CHEMICAL SEPARATION AND PURIFICATION: TECHNOLOGIES AND GLOBAL MARKETS. AVM116A October Shalini Shahani Dewan Project Analyst

Transcription

1 CHEMICAL SEPARATION AND PURIFICATION: TECHNOLOGIES AND GLOBAL MARKETS AVM116A October 2014 Shalini Shahani Dewan Project Analyst ISBN: BCC Research 49 Walnut Park, Building 2 Wellesley, MA USA (toll-free within the USA), or (+1) information@bccresearch.com

2 TABLE OF CONTENTS CHAPTER 1 INTRODUCTION 2 STUDY OBJECTIVES 2 REASONS FOR DOING THIS STUDY 2 CONTRIBUTIONS OF THE STUDY AND INTENDED AUDIENCE 2 SCOPE OF THE STUDY 2 METHODOLOGY 3 INFORMATION SOURCES 3 ANALYST'S CREDENTIALS 3 RELATED BCC RESEARCH REPORTS 4 BCC RESEARCH WEBSITE 4 DISCLAIMER 5 CHAPTER 2 SUMMARY 7 SUMMARY TABLE GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, SUMMARY FIGURE GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, 8 8 CHAPTER 3 OVERVIEW 10 SEPARATION 10 LIST OF SEPARATION TECHNIQUES AND EQUIPMENT 11 PURIFICATION 11 LIST OF PURIFICATION TECHNIQUES AND EQUIPMENT 12 SEPARATION AND PURIFICATION TECHNIQUES 12 CHROMATOGRAPHY 12 History of Chromatography 12 TABLE 1 HISTORY OF CHROMATOGRAPHY 12 Techniques of Chromatography 13 Liquid Chromatography 13 High Performance Liquid Chromatography (HPLC) 13 Applications 14 Affinity Chromatography 14 Applications 14 Gas Chromatography 14 GC Analysis 15 Applications 15 Ion Exchange Chromatography 15 Applications 16 Solid phase extraction (SPE) 16 Applications 16 MASS SPECTROMETRY 16 History of Mass Spectrometry 17 TABLE 2 HISTORY OF MASS SPECTROMETRY 17 Techniques of Mass Spectrometry 18 Gas Chromatography-Mass Spectrometry (GC-MS) 18 Applications 18

3 Liquid Chromatography (LC) or High Performance Liquid Chromatography (HPLC) Applications 19 Tandem Mass Spectrometry 19 Applications 19 Time-of-Flight Mass Spectrometry (TOF-MS) 19 Applications 19 Matrix-Assisted Laser Desorption/Ionization (MALDI) 20 Applications 20 Ion Mobility Spectrometry-Mass Spectrometry (IMS-MS) 20 Applications 21 Quadrupole Mass Spectrometry 21 Applications 21 Others 21 Fourier Transform Ion Cyclotron Resonance-Mass Spectrometry (FTICR-MS) Applications 22 Electrospray Ionization-Mass spectrometry (ESI-MS) 22 Advantages 22 Disadvantages 22 Applications 23 Thermal Ionization-mass Spectrometry (TIMS) 23 Applications 23 OTHERS 23 History of Other Techniques 23 TABLE 3 HISTORY OF OTHER TECHNIQUES 24 Electrolysis 24 Electrolysis Applications 25 Centrifugation 25 Applications 26 Sublimation 26 Applications 26 Distillation 27 Applications 27 Electrophoresis 27 Applications 27 Magnetic Separation 28 Applications CHAPTER 4 NEW DEVELOPMENTS AND REGULATORY ASPECTS 30 NEW PARTNERSHIPS, MERGERS AND ACQUISITIONS 30 TABLE 4 NEW PARTNERSHIPS, MERGERS AND ACQUISITIONS, APRIL 2014* 31 NEW PRODUCTS 31 TABLE 5 NEW INNOVATIONS IN SEPARATION AND PURIFICATION EQUIPMENT, APRIL 2014* REGULATORY ASPECTS 33 RECALLS 34 31

