Microarrays in Diagnostics and Biomarker Development
|
|
- Ophelia Wilson
- 6 years ago
- Views:
Transcription
1 Microarrays in Diagnostics and Biomarker Development
2 .
3 Editor Microarrays in Diagnostics and Biomarker Development Current and Future Applications
4 Editor CoReBio PACA Luminy Science Park Marseille Cedex 9 France ISBN ISBN (ebook) DOI / Springer Heidelberg New York Dordrecht London Library of Congress Control Number: # Springer-Verlag Berlin Heidelberg 2012 This work is subject to copyright. All rights are reserved by the Publisher, whether the whole or part of the material is concerned, specifically the rights of translation, reprinting, reuse of illustrations, recitation, broadcasting, reproduction on microfilms or in any other physical way, and transmission or information storage and retrieval, electronic adaptation, computer software, or by similar or dissimilar methodology now known or hereafter developed. Exempted from this legal reservation are brief excerpts in connection with reviews or scholarly analysis or material supplied specifically for the purpose of being entered and executed on a computer system, for exclusive use by the purchaser of the work. Duplication of this publication or parts thereof is permitted only under the provisions of the Copyright Law of the Publisher s location, in its current version, and permission for use must always be obtained from Springer. Permissions for use may be obtained through RightsLink at the Copyright Clearance Center. Violations are liable to prosecution under the respective Copyright Law. The use of general descriptive names, registered names, trademarks, service marks, etc. in this publication does not imply, even in the absence of a specific statement, that such names are exempt from the relevant protective laws and regulations and therefore free for general use. While the advice and information in this book are believed to be true and accurate at the date of publication, neither the authors nor the editors nor the publisher can accept any legal responsibility for any errors or omissions that may be made. The publisher makes no warranty, express or implied, with respect to the material contained herein. Printed on acid-free paper Springer is part of Springer Science+Business Media (
5 Preface This is the second time I assemble a book on microarrays for Springer almost exactly 10 years after the first one (DNA microarrays: Gene expression applications. Springer Berlin Heidelberg 2001). During this interval, we have seen tremendous changes in the landscape of genomics and molecular biology. The first human genome sequence, with its revelations on gene number and relatively low human genetic diversity, was shortly followed by extensive investigation of single nucleotide polymorphisms in our DNA and, with the help of more and more complex SNP arrays, by extensive whole-genome association studies (GWAS). These have uncovered many gene/phenotype correlations, but have also revealed how limited our understanding of the functional genome still is. The importance of non-coding transcripts and of epigenetic modifications of our DNA has been realised. And very recently, DNA sequencing technology has made tremendous progress, to the point that the 1,000-dollar genome is in sight and that clinical use of whole-genome or exome sequencing is becoming significant (and is in fact competing with some uses of arrays). Meanwhile, clinical applications of DNA microarrays have developed, but not exactly in the directions anticipated 10 years ago and not quite at the level predicted by some analysts. Other microarrays using proteins, antibodies, peptide, or aptamer molecules as probes have made significant advances in spite of technical problems, and now have an impact not only in research but also in the clinic and in biomarker development. This new book includes 13 main chapters, and covers essentially all types of arrays. It is focussed on entities that are in actual clinical use, or quite close to it thus it does not discuss, for example, complex SNP arrays that remain essentially a research tool. It does present some very recent developments, such as peptide or aptamer arrays, or also miniaturisation towards nanoarrays, that I see as having great potential in medicine even though their current presence is still limited. It discusses in detail very important issues in bioinformatics and in statistical analysis of array data, as well as the hurdles faced in the commercialisation of array-based tests and the vexing IP issues associated with these activities. v
