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1 Intraocular Lens (IOL): Market Shares, Strategies, and Forecasts, Worldwide, Nanotechnology, 2013 to 2018 Intraocular Lens (IOL): Cataract Surgical Eye Implants, Visualization Technologies Improving Treatment Torrie The Cat in the Tulips Picture by Susan Eustis WinterGreen Research, Inc. Lexington, Massachusetts CHECK OUT THESE KEY TOPICS

2 Cataract Surgery Intraocular Lens (IOL) Hydrophilic Collamer Ultra- High Water Toric Visual Acuity FDA-Approved Intraocular Lens Medical Optics Cataract Cataract Surgical Eye Surgical Techniques IOL Acrylic Material Cataract Surgery Ocular Surgical Guidance Technology Femtosecond Technology Intraocular Lens (IOL) Market Share Intraocular Lens (IOL) Market Forecasts IOL Market Share IOL Market Forecasts Intraocular Lens (IOL): Technology Evolves Delivery of Improved Vision Intraocular Lens (IOL): Market Shares, Strategies, and Forecasts, Worldwide, LEXINGTON, Massachusetts (February 11, 2013) WinterGreen Research announces that it has published a new study Intraocular Lens (IOL) Market Shares, Strategy, and Forecasts, Worldwide, 2013 to The 2013 study has 293 pages, 67 tables and figures. Worldwide markets are poised to achieve continuing growth as the aging population worldwide develops cataracts and need Intraocular Lenses (IOL). All older people develop cataracts. Cataracts are a clouding of the eye's natural lens that impairs one's ability to see clearly. With two accommodating Intraocular Lens IOLs likely to be approved within the next 12 months, the premium market is again exciting. Intraocular lens market driving forces include the aging of the population. With age, all people have cataracts which can be cured with IOL. There is an ever-increasing baby boom aging population. There is a growing precision of cataract surgery. Safety of cataract surgical medical devices and lenses are primary market concerns. More advanced procedures are driving an increase in cataract surgery. Lower costs per surgery are driving an increase in cataract surgery. Cataract surgical technology is evolving rapidly. Premium intraocular lenses (IOLs) introduced during the past decade and those still in the pipeline are raising patient s post-cataract visual expectations. Laser-assisted cataract surgery technology is gaining traction with clinicians. Surgeons are getting trained in the techniques needed to perform surgeries these new types of equipment. The motivation to learn the new surgical techniques is that the equipment comes with the promise of improved surgical precision. According to Susan Eustis, lead author of the WinterGreen Research team that prepared the Intraocular Lens (IOL) market research study, Superior image quality brings clinical improvement. Patients are thrilled when they can see so much more clearly.

3 As a result, growing needs and expectations for good vision in all ranges have created significant new market opportunities, expanding demand for multifocal and accommodating IOLs designed to correct presbyopia, aspheric optics that address spherical aberration and make vision sharper, and phakic IOLs allowing treatment of extreme refractive error. Ultrasonic phacoemulsification, the standard of care in cataract removal equipment for four decades, has been in great part responsible for the safety and effectiveness of modern cataract surgery. It is certain to remain the dominant lens removal technology in the near term. A technology still in its infancy, laserassisted cataract surgery using femtosecond lasers and picosecond lasers, promises to raise the standard of precision and safety to new heights. Numerous types, and styles of Intraocular Lenses (IOLs), varying in size, and attachment mechanisms. The femtosecond lasers may evolve capability to fix the cataract without implanting an IOL devices, creating a significant change in the market after the forecast period. The eye care industry is highly competitive and subject to rapid technological change and evolving industry requirements and standards. Companies within this industry compete on technological leadership and innovation, quality and efficacy of their products, relationships with eye care professionals and healthcare providers, breadth and depth of product offering and pricing. The presence of these factors varies across regions. In the United States, the leading market segment, an aging population, the affluence of the American baby boomer generation, and the ability of surgeons to bill for a premium refractive outcome will drive significant growth in this lens-based refractive surgery sector. Intraocular Lens (IOL) markets are driven by the trend towards multi-distance vision capability, near middle, and far. The global market is expected to post a modest growth. The global market for Intraocular Lenses (IOL) total market value is expected to reach $3.8 billion by The global intraocular lens cataract market is expanding with the aging of a more affluent middle class population. There were 19 million cataract surgeries in 2010 and 19.7 million in Cataracts account for 48% of world blindness. Cataracts are the leading cause of reversible blindness. WinterGreen Research is an independent research organization funded by the sale of market research studies all over the world and by the implementation of ROI models that are used to calculate the total cost of ownership of equipment, services, and software. The company has 35 distributors worldwide, including Global Information Info Shop, Market Research.com, Research and Markets, electronics.ca, Bloomberg, and Thompson Financial. Key Words: Cataract Surgery, Intraocular Lens (IOL), Hydrophilic Collamer Ultra-High Water, Toric Visual Acuity, FDA-Approved Intraocular Lens, Medical Optics Cataract, Cataract Surgical, Eye Surgical Techniques, IOL Acrylic Material, Cataract Surgery, Ocular Surgical Guidance Technology, Femtosecond Technology, Intraocular Lens (IOL) Market Share, Intraocular Lens (IOL) Market Forecasts, IOL Market Share, IOL Market Forecasts,

