20bis, rue du chapitre ROQUEMAURE FRANCE Tel : Fax : Web :
|
|
|
- Solomon Walsh
- 6 years ago
- Views:
Transcription
1 20bis, rue du chapitre ROQUEMAURE FRANCE Tel : Fax : contact-info@celld.com Web :
2
3 MedImmune MedImmune founded 1988 Targets: infectious diseases plasma- derived recombinant 5 licensed products 3 infectious disease & transplantation medicine 2 oncology products 2000 Revenue: $540 million Growing >50% per year Frederick Manufacturing Center
4 Frederick Manufacturing Center Manufacturing Facility 90,000 sq. ft. Recombinant and Plasmaderived products Plasma Production Module 25,000 sq. ft. Centrifuge Technology (4) P18 Powerfuge systems Plasma Capacity 300, ,000 L/year
5 Fractionation Process Objectives cgmp Compliance Performance
6 Fractionation Process Objectives cgmp Compliance Sanitary design Validatable Process Cleaning Closed system processing Stringent EM standards Static Dynamic
7 Fractionation Process Objectives Performance Maintain process temperature Cost effective productivity Process yield Equivalent or Improved
8 Manufacturing Operations Objectives Reproducible product quality Consistent error-free processing (control) Higher level operators High tech workplace Minimize direct intervention Environment Energy savings Optimized facility investment Quickest time from application to license Reliable process and equipment
9 Manufacturing Operations Specifications Overcome Historical Limitations Automated, closed system operation Process including paste recovery Clean in place Data collection Ease of use Ambient-temperature temperature process environment High tech environment for operators Energy and facility cost savings (cold, clean room) Low noise (Operator safety/comfort) Reliability (performance/maintenance)
10 CARR Powerfuge P18 Systems 15,000 x G Temperature controlled Vacuum D-Limonene (-18( to -24 C) Automated Paste Harvest 32 Kg / P18 Discharge Automated CIP Zone cleaning 23 internal sprayballs/nozzles Integrated into central systems
11 Powerfuge Performance Temperature Control Flow Rates Product Recovery Cleanability Environmental Monitoring
12 Temperature Control Temperature measurements source tank centrifuge feed centrifuge effluent destination tank Lines to and from Powerfuge First: chilled process concentrations Final: d-limonene d traced lines Powerfuge Isolated internal, machine cooling Operates under vacuum
13 Temperature Control & Flow Rates Centrifugation Temperatures and Flow Rates Temperature ( 0 C) Cryoprecipitate (5-6 lpm) Fraction I (4-5 lpm) Fraction II+III (4-5 lpm) Fraction V (6-7 lpm) -8.0 Source Tank Centrifuge Inlet Centrifuge Outlet Destination Tank Location
14 Cryoprecipitate Recovery Prior Contract Sources MedImmune Process using Powerfuge Cryo Recovery (g ppt/l plasma) Total Cryo Recovered from 3,200 liter batch (Kg)
15 Fraction II & III Recovery Fraction II & III Recovery (g ppt/l plasma) Total Fraction II & III Recovered from 3,200 liter batch (Kg) Prior Contract Sources MedImmune Process using Powerfuge
16 Fraction V Recovery Prior Contract Sources MedImmune Process using Powerfuge Fraction V Recovery (g ppt/l plasma) Albumin concentration (g/l suspension) Albumin recovery (g Albumin / L plasma)
17 Powerfuge P18 Automatic CIP CIP Sprayballs and Wash Zones Upper bearing wash Swinglock wash Feed path wash Bowl case wash Paste discharge chute wash (CIP cap) Lower case wash Bowl/scraper wash
18 CIP Validation Studies Cleaning validation Cleanability Dirty hold studies Clean hold studies Final rinse and swab testing Composite results seven runs
19 CIP Validation Results Rinse samples Conductivity: Endotoxin: Bioburden: TOC: 1.7µS/cm <0.02 EU/mL 2 CFU/10 ml <0.2 PPM
20 21 Swab Test Locations = Swab Point
21 CIP Validation Studies and Results Swab samples (21 sites) for TOC: Readily Accessible Sites (11) 5.8 µg/25cm 2 Post-disassembly Sites (10) 6.6 µg/25cm 2 70% of all sites below limit of quantitation Dirty-hold: up to 16 hrs Clean-hold: up to 5 days
22 Airborne Environmental Monitoring Static and dynamic conditions Viable and non-viable particulates Measured daily and during open operations Meets Class 100,000 specifications Surfaces Static and dynamic conditions Measured daily and during open operations Meets recommended EU limits for a Grade D (Class 100,000) area Noise level: 80 dba at maximum speed