6 vi Preface I believe this book will be useful to current array users who wish to have a complete view of the field, to newcomers who attempt to make the best choice between different technologies, and to academic scientists who engage in technology transfer activities and need to evaluate the hurdles involved in this process. I am especially grateful to the authors, my colleagues, who kindly accepted to undertake the absorbing task of writing a chapter, especially at a time where tight funding means that they are extremely busy preparing grant applications. And, of course, the organisational support from Springer to overcome the 1,001 small problems encountered in the production of this book is gratefully acknowledged. Marseille, France
7 Contents 1 The Microarray Paradigm and Its Various Implementations... 1 Part I DNA Arrays 2 DNA Arrays in Many Guises Expression Profiling for Diagnostics Genotype Characterisation for Diagnostics Array-CGH and SNP-Arrays, the New Karyotype Karoly Szuhai Part II Protein (Antigen and Antibody) and Peptide Arrays 6 Protein Microarrays and Their Potential Clinical Applications in the Era of Personalized Medicine Hong Zhang and Steven Pelech 7 Peptide Arrays Hong Zhang, Steven Pelech, Rob Ruijtenbeek, Thomas Felgenhauer, Ralf Bischoff, Frank Breitling, and Volker Stadler 8 Slow Off-Rate Modified Aptamer Arrays for Biomarker Discovery and Diagnostic Applications Jeffrey J. Walker, Edward N. Brody, and Larry Gold vii
8 viii Contents Part III Other Types of Arrays 9 Tissue Microarrays for Translational Research Ronald Simon and Martina Mirlacher 10 Recent and Future Developments of Microarrays: Miniaturization and Lab-on-Chip Approaches Inbal Tsarfati-BarAd and Levi A. Gheber Part IV Data Analysis, Commercial and Regulatory Aspects 11 Analysis of Array Data and Clinical Validation of Array-Based Assays Benjamin Haibe-Kains and John Quackenbush 12 Challenges in the Commercialization of Array-Based Tests Justin Petrone 13 Genes, Microarrays, and Patents Justin Petrone Concluding Remarks Index
Agile Project Management: Managing for Success
Agile Project Management: Managing for Success James A. Crowder Shelli Friess Agile Project Management: Managing for Success James A. Crowder Raytheon Denver, CO, USA Shelli Friess Englewood, CO, USA
More informationJinsong Zhou Zhongyang Luo Yanqun Zhu Mengxiang Fang. Mercury Emission and its Control in Chinese Coal-Fired Power Plants
Jinsong Zhou Zhongyang Luo Yanqun Zhu Mengxiang Fang Mercury Emission and its Control in Chinese Coal-Fired Power Plants Jinsong Zhou Zhongyang Luo Yanqun Zhu Mengxiang Fang Mercury Emission and its Control
More informationLecture Notes in Energy 5
Lecture Notes in Energy 5 For further volumes: http://www.springer.com/series/8874 . Hortensia Amaris Monica Alonso Carlos Alvarez Ortega Reactive Power Management of Power Networks with Wind Generation
More informationGenetic and Molecular Epidemiology of Multiple Myeloma
Genetic and Molecular Epidemiology of Multiple Myeloma Suzanne Lentzsch Editor Genetic and Molecular Epidemiology of Multiple Myeloma Editor Suzanne Lentzsch College of Physicians and Surgeons Multiple
More informationEthics for Biomedical Engineers
Ethics for Biomedical Engineers Jong Yong Abdiel Foo Stephen J. Wilson Andrew P. Bradley Winston Gwee Dennis Kwok-Wing Tam Ethics for Biomedical Engineers Jong Yong Abdiel Foo Electronic and Computer
More informationThe Genetics of Obesity
The Genetics of Obesity Struan F.A. Grant Editor The Genetics of Obesity Editor Struan F.A. Grant Children s Hospital of Philadelphia Research Institute Philadelphia, PA, USA ISBN 978-1-4614-8641-1 ISBN