4 Companies Profiled Market Leaders Novartis / Alcon Abbott Medical Optics Bausch & Lomb Hoya Carl Zeiss Meditec AG Staar Surgical EuroCrystal SA HumanOptics AG OPHTEC BV Market Participants Akkolens Allergan Aravind Biovision Elenza Kowa Company, Ltd. Lenstec Novartis Group / Alcon OptiMedica Physiol Rayner Staar Surgical WaveTec Vision Intraocular Lens (IOL): Market Shares, Strategies, and Forecasts, Worldwide, 2013 to 2018 Report Methodology This is the 546th report in a series of primary market research reports that provide forecasts in communications, telecommunications, the Internet, computer, software, telephone equipment, health equipment, and energy. Automated process and significant growth potential are priorities in topic selection. The project leaders take direct responsibility for writing and preparing each report. They have significant experience preparing industry studies. Forecasts are based on primary research and proprietary data bases.

5 The primary research is conducted by talking to customers, distributors and companies. The survey data is not enough to make accurate assessment of market size, so WinterGreen Research looks at the value of shipments and the average price to achieve market assessments. Our track record in achieving accuracy is unsurpassed in the industry. We are known for being able to develop accurate market shares and projections. This is our specialty. The analyst process is concentrated on getting good market numbers. This process involves looking at the markets from several different perspectives, including vendor shipments. The interview process is an essential aspect as well. We do have a lot of granular analysis of the different shipments by vendor in the study and addenda prepared after the study was published if that is appropriate. Forecasts reflect analysis of the market trends in the segment and related segments. Unit and dollar shipments are analyzed through consideration of dollar volume of each market participant in the segment. Installed base analysis and unit analysis is based on interviews and an information search. Market share analysis includes conversations with key customers of products, industry segment leaders, marketing directors, distributors, leading market participants, opinion leaders, and companies seeking to develop measurable market share. Over 200 in depth interviews are conducted for each report with a broad range of key participants and industry leaders in the market segment. We establish accurate market forecasts based on economic and market conditions as a base. Use input/output ratios, flow charts, and other economic methods to quantify data. Use in-house analysts who meet stringent quality standards. Interviewing key industry participants, experts and end-users is a central part of the study. Our research includes access to large proprietary databases. Literature search includes analysis of trade publications, government reports, and corporate literature. Findings and conclusions of this report are based on information gathered from industry sources, including manufacturers, distributors, partners, opinion leaders, and users. Interview data was combined with information gathered through an extensive review of internet and printed sources such as trade publications, trade associations, company literature, and online databases. The projections contained in this report are checked from top down and bottom up analysis to be sure there is congruence from that perspective. The base year for analysis and projection is With 2010 and several years prior to that as a baseline, market projections were developed for 2011 through These projections are based on a combination of a consensus among the opinion leader contacts interviewed combined with understanding of the key market drivers and their impact from a historical and analytical perspective.

6 The analytical methodologies used to generate the market estimates are based on penetration analyses, similar market analyses, and delta calculations to supplement independent and dependent variable analysis. All analyses are displaying selected descriptions of products and services. This research includes reference to an ROI model that is part of a series that provides IT systems financial planners access to information that supports analysis of all the numbers that impact management of a product launch or large and complex data center. The methodology used in the models relates to having a sophisticated analytical technique for understanding the impact of workload on processor consumption and cost. WinterGreen Research has looked at the metrics and independent research to develop assumptions that reflect the actual anticipated usage and cost of systems. Comparative analyses reflect the input of these values into models. The variables and assumptions provided in the market research study and the ROI models are based on extensive experience in providing research to large enterprise organizations and data centers. The ROI models have lists of servers from different manufacturers, Systems z models from IBM, and labor costs by category around the world. This information has been developed from WinterGreen research proprietary data bases constructed as a result of preparing market research studies that address the software, energy, healthcare, telecommunications, and hardware businesses. YOU MUST HAVE THIS STUDY Intraocular Lens (IOL):: Market Shares, Strategies, and Forecasts, Worldwide, Executive Summary Table of Contents The study is designed to give a comprehensive overview of the Intraocular Lens equipment market segment. Research represents a selection from the mountains of data available of the most relevant and cogent market materials, with selections made by the most senior analysts. Commentary on every aspect of the market from independent analysts creates an independent perspective in the evaluation of the market. In this manner the study presents a comprehensive overview of what is going on in this market, assisting managers with designing market strategy likely to succeed. INTRAOCULAR LENS (IOL) EXECUTIVE SUMMARY Intraocular Lens Market Driving Forces ES-1 ES-1

7 Cataract Surgical Technology Is Evolving Rapidly Patient Populations Have Significant Demand for Cataract Surgery Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved Cataract Surgery Business Intraocular Lens Market Challenges World Population Growth Intraocular Lens Market Shares Intraocular Lens Market Forecasts Intraocular LensMarket Description and Market Dynamics ES-3 ES-4 ES-5 ES-5 ES-6 ES-6 ES-7 ES-9 1. INTRAOCULAR LENS MARKET DESCRIPTION AND MARKET DYNAMICS Cataract Surgical Technology Is Evolving Rapidly Patient Populations Have Significant Demand for Cataract Surgery Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved Cataract Surgery Business Intraocular Lens Market Challenges World Economy Undergoing A Transformation Global Economic Conditions: Global Economy Becomes Steadily More Sluggish Global Economic Conditions Impact Markets 1-11 Intraocular LensMarket Shares and Market Forecasts This section selectively describes market shares, forecasts, segments, and regional revenue. Numbers are the result of primary research in all cases. Selected company are described from an independent analyst perspective with a thumbnail sketch or analysis of their market numbers or commentary on their strengths and weaknesses. Some of the analysis is focused on looking at the topic segment by segment, including company descriptive analyses by segment and subsegment. 2. INTRAOCULAR LENS MARKET SHARES AND FORECASTS Intraocular Lens Market Driving Forces Cataract Surgical Technology Is Evolving Rapidly Patient Populations Have Significant Demand for Cataract Surgery Challenge To Get Wide Acceptance Of A New Lens Once It Is Approved Cataract Surgery Business Intraocular Lens Market Challenges World Population Growth Intraocular Lens Market Shares Novartis / Alcon Novartis / Alcon Competitive Situation Novartis / Alcon Competition Novartis Alcon Multifocal Lenses Novartis / Alcon Novartis / Alcon Novartis / Alcon AcrySof Toric Intraocular Lens - (IOL) FDA Approval P930014/S LenSx Acquired by Alcon Abbott Medical Optics Abbott Medical Optics / Visiogen s Synchrony Abbott Tecnis Abbott TECNIS IOLs Bausch & Lomb Presbyopic IOLs 2-19

8 Bausch + Lomb Bausch + Lomb Eye Surgical Technologies In The Pipeline Bausch + Lomb: Accommodating IOLs Bausch + Lomb: Crystalens IOL OptiMedica Staar Acrylic IOL Staar Staar Silicone IOLs Staar Surgical Company nanoflex IOL Staar Visian LensAR PhysIOL's FineVision IOL Research and New Lenses ReSTOR Multifocal Toric AcrySof IQ Abbott Tecnis One-Piece Toric Lenstec Tetraflex Calhoun Vision Light-Adjustable Lens Abbott Visiogen Synchrony Rayner M-flex T NuLens DynaCurv Carl Zeiss AcriLisa Diffractive Multifocal Toric Bausch + Lomb s Crystalens Toric Hoya s Adoptics Intraocular Lens Market Forecasts Intraocular Lens Market Segment Forecasts Number of Cataract Surgeries Per Year Novartis Positioning with Sales and Marketing Resource Bausch + Lomb Small Incisions Femtosecond Technology Is Game Changer Intraocular Lens Unit Analysis Aspheric Foldable IOL Lens Intraocular Lens Presbyopia Market Forecasts Market Trend: Monofocal IOL Channel Will Be Slowly But Continuously Eroded By The Multifocal IOL Presbyopia-Correcting Intraocular Lens (IOL) Premium Channel Surgeons Market Trend: Accommodating IOL Channel to Grow Market Trends: Diffractive Lenses Market Trend: Multifocal IOLs Market Trend: Surgical Workstation Premium IOL Forecasts Technologies Driving Intraocular Lens IOL Market Growth Diffractive IOLs Large Middleclass Population Base Driving Intraocular Lens IOL Market Growth Nonfoldable Polymethylmethacrylate/Plexiglas Based Lenses To Silicone And Acrylic Based Foldable Lenses Global Vision Care and Ocular Market Intraocular Lens Prices Premium Lens Technology Reimbursement Trends CMS Medicare Intorocular Reimbursement Guidelines Intraocular Lens Regional Market Eye Surgical Techniques by Country United States Canada Brazil Cataract Surgical Procedure Brazilian Cataract surgeries China 2-68

9 2.5.7 Toric Lens Implantations On The Rise In Europe Advanced Technology Intraocular Lens Growth Markets Cataract Surgery in the UK Asia-Pacific Cataract Surgery Cataract Surgery in India Cataract Surgery Assembly Line System Followed At Aravind Eye Hospitals Aurolab s Low-Cost, High-Volume Business Model Highly Efficient Operations Coupled With Pricing Structure Allow 50% Profit Margin World Health Organization (WHO), 2-75 Intraocular Lens Product Description This section describes selected company and selected products. Products for this market segment are described with attention to the most significant aspect of features and functions in this category of product. The juxtaposition of a range of different product descriptions from a single market category provides a really good way to access market directions and achieve market competitive analysis. This section is arranged in three pieces: immersive products, conference room products, and end point products. Company products are described in the appropriate sections, meaning a company is mentioned several times in the chapter in different places INTRAOCULAR LENS (IOL) PRODUCT DESCRIPTION IOL lenses Novartis / Alcon Novartis / Alcon Novartis / Alcon Competitive Situation Novartis / Alcon Competition Novartis Alcon Multifocal Lenses Novartis / Alcon Novartis / Alcon Novartis / Alcon AcrySof Toric Intraocular Lens - (IOL) FDA Approval P930014/S LenSx Acquired by Alcon Abbott Medical Optics / Visiogen s Synchrony Abbott Medical Optics Synchrony Abbott Medical Optics Abbott Medical Optics / Visiogen s Synchrony Lens Bausch & Lomb / Crystalens Bausch & Lomb Crystalens AO Lens Bausch + Lomb: Accommodating IOLs Bausch + Lomb: Crystalens IOL Bausch & Lomb Crystalens HD Calhoun Vision s Light Adjustable Lens NuLens PixelOptics Imperial Medical Technologies Presbia s Flexivue Lenstec s Tetraflex Lens Staar STAAR Surgical Company nanoflex IOL Staar Elastimide Silicone Aspheric IOL Staar nanoflex Collamer Aspheric Single-Piece IOL Staar Afinity Collamer Aspheric IOL STAAR Toric IOL Staar Afinity and nanoflex Collamer Aspheric IOLs Staar Collamer Advantage Staar nanoflex Collamer Aspheric Single-Piece IOL 3-36

10 STAAR Surgical Elastimide Silicone Aspheric IOL Model AQ2015A STAAR Elastimide Lens Model AQ2003V STAAR Elastimide Lens Model AQ2010V STAAR Elastimide Lens Model AQ5010V - Low Diopter STAAR Elastimide Lens Model AQ2017V (Discontinued) STAAR Elastimide Lens Model AQ1016V (Discontinued) STAAR Elastic Lens Model AA4204VF STAAR Elastic Lens Model AA4204VL STAAR Elastic Lens Model AA4207VF (Discontinued) STAAR Toric Silicone Single Piece IOL STAAR Elastic Toric Lens Model AA4203TL Canon-STAAR Preloaded IOL Model KS-3Ai Lxenstec s Tetraflex Lxenstec s Tetraflex Manufactured To A Tenth Of A Diopter Toleranc3-e Lxenstec Elenza Lens Hoya Tecnis MF PowerVision (Belmont, Calif.), Oculentis (Berlin), and PhysIOL (Liège, Belgium PowerVision's FluidVision FluidVision MPlus by Oculentis PhysIOL's FineVision WaveTec Vision Pediatric Cataract / Intraocular Lenses (IOL) D change in power is needed between ages 10 and Correcting Astigmatism in Pediatric Patients 3-69 Intraocular Lens Technology 4. INTRAOCULAR LENS (IOL) TECHNOLOGY The Human Eye Cataracts Staar Collamer Cataract Symptoms Benefits Of Cataract Eye Surgery How Cataract Eye Surgery Is Performed Intraocular Tens Technology Technologies Driving Intraocular Lens IOL Market Growth Aspheric Contact Lenses Refractive Disorders Studies On The Restor Toric Lens MNRead Functional Reading Test Surgeons Need To Concentrate On Proper Patient Selection Mayo Clinic Study of Long-Term Dislocation Of Intraocular Lenses Obesity Cause of Diabetes and Neuropathy of the Eye 4-25 Intraocular Lens Company Profiles This section selectively describes company strategy, partners, acquisitions, and revenue by segment and regional revenue when available. Company are described by looking at what is most interesting about that company. The descriptions collectively give a sense of market directions within the industry segment. The alphabetical listing of company thumbnail sketches provides an accessible way to find out what is going on in any particular company.

11 5. INTRAOCULAR LENS (IOL) COMPANY DESCRIPTION Abbott Laboratories Abbott Acquired Visiogen with Synchrony Product Abbott Labs Cataract Company Acquisitions Abbott Completes Separation of Research-Based Pharmaceuticals Business Abbott (NYSE: ABT) Separation Of Its Research-Based Pharmaceuticals Business Abbott Separating Into Two Independent Companies Abbott Laboratories and Subsidiaries Revenue Abbott Sales Mix Abbott Nutritional Market Presence Abbott Diagnostics Market Presence Abbott Medical Devices Market Presence Abbott Strength Through Ability to Innovate Abbott Revenue Abbott Medical Optics Abbott Medical Optics Corneal Products Abbott Medical Optics Refractive Product Line Abbott Medical Optics Cataract Products Abbott Medical Optics Technological Innovation Akkolens AkkoLens Features AkkoLens Clinical Partners Allergan Allergan Flagship Franchises In Eye Care, Neurosciences, Medical Dermatology And Urologics Allergan Acquisition of Inamed Corporation Allergan Specialty Product Lines Focused On High-Growth Markets Allergan Global in reach. Specialized in focus Allergan Leading Products Allergan/ SkinMedica, Inc. Acquisition Allergan Obesity Intervention Aravind Future of Aravind Bausch And Lomb Bausch + Lomb Vision Care Bausch + Lomb Pharmaceuticals Bausch + Lomb Cataract and Vitreoretinal Surgery Bausch + Lomb to Acquire Technolas Perfect Vision GmbH Bausch + Lomb Technolas Perfect Vision Bausch + Lomb Technolas Perfect Vision Transforming Refractive Surgery Bausch + Lomb to Acquire Technolas Perfect Vision GmbH Technolas Perfect Vision Biovision Elenza Kowa Company, Ltd Environmental & Energy Saving Products Hoya Hoya, Seiko And Epson; Agreements Executed In The Field Of Optical Products Business Hoya Second Quarter Revenue Lenstec Novartis Group / Alcon Novartis Alcon Division Novartis Revenue Alcon Cataract Surgery Alcon Surgical Glaucoma Alcon Vitreoretinal Alcon Refractive Surgery Alcon Acquires Leading Ocular Surgical Guidance Technology 5-43

12 Alcon Alcon Acquired The Ophthalmic Division of SensoMotoric Instruments (SMI) Alcon Division Surgical Products Alcon Ophthalmic Pharmaceuticals Alcon Products Alcon Cataract Reimbursement Alcon Regulation LenSx Acquired by Alcon OptiMedica Catalys next generation laser cataract surgery platform Physiol Physiol Multifocal IOL FineVision (Micro F) Rayner Surgery on 109 Year old Woman Using Rayner IOL Staar Surgical STAAR Surgical Devices Used In Corrective Surgery STAAR Surgical Minimally Invasive Intraocular Lenses (IOLs) WaveTec Vision WaveTec Vision Secures $16.5m To Market Cataract Surgery System Zeiss Zeiss Vision Zeiss Revenue Selected Companies in the Market 5-70 Intraocular Lens Executive Summary List of Tables and Figures Table ES-1 ES-1 Intraocular Lens Market Driving Forces Figure ES-2 ES-2 Advanced Technology Intraocular Lens Growth Drivers Table ES-2 ES-4 Cataract Surgery Diverse Market Growth Drivers Several generations of IOLs have created significant technical advances in the market. Intraocular Lens market challenges are evolving in the context of this dramatic market shift. Table ES-3 ES-6 Intraocular Lens Market Challenges Table ES-4 ES-8 Intraocular Lens (IOL) Market Shares, Dollars, Worldwide, 2012 Figure ES-5 ES-9 Intraocular Lens (IOL) Market Forecasts, Dollars, Worldwide, Intraocular Lens Market Description and Market Dynamics Table Cataract Surgery Diverse Market Growth Drivers Table Intraocular Lens Market Challenges Intraocular Lens Market Shares and Market Forecasts

13 Table Intraocular Lens Market Driving Forces Figure Advanced Technology Intraocular Lens Growth Drivers Table Cataract Surgery Diverse Market Growth Drivers Several generations of IOLs have created significant technical advances in the market. Intraocular Lens market challenges are evolving in the context of this dramatic market shift Table Intraocular Lens Market Challenges Table Intraocular Lens (IOL) Market Shares, Dollars, Worldwide, 2012 Table Intraocular Lens (IOL) Market Shares, Dollars, Worldwide, 2012 Table Novartis Cataract Surgical Techniques Figure Novartis / Alcon Overview of Surgical Franchise Figure Alcon Key Intraocular Lenses (IOLs) Products Table Novartis / Alcon IOL Market Strategic Positioning Figure Bausch + Lomb Crystalens is an FDA-approved intraocular lens Table ReSTOR s Acrylic Material Helps Keep It From Rotating Postop Figure Abbott Tecnis Toric IOL Figure Lenstec Tetraflex Figure Abbott Visiogen Synchrony Figure NuLens DynaCurv Figure Intraocular Lens (IOL) Market Forecasts, Dollars, Worldwide, Table Intraocular Lens Market Forecasts Units and Dollars, Worldwide, Figure Low End Intraocular Lens (IOL) Market Shipments Forecasts Dollars, Worldwide, Figure Premium Intraocular Lens (IOL) Market Shipments Forecasts Dollars, Worldwide, Table Intraocular Lens (IOL) Market Forecasts Units and Dollars, Worldwide, Figure Intraocular Lens (IOL), Market Forecasts, Units, Worldwide, Figure Novartis Franchise Dedicated Resources Figure

14 Cataract Surgery Pathophysiology, Prevalence, and Surgical Techniques Table Intraocular Lens Description Table Intraocular Lens Advanced Technology Figure Novartis Commentary on Cataracts as Leading Cause of Reversible Blindness Figure Intraocular Lens (IOL) Regional Market Segments, Dollars, 2012 Table Intraocular Lens (IOL) Regional Market Revenue Segments, US and Worldwide, Dollars, Worldwide, Table Intraocular Lens (IOL) Regional Market Revenue Segments, US and Worldwide Percent, Worldwide, Figure Eye Surgical Techniques by Country Intraocular Lens Product Description Figure Novartis / Alcon Key Intraocular Lenses (IOLs) Products Table Novartis Cataract Surgical Techniques Figure Novartis / Alcon Overview of Surgical Franchise Table Novartis / Alcon IOL Market Strategic Positioning Table Abbott Medical Optics Cataract Products Table Abbott Medical Visiogen s Synchrony lens Advantages Table Abbott Medical Visiogen s Synchrony Lens Disadvantages Figure Bausch + Lomb Crystalens FDA-Approved Intraocular Lens Figure Bausch + Lomb: Crystalens IOL Features Figure STAAR Surgical Company nanoflex IOL Figure Staar Implantable Collamer Lens for Quality of Vision Table Staar IOL Products Figure Staar Toric Visual Acuity Figure Hoya Pre-Loaded IOL Delivery System isert Intraocular Lens Technology

15 Figure Human Eye Figure Staar nanoflex Figure Staar nanoflex Collamer has a built in Anti-Reflective Interface Figure Staar Hydrophilic Collamer Ultra-High Water Content Layer On Its Surface Minimizing The Difference In Refractive Index Figure Staar nanoflex Collamer Percentage of Light Reflectance Figure Staar nanoflex Collamer Single Piece IOL Figure Staar nanoflex Collamer Incision Size Figure Staar nanoflex Collamer Protective Layer Figure Staar Afinity 3-Piece Collamer Aspheric IOL Model CQ2015A Function Modulation Transfer Function (MTF) Analysis Table Cataract Symptoms Intraocular Lens Company Profiles Table AkkoLens Technological Features Table AkkoLens Medical Features Figure Hoya IOL plant in Singapore Figure Novartis / Alcon Positioning in Healthcare Figure Novartis Resource By Segment Figure Novartis Surgical Franchise

16 ABOUT THE COMPANY WinterGreen Research, research strategy relates to identifying market trends through reading and interviewing opinion leaders. By using analysis of published materials, interview material, private research, detailed research, social network materials, blogs, and electronic analytics, the market size, shares, and trends are identified. Analysis of the published materials and interviews permits WinterGreen Research senior analysts to learn a lot more about markets. Discovering, tracking, and thinking about market trends is a high priority at WinterGreen Research. As with all research, the value proposition for competitive analysis comes from intellectual input. WinterGreen Research, founded in 1985, provides strategic market assessments in telecommunications, communications equipment, health care, Software, Internet, Energy Generation, Energy Storage, Renewable energy, and advanced computer technology. Industry reports focus on opportunities that expand existing markets or develop major new markets. The reports access new product and service positioning strategies, new and evolving technologies, and technological impact on products, services, and markets. Innovation that drives markets is explored. Market shares are provided. Leading market participants are profiled, and their marketing strategies, acquisitions, and strategic alliances are discussed. The principals of WinterGreen Research have been involved in analysis and forecasting of international business opportunities in telecommunications and advanced computer technology markets for over 30 years. The studies provide primary analytical insight about the market participants. By publishing material relevant to the positioning of each company, readers can look at the basis for analysis. By providing descriptions of each major participant in the market, the reader is not dependent on analyst assumptions, the information backing the assumptions is provided, permitting readers to examine the basis for the conclusions. About The Principal Authors Ellen T. Curtiss, Technical Director, co-founder of WinterGreen Research, conducts strategic and market assessments in technology-based industries. Previously she was a member of the staff of Arthur D. Little, Inc., for 23 years, most recently as Vice President of Arthur D. Little Decision Resources, specializing in strategic planning and market development services. She is a graduate of Boston University and the Program for Management Development at Harvard Graduate School of Business Administration. She is the author of recent studies on worldwide telecommunications markets, the top ten internet equipment companies, the top ten contract manufacturing companies, and the Top Ten Telecommunications market analysis and forecasts. Susan Eustis, President, co-founder of WinterGreen Research, is a senior analyst. She has done research in communications, healthcare equipment, and computer markets and applications. She holds several patents in microcomputing and parallel processing. She has the original patents in electronic voting machines. She has new patent applications in format varying, mulitprocessing, and electronic voting. She is the author of recent studies of the Regional Bell Operating Companies' marketing strategies, Internet equipment, biometrics, a study of Internet Equipment,

17 Worldwide Telecommunications Equipment, Top Ten Telecommunications, Digital Loop Carrier, Web Hosting, Web Services, and Application Integration markets. Ms. Eustis is a graduate of Barnard College. ORDER FORM Return To: WinterGreen Research, Inc. 6 Raymond Street Lexington, MA USA Phone: (781) Fax: (781) (preferred) info@wintergreenresearch.com PLEASE ENTER MY ORDER FOR: Intraocular Lens (IOL): Market Shares, Strategies, and Forecasts, Worldwide, ALL REPORTS ARE AVAILABLE IN EITHER PRINT OR PDF- PDF PRINT ENCLOSED IS MY CHECK FOR $3,800 FOR SINGLE COPY, $7,600 FOR WEB SITE POSTING PLEASE BILL MY COMPANY USING P.O. NUMBER PLEASE CHARGE MY MASTERCARD/VISA/AMERICAN EXPRESS CARD NUMBER EXP. DATE If charging to a credit card use the shopping card order form on the Internet, fax, or call. NAME TITLE SIGNATURE COMPANY DIVISION ADDRESS

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