook, 2nd ed. New York, NY: RC Press, CRANIOS REINFORCED Bone Void Filler Technical Monograph DePuy Synthes Companies 10

12 Limited Warranty and Disclaimer: DePuy Synthes Biomaterials products are sold with a limited warranty to the original purchaser against defects in workmanship and materials. Any other express or implied warranties, including warranties of merchantability or fitness, are hereby disclaimed. WARNING: In the USA, this product has labeling limitations. See package insert for complete information. CAUTION: USA Law restricts these devices to sale by or on the order of a physician. Not all products are currently available in all markets. Manufactured by (United States): Synthes USA Products, LLC 1302 Wrights Lane East West Chester, PA Telephone: (610) To order: (800) Fax: (610) DePuy Synthes All rights reserved. Norian and SRS are trademarks of DSM Biomedical or its affiliates. Stryker Orthopaedics and HydroSet are trademarks of Stryker Corp. or its affiliates. DSUS/MOC/1214/ /15 DV

NORIAN DRILLABLE TECHNICAL MONOGRAPH. Fiber reinforced calcium phosphate phate bone void filler

NORIAN DRILLABLE TECHNICAL MONOGRAPH. Fiber reinforced calcium phosphate phate bone void filler NORIAN DRILLABLE Fiber reinforced calcium phosphate phate bone void filler TECHNICAL MONOGRAPH INDICATIONS & CONTRAINDICATIONS Drillable Drillable is intended for bony voids or defects of the extremities

More information

HydroSet. Injectable HA Bone Substitute

HydroSet. Injectable HA Bone Substitute HydroSet Injectable HA Bone Substitute The Latest Advancement in Bone Substitute Technology Fast Setting Injectable or Manual Implantation Osteoconductive Excellent Wet-field Characteristics Isothermic

More information

FORWARD-LOOKING STATEMENTS

FORWARD-LOOKING STATEMENTS FORWARD-LOOKING STATEMENTS The statements made by Kensey Nash and its representatives in this presentation will include certain forward-looking statements, including financial forecasts, that are based

More information

MIIG INJECTABLE Graft The following languages are included in this packet:

MIIG INJECTABLE Graft The following languages are included in this packet: MIIG INJECTABLE Graft 128801-10 The following languages are included in this packet: English (en) Deutsch (de) Nederlands (nl) Français (fr) Español (es) Italiano (it) Português (pt) 中文 - Chinese (sch)

More information

strength of science Now with sizes up to 25 cm x 45 cm XCM BIOLOGIC Tissue Matrix

strength of science Now with sizes up to 25 cm x 45 cm XCM BIOLOGIC Tissue Matrix strength of science XCM BIOLOGIC Tissue Matrix Now with sizes up to 25 cm x 45 cm Your trusted partner providing a complete portfolio of biologic meshes. DePuy Synthes Companies of Johnson & Johnson offer

More information

RAPIDSORB Injectable Polymer System (IPS) Surgical Technique

RAPIDSORB Injectable Polymer System (IPS) Surgical Technique RAPIDSORB Injectable Polymer System (IPS) Surgical Technique TABLE OF CONTENTS INTRODUCTION RAPIDSORB Injectable Polymer System (IPS) 2 Indications and Contraindications 4 SURGICAL TECHNIQUE Preparation

More information

RAPIDSORB Injectable Polymer System (IPS) Surgical Technique

RAPIDSORB Injectable Polymer System (IPS) Surgical Technique RAPIDSORB Injectable Polymer System (IPS) Surgical Technique TABLE OF CONTENTS INTRODUCTION RAPIDSORB Injectable Polymer System (IPS) 2 Indications and Contraindications 4 SURGICAL TECHNIQUE Preparation

More information

Ceramic Biomaterials. Lecture #17

Ceramic Biomaterials. Lecture #17 Ceramic Biomaterials Lecture #17 Ceramics Refractory (maintain shape and composition at high temperatures) Polycrystalline Nonductile virtually zero creep at room temperatures Usually inorganic Silicates

More information

INSTRUCTIONS FOR USE FOR:

INSTRUCTIONS FOR USE FOR: INSTRUCTIONS FOR USE FOR: en English INSTRUCTIONS FOR USE GORE ENFORM INTRAPERITONEAL BIOMATERIAL Carefully read all instructions prior to use. Observe all instructions, warnings, and precautions noted

More information

CONTINUED COMMITMENT. A Complete Portfolio of Services for You and Your Practice

CONTINUED COMMITMENT. A Complete Portfolio of Services for You and Your Practice CONTINUED COMMITMENT A Complete Portfolio of Services for You and Your Practice PROMOTIONAL SUPPORT EDUCATIONAL RESOURCES DIRECT ACCESS ADDITIONAL SERVICES PROMOTIONAL SUPPORT We can help market the TPLO