More informationShabbir A. Shahid Mahmoud A. Abdelfattah Michael A. Wilson John A. Kelley Joseph V. Chiaretti. United Arab Emirates Keys to Soil Taxonomy
Shabbir A. Shahid Mahmoud A. Abdelfattah Michael A. Wilson John A. Kelley Joseph V. Chiaretti United Arab Emirates Keys to Soil Taxonomy United Arab Emirates Keys to Soil Taxonomy Shabbir A. Shahid Mahmoud
More informationLecture Notes in Earth System Sciences 144
Lecture Notes in Earth System Sciences 144 Editors: P. Blondel, Bath J. Reitner, G ottingen K. St uwe, Graz M.H. Trauth, Potsdam D. Yuen, Minneapolis Founding Editors: G. M. Friedman, Brooklyn and Troy
More informationRecombinant Enzymes From Basic Science to Commercialization
Recombinant Enzymes From Basic Science to Commercialization Azura Amid Editor Recombinant Enzymes From Basic Science to Commercialization 1 3 Editor Azura Amid Department of Biotechnology Engineering Kulliyyah
More informationSpringerBriefs in Food, Health, and Nutrition Series
SpringerBriefs in Food, Health, and Nutrition Series Springer Briefs in Food, Health, and Nutrition present concise summaries of cutting edge research and practical applications across a wide range of
More informationMohamad Mohty Jean-Luc Harousseau. Handbook of Multiple Myeloma. Springer
Mohamad Mohty Jean-Luc Harousseau Handbook of Multiple Myeloma Mohamad Mohty Jean-Luc Harousseau Handbook of Multiple Myeloma Mohamad Mohty, MD, PhD Université Pierre and Marie Curie Hospital Saint-Antoine
More informationLecture Notes in Management and Industrial Engineering
Lecture Notes in Management and Industrial Engineering Volume 1 Series Editor: Adolfo López-Paredes Valladolid, Spain This bookseries provides a means for the dissemination of current theoretical and applied
More informationChapter 3: Assessing and Measuring Wetland Hydrology
Chapter 3: Assessing and Measuring Wetland Hydrology Donald O. Rosenberry and Masaki Hayashi This sample file is posted on the web site for preliminary viewing of contents. If you would like to have a
More informationDesign and Management of Energy-Efficient Hybrid Electrical Energy Storage Systems
Design and Management of Energy-Efficient Hybrid Electrical Energy Storage Systems Younghyun Kim Naehyuck Chang Design and Management of Energy-Efficient Hybrid Electrical Energy Storage Systems 123 Younghyun
More informationThe Search for Human Chromosomes
The Search for Human Chromosomes ThiS is a FM Blank Page Wilson John Wall The Search for Human Chromosomes A History of Discovery Wilson John Wall Bewdley United Kingdom ISBN 978-3-319-26334-2 ISBN 978-3-319-26336-6
More informationLeading Pharmaceutical Operational Excellence
Leading Pharmaceutical Operational Excellence ThiS is a FM Blank Page Thomas Friedli Prabir Basu Daniel Bellm Jürgen Werani Editors Leading Pharmaceutical Operational Excellence Outstanding Practices and
More informationManagement for Professionals
Management for Professionals For further volumes: http://www.springer.com/series/10101 ThiS is a FM Blank Page Erik Jannesson Fredrik Nilsson Birger Rapp Editors Strategy, Control and Competitive Advantage
More informationManagement of Permanent Change
Management of Permanent Change Horst Albach Heribert Meffert Andreas Pinkwart Ralf Reichwald Editors Management of Permanent Change Editors Horst Albach Center for Advanced Studies in Management HHL Leipzig
More informationLeading with Emotional Intelligence
Leading with Emotional Intelligence Malcolm Higgs Victor Dulewicz Leading with Emotional Intelligence Effective Change Implementation in Today s Complex Context Malcolm Higgs Southampton Business School
More informationManganese in Powder Metallurgy Steels
Manganese in Powder Metallurgy Steels Andrej Šalak Marcela Selecká Manganese in Powder Metallurgy Steels 123 Andrej Šalak Institute of Materials Research Slovak Academy of Sciences Kosice Slovakia Marcela
More informationSustainable Agriculture Reviews
Sustainable Agriculture Reviews Volume 12 Series Editor Eric Lichtfouse For further volumes: http://www.springer.com/series/8380 Other Books by Dr. Eric Lichtfouse* Sustainable Agriculture Sustainable
More informationSimulation Strategies to Reduce Recidivism
