March 2015

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1 March 2015

2 REIG JOFRE: Who we are Reig Jofre(RJ) is a Spanish pharmaceutical company founded in Barcelona in The company is a family business with 26% of the shares listed in the Spanish Stock exchange and presently is one of the leading groups in the European pharmaceutical sector with strong industrial background. 2

3 RJ HISTORY Business Operations 1929 Founded by Ramón Reig Jofre 1993 Acquisition of Medea, specialized in dermatological products 1995 Acquisition of Orravan specialized in OTC products 1999 Acquisition of Sala, specialized in Hospital products 2009 Acquisition of BioglanAB, Sweden, specialized in dermatological and topical formulations 2014 Incorporation of RJ UK Ltd, to commercialized hospital products 2014 RJ Europe PTE, LTD. (Singapore) JV with local partner to commercialize pharmaceutical products in ASEAN countries Dic 2014 ReigJofremerges with Forté Pharma Laboratories, Monaco, reference in Europe in the field of food supplements sold in pharmacies RJ becomes the fifth Spanish pharmaceutical company listed on the stock exchange by turnover 3

4 RJ Locations RJ BARCELONA RJ TOLEDO RJ MADRID R+D and Regulatory Services Manufacturing plant for sterile (freeze-dried vials and ampoules), semi-solids liquids and solids Biotech Services RJ BIOGLAN (MALMÖ, SWEDEN) Beta-lactam manufacturing Plant. Two sites:: - Penicillins facility - Cephalosporanics sterile vials facility RJ UK LTD. Spain Sales &Marketing Division International Business Development RJ EUROPE PTE LTD. SINGAPORE ASEAN Countries - Sales and Marketing Division Specialized in semi-solid and liquid products for topical applications UK Sales and Marketing Division FORTÉ PHARMA MONACO Food Supplement Development, Sales and Marketing 4

5 Organizational Structure MANUFACTURING SITES RJ Toledo RJ Barcelona RJ Bioglan- Malmo Contracted Manufacturers PRODUCTS R&D + Regulatory Food Supplements (Forté Pharma) Antibiotics Betalactams Lyophilized and Injectable Generic Gynecology Dermatology Respiratory & Allergy MARKETS Sales and Mktng Spain France Nordic Markets Belgium/ Neth Portugal UK SouthEast Asia International Distributors International Licensees 5

6 Turnover(Million ) Number of Employees , , Turnover by manufacture Turnover by territory 34% 66% RJ own products Third party manufacture Sweden 6% UK 9% Others 21% Germany 10% France 17% Spain 37% 6

7 Some of our clients / Distributors / Licensees 7

8 Global Presence 8

9 RJ Products Product distribution by sales 15% 16% 69% Pharma Food supplement OTC DERMATOLOGY Complidermol 5α Zalve Impetine Amnioplus Prescription/ Specialist recommendation GYNECOLOGY Nife Par GynEC DX RESPIRATORY BloxAllergy Budesonide Pulmictan OTHERS DesmopressinOral Drops(Desmirin) Food Supplements FORTÉ PHARMA Laboratoires, HOSPITAL Monaco ANTIBIOTICS AmoxiClav -Weight Cephalosporines control / Slimming PenBenzatine --Energy Pipe-Taz --Beatuy Vancomycin -Health Daptomycin Voriconazole etc 9

10 RJ - Biotech Entrance for projects of biotechnological or biotech (innovative) products Development Services Service/Risk Co-development Investment Retain the manufacturing of products with added value Enter into the initial development stages for products with a high added value Work with partners who have complementary know-how Enter into synergic projects OPEN INNOVATION 10

11 R & D Strategies: Center of Excellence in Freeze-Drying process RJ invested during 2008 in a Center of Excellence in Lyophilization in RJ Barcelona site Equipment: pilot scale freeze-drier, freeze-dry microscopy, differential scanning calorimetry (DSC) and DTA-ER Scientific expertise (internal and external) which allow to study, formulate and develop products with an optimal lyophilisation cycle International presence in first line Conferences and publishing Articles Cycle development Avoiding the traditional trial and error approach and reducing time and costs From OFAT to QbD(DoE) Optimization of client s cycles and product performance 11

12 COMMITTED TO THE HEALTH AND INNOVATION