23 Environmental Monitoring Extraordinary regulatory focus Drive to closed systems Tight control when product is exposed
24 MedImmune Licensing Process Submitted application: March, 2000 Pre-approval inspection: June, 2000 License: December, 2000
25 Conclusions cgmp focus simplified licensure Closed systems Automated harvest Automated CIP Environmental monitoring Demonstrated product equivalence Achieved comparable or higher yield Cost effective facility Next step: Optimize
26 Plasma Fractionation using CARR Powerfuge Technology Rudy Vasquez
Novel Technologies in Plasma Fractionation. Dieter Fassnacht
Novel Technologies in Plasma Fractionation Dieter Fassnacht Agenda Grifols Overview Grifols Engineering Innovations in - Pooling - Fractionation - Filling Developing new technologies to provide innovative
Effluent Decontamination
Effluent Decontamination Thermal Systems BSL-1 to BSL-4 OUR EXPERTISE SERVING YOUR PROJECT MORE THAN SOLUTIONS... Batch or continuous... Located in Evian, France, ACTINI has over 60 years experience and
Cleaning Validation in a Biologics Facility Case Study. CBE Pty Ltd
Cleaning Validation in a Biologics Facility Case Study CBE Pty Ltd This training program is copyright to CBE Pty Ltd and may not be modified, reproduced, sold, loaned, hired or traded in any form without
a solution for reducing the
Outsourcing the precision cleaning, a solution for reducing the environmental impact Trade fair Hanover 2015 Heiko ZSCHIEDRICH Hanover April 15, 2015 Summary 1. Introduction and presentation of ECP 2.
Polaris VCD. Efficient and Effective WFI Solutions WATER TECHNOLOGIES
Polaris VCD Efficient and Effective WFI Solutions WATER TECHNOLOGIES Your WF The POL Quantity and quality of water Standard units available between 50-15,000 l/hr High decontamination efficiency 3 stage
Cleaning Procedures. These guidelines are intended for Bulk Pharmaceutical Chemicals but almost every word applies to Drug Products
CLEANING DEVELOPMENT Cleaning Procedures as the FDA See It These guidelines are intended for Bulk Pharmaceutical Chemicals but almost every word applies to Drug Products BPC CLEANING (& Drug Products)
Purified Water Systems
TM Purified Water Systems TM Purified Water Systems A choice of quality Telstar-Puretech introduce the Oasys, opening a new chapter in pure water delivery. Telstar-Puretech Oasys Purified water systems
ARIA FLUID BED PROCESSOR
ARIA FLUID BED PROCESSOR ARIA Precise parameter control and premium quality engineering are the key features of IMA Active division s fluid bed processor. Simplified processing concepts based on smart
Cleaning Validation for Aseptic Manufacturing Equipment
Cleaning Validation for Aseptic Manufacturing Equipment Michelle Monk, Engineer Rizwan Sharnez, Ph.D., Scientific Director Amgen Advances in Aseptic Processing March 10-12, 2014 San Diego, CA Overview
PRIMARY GRADE WATER. PURELAB Prima. Primary Grade Water Purification Systems. The Laboratory Water Specialists
PRIMARY GRADE WATER PURELAB Prima Primary Grade Water Purification Systems The Laboratory Water Specialists PURELAB Prima The simple and dependable choice for primary grade water The PURELAB Prima range
Simplicity is the key Continuous purification of monoclonal antibodies
Simplicity is the key Continuous purification of monoclonal antibodies L. Landric-Burtin Head of Downstream Processing Development, France Integrated Continuous Biomanufacturing Conference, Barcelona,
Powerfuge for liquid/solid separations. CARR Powerfuge Pilot. Bridging the gap between bottles and continuous flow.
Powerfuge for liquid/solid separations CARR Powerfuge Pilot Bridging the gap between bottles and continuous flow. CARR Powerfuge Pilot BRIDGING THE GAP BETWEEN BOTTLES AND CONTINUOUS FLOW There s a point
Using the Sartobind pico
Using the Sartobind pico Optimizing Steps for using micro-scale membrane adsorbers on liquid chromatography systems Application Note Steps for the successful use of Sartobind pico 1. Start with a new unused
Technical Specification Industrial Series - IS2 to IS48 Systems. CapDI Benefits. Feed Water Quality. Design and Scope of Supply.