Simulation Strategies to Reduce Recidivism Faye S. Taxman April Pattavina Editors Simulation Strategies to Reduce Recidivism Risk Need Responsivity (RNR) Modeling for the Criminal Justice System Editors
More informationManagement for Professionals
Management for Professionals For further volumes: http://www.springer.com/series/10101 ThiS is a FM Blank Page Akram Al Ariss Editor Global Talent Management Challenges, Strategies, and Opportunities Editor
More informationManaging e-business Projects
Managing e-business Projects Springer-Verlag Berlin Heidelberg GmbH Thomas Stoehr Managing e-business Projects 99 Key Success Factors With 37 Figures and 12 Tables Springer Thomas Stoehr Overbeckstr. 7
More informationGreen Energy and Technology
Green Energy and Technology For further volumes: http://www.springer.com/series/8059 Eric Johnson Sustainability in the Chemical Industry Eric Johnson Atlantic Consulting Obstgartenstrasse 14 8136 Gattikon
More informationEnergy-Efficient HVAC Design
Energy-Efficient HVAC Design Javad Khazaii Energy-Efficient HVAC Design An Essential Guide for Sustainable Building Javad Khazaii Engineering Department Southern Polytechnic State University Marietta,
More informationLivelihood Strategies in Southern India
Livelihood Strategies in Southern India Seema Purushothaman Rosa Abraham Editors Livelihood Strategies in Southern India Conservation and Poverty Reduction in Forest Fringes Editors Seema Purushothaman
More informationGroundwater Pollution Risk Control from an Industrial Economics Perspective
Groundwater Pollution Risk Control from an Industrial Economics Perspective Huan Huan Jianwei Xu Jinsheng Wang Beidou Xi Groundwater Pollution Risk Control from an Industrial Economics Perspective A Case
More informationJob Demands in a Changing World of Work
Job Demands in a Changing World of Work A word cloud of the contents of the book Christian Korunka Bettina Kubicek Editors Job Demands in a Changing World of Work Impact on Workers Health and Performance
More informationMicrosystems for Pharmatechnology
Microsystems for Pharmatechnology Andreas Dietzel Editor Microsystems for Pharmatechnology Manipulation of Fluids, Particles, Droplets, and Cells Editor Andreas Dietzel Institute of Microtechnology Technische
More informationDiversity Intelligence
Diversity Intelligence Claretha Hughes Diversity Intelligence Integrating Diversity Intelligence alongside Intellectual, Emotional, and Cultural Intelligence for Leadership and Career Development Claretha
More informationAccess to Justice in Transnational B2C E-Commerce
Access to Justice in Transnational B2C E-Commerce ThiS is a FM Blank Page Sutatip Yuthayotin Access to Justice in Transnational B2C E-Commerce A Multidimensional Analysis of Consumer Protection Mechanisms
More informationMatrix-Based Product Design and Change Management
Matrix-Based Product Design and Change Management Dunbing Tang Leilei Yin Inayat Ullah Matrix-Based Product Design and Change Management 123 Dunbing Tang College of Mechanical and Electrical Engineering
More informationLogistic Core Operations with SAP
Logistic Core Operations with SAP . Jens Kappauf l Matthias Koch Bernd Lauterbach Logistic Core Operations with SAP Inventory Management, Warehousing, Transportation, and Compliance Jens Kappauf SAP AG,
More informationSand Control in Well Construction and Operation
Sand Control in Well Construction and Operation Springer Environmental Science and Engineering For further volumes: http://www.springer.com/series/10177 Davorin Matanović l Bojan Moslavac Marin Čikeš l
More informationMeta-heuristic Algorithms for Optimal Design of Real-Size Structures
Meta-heuristic Algorithms for Optimal Design of Real-Size Structures Ali Kaveh Majid Ilchi Ghazaan Meta-heuristic Algorithms for Optimal Design of Real-Size Structures 123 Ali Kaveh Department of Civil
More informationSpringerBriefs in Operations Management
SpringerBriefs in Operations Management Series Editor Suresh P. Sethi The University of Texas at Dallas, TX, USA More information about this series at http://www.springer.com/series/13082 Petri Helo Angappa
