GLOBAL DIAGNOSTICS 1
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1 GLOBAL DIAGNOSTICS 1
2 Features Accurate Extended shelf-life Room temperature storage Affordable Flexible Simple Rapid results Benefits Highly sensitive and specific results, delivered through proven technology Confidently eliminate lost revenue on expired test kits Save fridge space and eliminate test warm-up time, while guaranteeing rapid results for your patients Pass on the savings to your clients and eliminate the cost of babysitting multi-step, overpriced test kits Embrace the flexibility of single testing based on clinical symptoms and disease prevalence specific to your geographic location Three easy steps help eliminate unnecessary re-tests and minimize the margin for human error Get results at the point-of-care in 8-10 minutes 2
3 Providing the flexibility you need at the point-of-care The VetScan Rapid Test portfolio gives you more of what you want and less of what you don t need. Now you have more options, more confidence, less hassle and less waiting. VetScan Rapid Tests deliver exactly what you ve come to know from Abaxis. It s the perfect balance of price and performance. Table of Contents VetScan VUE 4 VetScan cpl Rapid Test 8 VetScan FeLV/FIV Rapid Test 10 VetScan Heartworm Rapid Test 12 VetScan Ehrlichia Rapid Test 14 VetScan Lyme Rapid Test 16 VetScan Anaplasma Rapid Test 18 VetScan Parvo Rapid Test 20 VetScan Giardia Rapid Test 22 Test Accuracy 24 Lateral Flow Technology 26 3
4 Rapid Test Analyzer VUE 4
5 An innovative approach to point-of-care testing right from your mobile device. The VetScan VUE utilizes Wi-Fi technology to enable an automated process to Rapid testing at the point-of-care. Simply said, you can use the VetScan Rapid Test the way you normally do, or use the VetScan VUE to scan, interpret, and share the results.* The future of veterinary medicine... Today. Download. Test. Read. Share. The VUE can be operated from an ios or Android mobile device. Simply download the app, connect to the VUE, perform a test, and share the result. It s that simple. * The VetScan cpl Rapid Test must be performed with the VetScan VUE. 5
6 A Veterinary Technician s Best Friend With your clinic s demanding schedule and workload, it s becoming more important to have lab devices that make everyone s job easier. The VetScan VUE s integrated timer and autoread functions do just that. Simple Operation Quick Scan Timed Scan For multiple tests on a single patient, use the Quick Scan Mode to scan additional tests in seconds without re-entering patient information multiple times. Quick Scan Mode works well when using the entire VetScan Rapid Test menu and with busy practice workflows. Timed Scan Mode let s the VUE do the work for you. Simply perform your test, insert it into the cassette holder, and let your VUE s integrated timer and auto interpretation take over. In 10 minutes, you ll be notified with your results on your mobile device. 6
7 Features Benefits App-based platform Operate the VUE from an ios or Android mobile device Automated test interpretation Get accurate, reproducible results consistent with visual reads, without operator subjectivity Integrated timer The Rapid Test is scanned for a result on time, every time, ensuring a read time is never missed Flexible Use all single or combo VetScan Rapid Tests in two different scan modes to meet the needs of practice workflow No maintenance Innovative design eliminates any need for time-consuming maintenance Small footprint The small footprint makes it a welcome addition to any clinic s lab station Connectivity With a Wi-Fi access point, the VUE can the results to the patient or practice. 7
8 cpl Rapid Test cpl 8
9 Read with cpl Rapid Test The Abaxis VetScan Canine Pancreatic Lipase (cpl) Rapid Test is a highly sensitive and specific semi-quantitative immunoassay for the detection of pancreas-specific lipase in canine serum or plasma. 10 Must be read with the VetScan VUE Room temperature storage Available in 10 test kit Test Instructions Add 1 drop of serum Add 3 drops of Chase or plasma to the Buffer to the sample sample well. well. Insert cassette into VUE. Initiate a Timed Scan in the VUE app. Check mobile device display for numeric result when timer completes. Read with cpl Read with cpl cpl 9
