Specifically designed for abdominal wall repair STRUCTURAL

Transcription

1 Specifically designed for abdominal wall repair STRUCTURAL

2 The Better Approach To a Better Allograft Better Standards: Board of Directors comprised primarily of surgeons 3-years run by surgeons, for surgeons Donor selection criteria set by Medical Board of Trustees Largest network of tissue recovery partners Seven million recipients. One hundred thousand donors. Exemplary safety record. Better Donors: Less than 3% of referred donors are accepted Low maximum age of acceptance Strict medical and social history restrictions Our standards on cancer exceed those set by the industry, FDA and most tissue banks Better Processing: No cross linking means better tissue incorporation No terminal sterilization No use of harsh processes that may affect the clinical performance of the tissue

3 FlexHD The biologic choice for complex abdominal wall reconstruction FlexHD is derived from human allograft skin that is minimally processed to remove epidermal and dermal cells. The process utilized preserves the extracellular matrix of the skin1 and serves as a framework to support cellular repopulation and vascularization at the surgical site.2,3 Unprocessed Human Skin FlexHD

4 STRENGTH YOU CAN TRUST Stronger than other biologics 4 Resists failure and stretching under tension better than other biologics 4 3 *P<.5 3 *P<.5 * * (MPa) 1 (MPa) Firm Surgimend 3. AlloDerm AlloMax Firm Surgimend 3. AlloDerm AlloMax Tensile strength Tensile modulus The ideal combination of strength and performance Stronger than AlloDerm RTM and RTM Supports cellular infiltration and revascularization Provides durable repair and fewer recurrences 6 Available in the sizes you need for abdominal wall repair

5 PERFORMANCE YOU CAN TRUST 4 Weeks Better in vivo performance FlexHD has natural components and architecture that support tissue ingrowth and neovascularization. 2,3,5 Permacol Ingrowth Neovascularization New Collagen Deposition 6 5 Grade Better cellular ingrowth FlexHD demonstrated better cellular ingrowth compared to Strattice and Permacol (over a 24-week study). 5 Weeks Permacol 6 (MPa) 4 2 Greater post-implantation strength FlexHD was 8 times stronger than Strattice 2 weeks after implantation. 2 2 weeks 1 Success % 5% More durable repair and better hernia repair outcome Preclinical studies showed 5% graft resorption and thinning in Strattice groups, resulting in a hernia defect or recurrence at 2 weeks weeks

6 CHOOSE THE SIZE, SHAPE AND THICKNESS YOU NEED. FlexHD FlexHD Diamond Tissue Code Dimensions Thickness Tissue Code Dimensions Thickness THICK THICK FlexHD 4cm X 7cm.8mm - 1.7mm FlexHD 6cm X 8cm.8mm - 1.7mm FlexHD 1cm X 16cm.8mm - 1.7mm FlexHD 12cm X 16cm.8mm - 1.7mm FlexHD 12cm X 24cm.8mm - 1.7mm 4D1331 FlexHD Diamond 21-23cm X cm.8mm - 1.7mm 4D1335 FlexHD Diamond 23-25cm X cm.8mm - 1.7mm ULTRA THICK 4D2331 FlexHD Diamond 21-23cm X cm 1.8mm - 4.mm 4D2335 FlexHD Diamond 23-27cm X cm 1.8mm - 4.mm FlexHD 16cm X 2cm.8mm - 1.7mm FlexHD 2cm X 2cm.8mm - 1.7mm FlexHD 2cm X 25cm.8mm - 1.7mm FlexHD 2cm X 3cm.8mm - 1.7mm ULTRA THICK FlexHD 4cm X 7cm 1.8mm - 4.mm FlexHD 8cm X 12cm 1.8mm - 4.mm FlexHD 1cm X 16cm 1.8mm - 4.mm FlexHD 12cm X 16cm 1.8mm - 4.mm FlexHD 12cm X 24cm 1.8mm - 4.mm FlexHD 16cm X 2cm 1.8mm - 4.mm FlexHD 2cm X 25cm 1.8mm - 4.mm FlexHD 2cm X 3cm 1.8mm - 4.mm References 1. Data on file. 2. Ngo M, Aberman H, Hawes ML, Choi B, Gertzman AA. (211) Evaluation of human acellular dermis versus porcine acellular dermis in an in vivo model for incisional hernia repair. Cell Tissue Bank, 12(2): Eberli D, Rodriguez S, Atala A, Yoo J. (21). In vivo evaluation of acellular human dermis for abdominal wall repair. J Biomed Mat Res A, 93(4): Data on file. 5. Zemlyak AY, Colavita PD, Tsirline VB, et al. Absorbable glycolic acid/trimethylene carbonate synthetic mesh demonstrates superior in-growth and collagen deposition. Abdominal Wall Reconstruction (AWR) Meeting; June 14-16, 212; Washington, DC. Abstract (AWR) abstracts212/35rev.pdf 6. Bochicchio GV, De Castro GP, Bochicchio KM, Weeks J, Rodriguez E, Scalea TM. (213) Comparison study of acellular dermal matrices in complicated hernia surgery. J Am Coll Surg, 217(4): MTF Customer Service: May Street Edison, NJ mtf.org AlloDerm is a registered trademark of LifeCell Allomax is a registered trademark of Davol Permacol is a trademark of Covidien Strattice is a trademark of Lifecell Surgimend is a registered trademark of TEI Biosciences Inc. FlexHD and FlexHD are registered trademarks of the Musculoskeletal Transplant Foundation, Edison, New Jersey Musculoskeletal Transplant Foundation MTF-FD-46