4 TABLE 6 RECALLS ON SEPARATION AND PURIFICATION EQUIPMENT, APRIL 2014* 34 CHAPTER 5 MARKET ANALYSIS 37 MARKET BY TYPE 37 TABLE 7 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, FIGURE 1 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, CHROMATOGRAPHY EQUIPMENT 39 Market Overview 39 Market Revenue 40 TABLE 8 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY TYPE, FIGURE 2 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT, BY TYPE, MASS SPECTROMETRY EQUIPMENT 42 Market Overview 42 Market Revenue 44 TABLE 9 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT, BY TYPE, FIGURE 3 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT, BY TYPE, OTHER SEPARATION AND PURIFICATION EQUIPMENT 45 Market Overview 45 Market Revenue 46 TABLE 10 GLOBAL MARKET FOR OTHER EQUIPMENT BY TYPE, THROUGH 2019 ($ FIGURE 4 GLOBAL MARKET FOR OTHER EQUIPMENT BY TYPE, THROUGH 2019 ($ MARKET SHARE 47 TABLE 11 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, 2013 (%) FIGURE 5 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, 2013 (%) MARKET BY REGION 48 MARKET OVERVIEW 48 MARKET REVENUE 49 TABLE 12 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY REGION, FIGURE 6 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY REGION, CHROMATOGRAPHY EQUIPMENT 50 Market Overview 50 Market Revenue 51 TABLE 13 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 7 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY REGION, Liquid Chromatography Equipment

5 TABLE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 8 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY EQUIPMENT BY REGION, Gas Chromatography Equipment 54 TABLE 15 GLOBAL MARKET FOR GAS CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 9 GLOBAL REVENUE OF GAS CHROMATOGRAPHY EQUIPMENT, BY REGION, ($ Ion Chromatography Equipment 55 TABLE 16 GLOBAL MARKET FOR ION CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 10 GLOBAL MARKET FOR ION CHROMATOGRAPHY EQUIPMENT BY REGION, Other Chromatography Equipment 56 TABLE 17 GLOBAL MARKET FOR OTHER CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 11 GLOBAL MARKET FOR OTHER CHROMATOGRAPHY EQUIPMENT BY REGION, MASS SPECTROMETRY EQUIPMENT 57 Market Overview 57 Market Revenue 59 TABLE 18 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY REGION, FIGURE 12 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY REGION, GC-MS Equipment 60 TABLE 19 GLOBAL MARKET FOR GAS CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, FIGURE 13 GLOBAL MARKET FOR GAS CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, ($ LC-MS Equipment 61 TABLE 20 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, FIGURE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, ($ Other MS Equipment 62 TABLE 21 GLOBAL MARKET FOR OTHER MASS SPECTROMETRY EQUIPMENT BY REGION, FIGURE 15 GLOBAL MARKET FOR OTHER MASS SPECTROMETRY EQUIPMENT BY REGION, ($ OTHER SEPARATION AND PURIFICATION EQUIPMENT 63 Market Overview 64 Market Revenue 64 TABLE 22 GLOBAL MARKET FOR OTHER EQUIPMENT BY REGION, THROUGH 2019 ($ FIGURE 16 GLOBAL MARKET FOR OTHER EQUIPMENT BY REGION, ($ Electrophoresis Equipment 65 TABLE 23 GLOBAL MARKET FOR ELECTROPHORESIS EQUIPMENT BY REGION,