10 FeLV/FIV Rapid Test FeLV/ FIV 10
11 FeLV/FIV Rapid Test The Abaxis VetScan FeLV/FIV Rapid Test is a highly sensitive and specific test for the qualitative detection of Feline Leukemia Virus antigen and Feline Immunodeficiency Virus antibodies in feline whole blood, serum, or plasma. TESTS PER BOX Read within 10 minutes Room temperature storage Available in 10 test kit & 25 test kit Test Instructions FeLV FIV Add 3 drops of the designated Chase Add 1 drop of anticoagulated whole blood, serum or plasma to each sample well and wait 5-10 seconds. Buffer to its respective sample well. Read results within 10 minutes. FIV Positive Example 11
12 Heartworm Rapid Test Heartworm 12
13 Heartworm Rapid Test The Abaxis VetScan Heartworm Rapid Test is a highly sensitive and specific test for the qualitative detection of Dirofilaria immitis antigen in canine and feline whole blood, serum or plasma. TESTS PER BOX Read within 10 minutes Room temperature storage Available in 25 test kit & 100 test kit Test Instructions Add 1 drop of Add 2 drops of Chase anticoagulated Buffer to the whole blood, serum or plasma to the sample well and wait 3-5 seconds. sample well. Read results within 10 minutes. Positive Example 13
14 Ehrlichia Rapid Test Ehrlichia 14
15 Canine Ehrlichia Rapid Test The Abaxis VetScan Canine Ehrlichia Rapid Test is a highly sensitive and specific test for the qualitative detection of antibodies to E. canis, E. chaffeensis, and E. ewingii in canine whole blood, serum, or plasma. TESTS PER BOX 25 Read within 8-10 minutes Room temperature storage Available in 25 test kit Test Instructions 1 Add 1 drop of anticoagulated whole blood, serum or plasma to the sample well and wait seconds. 2 Add 3 drops of Chase Buffer to the 3 sample well. Read results within 8 to 10 minutes. Positive Example 15
16 Canine Lyme Rapid Test Lyme 16
17 Canine Lyme Rapid Test The Abaxis VetScan Canine Lyme Rapid Test is a highly sensitive and specific test for the qualitative detection of antibodies to Borrelia burgdorferi in canine whole blood, serum or plasma. TESTS PER BOX 25 Read within 8-10 minutes Room temperature storage Available in 25 test kit Test Instructions 1 Add 1 drop of anticoagulated whole blood, serum or plasma to the sample well and wait seconds. 2 Add 3 drops of Chase Buffer to the 3 sample well. Read results within 8 to 10 minutes. Positive Example 17
18 Canine Anaplasma Rapid Test Anaplasma 18
19 Canine Anaplasma Rapid Test The Abaxis VetScan Canine Anaplasma Rapid Test is a highly sensitive and specific test for the qualitative detection of antibodies to A. phagocytophilum and/or A. platys in canine whole blood, serum, or plasma. TESTS PER BOX 25 Read within 8-10 minutes Room temperature storage Available in 25 test kit Test Instructions 1 Add 1 drop of anticoagulated whole blood, serum or plasma to the sample well and wait seconds. 2 Add 3 drops of Chase Buffer to the 3 sample well. Read results within 8 to 10 minutes. Positive Example 19
20 Canine Parvo Rapid Test Parvo 20
21 Canine Parvo Rapid Test The Abaxis VetScan Canine Parvovirus Rapid Test is a highly sensitive and specific test for the qualitative detection of Parvovirus antigens in canine feces. Fecal Sample Collection Guide Read within minutes Room temperature storage Available in 10 test kit & 20 test kit The sample amount The swab is coated is insufficient and not uniformly with a thin recommended for testing. layer of sample. It is recommended to use this amount of fecal sample for testing. The sample amount is excessive and not recommended for testing. Fecal Test Instructions Dilute Sample Load Diluted Coat the swab uniformly with a thin layer of sample. Break the seal to release sample diluent. Squeeze the bulb 5 6 times to completely mix the sample. Sample Transfer 3 drops of sample into the sample well. Read Results Read results within 10 minutes. Positive Example 21
22 Canine Giardia Rapid Test Giardia 22