More informationPharmaceutical Prices in the 21st Century
Pharmaceutical Prices in the 21st Century ThiS is a FM Blank Page Zaheer-Ud-Din Babar Editor Pharmaceutical Prices in the 21st Century Editor Zaheer-Ud-Din Babar Faculty of Medical and Health Sciences
More informationUsing Microsoft Dynamics AX 2012
Using Microsoft Dynamics AX 2012 Andreas Luszczak Using Microsoft Dynamics AX 2012 Updated for Version R2 3rd Edition Dr. Andreas Luszczak Vienna, Austria ISBN 978-3-658-01708-8 DOI 10.1007/978-3-658-01709-5
More informationEnvironmental Sustainability Issues in the South Texas Mexico Border Region
Environmental Sustainability Issues in the South Texas Mexico Border Region David Ramirez Jianhong Ren Kim D. Jones Harriet Lamm Editors Environmental Sustainability Issues in the South Texas Mexico Border
More informationTopics in Mining, Metallurgy and Materials Engineering. Series editor Carlos P. Bergmann, Porto Alegre, Brazil
Topics in Mining, Metallurgy and Materials Engineering Series editor Carlos P. Bergmann, Porto Alegre, Brazil Topics in Mining, Metallurgy and Materials Engineering welcomes manuscripts in these three
More informationEngineering Materials and Processes. Series editor Brian Derby, Manchester, UK
Engineering Materials and Processes Series editor Brian Derby, Manchester, UK More information about this series at http://www.springer.com/series/4604 Rasheedat Modupe Mahamood Laser Metal Deposition
More informationTree and Forest Measurement
Tree and Forest Measurement P.W. West Tree and Forest Measurement 2 nd Edition With 33 Figures and 11 Tables P.W. West School of Environmental Science and Management Southern Cross University Lismore,
More informationMitsuru Kodama. Boundary Management. Developing Business Architectures for Innovation
Boundary Management Mitsuru Kodama Boundary Management Developing Business Architectures for Innovation 123 Mitsuru Kodama, Ph.D. Professor of Information and Management College of Commerce and Graduate
More informationHandbook of Media Branding
Handbook of Media Branding ThiS is a FM Blank Page Gabriele Siegert Kati F orster Sylvia M. Chan-Olmsted Mart Ots Editors Handbook of Media Branding Editors Gabriele Siegert University of Zurich IPMZ Institute
More informationProject Management for Facility Constructions
Project Management for Facility Constructions Alberto De Marco Project Management for Facility Constructions A Guide for Engineers and Architects 123 Alberto De Marco Politecnico di Torino Department
More informationTextile Science and Clothing Technology. Series editor Subramanian Senthilkannan Muthu, Hong Kong, Kowloon, Hong Kong
Textile Science and Clothing Technology Series editor Subramanian Senthilkannan Muthu, Hong Kong, Kowloon, Hong Kong More information about this series at http://www.springer.com/series/13111 Subramanian
More informationService Business Costing
Service Business Costing Markus B. Baum Service Business Costing Cost Accounting Approach for the Service Industry Foreword by Dr. Kerry Sullivan RESEARCH Markus B. Baum Mainz, Germany MBA Dissertation,
More informationProceedings of Selected Articles of 2013 World Agricultural Outlook Conference
Proceedings of Selected Articles of 2013 World Agricultural Outlook Conference ThiS is a FM Blank Page Shiwei Xu Editor Proceedings of Selected Articles of 2013 World Agricultural Outlook Conference Editor
More informationFundamentals of Pediatric Drug Dosing
Fundamentals of Pediatric Drug Dosing Gilbert Burckart Editors Fundamentals of Pediatric Drug Dosing Editors Clinical Pharmacology/Biopharmaceutics Food & Drug Administration Silver Spring Maryland USA
More informationThe Greek Economy and the Crisis
The Greek Economy and the Crisis . Panagiotis Petrakis The Greek Economy and the Crisis Challenges and Responses Prof. Panagiotis Petrakis National and Kapodistrian University of Athens Department of Economics
More information158 Advances in Biochemical Engineering/Biotechnology
158 Advances in Biochemical Engineering/Biotechnology Series editor T. Scheper, Hannover, Germany Editorial Board S. Belkin, Jerusalem, Israel T. Bley, Dresden, Germany J. Bohlmann, Vancouver, Canada M.B.