Technical Specification Industrial Series - IS2 to IS48 Systems Voltea s Industrial Series IS systems employ a simple, cost effective modular design providing flexibility to align with both current and
Amazon FILTRATION SOLUTIONS PHARMACEUTICAL MANUFACTURING
Amazon FILTRATION SOLUTIONS PHARMACEUTICAL MANUFACTURING FILTRATION SOLUTIONS FOR PHARMACEUTICAL MANUFACTURING Delivering quality filtration products As one of Europe s leading manufacturers of process
Performance Evaluation and Cleanability Study using Pellicon 3 Cassettes with 30 kd Biomax and Ultracel Ultrafiltration Membranes
Application Note Performance Evaluation Cleanability Study using Pellicon Cassettes with kd Biomax Ultracel Ultrafiltration Membranes Consistent, high performance ultrafiltration throughout multiple process
adrona Crystal E series Crystal E Ultrapure Crystal E HPLC Crystal E Bio Crystal E Pure Water purification systems
series adrona Water purification systems HPLC Bio Pure Features The highest water quality Perfect water quality guaranteed by two sensors directly at the Grade I dispense point and at the entrance of the
Microbiological Cleaning Method Validation
Microbiological Cleaning Method Validation The purpose of cleaning procedures should never be to reduce bioburden to an acceptable level! Fergus O Connell QA Manager Eurofins ams Laboratories www.eurofins.com
PURELAB CHORUS SYSTEMS
REACTION TANKS PURELAB CHORUS SYSTEMS SOLUTIONS FOR TYPE II PURE WATER AND TYPE III GENERAL GRADE WATER CONFIGURE YOUR SOLUTION STEP 1: CHOOSE YOUR SYSTEM INTEGRATED PURIFICATION TECHNOLOGY Typical Applications
Sullair Water Chillers. Precision Chilled Water
Sullair Water Chillers Precision Chilled Water Sullair Water Chillers What are Water Chillers? Why Choose a Sullair Water Chiller? Water chillers are used for controlled cooling of products, mechanisms
CENTRIFUGAL SEPARATORS FOR INDUSTRIAL APPLICATIONS
CENTRIFUGAL SEPARATORS FOR INDUSTRIAL APPLICATIONS The centrifugal force effective, reliable and innovative Over the years our group has developed a great experience and a strong know-how in the most important
Validation of Sterilizing Grade Filters
Validation of Sterilizing Grade Filters Presented by Laura Okhio-Seaman Sartorius Corporation 1 Sterilizing Grade Filters The definition of a sterilizing grade filter is one that will produce a sterile
The Opta SFT-D is available as individual device for end-user assembly with TPE tubing and autoclave sterilization.
Fluid Management 259 Connections 260 Flexboy Bags 264 Flexel 3D Bags 276 Palletank 304 Instruments 314 Single-Use Mixing 318 Freeze-Thaw Systems 354 Aseptic Transfer System 380 Configurable Solutions FlexAct
Multi-column Continuous Capture Chromatography New data confirming significant savings and de-bottlenecking opportunities
Multi-column Continuous Capture Chromatography New data confirming significant savings and de-bottlenecking opportunities Dr.-Ing. Kathleen Mihlbachler, LEWA Bioprocess Repligen Seminar: Advances in Bioprocessing,
Proudly serving laboratories worldwide since 1979 CALL for Refurbished & Certified Lab Equipment Parker N2-04
www.ietltd.com Proudly serving laboratories worldwide since 1979 CALL +847.913.0777 for Refurbished & Certified Lab Equipment Parker N2-04 The Parker Balston ELSD (Evaporative Light Scattering Detector)
Reflux Samplers for Process Gas Chromatographs Their Use and The Importance of Product Design
Yokogawa Corporation of America In today s industrial process world there is an on-going and overall reduction in the reliance in the use of manual monitoring and control and an increasing use of automation.