More information

MEDPOR. Orbital Floor

MEDPOR. Orbital Floor MEDPOR Orbital Floor Orbital Fracture Repair Available in a variety of shapes, sizes, and configurations, MEDPOR and MEDPOR TITAN Implants provide surgeons with an expanding range of options for reconstruction

More information

RapidPort EZ Access Port Kit DIRECTIONS FOR USE (DFU)

RapidPort EZ Access Port Kit DIRECTIONS FOR USE (DFU) RapidPort EZ Access Port Kit DIRECTIONS FOR USE (DFU) RapidPort EZ Access Port Kit Ref. No. C-2304 Standard RapidPort EZ Access Port Kit Ref. No. C-2306 Large RapidPort EZ Access Port Kit INTRODUCTION

More information

PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE

PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE 137835-5 The following languages are included in this packet: English (en) For additional information please contact the manufacturer

More information

PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE

PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE PRO-STIM Injectable Inductive Graft Containing DONATED HUMAN TISSUE 150842-0 The following languages are included in this packet: English (en) For additional information please contact the manufacturer

More information

Trabecular Metal Technology

Trabecular Metal Technology Trabecular Metal Technology Alexandre Nehme Departement of Orthopedic Surgery. Saint Georges University Hospital. Beirut. The cellular structure of Tantallum (Trabecular Metal) resembles bone and approximates

More information

PEEK-OPTIMA HA ENHANCED. Advancing the Science of Fusion

PEEK-OPTIMA HA ENHANCED. Advancing the Science of Fusion HA ENHANCED Advancing the Science of Fusion Two clinically proven biomaterials, together in one innovative compound. Hydroxyapatite (HA), a well-known osteoconductive material that enhances bone apposition,

More information

INSTRUCTIONS FOR USE FOR:

INSTRUCTIONS FOR USE FOR: INSTRUCTIONS FOR USE FOR: B I O M A T E R I A L en English INSTRUCTIONS FOR USE FOR GORE SYNECOR INTRAPERITONEAL BIOMATERIAL INDICATIONS The GORE SYNECOR Intraperitoneal Biomaterial device is intended

More information

Ceramics, Glasses, and Glass-Ceramics

Ceramics, Glasses, and Glass-Ceramics Ceramics, Glasses, and Glass-Ceramics Ceramics, Glasses, and Glass-Ceramics include a broad range of inorganic/nonmetallic compositions. Eyeglasses Diagnostic instruments Thermometers Tissue culture flasks

More information

We ve built a STRONG CASE. for changing the way you sterilize. Reusable Sterilization Container System

We ve built a STRONG CASE. for changing the way you sterilize. Reusable Sterilization Container System We ve built a STRONG CASE for changing the way you sterilize. Reusable Sterilization Container System Reusable Sterilization Container System Introducing the DePuy Synthes REUSABLE STERILIZATION CONTAINER

More information

LAP-BAND System Access Port II Kit

LAP-BAND System Access Port II Kit LAP-BAND System Access Port II Kit DIRECTIONS FOR USE (DFU) Access Port Needle Access Port Priming Needle Access Port II End Plug Band Priming Needle Stainless Steel Connector Tubing LAP-BAND System Access

More information

A Legacy of Serving the Surgical Community

A Legacy of Serving the Surgical Community Precisely. A Legacy of Serving the Surgical Community For over half a century, Stryker has been developing products based on the expressed needs of leading practitioners. You will often find a Stryker

More information

CapSure Permanent Fixation System

CapSure Permanent Fixation System CapSure Permanent Fixation System Permanent Fixation Redefined Advancing the Fixation Experience Recipient of 2015 SLS Innovations of the Year recognition. SOFT TISSUE REPAIR Right Procedure. Right Product.

More information

Calzada Ltd. ASX:CZD Investor Overview September 2011

Calzada Ltd. ASX:CZD Investor Overview September 2011 Calzada Ltd ASX:CZD Investor Overview September 2011 Disclaimer This presentation is provided for general information purposes only. It is not intended to be relied upon as advice and does not take into

More information

CAUTION: U.S. Federal law restricts this device to sale by or on the order of a licensed physician.

CAUTION: U.S. Federal law restricts this device to sale by or on the order of a licensed physician. TM CAUTION: U.S. Federal law restricts this device to sale by or on the order of a licensed physician. TABLE OF CONTENTS Section Port Styles 4 Description 5 Indications 5 Contraindications 5-6 Information

More information

Forefoot. Foot & Ankle. Foot & Ankle. Midfoot. Bone Graft Substitutes Soft Tissue Repair. Rearfoot. Ankle

Forefoot. Foot & Ankle. Foot & Ankle. Midfoot. Bone Graft Substitutes Soft Tissue Repair. Rearfoot. Ankle Forefoot Foot & Ankle Midfoot Rearfoot Foot & Ankle Bone Graft Substitutes Soft Tissue Repair Ankle Vitoss Vitoss is the #1 selling Synthetic Bone Graft for one good reason... IT WORKS. 1 Human clinical

