protect public health protect the most sensitive among us protect the environment prevent the spread of antibiotic resistant bacteria.

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1 TM PCS Process Cleaning Solutions is a Canadian company devoted to cleaning in such a way as to: protect public health protect the most sensitive among us protect the environment prevent the spread of antibiotic resistant bacteria.

2 1. Cleaning to Protect Public Health Successful removal of environmental surface contaminants in any commercial, institution or health care environment can be challenging. Aesthetic appearances can be misleading, as visibly clean surfaces are not a good indication of organic debris and microbial contamination. Cleaning with antimicrobial cleaners registered with Health Canada and relying on visual cleanliness alone provides a false sense of security, since organic debris and microbial contamination can still survive, depending on the process used and the type of surfaces cleaned. PCS offers a number of Health Canada DIN-registered Disinfectants. Disinfectant Cleaners for use on hard nonporous environmental surfaces in health care facilities, institutions, schools and the hospitality industries. PCS is committed to working with industry cleaning staff, institutional managers, public health officials and infection control to develop and provide the most effective Process Cleaning Solutions and methods, as validated by onsite ATP monitoring of cleaning efficacy. The PCS definition of cleaning to protect public health is as follows: Removal of organic surface contamination to very low levels not visually apparent, validated by scientific measurements with ATP monitoring or microbial testing. Disinfectant cleaner manufacturers and suppliers have in the past focused on disinfecting environmental surfaces with little regard to the science of cleaning. PCS is committed to the process of cleaning environmental surfaces properly, with or without disinfectants, to protect public health. There are in addition many opportunities to clean without the use of disinfectants. PCS offers a number of sustainable Process Cleaning Solutions without disinfectants, that can also be validated onsite through ATP monitoring. ATP is adenosine triphosphate and is present in all living cells. It is a key component in the energy transfer system within cells. The presence of high ATP levels is a good indicator of poor hygiene and low ATP levels is an excellent indicator of good hygiene. 2. Cleaning to Protect the Most Sensitive Among Us PCS is committed to protecting vulnerable populations, including chemically hypersensitive individuals, children, the elderly and hospital and chronic care patients, all of whom can be adversely affected by organic or chemical contamination of the indoor environment. PCS Process Cleaning Solutions contain no volatile ingredients, contain only natural ingredients and have no added scents. They are used with processes that effectively remove organic contamination from the building environment without depositing toxic chemical residues. (Such residues can be more hazardous than the organic contamination they are intended to remove.) All non-disinfectant PCS Process Cleaning Solutions are independently certified by the Envirodesic Certification Program. Envirodesic is an independent certification organization that certifies products for maximum indoor air quality, minimum environmental impact and sustainability, including the suitability for use around chemically hypersensitive individuals.

3 3. Cleaning to Protect the Environment Most consumers have a strong desire to go green in their procurement choices for cleaning chemicals. PCS is committed to producing cleaning products that do not add chemical contamination to either the indoor or the outdoor environment. All Process Cleaning Solutions are formulated with the following core principles: no synthetic chemicals no volatile ingredients no surfactants all ingredients are listed on the label. Synthetic detergent chemicals such as surfactants have prolonged impacts on aquatic and bacterial life, and can act synergistically with other chemical pollutants. 4. Cleaning to Prevent the Spread of Antibiotic Resistant Bacteria PCS cleaning processes are highly effective at maximizing the removal of organic microbial contamination from environmental surfaces, while minimizing prolonged residual toxic chemical exposures. We encourage the use of procedures that include an effective, verifiable cleaning step that physically removes bacteria and organic debris from environmental surfaces. For cases that require it, PCS markets disinfectants/disinfectant Cleaners that offer a lower dosage, greater stability, and greater safety than other current technologies. We work with client organizations to help determine how to minimize the use of disinfectants while still achieving and verifying the necessary level of hygiene. No synthetic chemicals No surfactants No volatile ingredients All ingredients are listed on the label Current practice for protecting public health involves the use of disinfectants or disinfectant cleaners. Disinfectants are chemicals registered with Health Canada that are capable of destroying both beneficial and harmful bacteria. They should not be considered environmentally sustainable because as currently used they can change the balance of nature and contribute to the further development of drug resistant bacterial populations. The European Commission Scientific Committee on Emerging and Newly Identified Health Risks states that current scientific evidence (including bacteriological, biochemical and genetic data) indicates that the use or misuse of certain active substances in biocidal products in various settings may contribute to the increased occurrence of antibiotic resistant bacteria, both in humans and in the environment. (See excerpt on the back cover) PCS cleaning processes are highly effective at maximizing the removal of organic microbial contamination from environmental surfaces, while minimizing prolonged residual toxic chemical exposures