CASE HISTORY Presented by: Frank A. Richerand April 22, 2009
CASE HISTORY Presented by: Frank A. Richerand April 22, 2009 Produced Water Handling Gulf of Mexico Major Oil Company Process Repair & Bypass 17327 NORWEL DRIVE, COVINGTON, LA 70435 TEL: (985) 809-6480
COMPLIANCE WITH EU ANNEX 15: VALIDATION AND QUALIFICATION
COMPLIANCE WITH EU ANNEX 15: VALIDATION AND QUALIFICATION Paul L. Pluta, PhD Journal of Validation Technology Journal of GXP Compliance University of Illinois at Chicago (UIC) College of Pharmacy, Chicago,
Pollution Control BH-BL. BioDisc. High Performance Package Sewage Treatment Plants for Residential, Business & Leisure Applications. klargester.
Pollution Control BioDisc BH-BL High Performance Package Sewage Treatment Plants for Residential, Business & Leisure Applications klargester.com BioDisc BH-BL High Performance Package Treatment Plants
Dow Water Solutions. FILMTEC Membranes. Product Information Catalog
Dow Water Solutions Product Information Catalog For more information contact: info@lenntech.com www.lenntech.com Tel. +31-15-2610900 Fax. +31-15-261 Form No. 609-00204-1108 1. Product Overview 2. Tapwater
MICROBIOLOGY AND NEW TECHNOLOGY HOW TECHNOLOGY CAN IMPACT ON MICROBIOLOGICAL CONTROL
MICROBIOLOGY AND NEW TECHNOLOGY HOW TECHNOLOGY CAN IMPACT ON MICROBIOLOGICAL CONTROL DISCUSSION AREAS HOW MICROBIOLOGY NEEDS TO CHANGE TO MEET FUTURE DEMANDS AND PRODUCTION SYSTEMS MICROBIOLOGY AND PAT
Equipment Design Consideration for Cleaning & Cleaning Validation
Equipment Design Consideration for Cleaning & Cleaning Validation Gamal Amer, Ph. D. Principal Premier Compliance Services, Inc. All rights reserved. Do not copy without permission. 1 Cleaning and Cleaning
Filtration of Cell Culture Growth Media and Process Buffers
Customer Application Brief Bioprocess, Biologicals, & Pharmaceutical Filtration of Cell Culture Growth Media and Process Buffers Introduction Media feeds and process buffers are two universal additives
MicroCap Depth Filter Capsules. Uniquely Flexible to Meet Your Processing Needs
MicroCap Depth Filter Capsules Uniquely Flexible to Meet Your Processing Needs Efficient, Cost-Effective Batch Processing A Capsule Suite Customized to Fit Your Processing Needs Eliminate Batch Pooling
Review Validation of aseptic processes for pharmaceuticals
OPEM www.opem.org Oriental Pharmacy and Experimental Medicine 2010 10(4), 231-238 DOI 10.3742/OPEM.2010.10.4.231 Review Validation of aseptic processes for pharmaceuticals Lincy Joseph*, Mathew George
MERmaid Kit preps preps Filters/Catch Tubes Filters/Catch Tubes Filters/Catch Tubes
BIO 101 Protocol MERmaid Kit w eb With Optional SPIN Procedure Protocol Included Catalog Number Prep Size 1005-000 10 preps 1005-200 200 preps Optional 2080-400 40 Filters/Catch Tubes 2080-600 60 Filters/Catch
Standard Scalable Flexel 3D Bioprocessing Bags
Standard Scalable Flexel 3D Bioprocessing Bags Fluid Management Systems Description Standard Scalable Flexel 3D Bioprocessing Bags are designed for processing and storage of small volume biopharmaceutical
air classification UCX air classifier series
UCX air classifier series The process of air classification is of critical importance for many grinding operations. Generally the overall energy consumption for grinding can be reduced drastically provided
Human Protein Process Sciences, Lille, France 2. Shabrawishi Hospital Blood Bank, Cairo, Egypt 3. University of Saskatoon, Canada
1 Human Protein Process Sciences, Lille, France 2 Shabrawishi Hospital Blood Bank, Cairo, Egypt 3 University of Saskatoon, Canada Why such a concept? Non-virally inactivated plasma components are still
Use of Fluidised bed chromatography for plasma fractionation. Karl McCann*, John Wu, Peter Gomme & Joseph Bertolini