More information

Biomaterials. Third Edition

Biomaterials. Third Edition Biomaterials Third Edition Joon Park R.S. Lakes Biomaterials An Introduction Third Edition Joon Park Biomedical and Mechanical Engineering University of Iowa Iowa City, IA 52242-1414 USA joon-park@uiowa.edu

More information

Ventrio ST Hernia Patch featuring Sepra Technology

Ventrio ST Hernia Patch featuring Sepra Technology Ventrio ST Hernia Patch featuring Sepra Technology Sepra Technology An extensively studied barrier with more than 10 publications and used clinically since 2007. Unique hydrogel barrier swells to minimize

More information

Functionally stratified design and manufacture of hip and knee joints

Functionally stratified design and manufacture of hip and knee joints Functionally stratified design and manufacture of hip and knee joints is to develop and deliver new simulation methods for the design and manufacture of hip and knee prostheses, to be evaluated through

More information

Personnel Protection Vehicle Protection Structural Protection

Personnel Protection Vehicle Protection Structural Protection S-2 Glass Armor Systems Personnel Protection Vehicle Protection Structural Protection Hit Us With Your Best Shot From military rocket motor housings to combat vehicle hulls and from composite inserts for

More information

AVIMID N POLYIMIDE COMPOSITE

AVIMID N POLYIMIDE COMPOSITE DESCRIPTION AVIMID N is a high temperature, post-curable, 775 F (413 C) Tg* thermoplastic polyimide composite with wet service capability up to 630 F (332 C) and dry service capability of 700 F (370 C).

More information

The advantages and use of ceramics in medicine

The advantages and use of ceramics in medicine The advantages and use of ceramics in medicine G. Carl Friedrich-Schiller-Universität Jena Otto-Schott-Institut (now with JSJ Jodeit GmbH Jena) ORTHOSONIC CERAMIC CONFERENCE Saturday 6 th July 2002 bioceramics

More information

AIT/Athlone Institute of Technology

AIT/Athlone Institute of Technology Technology Complete denomination: Higher Education Institute Location (city, country): Athlone, Ireland President: Prof.Ciaran O Cathain GENERAL PRESENTATION Contact person in NEWGEN: Dr. Declan Devine:

More information

Advancing the Open Ventral Hernia Repair Experience

Advancing the Open Ventral Hernia Repair Experience Advancing the Open Ventral Hernia Repair Experience SOFT TISSUE REPAIR Right Procedure. Right Product. Right Outcome. Hernia Repair Fixation Absorbable Fixation System Optimized Design for Open Ventral

More information

Bone Fractures and Engineering (lesson)

Bone Fractures and Engineering (lesson) See how this example filled-in lesson template looks on the TeachEngineering website: http://www.teachengineering.org/view_lesson.php?url=collection/cub_/lessons/cub_biomed/cub_biomed_lesson10.xml Bone

More information

The information contained in this document is intended for healthcare professionals only.

The information contained in this document is intended for healthcare professionals only. The information contained in this document is intended for healthcare professionals only. Orthopaedics Modular Taper Junction and Neck Strength in Total Hip Arthroplasty Re s tora ti on Modular Revi s

More information

HANDLING OF WRIGHT MEDICAL DISPOSABLE PROPHECY TM ANKLE INSTRUMENTS

HANDLING OF WRIGHT MEDICAL DISPOSABLE PROPHECY TM ANKLE INSTRUMENTS HANDLING OF WRIGHT MEDICAL DISPOSABLE PROPHECY TM ANKLE INSTRUMENTS 153290-0 The following languages are included in this packet: English (en) For additional languages, visit our website www.wright.com

More information

B i o m a t e r i a l s E n g i n e e r i n g

B i o m a t e r i a l s E n g i n e e r i n g B i o m a t e r i a l s E n g i n e e r i n g Collagen, a key factor for clinical success INTRODUCTION A REVOLUTIONARY INNOVATION Tecnoss exclusive manufacturing process is able to neutralize the antigenic

More information

In Vitro and In Vivo Comparison of New Biodegradable Magnesium-Based Implants for Orthopedic Uses.

In Vitro and In Vivo Comparison of New Biodegradable Magnesium-Based Implants for Orthopedic Uses. In Vitro and In Vivo Comparison of New Biodegradable Magnesium-Based Implants for Orthopedic Uses. Olga Charyeva, DDS 1, Ulrich Thormann, Dr. 2, Sven Schmidt, Dr. 2, Lydia Heimann 3, Ursula Sommer, Dr.

