Research Xchange Forum Insights Translation Solutions. Agenda February 2017 Sartorius College Goettingen, Germany

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1 Research Xchange Forum Insights Translation Solutions Agenda February 2017 Sartorius College Goettingen, Germany

2 Welcome What to expect Learn about the latest Insights from the fields of oncology and exchange ideas as to their Translation into viable Solutions. Our Research Xchange Forum provides keynote lectures from internationally renowned academics and leading biopharma R&D executives, addressing the latest developments in cancer research and treatments. To stimulate dialogue about the next generation of innovative solutions interdisciplinary research we are bringing together academia, industry and cross-sector organizations culminating in a panel discussion between stakeholders. During a joint dinner you can deepen your discussions and explore networking opportunities in an exciting and challenging environment. Complete your forum experience with optional demo & discussion sessions to help you boost your research results when it comes to virus quantification and cell screening. Moreover, get a chance for an exclusive inside view into the working processes of Sartorius during a plant tour. Intro Agenda

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4 Wednesday, February 22 Chair: Dr. Sven Wagner, Vice President New Business Development Sartorius 08:10 Transfer to Sartorius College (from hotel) 08:30 09:45 Registration 08:45 09:45 Optional Plant Tour Please register (max. 40 participants) 09:45 10:00 Welcome & Introduction Michael Melingo, Sartorius, Germany Executive Vice President LPS Marketing Sales Services 10:00 10:30 Keynote Presentation Juno s Cell Handling Platform for Efficient Production of Gene-Modified T-Cells 10:30 11:00 Coffee Break Exhibition 11:00 11:30 Lecture Potential of Cubosomes and related systems for drug and nutrient delivery 11:30 12:00 Lecture Using the ique Screener PLUS for primary screening within Protein and Cellular sciences at Immunocore 12:00 14:00 Lunch Exhibition Demo & Discussion Sessions Dr. Lothar Germeroth, JUNO Therapeutics, Germany Senior Vice President, Managing Director Dr. Laurent Sagalowicz, Nestlé, Switzerland Expert Delivery Systems Encapsulation Stephen Hearty, Immunocore, UK Principal Scientist Intro Agenda

5 13:00 13:45 Optional Demo & Discussion Session Rapid screening and parallel processing of cell line development experiments (with IntelliCyt screening platform and mini bioreactor system ambr 15) Please register (max. 20 participants) 13:00 13:45 Optional Demo & Discussion Session Rapid real-time viral quantification (with the ViroCyt Counter) Please register (max. 20 participants) 14:00 14:30 Keynote Presentation Towards targeting phosphatases in cancer 14:30 15:00 Lecture Genomic Perturbations Reveal Distinct Regulatory Networks in Intrahepatic Cholangiocarcinoma 15:00 15:30 Lecture The p53-mdm2 system modifies chromatin and DNA replication 15:30 16:00 Coffee Break Exhibition 16:00 17:00 Panel Discussion The interplay of academia, industry and society How can we improve knowledge transfer? 17:00 17:10 Sum up & Closing 17:15 Transfer to hotel (from Sartorius College) 18:45 Transfer to networking dinner (from Hotel) Prof. Dr. Maja Banks-Köhn, Germany European Molecular Biology Laboratory (EMBL), soon professorship University Freiburg Assoc. Prof. Dr. Jesper Bøje Andersen, Denmark Biotech Research & Innovation Center (BRIC), University of Copenhagen Prof. Dr. med. Matthias Dobbelstein, Germany Institute of Molecular Oncology, Ernst Caspari Haus Göttingen, Center of Molecular Biosciences, GZMB

6 Thursday, February 23 Chair: Dr. Erika Trauzzi, Director of Regenerative Medicine, Sartorius 08:20 Transfer to Sartorius College (from hotel) 08:50 09:00 Opening of Day 2 Chair: Dr. Erika Trauzzi Director Regenerative Medicine 09:00 09:30 Keynote Presentation Antibody Drug Conjugates State of the Art, Trends, Challenges and Opportunities 09:30 10:00 Lecture Immune Oncotherapy: The innate pathway challenge 10:00 10:30 Lecture Evaluation of a novel bench-top stirred-tank bioreactor for process development of autologous T-cell therapies 10:30 11:00 Coffee Break Exhibition 11:00 11:30 Keynote Presentation Non-coding RNAs in solid cancer: from bedside to bench and back 11:30 12:00 Lecture Extracellular matrix proteins of stem cell niches: role in breast cancer metastasis Zaki Sellam, Avicenna Oncology, Switzerland Founder and CEO Dr. Jamel Chargui, Innate Pharma, France Procurement Manager Dr. Henrieta Fraser, The Cell and Gene Therapy Catapult, UK Senior Process Development Scientist Assoc. Prof. Dr. Ondřej Slabý, Czech Republic Central European Institute of Technology (CEITEC) Dr. Thordur Oskarsson, Germany Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM ggmbh), German Cancer Research Center (DKFZ) Intro Agenda

7 12:00 12:30 Lecture Ultra scale-down approach to the early prediction of the impact of industrial scale continuous centrifugation and depth-filtration on the recovery and purification of new therapeutic candidates 12:30 12:45 Sum up & Closing 12:45 14:45 Lunch Exhibition Plant Tour Demo & Discussion Sessions 13:15 14:00 Optional Plant Tour Please register (max. 40 participants) 13:15 14:00 Optional Demo & Discussion Session Rapid screening and parallel processing of cell line development experiments (with IntelliCyt screening platform and mini bioreactor system ambr 15) Please register (max. 20 participants) 13:15 14:00 Optional Demo & Discussion Session Rapid real-time viral quantification (with the ViroCyt Counter) Please register (max. 20 participants) Dr. Alex Chatel, University College London, UK Translational research manager

8 Venue: Conference address Sartorius College Otto Brenner Strasse Goettingen, Germany Your Contact: Romi Jeromis Sartorius Lab Instruments GmbH & Co. KG Phone: If you should have any questions, do not hesitate to contact us any time. We will be pleased to help you. Please note that photos and videos will be taken during the event. If you do not wish to be photographed, please let us know upon registration.