Centre for Digital Life Norway (DLN) - Interdisciplinary research, education and innovation

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1 Centre for Digital Life Norway (DLN) - Interdisciplinary research, education and innovation By Trygve Brautaset Centre leader

2 Biotechnology Biotechnology is a science in rapid development! Interdisciplinarity - combining life science + informatics + mathematics + engineering - increasingly needed! Bioeconomy - high expectations to innovation! Center for Digital Life Norway aims to meet these developments, expectations and needs; we are rigging ourselves for the future! 2

3 Myself; two roles two perspectives Centre leader Management & leadership Big lines Interdisciplinar Education & training Professor Scientist & project leader Focus Interdisciplinar Education & training 3

4 Outline Why establish this centre now? Interdisciplinar research benefits, challenges, how 4

5 Human genome project (2001) 5

6 DNA sequencencing faster; cheaper New Next Generation Sequencing machines produce billions of bases per experiment Today virtually everything being genome sequenced

7 Heavy infrastructure creates big data! OMICS technologies; genomics, proteomics, transcriptomics, metabolomics, fluxomics, phenomics, High-through-put technologies; screening, advanced chemical analysis, Imaging technologies, nanotechnologies, 7

8 From hypothesis driven to data driven Biotechnology 8

9 Synthetic Life - SYNTHIA (2010) «We are moving from reading to writing the genetic code..» (JC Venter) 9

10 Synthetic biology -standarized parts, bio bricks, DNA registries Motility Environmental sensors Protein & Chemical synthesis Logic communication Binding specificity 10

11 CRISPR/Cas9: Bacterial immunosystem with unique properties for genome editing 11

12 Biotechnology has a long tradition in modeling 12

13 Cell metabolic network - From a biochemists perspective 13

14 Cell metabolic network - From a mathematicians perspective 14

15 15

16 Science is interdisciplinary! Need for national coordination and collaboration between the sciences relevant for biotechnology (life science engineering mathematics informatics) Need for a national focus on excellence research, innovation and training Need to emphasize societal and ethical sides of biotechnology 16

17 Centre for Digital Life Norway (DLN) -Interdisciplinary research, education and innovation 17

18 DLN Research projects - interdisciplinarity! + More projects to come! Digital_Salomon 18

19 DLN Network - Goals and ambitions More interdisciplinary collaboration: share information, knowledge and expertize Train and educate next generation biotechnology scientists Integration of responsible research and innovation (RRI) into biotechnology research More innovation: coupling researchers, industry, and investors

20 Interdisciplinar research different sciences join to solve complex problems Benefits Complex problems need interdisciplinar approaches Interdisciplinary research groups obtain; Better funding possibilities Scientific excellence 20

21 Interdisciplinar research different sciences join to solve complex problems Challenges Training and education - a trend shift: How to develop interdisciplinarity skills and at the same time become a specialist? How to train next generation project leaders? 21

22 Interdisciplinar research different sciences join to solve complex problems How Collaborate in projects - creates commitments! Work together in the same room - develop mutual scientific understanding and «common language» DLN main target group; young scientists represent the future, more open minded to quick changes, digitalization and sharing 22

23 Annual conference on digital biotechnology Mathematicians, physicists, chemists, engineers, biotechnologists, systems biologists, plant physiologists, food scientists, material technologists, molecular biologists,

24 Centre for Digital Life Norway NTNU Department of Biotechnology, Faculty of Natural Sciences and Technology, Science building D1-177, Gløshaugen, Høgskoleringen 5 Address: Centre for Digital Life Norway, NTNU Department of Biotechnology, NO-7491 Trondheim Norway digitallifenorway.org