More information

Investigation of Mechanical Properties of CFRP/EVA Laminated Composites According to Tensile and Flexure Test

Investigation of Mechanical Properties of CFRP/EVA Laminated Composites According to Tensile and Flexure Test Investigation of Mechanical Properties of CFRP/EVA Laminated Composites According to and Flexure Test SUN-HO GO 1, SEONG-MIN YUN 1, MIN-SANG LEE 1, JANG-HO LEE 3, LEE-KU KWAC 4, # HONG-GUN KIM 4 1 Graduate

More information

Tissue Engineered Medical Products

Tissue Engineered Medical Products WORKSHOP 8 Tissue Organizer: Jeremy J. Rawlinson PhD Speakers: Jack E. Lemons, PhD Lawrence J. Bonassar, PhD Mauro R. Alini, PhD Michael J. Yaszemski, MD, PhD Standards for Tissue J. Lemons, University

More information

RESPIRATORY SENSING LEAD

RESPIRATORY SENSING LEAD RESPIRATORY SENSING LEAD 4340 Technical Manual ONLY Explanation of symbols on product or package labeling Caution, consult accompanying documents eifu indicator Consult electronic instructions for use

More information

Trabecular Metal Revision Shell. Surgical Technique IMAGE TO COME. The Best Thing Next to Bone

Trabecular Metal Revision Shell. Surgical Technique IMAGE TO COME. The Best Thing Next to Bone Trabecular Metal Revision Shell Surgical Technique IMAGE TO COME The Best Thing Next to Bone Trabecular Metal Revision Shell Surgical Technique Initial and Long-Term Stability Fully-interconnected trabecular

More information

More than surface deep

More than surface deep Tritanium PL Posterior Lumbar Cage More than surface deep Featuring Tritanium In-Growth Technology: 1 TM Built to fuse Tritanium In-Growth Technology1 Stryker s proprietary Tritanium In-Growth Technology,

More information

European Standard En 1504

European Standard En 1504 BS EN 1504 Products and Systems for the protection and repair of concrete structures Definitions, requirements, quality control and evaluation of conformity John Drewett Concrete Repairs Ltd 25% of the

More information

Synthetic Bioabsorbable Polymers for Implants

Synthetic Bioabsorbable Polymers for Implants STP 1396 Synthetic Bioabsorbable Polymers for Implants C. Mauli Agrawal, Jack E. Parr, and Steve T. Lin, editors ASTM Stock Number: STP1396 ASTM 100 Barr Harbor Drive PO Box C700 West Conshohocken, PA

More information

Entellus Medical Sinuscope INSTRUCTIONS FOR USE

Entellus Medical Sinuscope INSTRUCTIONS FOR USE Entellus Medical Sinuscope INSTRUCTIONS FOR USE Table of contents Entellus Medical Sinuscope Instructions for Use 1. About this document... 1 1.1 Purpose... 1 1.2 Symbols used... 1 2. Intended use... 2

More information

Madewell Products Corporation December Industrial Court Alpharetta, GA Office: (770) Fax: (770)

Madewell Products Corporation December Industrial Court Alpharetta, GA Office: (770) Fax: (770) Madewell Products Corporation December 2014 7561 Industrial Court Alpharetta, GA 30004 Office: (770) 475-8199 Fax: (770) 475-8167 PART 1 GENERAL Product Guide Specification SECTION 03935 SPRAYABLE MICROSILICA

More information

NEXT GENERATION ECM-BASED ALLOGRAFT TECHNOLOGY:

NEXT GENERATION ECM-BASED ALLOGRAFT TECHNOLOGY: NEXT GENERATION ECM-BASED ALLOGRAFT TECHNOLOGY: Potent biological scaffolds strategically control stem cell fate and function, allowing our allografts to harness the regenerative potential of patient s

More information

DuraGen Secure. Dural Regeneration Matrix

DuraGen Secure. Dural Regeneration Matrix DuraGen Secure Dural Regeneration Matrix DESCRIPTION DuraGen Secure Dural Regeneration Matrix is an absorbable implant for the repair of dural defects. DuraGen Secure Dural Regeneration Matrix is an easy

More information

EGN 3365 Review on Metals, Ceramics, & Polymers, and Composites by Zhe Cheng

EGN 3365 Review on Metals, Ceramics, & Polymers, and Composites by Zhe Cheng EGN 3365 Review on Metals, Ceramics, & Polymers, and Composites 2017 by Zhe Cheng Expectations on Chapter 11 Chapter 11 Understand metals are generally categorized as ferrous alloys and non-ferrous alloys

More information

FINAL TECHNICAL REPORT November 1, 1998, through October 31, Project Title: EXTRUDED FIBER-REINFORCED CEMENT COMPOSITES CONTAINING FLY ASH

FINAL TECHNICAL REPORT November 1, 1998, through October 31, Project Title: EXTRUDED FIBER-REINFORCED CEMENT COMPOSITES CONTAINING FLY ASH FINAL TECHNICAL REPORT November 1, 1998, through October 31, 1999 Project Title: EXTRUDED FIBER-REINFORCED CEMENT COMPOSITES CONTAINING FLY ASH ICCI Project Number: Principal Investigator: Other Investigators:

