Citric acid anhydrous

Transcription

1 Safety Data Sheet Citric acid anhydrous 1. Product and Company Identification Product name Product code Company information Citric acid anhydrous Ro Enquiries: F. HoffmannLa Roche AG Postfach CH4070 Basel Switzerland Phone *4161/ Fax *4161/ Local representation: LV0000 LV1111 LV2222 LV3333 LV4444 LV5555 LV6666 LV Composition/Information on ingredients Chemical name Synonyms 2Hydroxy1,2,3propanetricarboxylic acid Citric acid Citric acid anhydrous fine granular 16/40 (WN ) Citric acid anhydrous fine granular 51N (WN ) Citric acid anhydrous granular 5N (WN ) Citric acid anhydrous powder (WN ) Citric acid anhydrous medium granular 1200 (WN ) Citric acid anhydrous fine granular 700 (WN ) CAS number EINECS number Roche number Ro /001 Empirical formula Molecular mass C6H g/mol H H H H 3. Hazards identification Most important hazards Irritating to eyes. Page: 1/5

2 4. Firstaid measures Eye contact Skin contact Inhalation to physician rinse immediately with tap water for 10 minutes open eyelids forcibly consult physician remove contaminated clothes, wash affected skin with water and soap do not use any solvents remove the casualty to fresh air and keep him/her calm consult physician treat symptomatically 5. Firefighting measures Suitable extinguishing media Specific hazards Protection of firefighters water spray jet, dry powder, foam, carbon dioxide consider dust explosion hazard precipitate gases/vapours/mists with water spray 6. Accidental release measures Methods for cleaning up collect solids (avoid dust formation) and hand over to waste removal rinse with plenty of water 7. Handling and storage Handling Technical measures Suitable materials Unsuitable materials transfer and handle only in enclosed systems local exhaust ventilation necessary take precautionary measures against electrostatic charging avoid dust formation; high dust explosion hazard stainless steel, enamel, glass, polyethylene, polypropylene aluminium, copper, zinc, steel Storage Storage conditions Validity Packaging materials in closed containers store in a dry place 36 months, 10 to 30 C, in the unopened original container, see "best use before" date stated on the label tightly closing; material: glass, stainless steel, polyethylene, polypropylene, PVC Page: 2/5

3 8. Exposure controls/personal protection Engineering Measures see 7. Monitoring Analytics sampling on glass fibre filter and gravimetric or chemical determination Personal protective equipment Respiratory protection Hand protection Eye protection in case of open handling or accidental release: particle mask or respirator with independent air supply protective gloves tightly fitting safety glasses 9. Physical and chemical properties Colour Form dour Density white powder, different granular size odourless, with a strong acidic taste g/cm 3 (20 C) Bulk density ~ 725 kg/m 3 Solubility Partition coefficient ~ mg/l, water soluble, ethanol badly soluble, diethyl ether insoluble, benzene insoluble, chloroform log Pow = 1.72 (octanol/water C) ph value (20 C) 2.2 (10 g/l aqueous solution) Melting temperature 152 to 154 C Ignition point (liquid) 500 C 10. Stability and reactivity Conditions to avoid Materials to avoid humidity temperatures above 40 C potassium tartrate, alkalis, alcaline earth carbonates and bicarbonates, metal nitrates, acetates, sulfides slightly hygroscopic Page: 3/5

4 11. Toxicological information Acute toxicity LD mg/kg (oral, mouse) LD50 > mg/kg (oral, rabbit) LD50 > mg/kg (oral, rat) Subacute toxicity NEL mg/kg/d (oral, rat, 5 d) Local effects Chronic toxicity eye: strongly irritant (rabbit) skin: moderately irritating (rabbit) well tolerated 2000 mg/kg/d (oral, rat; 90 days) Mutagenicity Carcinogenicity not mutagenic not carcinogenic (rat) not carcinogenic (mouse) Reproduction toxicity not teratogenic intermediate product of human metabolism (citric acid cycle) GRAS (generally recognized as safe for human consumption) 12. Ecological information Inherent biodegradability well inherently biodegradable 98 %, 7 days (ZahnWellens test, ECD No. 302 B) Ecotoxicity moderately toxic for planktonic crustaceans (Daphnia magna) LC0 80 mg/l barely toxic for fish (goldfish) LC0 625 mg/l barely toxic for microorganisms (Pseudomonas putida) EC0 (16 h) > mg/l barely toxic for protozoa (Entosiphon sulcatum) EC0 (72 h) 485 mg/l barely toxic for algae (Scenedesmus quadricauda) EC0 640 mg/l moderately toxic for algae (Microcystis aeruginosa) EC0 80 mg/l Air pollution observe local/national regulations 13. Disposal considerations Waste from residues incinerate in qualified installation with flue gas scrubbing observe local/national regulations regarding waste disposal 14. Transport information not classified by transport regulations Page: 4/5

5 15. Regulatory information EU classification and labelling Xi R36 Irritating to eyes. S24/25 Avoid contact with skin and eyes. Toxicity class (Switzerland) 5 Emission limit (Switzerland) Water hazard class (Germany) 50 mg/m 3 at massflux 0.5 kg/h (organic, particulate, class 1; own classification) 1: weakly hazardous for water (according to annex 1 or 2 of directive VwVwS of ) 16. ther information Use Safetylab number food and feed additive ingredient in pharmaceutical preparations, especially in effervescent tablets synergist in antioxidant mixtures BS2699 Edition documentation changes from previous version in sections 9 The information in this safety data sheet is based on current scientific knowledge. It should not be taken as expressing or implying any warranty concerning product characteristics. Page: 5/5