More informationEnergy Systems. Series Editor: Panos M. Pardalos, University of Florida, USA. For further volumes:
Energy Systems Series Editor: Panos M. Pardalos, University of Florida, USA For further volumes: http://www.springer.com/series/8368 . Alexey Sorokin l Steffen Rebennack l Panos M. Pardalos l Niko A. Iliadis
More informationCyanobacteria for Bioremediation of Wastewaters
Cyanobacteria for Bioremediation of Wastewaters Inga Zinicovscaia Liliana Cepoi Editors Cyanobacteria for Bioremediation of Wastewaters Editors Inga Zinicovscaia Joint Institute for Nuclear Research,
More informationResults and Problems in Cell Differentiation
Results and Problems in Cell Differentiation 51 Series Editors Dietmar Richter, Henri Tiedge Roland Martin Andreas Lutterotti (eds.) Molecular Basis of Multiple Sclerosis The Immune System Editors Roland
More informationAdvances in Experimental Medicine and Biology
Advances in Experimental Medicine and Biology Editorial Board: IRUN R. COHEN, The Weizmann Institute of Science, Rehovot, Israel ABEL LAJTHA, N.S. Kline Institute for Psychiatric Research, Orangeburg,
More informationInnovation and Marketing in the Pharmaceutical Industry
Innovation and Marketing in the Pharmaceutical Industry For further volumes: http://www.springer.com/series/6164 Series Editor Jehoshua Eliashberg The Wharton School University of Pennsylvania 700 Jon
More informationSegmentation in Social Marketing
Segmentation in Social Marketing Timo Dietrich Sharyn Rundle-Thiele Krzysztof Kubacki Editors Segmentation in Social Marketing Process, Methods and Application 123 Editors Timo Dietrich Krzysztof Kubacki
More informationSpringerBriefs in Microbiology
SpringerBriefs in Microbiology For further volumes: http://www.springer.com/series/8911 Naowarat Cheeptham Editor Cave Microbiomes: A Novel Resource for Drug Discovery Editor Naowarat Cheeptham Thompson
More informationDemand Driven Supply Chain
Demand Driven Supply Chain . Paulo Mendes Jr. Demand Driven Supply Chain A Structured and Practical Roadmap to Increase Profitability Paulo Mendes Jr. Catholic University Industrial Engineering Department
More informationProgress in IS. For further volumes:
Progress in IS For further volumes: http://www.springer.com/series/10440 Gino Brunetti Thomas Feld Lutz Heuser Joachim Schnitter Christian Webel Editors Future Business Software Current Trends in Business
More informationFamilienunternehmen und KMU
Familienunternehmen und KMU Edited by A. Hack, Berne A. Calabrò, Witten/Herdecke H. Frank, Vienna F. W. Kellermanns, Tennessee T. Zellweger, St. Gallen Both Family Firms and Small and Medium Sized Enterprises
More informationClinical Pharmacology: Current Topics and Case Studies
Clinical Pharmacology: Current Topics and Case Studies Markus Müller Editor Clinical Pharmacology: Current Topics and Case Studies Second Edition Editor Markus Müller Universitätsklinik für Klinische
More informationTextile Science and Clothing Technology. Series editor Subramanian Senthilkannan Muthu, Kowloon, Hong Kong
Textile Science and Clothing Technology Series editor Subramanian Senthilkannan Muthu, Kowloon, Hong Kong More information about this series at http://www.springer.com/series/13111 Subramanian Senthilkannan
More informationSAP Excellence. Series Editors: Professor Dr. Dr. h.c. mult. Peter Mertens Universität Erlangen-Nürnberg. Dr. Peter Zencke SAP AG, Walldorf
SAP Excellence Series Editors: Professor Dr. Dr. h.c. mult. Peter Mertens Universität Erlangen-Nürnberg Dr. Peter Zencke SAP AG, Walldorf Jörg Thomas Dickersbach Characteristic Based Planning with mysap
More informationThe Economics of Evaluating Water Projects
The Economics of Evaluating Water Projects i Per-Olov Johansson Bengt Kriström The Economics of Evaluating Water Projects Hydroelectricity Versus Other Uses 123 Prof. Per-Olov Johansson Stockholm School
More informationStrategy and Organization of Corporate Banking
Strategy and Organization of Corporate Banking Giacomo De Laurentis (Editor) Strategy and Organization of Corporate Banking With 12 Figures and 49 Tables 4y Springer Professor Giacomo De Laurentis Institute
More informationAdenovirus Epithelial Keratitis and Thygeson s Superficial Punctate Keratitis
Adenovirus Epithelial Keratitis and Thygeson s Superficial Punctate Keratitis Helena M. Tabery Adenovirus Epithelial Keratitis and Thygeson s Superficial Punctate Keratitis In Vivo Morphology in the Human
More informationTowards an Effective European Single Market
Towards an Effective European Single Market Michael Kaeding Towards an Effective European Single Market Implementing the Various Forms of European Policy Instruments across Member States Michael Kaeding
More informationInformation Systems for Engineering and Infrastructure Asset Management
Information Systems for Engineering and Infrastructure Asset Management Abrar Haider Information Systems for Engineering and Infrastructure Asset Management Foreword by Professor Andy Koronios RESEARCH
