the biomarker testing laboratory

Transcription

1 the biomarker testing laboratory

2 RBM, the industry leader in comprehensive, multiplexed immunoassay testing services, delivers high-quality, reproducible biomarker results by industrializing the measurement process. One lab is not the same as the next. It s important to know if your samples are going to a lab that: Validates assays to clinical laboratory standards Validates assays in plasma and other biological fluids Uses calibrators and controls with every sample plate Monitors control samples over time to maintain reproducibility Uses the latest automation to minimize human error and ensure assay precision Provides assay sensitivity similar to ELISA Blocks interfering substances such as rheumatoid factor or heterophilic antibodies Provides hundreds of quantitative biomarker measurements using only microliters of sample Supports GLP studies and is CLIA certified Supports your project across the entire drug development continuum by providing linked products and services across species

3 The days of less is more in drug development are coming to an end. But capturing more data for the sake of more data is not a recipe for success. Drug developers have a vested interest in strategically analyzing more comprehensive and higher quality biomarker data sets to achieve crucial objectives: Maximize Safety Productivity & Minimizeim Inconsistency Cost Toxicity Risk Biopharma companies and outsourced central labs have invested millions of dollars in highpriced assay platforms and systems to address this need. Yet biomarker data remains plagued by poor reproducibility and reliability, resulting in erroneous conclusions. We believe there s a better way.

4 From early discovery through post-marketing surveillance, RBM delivers confidence through a host of industry-leading innovations: Multiplexing Expertise RBM s founders invented the original Luminex technology and are the industry experts on multiplexed applications. Our scientists have developed over 400 fully validated multiplexed immunoassays by far the most in the industry and have spent more than 10 years optimizing assay buffers and diluents to deliver consistent results in multiple complex matrices. Industrialized Service Using proprietary technology, automation and improved processes, RBM industrializes biomarker testing to meet the demands of today s studies. With standards typically found in clinical diagnostics, our technology and approach replace the uneven reproducibility and human error inherent in other testing methods. RBM delivers the most reliable results in the industry because we are optimized for one purpose: to accurately measure biomarkers from clinical samples. TruCulture - an industry first RBM pioneered TruCulture, the market s only standardized, reproducible whole blood culture system. Designed for simplicity and dramatic cost savings, TruCulture signals an end to the frustration and error in traditional ex vivo culture models such as PBMCs. Collect the sample, incubate and analyze. It s that simple. Complex Co-Culture Systems RBM has developed co-culture systems consisting exclusively of human immune cells and terminally differentiated, fully functional tissues. This allows for a detailed investigation of the absorption and bio-availability of test substances as well as their influence on the regulatory interactions during immune activation. Co-cultures exist for human skin, gut, lung, joint and vessel tissue. Customization One size does not necessarily fit all. If your study requires a specialized solution, contact your RBM representative for information about developing: Custom assay panels Custom assay kits Companion diagnostics Novel assay development

5 HumanMAP Version 1.6 RBM is the market leader for comprehensive, multiplexed immunoassays that are: Reproducible Quantitative Fully validated Reliable Cost efficient Don t get caught in the depths of meaningless biomarker background noise or sacrifice quality to gain quantity. Demand the same quality biomarker data in discovery and preclinical testing that regulators demand in the clinic. Let RBM s expertise and technology provide you with confidence in your biomarker data.

6 About RBM RBM, the market innovator for biomarker products and services, provides confidence in biomarker measurement across the entire drug development continuum. RBM is the first fully automated biomarker testing service focused on delivering high-quality, quantitative, multiplexed immunoassay data. In multiple species and sample types, our Multi Analyte Profile (MAP) testing panels measure proteins from a few to several hundred from just a single drop of blood. Our MAPs provide the most comprehensive, reliable and cost-effective solution for measuring protein expression patterns that are critical to drug safety and efficay, disease diagnosis and strategic drug development. For more information, visit us at RBM 3300 Duval Road Austin, Texas P Toll-free 866 RBM MAPS ( ) F info@rbmmaps.com