More information

paper tech Unique Flexible Epoxy Systems for Flooring and Secondary Containment Leo Meilus EPIKOTE EPON EPI-CURE EPI-REZ HELOXY CARDURA VEOVA

paper tech Unique Flexible Epoxy Systems for Flooring and Secondary Containment Leo Meilus EPIKOTE EPON EPI-CURE EPI-REZ HELOXY CARDURA VEOVA tech paper SC:2227-01 Unique Flexible Epoxy Systems for Flooring and Secondary Containment By Leo Meilus EPIKOTE EPON EPI-CURE EPI-REZ HELOXY CARDURA VEOVA SC:2227-01 / Unique Flexible Epoxy Systems for

More information

References. One Surgeon. One Patient. FLM /08

References. One Surgeon. One Patient. FLM /08 FLM 196 06/08 References 1. Biomet Biomaterials Laboratory The revolutionary second generation vitamin E stabilsed highlycrosslinked UHMWPE Jan 2007. 2. Wannomnnomae, K. Environmental Stress Cracking of

More information

NeuroPort Array PN 4382, 4383, 6248, and 6249 Instructions for Use

NeuroPort Array PN 4382, 4383, 6248, and 6249 Instructions for Use 630 Komas Drive Suite 200 Salt Lake City UT 84108 USA P +1 801.582.5533 F +1 801.582.1509 www.blackrockmicro.com NeuroPort Array PN 4382, 4383, 6248, and 6249 Instructions for Use Revision 2.00 / LB-0612

More information

Commercial: Active Africa & Middle East Asia Pacific Glass\Mineral, 65% Filler by Weight Heat Stabilizer

Commercial: Active Africa & Middle East Asia Pacific Glass\Mineral, 65% Filler by Weight Heat Stabilizer Technical Data Amodel AS-1566 HS polyphthalamide Amodel AS-1566 HS resin is a 65% glass and mineral reinforced polyphthalamide (PPA) resin that exhibits a high deflection temperature and high flexural

More information

Repliform. Tissue Regeneration Matrix. Instructions for Use. Distributed by:

Repliform. Tissue Regeneration Matrix. Instructions for Use. Distributed by: Repliform Tissue Regeneration Matrix Instructions for Use Distributed by: Boston Scientific Corporation 300 Boston Scientific Way Marlborough, MA 01752 Processed from Donated Human Tissue by: LifeCell

More information

This document is a preview generated by EVS

This document is a preview generated by EVS INTERNATIONAL STANDARD ISO 13175-3 First edition 2012-10-01 Implants for surgery Calcium phosphates Part 3: Hydroxyapatite and beta-tricalcium phosphate bone substitutes Implants chirurgicaux Phosphates

More information

Amodel AS-1133 HS. polyphthalamide. Technical Data Sheet

Amodel AS-1133 HS. polyphthalamide. Technical Data Sheet Technical Data Sheet Amodel AS-1133 HS Amodel AS-1133 HS is a 33% glass reinforced, heat stabilized (PPA) resin that provides excellent structural integrity in molded parts, even those with wall thicknesses

More information

White Paper: Designing Functional Fabrics for Today s Heart Valves and Beyond

White Paper: Designing Functional Fabrics for Today s Heart Valves and Beyond White Paper: Designing Functional Fabrics for Today s Heart Valves and Beyond Ryan Heniford Business Development Director Peter Gabriele Director, Emerging Technology How fabrics can be used in heart valves,

More information

Commercial: Active Africa & Middle East Asia Pacific

Commercial: Active Africa & Middle East Asia Pacific Technical Data Sheet AvaSpire AV-651 is an unreinforced (PAEK) that offers more ductility and impact strength than PEEK, with higher chemical and environmental stress cracking resistance than AvaSpire

More information

Keywords: super absorbent polymers, self-healing, green construction technology

Keywords: super absorbent polymers, self-healing, green construction technology Autonomous Repair in Cementitous Material by Combination of Superabsorbent Polymers and Polypropylene Fibres: A Step Towards Sustainable Infrastructure Souradeep GUPTA a, KUA Harn-wei b, PANG Sze-dai c

More information

EasyClip Xpress Sterile staple solution. Operative technique

EasyClip Xpress Sterile staple solution. Operative technique EasyClip Xpress Sterile staple solution Operative technique Sterile staple solution Table of contents Indications 3 Operative technique 4 This publication sets forth detailed recommended procedures for

More information

DIVISION 3 - CONCRETE Section Concrete Toppings Section Concrete Resurfacing Section Concrete Rehabilitation

DIVISION 3 - CONCRETE Section Concrete Toppings Section Concrete Resurfacing Section Concrete Rehabilitation Spec Component: SC-025-03/10 SikaTop 122 Plus DIVISION 3 - CONCRETE Section 03550 - Concrete Toppings Section 03720 - Concrete Resurfacing Section 03730 - Concrete Rehabilitation Part 1 General 1.01 Summary

More information

Effect of Sintering Temperature Rate on Physical Properties of Porous Tricalcium Phosphate (TCP) Ceramics