More informationUrban and Regional Research International Volume 14
Urban and Regional Research International Volume 14 Edited by H. Wollmann, Berlin, Germany H. Baldersheim, Oslo, Norwey P. John, London, United Kingdom Editorial Board S. Clarke, Boulder, USA V. Hoffmann-Martinot,
More informationSustainable Water Resources Planning and Management Under Climate Change
Sustainable Water Resources Planning and Management Under Climate Change Elpida Kolokytha Satoru Oishi Editors Sustainable Water Resources Planning and Management Under Climate Change 123 Editors Elpida
More informationIntegrated Business Model
essentials Oliver D. Doleski Integrated Business Model Applying the St. Gallen Management Concept to Business Models Oliver D. Doleski Munich Germany ISSN 2197-6708 essentials ISBN 978-3-658-09697-7 DOI
More informationApplied Conjoint Analysis
Applied Conjoint Analysis . Vithala R. Rao Applied Conjoint Analysis Vithala R. Rao S. C. Johnson Graduate School of Management Cornell University Ithaca, New York USA ISBN 978-3-540-87752-3 ISBN 978-3-540-87753-0
More informationPublic Administration, Governance and Globalization
Public Administration, Governance and Globalization Volume 16 Series Editor Ali Farazmand Florida Atlantic University Fort Lauderdale Florida USA Public Administration, Governance and Globalization Ali
More informationSpecificity of Proteolysis
Borivoj Keil Specificity of Proteolysis With 17 Figures and 20 Tables Springer-Verlag Berlin Heidelberg New York London Paris Tokyo Hong Kong Barcelona Budapest Prof. Dr. Borivoj Keil Institut Pasteur
More informationCustomer Relationship Management
Customer Relationship Management Springer-Verlag Berlin Heidelberg GmbH Federico Rajola Customer Relationship Management Organizational and Technological Perspectives With 37 Figures and 13 Tables Springer
More informationKnowledge Capture in Financial Regulation
Knowledge Capture in Financial Regulation Eva Becker Knowledge Capture in Financial Regulation Data-, Information- and Knowledge- Asymmetries in the US Financial Crisis Eva Becker München, Deutschland
More informationData Mining and Applications in Genomics
Data Mining and Applications in Genomics Lecture Notes in Electrical Engineering Volume 25 For other titles published in this series, go to www.springer.com/series/7818 Sio-Iong Ao Data Mining and Applications
More informationChanging Innovation in the Pharmaceutical Industry. Globalization and New Ways of Drug Development
Changing Innovation in the Pharmaceutical Industry Globalization and New Ways of Drug Development Springer-Verlag Berlin Heidelberg GmbH Andre Jungmittag Guido Reger Thomas Reiss (Eds.) Changing Innovation
More informationGenome Analysis and Human Health
Genome Analysis and Human Health Leena Rawal Sher Ali Editors Genome Analysis and Human Health Editors Leena Rawal Department of Cytogenetics National Reference Laboratory Dr Lal PathLabs New Delhi India
More informationTransforming Rural Communities in China and Beyond
Transforming Rural Communities in China and Beyond Ying Zhu Hong Lan David A. Ness Ke Xing Kris Schneider Seung-Hee Lee Jing Ge Transforming Rural Communities in China and Beyond Community Entrepreneurship
More informationEcoProduction. Environmental Issues in Logistics and Manufacturing
EcoProduction. Environmental Issues in Logistics and Manufacturing For further volumes: http://www.springer.com/series/10152 About the Series The EcoProduction Series is a forum for presenting emerging
More informationManagement of Network Organizations
Management of Network Organizations ThiS is a FM Blank Page Włodzimierz Sroka Štefan Hittmár Editors Management of Network Organizations Theoretical Problems and the Dilemmas in Practice Editors Włodzimierz
More informationEnterprise Risk Management Models
Enterprise Risk Management Models David L. Olson Desheng Wu Enterprise Risk Management Models 123 Professor David L. Olson University of Nebraska Department of Management Lincoln, NE 68588-0491 USA dolson3@unl.edu
More informationUsing Microsoft Dynamics AX 2012
Using Microsoft Dynamics AX 2012 Understanding IT Autonomous Land Vehicles by Karsten Berns an Ewald von Puttkamer Microsoft Dynamics NAV by Paul M. Diffenderfer and Samir El-Assal jr. Future of Trust
More informationMohammad Aslam Khan Khalil (Ed.) Atmospheric Methane
Mohammad Aslam Khan Khalil (Ed.) Atmospheric Methane Springer-Verlag Berlin Heidelberg GmbH Mohammad Aslam Khan Khalil (Ed.) Atmospheric Methane Its Role in the Global Environment With 61 Figures and 49
More informationPublic Sector Organizations
Public Sector Organizations Series Editors B. Guy Peters Pittsburgh University, USA Geert Bouckaert Katholieke Universiteit Leuven, Belgium Aims of the Series Organizations are the building blocks of governments.