4 Process CLEANING SOLutions Products Specific PCS Process Cleaning Solutions are available for health care, institutions, hospitality, learning centres and service providers for use with micro fiber and traditional cleaning cloths: PCS Sodium Hypochlorite Disinfectant/Disinfectant Cleaner DIN Concentrate contains 1.4% sodium hypochlorite active ingredient. Dilute 16 ml per litre of water. For use on hard non-porous environmental surfaces in health care facilities, institutions, schools and the hospitality industries x 2 L containers closed loop dispenser x 2 L containers x 3.78 L closed loop dispenser package PCS 7500 Oxidizing Disinfectant/Disinfectant Cleaners DIN Ready to use Disinfectant/Disinfectant cleaner for use on hard non-porous environmental surfaces in health care facilities, institutions, schools and the hospitality industries. Recommended for targeted use when needed. Contains 0.75 % / 7500 parts per million of sodium hypochlorite x 946 ml PCS 7000 Oxidizing Disinfectant/Disinfectant Cleaner DIN Concentrate dilute 32 mls per litre of water. For use on hard non porous environmental surfaces in health care facilities, institutions, schools and the hospitality industries. Contains 0.7 % / 7000 parts per million of sodium hypochlorite x 2 L PCS 1000 Oxidizing Disinfectant/Disinfectant Cleaner DIN Ready to use Disinfectant/Disinfectant cleaner. Contains 0.1 %/ 1000 parts per million of sodium hypochlorite x 946 ml x 2 L PCS 250 Oxidizing Disinfectant/Disinfectant Cleaner DIN Ready to use formulation. Contains 0.025% / 250 parts per million of sodium hypochlorite. Ideal product and concentration for most institutional needs x 946 ml x 2 L Chlorine test strips. 12 tubes of 100 strips 10 to 200 ppm available chlorine

5 PCS No Rinse Sanitizer For use exclusively in the food processing industry. Ready to use formulation. Ideal for use with PCS wet wiper system x 2 L Chlorine test strips included. PCS Oxidizing Wipes Disinfectant/Disinfectant Cleaner DIN Guarantee 0.25% Sodium Hypochlorite when packed x containers 35 pre moistened towels. Process General Purpose Cleaner Liquid concentrate Environmental cleaner that can be used for multiple cleaning tasks. Suitable for use around chemically hypersensitive individuals. There are many opportunities to clean with an environmental cleaner and accomplish excellent removal of organic soils including microbial contamination without the use of disinfectants. Use for : General Purpose Light duty 1 to 256 floors, windows, damp dusting Moderate cleaning task 1 to 64 Heavy Duty task 1 to 32 Carpet Cleaning Extraction in tank portables 1 to 128 In truck mount 1 to 256 Pre Spray 1 to 20 Low moisture 1 to x 2 L closed loop x 2 L open stock Process Non abrasive Cleaner A safe and effective cleaner for corrective cleaning and restoring the shine to tubs, taps and stainless steel sinks. Safe non acidic formulation can also be diluted for large area cleaning, suitable for use around chemically hypersensitive individuals x 946 ml Process Calcium Lime and Rust Remover PCS Process Cleaning Solutions Calcium Lime and Rust Remover gently removes soils without harming staff, surfaces cleaned or the environment, suitable for use around chemically hypersensitive individuals. Non Hazardous by WHMIS criteria x 946 ml Process Bowl and Bath Environmentally responsible natural cleaner suitable for use in and around chemically hypersensitive individuals. Non Hazardous by WHMIS criteria x 946 ml

6 Process Heavy duty cleaner An environmentally responsible cleaner suitable for use around chemically hypersensitive individuals. A liquid concentrated cleaner which is not corrosive and an outstanding general purpose cleaner x 2 L closed loop x 2 L open stock x 3.78 L closed loop Process Laundry CLEANER Plus Ideally suited for use by individuals who are sensitive to chemicals left in clothes, and for reduced environmental impacts. Highly effective in front loading washers and small commercial applications. Process Laundry Cleaner Plus is also an outstanding economical general purpose cleaner for many uses such as: Carpet cleaning, General purpose project cleaning., Floor cleaning, Windows kg bucket R D Portable dispenser Economical portable dispenser preset for a dilution of the concentrated PCS disinfectant cleaner. Black 1:50 Low Flow Burgundy 1:256 High Flow Wall mount dispensers A variety of customized dispensers customized for most professional needs. Micro fibre cloths. Blue packaged in bundles of 25 Red packaged in bundles of 25 Process Wet Wipe bulk pack rolls per case. Process High Friction Dry Wipes 6 rolls per case. Process Cleaning buckets with lids PCS cleaning buckets with dispensing lids