23 Canine Giardia Rapid Test The Abaxis VetScan Giardia Rapid Test is a highly sensitive and specific test for the qualitative detection of Giardia cyst antigens in canine feces. Fecal Sample Collection Guide Read within minutes Room temperature storage Available in 10 test kit & 20 test kit The sample amount The swab is coated is insufficient and not uniformly with a thin recommended for testing. layer of sample. It is recommended to use this amount of fecal sample for testing. The sample amount is excessive and not recommended for testing. Fecal Test Instructions Dilute Sample Load Diluted Coat the swab uniformly with a thin layer of sample. Break the seal to release sample diluent. Squeeze the bulb 5 6 times to completely mix the sample. Sample Transfer 3 drops of sample into the sample well. Read Results Read results within 10 minutes. Positive Example 23
24 24 Test Accuracy
25 Sensitivity How accurately the test can identify pets that have a specific disease. Specificity How accurately the test can identify pets that don t have a specific disease. Test Sensitivity Specificity Species Test Type Standard Heartworm / % n=49 100% n=49 Canine Antigen Compared to necropsy verified samples. Lyme % n= % n=50 Canine Antibody Using validated ELISA reference method Ehrlichia % n= % n=214 Canine Antibody E. canis sensitivity 97.8%; n=45 E. chaffeensis sensitivity 95%; n=40 E. ewingii sensitivity 97.9%; n=47 Using E. canis/e. chaffeensis IFA titer reference method Anaplasma % n= % n=219 Canine Antibody A. phagocytophilum 92.6%; n=27 A. platys 93.9%; n=33 Agreement by any two: IFA, ELISA, or commercial kit FeLV/FIV / FeLV 96% n=93 FIV 99% n=114 FeLV 99% n=140 FIV 97% n=110 Feline Antigen/ Antibody Agreement by IFA and FeLV/FIV methodologies Parvo / % n= % n=258 Canine Antigen Compared to hemagglutination and PCR Giardia / % n= % n=243 Canine Antigen Compared to fecal wet mount and western blot cpl Data on file at Canine Pancreas- Specific Lipase Data on file at Data submitted to and approved by USDA. cpl does not require USDA licensing. 25
26 Lateral Flow Technology C T 26
27 Rapid Test Lateral Flow Technology Proven technology you can trust. For over 30 years, Lateral Flow technology has served as a reliable tool for efficient diagnosis and patient evaluation, improving the quality of care for human patients, and now, for our beloved pets. Antibody Lateral Flow Antigen Lateral Flow Magnification of the test T line The conjugate pad is pre-treated with specific colloidal gold-conjugated peptides and colloidal gold-conjugated signal amplification proteins. The membrane is pre-coated with antibody specific peptides that have been linked to a protein carrier at the Test T line. C T Magnification of the test T line Sample and specific colloidal gold-conjugated antibodies combine in the conjugate pad creating antigen-antibody-gold conjugate. The test is pre-coated with antigen-specific antibodies at the test T line. When the sample flows through the conjugate pad both colloidal gold conjugates bind to any specific antibodies present in the sample. C T The conjugates flow across the membrane and bind to the antibodies in the sample line forming a sandwich. When the gold labeled antibodies reach the test T line specific antibodies bind to the test T line forming an amplified sandwich complex which has been augmented by Abaxis patented signal amplification technology. The accumulation of the amplified sandwich complexes creates a visible signal. C T Positive Result The accumulation of sandwich complexes in the test T line creates a visible signal. Capture Antigen Carrier Protein Capture Antibody Generic Antigen Antibody of Interest Gold Nano Particle Gold Nano Particle Antigen of Interest Generic Antibody Signal Amplification Protein 27
28 Abaxis, Inc Whipple Road Union City, CA USA Tel Fax ABAXIS Europe GmbH Bunsenstr Griesheim Germany Tel Fax abaxis@abaxis.de GLOBAL DIAGNOSTICS The products disclosed in this brochure are intended for veterinary use only. Abaxis and VetScan are registered trademarks of Abaxis, Inc. Abaxis Rev. A
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