More informationManaging Your. Provider
Managing Your Outsourced IT Services Provider How to Unleash the Full Potential of Your Global Workforce Venkatesh Upadrista Managing Your Outsourced IT Services Provider: How to Unleash the Full Potential
More informationCurrent Topics in Environmental Health and Preventive Medicine. Series editor T. Otsuki Kurashiki, Japan
Current Topics in Environmental Health and Preventive Medicine Series editor T. Otsuki Kurashiki, Japan Current Topics in Environmental Health and Preventive Medicine, published in partnership with the
More informationDeformation Compatibility Control for Engineering Structures
Deformation Compatibility Control for Engineering Structures Hanhua Zhu Zhihui Zhou Mengchong Chen Jianliang Deng Deformation Compatibility Control for Engineering Structures Methods and Applications 123
More informationChanging Contours of Indian Agriculture
Changing Contours of Indian Agriculture Seema Bathla Amaresh Dubey Editors Changing Contours of Indian Agriculture Investment, Income and Non-farm Employment 123 Editors Seema Bathla Centre for the Study
More informationAdvances in Agroforestry
Advances in Agroforestry Volume 10 Series Editor P. K. Ramachandran Nair, Gainesville, USA For further volumes: http://www.springer.com/series/6904 Aims and Scope Agroforestry, the purposeful growing of
More informationFamilienunternehmen und KMU
Familienunternehmen und KMU Series editor A. Hack, Bern, Switzerland A. Calabrò, Witten, Germany T. Zellweger, St. Gallen, Switzerland F.W. Kellermanns, Charlotte, USA H. Frank, Wien, Austria Both Family
More informationHandbook of Experimental Pharmacology
Handbook of Experimental Pharmacology Volume 229 Editor-in-Chief W. Rosenthal, Jena Editorial Board J.E. Barrett, Philadelphia V. Flockerzi, Homburg M.A. Frohman, Stony Brook, NY P. Geppetti, Florence
More informationEssentials of Administering Team Foundation Server 2015
Essentials of Administering Team Foundation Server 2015 Using TFS 2015 to Accelerate Your Software Development Gary Gauvin Essentials of Administering Team Foundation Server 2015: Using TFS 2015 to Accelerate
More informationWheat Diseases and Their Management
Wheat Diseases and Their Management Yeshwant Ramchandra Mehta Wheat Diseases and Their Management Yeshwant Ramchandra Mehta Instituto Agronômico do Paraná - IAPAR Londrina, Paraná, Brazil ISBN 978-3-319-06464-2
More informationAnne König. Internet-Based Services and Processes. With 91 Figures and 4 Tables
Anne König E-Business @Print Internet-Based Services and Processes With 91 Figures and 4 Tables 123 Anne König Technische Fachhochschule Berlin University of Applied Sciences Luxemburger Str. 10 13353
More informationRecent Advances in Stored Product Protection
Recent Advances in Stored Product Protection Christos G. Athanassiou Frank H. Arthur Editors Recent Advances in Stored Product Protection 123 Editors Christos G. Athanassiou Laboratory of Entomology and
More informationHuman Resource Management in Consulting Firms
Human Resource Management in Consulting Firms Michel E. Domsch Elena Hristozova (Editors) Human Resource Management in Consulting Firms With 42 Figures 12 Professor Dr. Michel E. Domsch Dipl.-Oec. Elena
More information