University of Groningen. Post-transcriptional control of C/EBPα and C/EBPβ proteins Zaini, Mohamad Amr

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1 University of Groningen Post-transcriptional control of C/EBPα and C/EBPβ proteins Zaini, Mohamad Amr IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2017 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Zaini, M. A. (2017). Post-transcriptional control of C/EBPα and C/EBPβ proteins: Insights into their role in energy homeostasis and diseases [Groningen]: University of Groningen Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:

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4 Mohamad Amr Zaini Amr was born on 20 th of June 1986 in Homs, Syria. He finished his Bachelor degree in pharmacy and pharmaceutical chemistry at the University of Damascus, Syria in 2008 and received his Master degree in molecular biology from the University of Skövde, Sweden in In this year he obtained a scholarship from the Swedish childhood cancer association (Barncancerfonden) to do a master project titled: Pancreas atrophy in mice following inactivation of the Coxsackie- and Adenovirus Receptor (CAR) gene in the group of Prof. Kerstin Sollerbrant Melefors at the pediatric endocrinology unit, Karolinska Institute (KI), Stockholm. Afterwards, Amr worked as a research associate in KI for one year. In 2012, Amr has been awarded the Leibniz Graduate School Academy (LGSA) PhD scholarship and started his PhD at Leibniz Institute for age related diseases, Fritz Lipmann Institute (FLI) in Jena, Germany under the supervision of Prof. Cornelis Calkhoven. He moved to Groningen in 2013 to complete his PhD studies in the same group when the group was relocated to the European Research Institute for the Biology of Ageing (ERIBA), University Medical Center Groningen (UMCG), The Netherlands. Now he is going to start a postdoc at the section of oncogenetics in CCA-VUmc Amsterdam in the research team of Dr. Rob Wolthuis and Dr. Josephine Dorsman. During his PhD period, Amr married to Hala Al Husaini and they have a daughter called Leen. 198

5 List of Publications: Zaini M.A., Müller C. and Calkhoven C.F. (2017) C/EBPα and C/EBPβ transcription factors: Their post-transcriptional control and roles in various tissues. (Manuscript in preparation). Zaini M.A., Müller C., de Yong T., Ackermann T., Hartleben G., Kortman G., Ghürs K.H., Fusetti F., Krämer OH., Guryev V. and Calkhoven C.F. (2017) A p300 and SIRT1 regulated acetylation switch of C/EBPα controls mitochondrial function. (Revised and resubmitted to Cell reports journal). Sin O., Jong T.D., Kudron M., Mata-Cabana A., Zaini M.A., Aprile F.A., Seinstra R., Stroo E., Prins R.W., Martineau C., Wang H., Hogewerf W., Steinhof A., Wanker E., Vendruscolo M., Calkhoven C.F., Reinke V., Guryev V., Nollen E.A.A. (2017) Identification of a Pol III-associated regulator of small non-coding RNAs that is linked with disease-associated protein aggregation. Molecular Cell. 65, Zaini M.A., Müller C., Ackermann T., Reinshagen J., Kortman G., Pless O. and Calkhoven C.F. (2017) A screening strategy for the discovery of drugs that reduce C/EBPβ-LIP translation with potential calorie restriction mimetic properties. Sci. Rep. 7, In K., Zaini M.A., Muller C., Warren A.J., Lindern M.V. and Calkhoven C.F. (2016) Shwachman Bodian Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mrnas. Nucleic Acids Res 44, Mirza M., Pang M.F., Zaini M.A., Haiko P., Tammela T., Alitalo K., Philipson L., Fuxe J. and Sollerbrant K. (2012) Essential role of the Coxsackie and Adenovirus Receptor (CAR) for development of the lymphatic system in mice. PLoS One 7(5):e