Effect of Sintering Temperature Rate on Physical Properties of Porous Tricalcium Phosphate (TCP) Ceramics Effect of Sintering Temperature Rate on Physical Properties of Porous Tricalcium Phosphate (TCP) Ceramics Ahmad Fadli 1, Abdul Rasyid 1 *, Ricky Firmansyah 1 1 Jln. HR. Subrantas Km. 12,5. Department of

More information

Project Proposal Ultrasound Mediated Tissue Engineering Project Team 21

Project Proposal Ultrasound Mediated Tissue Engineering Project Team 21 Project Proposal Ultrasound Mediated Tissue Engineering Project Team 21 Nicholas Calistri, Aimon Iftikhar, Yvonne Nanakos and Kelly Stratton Project 40 for Dr. Yusuf Khan University of Connecticut Health

More information

Short Aramid Fibre Reinforced Ultra-High Molecular Weight Polyethylene Composite. A new hip-prosthesis Hofsté, Joanna Maria

Short Aramid Fibre Reinforced Ultra-High Molecular Weight Polyethylene Composite. A new hip-prosthesis Hofsté, Joanna Maria University of Groningen Short Aramid Fibre Reinforced Ultra-High Molecular Weight Polyethylene Composite. A new hip-prosthesis Hofsté, Joanna Maria IMPORTANT NOTE: You are advised to consult the publisher's

More information

profile-mix-plus, Page 1 of 8, Rev

profile-mix-plus, Page 1 of 8, Rev Strong-Seal Profile Mix for reconstructing deteriorated structures to original dimensions, eliminating infiltration and providing structural restoration, corrosion protection and a smooth surface for application

More information

How do we find ultimate properties?

How do we find ultimate properties? Introduction Why ultimate properties? For successful product design a knowledge of the behavior of the polymer is important Variation in properties over the entire range of operating conditions should

More information

Composite Repairs for Pipelines

Composite Repairs for Pipelines ABN 69 003 696 526 Composite Repairs for Pipelines TGN-W-01 Rev: 0 Date: 1 March 2006 Pages: 5 1. SCOPE This document provides an introduction to the use of composite materials as a methodology for repairing

More information

Guide for Cleaning, Sterilization and Storage of Reusable Introducers

Guide for Cleaning, Sterilization and Storage of Reusable Introducers Guide for Cleaning, Sterilization and Storage of Reusable Introducers M Manufactured by: Caldera Medical, Inc. 5171 Clareton Drive Agoura Hills, CA 91301 U.S. Toll Free: 866-4-CALDERA Telephone: 818-879-6555

More information

Commercial: Active Africa & Middle East Asia Pacific Glass Fiber, 50% Filler by Weight Flame Retardant. Physical Typical Value Unit Test method

Commercial: Active Africa & Middle East Asia Pacific Glass Fiber, 50% Filler by Weight Flame Retardant. Physical Typical Value Unit Test method Technical Data Sheet Ixef 1521 Ixef 1521 is a 50% glass-fiber reinforced, flame retardant which exhibits high strength and stiffness, outstanding surface gloss, and excellent creep resistance. Custom Colorable

More information

Empowering innovation.

Empowering innovation. Empowering innovation. RESOMER is a synonym for innovation and vision, enabling both pharma and medical device companies to shape and design a better future. 30 years of RESOMER The history of RESOMER

More information

Investigating the Mechanical Behaviors of Organic/Inorganic Composite Bone Scaffolds

Investigating the Mechanical Behaviors of Organic/Inorganic Composite Bone Scaffolds University of Arkansas, Fayetteville ScholarWorks@UARK Biomedical Engineering Undergraduate Honors Theses Biomedical Engineering 5-2016 Investigating the Mechanical Behaviors of Organic/Inorganic Composite

More information

VAPR VUE RADIOFREQUENCY SYSTEM, WITH COOLPULSE TECHNOLOGY

VAPR VUE RADIOFREQUENCY SYSTEM, WITH COOLPULSE TECHNOLOGY VAPR VUE RADIOFREQUENCY SYSTEM, WITH COOLPULSE TECHNOLOGY Differentiation That Matters: So You Can Ablate Efficiently, Yet Safely The next generation in arthroscopic radiofrequency ablation SHOULDER /

More information

Araldite MT FST Benzoxazine Resin

Araldite MT FST Benzoxazine Resin Advanced Materials Araldite MT 35710 FST Benzoxazine Resin PRELIMINARY DATA SHEET Key Properties Low fire, smoke and toxicity (FST) properties Volatile/void free during curing High resin modulus and strength

More information

Ultraporous Acetabular Surfaces are Needed PRO

Ultraporous Acetabular Surfaces are Needed PRO Ultraporous Acetabular Surfaces are Needed PRO Wayne G. Paprosky, MD, FACS Medical Director, Cadence Health Joint Replacement Institute Central DuPage Hospital Professor RUSH University Medical Center

More information

Production and commercialisation of vascularized and customized bone Clinical trials, market authorisation Pre-clinical trials

