BCF CAREER EVENT, Bert de Jong Country Chair Netherlands SANL.SA

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1 BCF CAREER EVENT, Bert de Jong Country Chair Netherlands

2 Something about myself Education My career so far What makes me tick? What kind of boss do I try to be? 2

3 Why go for a career in the pharmaceutical industry? Close connection with patients International Entrepreneurial Dynamic Combining health care and business Work life balance What else? 3

4 Life is a health journey and Sanofi is there beside people as a health journey partner. We are focused on human health, operating worldwide and transforming scientific innovation into healthcare solutions across a broad spectrum of health conditions. 5 global business units Vaccines with Sanofi Pasteur Specialty care, rare diseases, multiple sclerosis, oncology and immunology with Sanofi Genzyme Diabetes and cardiovascular diseases General medicines and emerging markets Consumer healthcare reinforced in 2017 with the teams of Boehringer Ingelheim Sanofi at a glance Keys figures in ,000+ EMPLOYEES 145 NATIONALITIES 100 COUNTRIES 35.1 bn SALES By geographic areas United States Emerging Markets (1) Europe (2) Rest of the world (3) M M M M (1) World excluding U.S., Canada, Western & Eastern Europe (except Eurasia), Japan, South Korea, Australia, New Zealand and Puerto Rico. (2) Western Europe + Eastern Europe (except Eurasia: Russia, Ukraine, Georgia, Belarus, Armenia and Turkey). (3) Japan, South Korea, Canada, Australia, New Zealand, Puerto Rico. 6,964 M BUSINESS NET INCOME 4

5 SANOFI: A LONG TRADITION IN HEALTH BMP Sunstone, Medley, Merial, Nepentes, Zentiva, Kendricks, Oenobiol, Chattem, Acambis, Symbion, Shantha Biotechnics, Fovea, Bipar Sciences, Targegen, Genfar, Globalpharma, Genzyme Sanofi-Aventis 2004 Business Swap 2016 Aventis 1999 Sanofi Pasteur 2004 Sanofi-Synthélabo 1999 Marion 1950 Hoechst Marion Roussel 1997 Rorer 1910 Rhône-Poulenc Rorer 1990 Synthélabo 1970 Sanofi 1973 Roussel 1911 Connaught 1992 Institut Mérieux 1897 Delagrange 1931 Delalande 1924 Sterling 1901 Chinoin 1919 Clin Midy 1971 Hoechst 1863 Wittman & Poulenc 1860 Robert & Carrière 1901 Dausse 1834 Midy 1718

6 From vaccines to medicines. We help to face health care challenges Claude, Asthma Dean, Multiple Sclerosis Magali, Flu Gustavo, Pompe disease Abdelhadi, Diabetes De Filipijnen, Vaccinated against dengue Darcus en Vernee, High cholesterol Gérard, Cancer Mizutani, Pain 6

7 OUR ORGANIZATION 5 GLOBAL BUSINESS UNITS DIABETES AND CARDIOVASCULAR GENERAL MEDICINES AND EMERGING MARKETS SANOFI GENZYME SANOFI PASTEUR VACCINES CONSUMER HEALTHCARE GENERICS ESTABLISHED PRODUCTS RARE DISEASES MULTIPLE SCLEROSIS ONCOLOGY IMMUNOLOGY

8 HUMANS ON EARTH Billion 10 Billion GROWING LIFE EXPECTANCY years 66 years 76 years

9 Improving health care and the role of Sanofi By simplifying diagnostic and digital tools By better understanding of human genes: watch:ert video 6 minutes By better prevention By more pro active patients who increasingly self manage their illness 9

10 Our innovation model 4 R&D CENTRA Germany, France, Asia and North America 15% Of our turn over goes to R&D Growing from 5bn. to 6 bn. in 2020 Over Employees involved in R&D Cooperation with: Diabetes (3) Genetic diseases Oncology & Immunology (3) Met Verily, ex-google Life Science. 10

11 SIGNIFICANT FOOTPRINT IN THE BENELUX 5 sites Naarden, Gouda, Diegem, Brussel, Geel > 600 employees in Production site in Geel Diegem Brussel Geel 3 sites Sanofi European Treasury Centre and European Public Affairs team in Brussels

12 SANOFI IN THE NETHERLANDS: 2 SITES Naarden GBU SGZ & Functions European Headquarters SGZ Gouda GBUs & Functions

13 FOCUS ON We have transformed our research model to continuously offer patient-tailored solutions, while responding effectively to public health concerns. We have shortened our product development cycle with an average clinical cycle lasting roughly five years. More them 2/3 rd of molecules under development in our pipeline are biological. >16,000 PEOPLE INVOLVED IN R&D 6 bn yearly INVESTMENT IN R&D (BY 2020) 70 projects IN DEVELOPMENT PIPELINE 13

14 Something about the political debate on drug prices Let s work together Let s also look at the benefits for people and society Let s look at the facts (real costs, out of patent prices) Let s look for more RWE and alternative payment models 15

15 Life is a health journey, with ups and downs, which can be big or small, lifelong or temporary. We at Sanofi are there beside people in need as a health journey partner. Many are depending on us. We aim to protect, enable and support people facing health challenges so they can live life to its full potential. We are a diversified company focused on human health, operating worldwide and transforming scientific innovation into healthcare solutions. Sanofi, Empowering Life corporate presentation MARCH