6 FIGURE 17 GLOBAL MARKET FOR ELECTROPHORESIS EQUIPMENT, BY REGION, ($ Other Equipment (Magnetic Separation, Centrifugation, Sublimation, Distillation, etc.) TABLE 24 GLOBAL MARKET FOR OTHERS (MAGNETIC SEPARATION, CENTRIFUGATION, SUBLIMATION, DISTILLATION, ETC.) EQUIPMENT BY REGION, FIGURE 18 GLOBAL MARKET FOR OTHERS (MAGNETIC SEPARATION, CENTRIFUGATION, SUBLIMATION, DISTILLATION, ETC.) EQUIPMENT BY REGION, ($ MARKET SHARE 67 TABLE 25 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY REGION, 2013 (%) FIGURE 19 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY REGION, 2013 (%) CHAPTER 6 MARKET BY END USERS 70 BIOPHARMACEUTICALS 70 FOOD 70 ENVIRONMENT 71 OTHERS 71 MARKET OVERVIEW 72 MARKET REVENUE 72 TABLE 26 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, FIGURE 20 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, ($ MARKET SHARE 73 TABLE 27 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, 2013 (%) FIGURE 21 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, 2013 (%) CHROMATOGRAPHY EQUIPMENT 74 MARKET OVERVIEW 75 MARKET REVENUE 76 TABLE 28 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY END USERS, FIGURE 22 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY END USERS, ($ MASS SPECTROMETRY EQUIPMENT 77 MARKET OVERVIEW 78 MARKET REVENUE 81 TABLE 29 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY END USERS, FIGURE 23 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY END USERS, ($ OTHER SEPARATION AND PURIFICATION EQUIPMENT 82 MARKET OVERVIEW 83 MARKET REVENUE 83 TABLE 30 GLOBAL MARKET FOR OTHER EQUIPMENT BY END USERS, THROUGH 2019 ($

7 FIGURE 24 GLOBAL MARKET FOR OTHER EQUIPMENT BY END USERS, ($ 84 CHAPTER 7 INDUSTRY STRUCTURE 86 MASS SPECTROMETRY EQUIPMENT 86 MARKET LEADERS 86 TABLE 31 LEADING MANUFACTURERS/SUPPLIERS OF MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 MARKET SHARE 89 TABLE 32 MARKET SHARE OF THE MANUFACTURERS/ SUPPLIERS FOR MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 25 MARKET SHARE OF THE MANUFACTURERS/SUPPLIERS FOR MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) CHROMATOGRAPHY EQUIPMENT 90 MARKET LEADERS 90 TABLE 33 LEADING MANUFACTURERS/ SUPPLIERS OF CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 MARKET SHARE 93 TABLE 34 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 26 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) OTHER SEPARATION AND PURIFICATION EQUIPMENT 94 MARKET LEADERS 94 TABLE 35 LEADING MANUFACTURERS/SUPPLIERS OF OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 MARKET SHARE 95 TABLE 36 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 27 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) CHAPTER 8 PATENT ANALYSIS 98 PATENTS BY YEAR 98 TABLE 37 PATENTS BY YEAR, 2010-APRIL 2014 (NUMBER) 98 FIGURE 28 PATENTS BY YEAR, 2010-APRIL 2014 (%) 98 PATENTS BY CATEGORY 99 TABLE 38 PATENTS BY CATEGORY, 2010-APRIL 2014 (NUMBER) 99 FIGURE 29 PATENTS BY CATEGORY, 2010-APRIL 2014 (NUMBER) 99 PATENTS BY TYPE 100 TABLE 39 PATENTS BY TYPE, APRIL 2014 (NUMBER) 100 FIGURE 30 PATENTS BY TYPE, 2010-APRIL 2014 (NUMBER) 101 PATENTS BY COMPANY 102 TABLE 40 PATENTS BY COMPANY, 2010-APRIL 2014 (NUMBER) 102 PATENTS BY COUNTRY 104 TABLE 41 PATENTS BY COUNTRY, 2010-APRIL 2014 (NUMBER) 105 PATENTS BY ASSIGNEE 105 TABLE 42 PATENTS BY ASSIGNEE, 2010-APRIL 2014 (NUMBER) 106