7 Hygiena System Sure Plus ATP Monitoring System Provides a very rapid validation of cleanliness levels of environmental surfaces cleaned. System Sure provides the confidence needed that your cleaning process is protecting public health. Use to establish cleaning processes, for staff training and to identify attached soils/ biofilms needing special deep cleaning. Sure trend data analysis software included. Ultrasnap ATP Swabs for use with System Sure Packages of 25 x 4 per carton Process CLEANING SOLutions Kits PCS has cleaning processes for hospitals, long term care, hospitality, professional service providers, day care and schools. Following a proven cleaning process provides confidence you are cleaning to protect public health. PCS provides all of the components and procedures to achieve consistent excellent results. Choose a PCS process that has been validated for efficacy. Process Cleaning Solutions Kits are provided with all the needed cleaning tools. Process Kit # 1 2 rolls of wet wipers. 2 PCS bucket 2 micro fiber cleaning cloths 2 rolls of high friction wipes enclosed in dispensing ctn. 2 x 2 L 250 Oxidizing Disinfectant/Disinfectant Cleaner 1 pkg of chlorine test strips The PCS process for cleaning with Kit # 1 maximizes removal of organic soils including microbial contamination to very low levels, minimizes chemical exposures, and reduces the potential of spreading contamination from the cleaning process. It also resolves the problem cleaning textured surfaces such as some commodes, over-bed tables, bed rails and other surfaces in health care facilities that are not smooth and that have proven to be difficult to clean. Components of Kit #1 can also be purchased separately in concentrates and bulk packaging Process Kit # 2 4 rolls of high friction wipes in dispenser cartons 4 containers (946 mls) of 250 Oxidizing Disinfectant/Disinfectant Cleaner. 1 pkg of chlorine test strips The PCS Process for cleaning Kit # 2 maximizes removal of organic soils including microbial contamination to very low levels, and provides increased cleaning efficacy to consumers of prepackaged wet disinfecting wipes. High efficiency cleaning is important if staff are relying on the disinfecting wipes for public health. Components of Kit #2 can also be purchased separately in concentrates and bulk packaging. 5922

8 Excerpt from the Scientific Committee on Emerging and Newly Identified Health Risks Assessment of the Antibiotic Resistance Effects of Biocides (The SCENIHR adopted this opinion after public consultation on 19 January 2009) Does current scientific evidence indicate that the use of certain active substances in biocidal products in various settings can contribute to the occurrence of antibiotic resistant bacteria, both in humans and in the environment? Yes, current scientific evidence (including bacteriological, biochemical and genetic data) does indicate that the use or misuse of certain active substances in biocidal products in various settings may contribute to the increased occurrence of antibiotic resistant bacteria, both in humans and in the environment. If yes, which types of areas of application create the highest risks for increasing antibiotic resistance? Any application that encompasses the widespread regular use of biocides at sub-lethal concentrations maintains a continuous selective pressure and thus increases the risk of selecting resistant bacteria. This may occur in a number of uses including hospitals, food production and cosmetics manufacturing etc. Antimicrobial molecules include antibiotics and biocides having a bactericidal/ bacteriostatic effect on bacteria. Active substances: The number of biocides in use is large. In the context of this mandate, biocides used for their surfactant properties, and for which the primary purpose is not their antimicrobial activity will not be considered. Some of the components that are commonly found in household products are surface active agents (surfactants). Surfactants have an intrinsic antibacterial activity (anionic, non-ionic, organic acids [active against Gram-positive bacteria] and compounds with alkyl chains [active against both Gram positive and negative bacteria]) (Birnie et al. 2000) Surface Active Agents ( Surfactants) Cationic agents (QACs) Anionic agents Nonionic agents Amphoteric (ampholytic) agents Antibiotic Resistance Effects of Biocides Type of antimicrobial (intrinsic potential for generating resistance) Based on our current state of knowledge and literature based evidence from mainly in vitro studies, bacteria have been shown to be able to withstand biocide exposure. The mechanisms by which bacteria can escape damage from biocides are complex and multiple, and are governed by a number of factors inherent to the biocide (e.g. concentration, contact time etc.) and to the bacteria (e.g. type, metabolic activity). However, some biocides, because of the nature of their interaction with the bacteria, would be more prone to induce resistance/tolerance. This group of high-risk biocides contains the quaternary ammonium compounds, biguanides (i.e. surface active agents) and phenolics. Metallic salts, such as silver could also be added to this list based on practice-based evidence from the 1960s-1970s. Highly reactive biocides such as oxidizing agents and alkylating agents would present a low risk when emerging bacterial resistance is concerned. This means that resistance is unlikely but not impossible. Examples of resistance to these biocides have been described, but they resulted mainly from an inappropriate usage of the biocide. Finally, for a number of biocides used heavily in consumer products and in the food industry (e.g. isothiazolones, anilides, diamidines, inorganic acids and their esters, alcohols), there is little information available on emerging resistance/tolerance when bacteria are exposed to their in-use concentrations. However, because of the nature of their interaction with the bacterial cell and their antimicrobial efficacy, these biocides would have to be classified for the time being as being of a medium risk in terms of emerging bacterial resistance until they can be properly assessed. Biocides are invaluable compounds that provide society with numerous benefits. They play an important role in the control of bacteria in a variety of applications. They are a precious resource that must be managed to avoid any loss in activity for as long as possible. Therefore, in order to preserve the role of biocides in infection control and hygiene, it is paramount to prevent the emergence of bacterial resistance and cross resistance through their appropriate and prudent use. Considering the high uncertainty in the in vivo evaluation of the effects of biocides on the emergence of antibiotic resistance, reporting of production and use of biocides should be promoted. Environmental monitoring programs for undesirable substances should include biocides Fisher Drive Peterborough, On, K9J 8N4 Toll Free: Tel: Fax: