Dr. Anwar Nasim Secretary General, Pakistan Academy of Sciences. Skype ID: anwarnasim1

Transcription

1 South Asia Biosafety Conference New Delhi Sep , 2013 Dr. Anwar Nasim Secretary General, Pakistan Academy of Sciences. Skype ID: anwarnasim1

2 Former Affiliations Chairman National Commission on Biotechnology ( 2001 Till date) Founding President of Federation of Asian Biotechnology Associations (FABA) Website:

3 Pakistan Independence Million Population The literacy rate ranges from 96% in Islamabad to 28% in the Kohlu District

4 Biotechnology in Pakistan PCSIR 1952 Food Technology Division, Lahore

5 Biotechnology in Pakistan RAGENI Early 1970s Radiation Genetics Institute (RAGENI) Established in Faisalabad A few years later this institute was extended and its name was changed to NIAB

6 A memory of 1981

7 The Muslim, March 7 th, 1981

8 INQUIRY MAY 1985

9 Establishment of National Core Group in Life Sciences (NCGLS) Recognizing the importance of Life Sciences the Higher Education Commission established the Core Group in Life Sciences with six different disciplines. These include Botany Genetics Microbiology Biochemistry/Molecular Biology Zoology Bioinformatics

10 Aims And Objective Promotion of teaching and research in Life Sciences in Pakistan. Identification of areas in Life Sciences which have a direct and major impact on the economy and well being of the country. Preparation of major projects in these areas. Human resource development in Life Sciences in Pakistan.

11 Achievements of NCGLS More than 3500 teachers have been trained in various advanced biological techniques through 55 national and International workshops and conferences. 4 Resource Centers have been established at various universities.

12 Institutes of Biotechnology and Genetic Engineering in Pakistan FAISALABAD JAMSHORO MAJOR BIOTECHNOLOGY CENTERS

13 Some Agri Biotechnology Products Crop Maize Soybean Cotton Canola Potato Tomato Papaya Banana Traits Insect resistance, herbicide tolerance Insect resistance, herbicide tolerance Insect resistance, herbicide tolerance Modified oil composition, herbicide tolerance Virus resistance, insect resistance, higher starch content Insect resistance, longer shelf life Virus resistance Virus resistance

14 Cartagena Protocol on Biosafety (CPB) Adopted 29 January 2000 and entered into force on 11 th September, 2003 Governing body is COP MOP and 143 parties Protocol Objective: Adequate protection in the safe transfer, handling and use of living modified organisms (LMOs) resulting from modern biotechnology that may have adverse effects on the environment & human health Scope: Transboundry movement, transit, handling and use of LMOs that can affect sustainable use of biological diversity... (Article 4) Pharmaceuticals are excluded Basic Premises of CPB Precautionary Principle Advance Informed Agreement (AIA) between the Parties Decision on the basis of scientific risk assesment

15 Pakistan Biosafety Rules, 2005 Notified on 21 st April, 2005; S.R.O. 336 (I)/2005 The Rules regulate: The manufacture, import, and storage of modified organisms and gene technological products for research, whether conducted in laboratories of teaching, research and development institute in public and private sector. The work involved laboratory work, field trial and commercial release of developed GMOs (plant, animals and micro organisms). The import, export, sale and purchase of GMOs for commercial purposes.

16 Pakistan Biosafety Rules, 2005 Notified on 21 st April, 2005; S.R.O. 336 (I)/2005 The Guidelines establishes the proper procedures to carry out following activities related to GMOs Research and development on GMOs and their products Release of GMOs and products for field trials Release of GMOs for commercial purpose.

17 Implementation Mechanism The mechanism of monitoring and implementation of the National Biosafety Guidelines, 2005 is built on the following three tiers as specified in the Biosafety Rules, 2005 National Biosafety Committee (NBC) Technical Advisory Committee (TAC) Institutional Biosafety Committee (IBC)

18 JURISDICTION OF VARIOUS BODIES Containment National Biosafety Guidelines Pakisatn Notification No. F.2(7)95 Bio

19 Process Flow Chart for Review of Applications for Permission to Undertake Laboratory, Field Trials and Commercial Release of GMOs & Their Products National Biosafety Guidelines Pakisatn Notification No. F.2(7)95 Bio

20 National Biosafety Centre Pakistan is the Party to Cartagena Protocol on Biosafety (CPB) under Convention on Biological Diversity (CBD) The establishment of implementation system s mandatory under CPB for the regulation of GMOs and their products The regulation of GMOs in the country is governed by Pakistan Biosafety Rules, 2005 notified under section 31 of Pakistan Environmental Protection Act (PEPA) 1997 National Biosafety Guidelines, 2005 provides the procedures to implement Biosafety Rules National Biosafety Centre project established in Pak EPA in April, 2006 The centre provides the implementation setup for the committees, National Biosafety Committee (NBC), Technical Advisory Committee (TAC) and Institutional Biosafety Committee (IBCs)

21 Objectives of the Centre Elucidate effects of GMOs on environment, health (plants, animals and human) Implement of Biosafety Rules and Guidelines to regulate GMOs related activities including import, export, production, handle, sell or release Hold NBC and TAC meetings, disseminate minutes and follow up implementation Review applications, furnish comments for technical evaluation and recommendations of TAC for NBC approvals Facilitate National Biosafety Committee in cooperation with relevant national/provincial authorities Facilitate exchange of technical expertise among research institutions and regulatory agencies Coordinate and develop linkages with foreign Biosafety committees, relevant agencies and International Biosafety Concerns Draft standards and procedures for Risk Assessment/Management and labeling of GMOs Coordinate supervision of GMOs related activities for Risk Assessment and Risk Management Mass Awareness of General Public and Capacity Building of the stakeholders

22 Working and Achievements of NBC Ratification of Cartagena Protocol on Biosafety 31 May, 2009 NBC served as the secretariat of the NBC and TAC Notified NBC and TAC, 38 IBCs NBC assisting TAC and IBCs for proper functioning Held 9 NBC and 16 TAC meetings, disseminated minutes and followed up implementation of decisions Reviewed 155 applications, furnish comments for technical evaluation and endow recommendations of TAC for NBC approvals Nine Training Workshops/Seminars were held for capacity building of the stakeholders Biosafety Brochure developed and widely distributed and Advertisements released in Newspapers, participated in Radio and TV programmes for mass awarness 35 Monitoring and evaluations visits of the institutes and Field Trial sites were conducted by TAC subcommittee for Monitoring GM Crops and NBC officers International training were received for the capacity building of the NBC officers International Liaisons were established with Foreign Biosafety committees, relevant agencies and international Biosafety concerns Facilitate NBC in cooperation with relevant national/provincial authorities oversseing GMOs

23 National Commission on Biotechnology Establishment: 30 th November 2001 Members: 15 Tasks and Future Initiatives: Human Resource Development. Strengthening research facilities in provinces. Funding young researchers for projects of high priority. Establishment of centre for Bioinformatics. To strengthen Government Private sector collaboration. Publications, T.V. and Radio Programmes. Encouraging research which increases export.

24 Future Vision Labeling standards of GM materials Acceptable standards (limit of GM materials) in foods Enhance the Mass Awareness of General Public and Stake Holders through all possible means of Print/Electronic Media and organizing Workshops/Seminars on Biosafety related issues and concerns Design and launch website of National Biosafety Centre and Link with Biosafety Clearing House managed by CPB/CBD Establishment of National Biosafety Centre Laboratory

25 Transgenic Grain Legumes (an example)

26 Di & Tri cistronic vector system m-rna RBS Atnhx1 GOI IRES Luciferase (Ali et al 2010) Transgenic 100mM NaCl WT 100mM NaCl

27 Development of transgenic Chickpea against abiotic stresses is in progress

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