8 CHAPTER 9 CURRENT SITUATION 108 CHAPTER 10 COMPANY PROFILES 111 AB SCIEX 111 ACUTRONIC USA INC. 111 AGILENT TECHNOLOGIES INC. 111 ALFA WASSERMANN INC. 112 APOGEE DESIGNS LTD. 112 BASELINE INC. 113 BAYGENE BIOTECH COMPANY LTD. 113 BECKMAN COULTER INC. 113 BERGMANN MESSGERAETE ENTWICKLUNG KG 114 BIO-RAD LABORATORIES INC. 114 BRUKER CORP. 115 BUCK SCIENTIFIC 115 C. GERHARDT 116 DANI INSTRUMENTS S.P.A. 116 DIONEX CORP. 116 EXCELLIMS CORP. 117 FOTODYNE INC. 117 GE HEALTHCARE LIFE SCIENCES 118 GILSON INC. 118 HAMILTON COMPANY 119 HELENA LABORATORIES 119 HICHROM LTD. 119 HITACHI HIGH TECHNOLOGIES 120 HOEFER INC. 120 INFICON 121 JEOL USA INC. 121 KORE TECHNOLOGY LTD. 121 LUKNOVA INC. 122 NACALAI TESQUE 122 NUAIRE 123 PERKINELMER 123 QUARK GLASS 123 REGIS TECHNOLOGIES 124 SEBIA 124 SHIMADZU CORP. 124 SIGMA-ALDRICH 125 SPECTRUM CHROMATOGRAPHY 125 THERMO FISHER SCIENTIFIC INC. 126 TOSOH BIOSCIENCE 126 VWR INTERNATIONAL 127 WATERS CORP. 127 W R GRACE 128

9 CHAPTER 11 APPENDIX I-ABBREVIATIONS 130

10 LIST OF TABLES TABLE HEADING SUMMARY TABLE GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, TABLE 1 HISTORY OF CHROMATOGRAPHY 12 TABLE 2 HISTORY OF MASS SPECTROMETRY 17 TABLE 3 HISTORY OF OTHER TECHNIQUES 24 TABLE 4 NEW PARTNERSHIPS, MERGERS AND ACQUISITIONS, APRIL 2014* 31 TABLE 5 NEW INNOVATIONS IN SEPARATION AND PURIFICATION EQUIPMENT, APRIL 2014* TABLE 6 RECALLS ON SEPARATION AND PURIFICATION EQUIPMENT, APRIL 2014* TABLE 7 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, TABLE 8 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY TYPE, THROUGH 2019 ($ TABLE 9 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT, BY TYPE, TABLE 10 GLOBAL MARKET FOR OTHER EQUIPMENT BY TYPE, THROUGH 2019 ($ TABLE 11 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, 2013 (%) TABLE 12 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY REGION, TABLE 13 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY REGION, TABLE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY EQUIPMENT BY REGION, TABLE 15 GLOBAL MARKET FOR GAS CHROMATOGRAPHY EQUIPMENT BY REGION, TABLE 16 GLOBAL MARKET FOR ION CHROMATOGRAPHY EQUIPMENT BY REGION, TABLE 17 GLOBAL MARKET FOR OTHER CHROMATOGRAPHY EQUIPMENT BY REGION, TABLE 18 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY REGION, TABLE 19 GLOBAL MARKET FOR GAS CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, TABLE 20 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, TABLE 21 GLOBAL MARKET FOR OTHER MASS SPECTROMETRY EQUIPMENT BY REGION, TABLE 22 GLOBAL MARKET FOR OTHER EQUIPMENT BY REGION, THROUGH 2019 ($ TABLE 23 GLOBAL MARKET FOR ELECTROPHORESIS EQUIPMENT BY REGION, TABLE 24 GLOBAL MARKET FOR OTHERS (MAGNETIC SEPARATION, CENTRIFUGATION, SUBLIMATION, DISTILLATION, ETC.) EQUIPMENT BY REGION, TABLE 25 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY REGION, 2013 (%) TABLE 26 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY END USERS,