Production and commercialisation of vascularized and customized bone Clinical trials, market authorisation Pre-clinical trials Production and commercialisation of vascularized and customized bone Clinical trials, market authorisation Pre-clinical trials Basic Research: scaffolds, cells/ media, in vivo imaging, modelling www.vascubone.eu

More information

MS-2A LINER SPECIFICATIONS: for STRUCTURAL REPAIR and SEALING of MANHOLES

MS-2A LINER SPECIFICATIONS: for STRUCTURAL REPAIR and SEALING of MANHOLES MS-2A LINER SPECIFICATIONS: for STRUCTURAL REPAIR and SEALING of MANHOLES INTENT: To provide a system for reconstruction of concrete or masonry structures to stop inflow, infiltration, exfiltration, and

More information

Performance Purity Flexibility Endurance

Performance Purity Flexibility Endurance Invibio Inc 3A Caledon Court. Greenville, SC 29615. USA Tel: 866-INVIBIO (866-468-4246). Fax: (864) 672-7328 Invibio Ltd Technology Centre. Hillhouse International Thornton Cleveleys. Lancashire. FY5 4QD.

More information

Multi-scale Performance and Durability of Carbon Nanofiber/Cement Composites Florence Sanchez, Ph.D. Lu Zhang, Ph.D. Chantal Ince

Multi-scale Performance and Durability of Carbon Nanofiber/Cement Composites Florence Sanchez, Ph.D. Lu Zhang, Ph.D. Chantal Ince Multi-scale Performance and Durability of Carbon Nanofiber/Cement Composites Florence Sanchez, Ph.D. Lu Zhang, Ph.D. Chantal Ince Civil and Environmental Engineering Motivation Increase interest in multi-functional,

More information

Mechanical Characterization and Stimulation Solutions for Biomaterials

Mechanical Characterization and Stimulation Solutions for Biomaterials Mechanical Characterization and Stimulation Solutions for Biomaterials BioDynamic Instruments Biomaterials and Tissue Characterization Application Examples Bone Bending Creep Test Clinical Need: Understand

More information

COMPOSITE CARBON FIBRE EMBEDMENT DEPTH AND ANGLE CONFIGURATION INFLUENCE ON SINGLE FIBRE PULL-OUT FROM CONCRETE

COMPOSITE CARBON FIBRE EMBEDMENT DEPTH AND ANGLE CONFIGURATION INFLUENCE ON SINGLE FIBRE PULL-OUT FROM CONCRETE COMPOSITE CARBON FIBRE EMBEDMENT DEPTH AND ANGLE CONFIGURATION INFLUENCE ON SINGLE FIBRE PULL-OUT FROM CONCRETE Arturs Lukasenoks, Arturs Macanovskis, Andrejs Krasnikovs Riga Technical University, Latvia

More information

Price and Availability

Price and Availability Price and Availability Outline Introduction Relative cost of materials Example MECH 321 Mech. Eng. Dept. - Concordia University lecture 21/1 Current Prices on the web (a) : - Short term trends: fluctuations

More information

Madewell Products Corporation December Industrial Court Alpharetta, GA Office: (770) Fax: (770)

Madewell Products Corporation December Industrial Court Alpharetta, GA Office: (770) Fax: (770) Madewell Products Corporation December 2014 7561 Industrial Court Alpharetta, GA 30004 Office: (770) 475-8199 Fax: (770) 475-8167 Product Guide Specification SECTION 03935 RESTORATION MORTAR AND EPOXY

More information

A PVA_PCL_Bioglass Composite with Potential Implications for Osteochondral Tissue Engineering.

A PVA_PCL_Bioglass Composite with Potential Implications for Osteochondral Tissue Engineering. A PVA_PCL_Bioglass Composite with Potential Implications for Osteochondral Tissue Engineering. Journal: 2009 MRS Fall Meeting Manuscript ID: Draft Symposium: Symposium RR Date Submitted by the Author:

More information

Commercial: Active Africa & Middle East Asia Pacific. RoHS Compliant Beige Pellets Extrusion Blow Molding Fiber (Spinning) Extrusion Film Extrusion

Commercial: Active Africa & Middle East Asia Pacific. RoHS Compliant Beige Pellets Extrusion Blow Molding Fiber (Spinning) Extrusion Film Extrusion Technical Data Sheet AvaSpire AV-621 is an unreinforced (PAEK) that offers improved ductility and impact strength relative to PEEK while retaining most of the key performance attributes of PEEK. The AV-621

More information

Division 3 - Concrete Section Concrete Rehabilitation

Division 3 - Concrete Section Concrete Rehabilitation Spec Component: SC-039-03/10 Sikadur 23, Lo-Mod Gel Division 3 - Concrete Section 03930 - Concrete Rehabilitation Part 1 - General 1.01 Summary A. This specification describes the patching of exterior

More information

Commercial: Active Africa & Middle East Asia Pacific. RoHS Compliant Beige Pellets Extrusion Blow Molding Fiber (Spinning) Extrusion Film Extrusion

Commercial: Active Africa & Middle East Asia Pacific. RoHS Compliant Beige Pellets Extrusion Blow Molding Fiber (Spinning) Extrusion Film Extrusion Technical Data Sheet AvaSpire AV-621 is an unreinforced (PAEK) that offers improved ductility and impact strength relative to PEEK while retaining most of the key performance attributes of PEEK. The AV-621

More information

Ceramics, Cracow, Poland

Ceramics, Cracow, Poland Chemically and physically functionalized carbon composites a prospective material for tissue treatment S.Blazewicz 1*, E.Stodolak 1, E. Staszkow 2, T.Mikolajczyk 3 1 AGH University of Science and Technology,

More information

Physical Dry Conditioned Unit Test method

Physical Dry Conditioned Unit Test method Technical Data Sheet Ixef 1022 is a 50% glass-fiber reinforced, general purpose compound that exhibits very high strength and rigidity, outstanding surface gloss, and excellent creep resistance. General

More information

Proven 1-4, Safe Performance. Product overview

Proven 1-4, Safe Performance. Product overview Proven 1-4, Safe Performance Product overview DePuy Polyethylene: proven 1-4, safe performance Polyethylene has been used as an orthopaedic bearing material for more than 4 years. Over this period of time

More information

HIGH PERFORMANCE MIX SPECIFICATIONS

HIGH PERFORMANCE MIX SPECIFICATIONS Strong-Seal Systems HIGH PERFORMANCE MIX SPECIFICATIONS INTENT: To provide a system for manhole reconstruction that stops inflow, infiltration, exfiltration, restores structural integrity and provides

More information

Model for Predictive Analysis of the Quantity of Water Evaporated during the Primary-Stage Processing of Bioceramic Material Sourced from Kaolin

Model for Predictive Analysis of the Quantity of Water Evaporated during the Primary-Stage Processing of Bioceramic Material Sourced from Kaolin Journal of Minerals & Materials Characterization & Engineering, Vol. 9, No.2, pp.147-155, 2010 jmmce.org Printed in the USA. All rights reserved Model for Predictive Analysis of the Quantity of Water Evaporated

More information

DuPont Rynite 545 NC010 (Preliminary Data)

DuPont Rynite 545 NC010 (Preliminary Data) PRODUCT INFORMATION DuPont Rynite 545 NC010 (Preliminary Data) Product Information Common features of Rynite thermoplastic polyester include mechanical and physical properties such as excellent balance

More information

Calcium Phosphate Based Biomaterials for Bone Augmentation

Calcium Phosphate Based Biomaterials for Bone Augmentation Digital Comprehensive Summaries of Uppsala Dissertations from the Faculty of Science and Technology 1700 Calcium Phosphate Based Biomaterials for Bone Augmentation JUN LUO ACTA UNIVERSITATIS UPSALIENSIS

More information

Pre-Congress Bone-tec 2013 Clinical Translational Workshop

Pre-Congress Bone-tec 2013 Clinical Translational Workshop Pre-Congress Bone-tec 2013 Clinical Translational Workshop Sat, Dec 14, 830-1600, Tan Tock Seng Hospital, Main Building, Level 3, Seminar Rm 1 & 2, 11 Jalan Tan Tock Seng, Singapore 308433 Clinical translational

More information

Lecture Outline. History. Purpose? Func:on of Bioscaffolds. Extracellular Matrix (ECM) 12/08/15

Lecture Outline. History. Purpose? Func:on of Bioscaffolds. Extracellular Matrix (ECM) 12/08/15 Associate Professor Rod Dilley Dr Rob Marano Ear Sciences Centre School of Surgery Harry Perkins Research Building 4 th Floor Lecture Outline History Purpose Functions Properties Approaches to bioscaffold

More information

CHAPTER 12: mechanical properties of ceramics

CHAPTER 12: mechanical properties of ceramics CHAPTER 12: mechanical properties of ceramics ISSUES TO ADDRESS... Mechanical Properties: What special provisions/tests are made for ceramic materials? Chapter 12-1 COORDINATION # AND IONIC RADII Coordination

More information

Characterization and Testing of Fiber Reinforced Concrete (American Standards)

Characterization and Testing of Fiber Reinforced Concrete (American Standards) Workshop on FIBER REINFORCED CONCRETE (FRC): MATERIALS, APPLICATIONS AND DESIGN ASPECTS UNIVERSITY OF SHARJAH, UNITED ARAB EMIRATES 22-23 APRIL 2018 Characterization and Testing of Fiber Reinforced Concrete

More information

IOP Conference Series: Materials Science and Engineering PAPER OPEN ACCESS

IOP Conference Series: Materials Science and Engineering PAPER OPEN ACCESS IOP Conference Series: Materials Science and Engineering PAPER OPEN ACCESS Study and characterization of bio-active glass coating composite with and without hydroxyapatite on titanium and SS316L to regenerate

More information