Chapter 2 - DNA MC [37 marks]
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1 Chapter 2 - N MC [37 marks] 1. The image shows a N nucleotide. Which correctly identifies the parts labelled I and II? C 2. Which model represents transcription?
2 3. Which sequence represents the order of events in protein synthesis? 4. What happens during glycolysis for one molecule of glucose?. Two pyruvates are formed.. There is a net gain of two NPH + H +. C. There is a net loss of two TP.. Two acetyl Co are formed. 5. Which type of bond is identified by the arrow?. Phosphate. Hydrogen C. Covalent. Peptide C 6. What is required to replicate N?. Temperature of 37 C. Free nucleotides carrying, C, G and T bases C. Plasmids. Endonuclease
3 7. How is the information in the genetic code used?. To predict the genotype of gametes. To distinguish prokaryotic genomes from eukaryotic genomes C. To deduce phenotypes in pedigree charts. To translate mrn into polypeptides 8. What is required to replicate N?. Temperature of 37 C. Free nucleotides carrying, C, G and T bases C. Plasmids. Endonuclease 9. The base sequence of a fragment of N is: CC GTG CG GT What is the base sequence on the messenger RN (mrn) molecule transcribed from it?. TGG CC GTC CT. TGG CUC GTC CTU C. UGG CTC GUC CUT. UGG CC GUC CU
4 What is correct for the N double helix? base substitution in a gene has changed a codon. Which of these consequences could result from a base substitution in a codon? I. nother amino acid will be incorporated in the protein II. stop codon is generated III. The same protein will be synthesized. I only. I and II only C. I and III only. I, II and III
5 What links the pairs of complementary bases in a N double helix? 12.. Covalent bonds. Hydrogen bonds C. Ionic bonds. Peptide bonds 13. Organisms can be genetically modified to produce the human blood clotting factor IX. What characteristic of the genetic code makes this possible?. It is conservative.. It is degenerate. C. It is complementary.. It is universal What is the relationship between enzymes and N? 14.. Enzymes contain the code for N.. Enzymes act on N during translation. C. oth enzymes and N have similar shapes.. The structure of enzymes is determined by N. What occurs during N replication? 15.. N polymerase separates the two N strands.. N molecules containing nucleotides from the original molecule are produced. C. denine forms a base pair with either thymine or uracil.. New bases attach to the original sugar-phosphate backbone.
6 The diagram shows the translation of a mrn molecule. 16. trn molecule with anticodon CG carries the amino acid phenylalanine. Which codon of mrn will the trn join?. CTG. CG C. GTC. GUC What is formed during transcription? 17.. RN strand complementary to N strand, formed by RN polymerase. N strand complementary to N strand, formed by N polymerase C. RN strand complementary to RN strand, formed by N polymerase. N strand complementary to RN strand, formed by RN polymerase What occurs during N replication? 18.. N polymerase separates the two N strands.. N molecules containing nucleotides from the original molecule are produced. C. denine forms a base pair with either thymine or uracil.. New bases attach to the original sugar-phosphate backbone.
7 Which of the following statements is/are correct for N replication? 19. I. It occurs during interphase. II. It is semi-conservative. III. It is a stage in protein synthesis.. I only. II only C. I and II only. I, II and III C Which of the following processes uses N ligase? 20.. Unwinding N. Gene transfer using plasmids C. dding primers. Complementary base pairing What does the structure labelled X represent? 21.. Hydrogen bond. Phosphate C. Covalent bond. ase C 22. What does the structure labelled Y represent?. Ribose. Thymine C. Guanine. eoxyribose Which points to the 3 end of a strand of N? 23.. I. II C. III. IV
8 What type of bond does Z represent? 24.. Covalent bond. Hydrogen bond C. Peptide bond. Semi-conservative bond The diagram shows part of a N molecule. 25. What type of bond does X represent?. Covalent bond. Hydrogen bond C. Peptide bond. Semi-conservative bond 26. What will be the sequence on the mrn molecule that is produced when the N base sequence CTGTGCC is transcribed?. CTGTGCC. CUGUGCC C. TGCTCGG. UGCUCGG Which of the following are involved in both replication and transcription? 27.. N only. N and RN C. N and ribosomes. N, RN and ribosomes What is a codon? 28.. sequence of nucleotides on rrn that corresponds to an amino acid. sequence of nucleotides on mrn that corresponds to an amino acid C. sequence of nucleotides on trn that corresponds to an amino acid. sequence of nucleotides on N that corresponds to an amino acid
9 What sequence of processes is carried out by the structure labelled X during translation? 29.. Combining with an amino acid and then binding to an anticodon. inding to an anticodon and then combining with an amino acid C. inding to a codon and then combining with an amino acid. Combining with an amino acid and then binding to a codon The following diagram shows a short stretch of N. What bases are indicated by labels Y and Z? 30.
10 Which molecules form the nucleotide marked in the diagram? 31.. phosphate, deoxyribose and nitrogenous base. phosphorus, ribose and nitrogenous base C. phosphorus, deoxyribose and guanosine. phosphate, ribose and guanine Which enzyme catalyzes the elongation of the leading strand? 32.. RN polymerase. Helicase C. N polymerase. Ligase C
11 33. The table below shows the codons that determine different amino acids in protein translation. What is the sequence of the amino acids that is being translated from the following mrn sequence?. Met-Pro-rg-Ile-Thr. Met-Cys-Ser-Tyr-Trp C. Met-Gly-la-Tyr-Trp. Met-Gly-Tyr-la-Thr 5' UGGGUGCUUUUGGU 3' C 34. What principle is necessary to prevent mutation of N during replication?. ase pairing is complementary.. One gene codes for one polypeptide. C. Substrates are specific to enzymes.. The genetic code is universal. 35. What happens during translation?. Copying of N to produce N. Copying of N to produce mrn C. Copying of N to produce trn. Polypeptide synthesis
12 In the model of the N molecule shown below, which arrows point to covalent bonds? 36.. I, II and III only. II, III and IV only C. I, III and IV only. I, II and IV only On which molecule is a codon found? 37.. N. mrn C. trn. rrn International accalaureate Organization 2017 International accalaureate - accalauréat International - achillerato Internacional Printed for Highland High School
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