11 TABLE HEADING TABLE 27 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, 2013 (%) TABLE 28 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY END USERS, TABLE 29 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY END USERS, TABLE 30 GLOBAL MARKET FOR OTHER EQUIPMENT BY END USERS, THROUGH 2019 ($ TABLE 31 LEADING MANUFACTURERS/SUPPLIERS OF MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 TABLE 32 MARKET SHARE OF THE MANUFACTURERS/ SUPPLIERS FOR MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) TABLE 33 LEADING MANUFACTURERS/ SUPPLIERS OF CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 TABLE 34 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) TABLE 35 LEADING MANUFACTURERS/SUPPLIERS OF OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 TABLE 36 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) TABLE 37 PATENTS BY YEAR, 2010-APRIL 2014 (NUMBER) 98 TABLE 38 PATENTS BY CATEGORY, 2010-APRIL 2014 (NUMBER) 99 TABLE 39 PATENTS BY TYPE, APRIL 2014 (NUMBER) 100 TABLE 40 PATENTS BY COMPANY, 2010-APRIL 2014 (NUMBER) 102 TABLE 41 PATENTS BY COUNTRY, 2010-APRIL 2014 (NUMBER) 105 TABLE 42 PATENTS BY ASSIGNEE, 2010-APRIL 2014 (NUMBER)

12 LIST OF FIGURES FIGURE TITLE SUMMARY FIGURE GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, FIGURE 1 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, FIGURE 2 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT, BY TYPE, FIGURE 3 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT, BY TYPE, FIGURE 4 GLOBAL MARKET FOR OTHER EQUIPMENT BY TYPE, THROUGH 2019 ($ FIGURE 5 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY CATEGORY, 2013 (%) FIGURE 6 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY REGION, FIGURE 7 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 8 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 9 GLOBAL REVENUE OF GAS CHROMATOGRAPHY EQUIPMENT, BY REGION, ($ FIGURE 10 GLOBAL MARKET FOR ION CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 11 GLOBAL MARKET FOR OTHER CHROMATOGRAPHY EQUIPMENT BY REGION, FIGURE 12 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY REGION, FIGURE 13 GLOBAL MARKET FOR GAS CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, ($ FIGURE 14 GLOBAL MARKET FOR LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY EQUIPMENT BY REGION, ($ FIGURE 15 GLOBAL MARKET FOR OTHER MASS SPECTROMETRY EQUIPMENT BY REGION, ($ FIGURE 16 GLOBAL MARKET FOR OTHER EQUIPMENT BY REGION, ($ FIGURE 17 GLOBAL MARKET FOR ELECTROPHORESIS EQUIPMENT, BY REGION, ($ FIGURE 18 GLOBAL MARKET FOR OTHERS (MAGNETIC SEPARATION, CENTRIFUGATION, SUBLIMATION, DISTILLATION, ETC.) EQUIPMENT BY REGION, ($ FIGURE 19 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY REGION, 2013 (%) FIGURE 20 GLOBAL MARKET FOR SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, ($ FIGURE 21 MARKET SHARE OF SEPARATION AND PURIFICATION EQUIPMENT BY END USERS, 2013 (%) FIGURE 22 GLOBAL MARKET FOR CHROMATOGRAPHY EQUIPMENT BY END USERS, ($ FIGURE 23 GLOBAL MARKET FOR MASS SPECTROMETRY EQUIPMENT BY END USERS, ($ FIGURE 24 GLOBAL MARKET FOR OTHER EQUIPMENT BY END USERS, ($

13 FIGURE TITLE FIGURE 25 MARKET SHARE OF THE MANUFACTURERS/SUPPLIERS FOR MASS SPECTROMETRY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 26 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR CHROMATOGRAPHY EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 27 MARKET SHARE OF MANUFACTURERS/SUPPLIERS FOR OTHER EQUIPMENT USED IN SEPARATION AND PURIFICATION, 2013 (%) FIGURE 28 PATENTS BY YEAR, 2010-APRIL 2014 (%) 98 FIGURE 29 PATENTS BY CATEGORY, 2010-APRIL 2014 (NUMBER) 99 FIGURE 30 PATENTS BY TYPE, 2010-APRIL 2014 (NUMBER)