Use of Fluidised bed chromatography for plasma fractionation Karl McCann*, John Wu, Peter Gomme & Joseph Bertolini Plasma Fractionation Industry Mature with well established processes Revenue growth -
Introduction to TFF. Sengyong Lee Ph.D. Professor/ Program Chair Biotechnology/ Biology Ivy Tech Community College Bloomington, Indiana
Introduction to TFF Sengyong Lee Ph.D. Professor/ Program Chair Biotechnology/ Biology Ivy Tech Community College Bloomington, Indiana Main Agenda Biomanufacturing and Filtration Filtration Principles
DECANTER CENTRIFUGES FOR INDUSTRIAL APPLICATIONS
DECANTER CENTRIFUGES FOR INDUSTRIAL APPLICATIONS D E D I C A T E D I N N O V A T O R S The centrifugal force effective, reliable and innovative Over the years our group has developed a great experience
BSA FRACTION V BOVINE SERUM ALBUMIN
BSA FRACTION V BOVINE SERUM ALBUMIN BOVINE SERUM ALBUMIN PROLIANT BSA Proliant is the world s largest and most experienced manufacturer of animal-derived proteins, producing a variety of grades of Fraction
Sum Parameter Analysis AOX/TOX. AOX Analyzer multi X 2500
Sum Parameter Analysis AOX/TOX AOX Analyzer multi X 2500 > 2 multi X 2500 multi X a generation of AOX analyzers that is setting standards flexible, reliable, easy to operate, and capable of much more than
AIR QUALITY IN SWINE-FINISHING BARNS 1
Swine Day 2000 Contents AIR QUALITY IN SWINE-FINISHING BARNS 1 B. Z. Predicala 2, R. G. Maghirang 2, R.D. Goodband, S. B. Jerez 2, and J.E. Urban 3 Summary Air quality was assessed in two commercial swine-finishing
arium mini Ultrapure Water System
arium mini Ultrapure Water System Unique bagtank technology for the Highest Efficiency Advantages Reliable: Delivers consistently high water quality for reliable and reproducible results Efficient: Avoids
LiquidBiopsy LIQUIDBIOPSY. Automated Rare Template Isolation Platform
LiquidBiopsy LIQUIDBIOPSY Automated Rare Template Isolation Platform Enabling cancer research with highly multiplexed molecular analysis of serially collected blood samples The LiquidBiopsy Platform simplifies
PINCH ANALYSIS: For the Efficient Use of Energy, Water & Hydrogen. PULP AND PAPER INDUSTRY Energy Recovery and Effluent Cooling at a TMP Plant
PINCH ANALYSIS: For the Efficient Use of Energy, Water & Hydrogen PULP AND PAPER INDUSTRY Energy Recovery and Effluent Cooling at a TMP Plant PINCH ANALYSIS: For the Efficient Use of Energy, Water & Hydrogen
JONIX MATE NON THERMAL PLASMA TECHNOLOGY
Food Technology JONIX MATE NON THERMAL PLASMA TECHNOLOGY MOBILE MEDICAL DEVICE FOR INDOOR AIR PURIFICATION AND DECONTAMINATION MADE IN ITALY TECNOLOGIA JONIX uses the advanced oxidation process to decontaminate
Scaling Down Bioreactor Process Development: Comparison of Microbioreactor and Bench Scale Solutions.
Scaling Down Bioreactor Process Development: Comparison of Microbioreactor and Bench Scale Solutions. Richard Lugg. Scientist I, MedImmune. European Laboratory Robotics Interest Group: High Throughput
SMART PWD ASEPTIC POWDER FILLING AND STOPPERING MACHINE
SMART PWD ASEPTIC POWDER FILLING AND STOPPERING MACHINE SMART PWD ASEPTIC POWDER FILLING & STOPPERING MACHINE THANKS TO INTELLIGENT SERVO TECHNOLOGY, THE MACHINE IS EXTREMELY USER-FRIENDLY AND FLEXIBLE
AP-25 Plasma System AP-25 PLASMA THERMAL SPRAY SYSTEM
AP-25 PLASMA THERMAL SPRAY SYSTEM AP-25 Plasma System We set ourselves the challenge of producing a simple yet flexible, high tech system our customers can rely on. The result is the new 25-Series equipment
arium mini Ultrapure Water System
arium mini Ultrapure Water System Unique bagtank technology for the Highest Efficiency Advantages Reliable: Delivers consistently high water quality for reliable and reproducible results Efficient: Avoids
G.F. S.p.A. Via T. Edison, Rubbiano fraz. Solignano (PR) - Italy Tel Fax Web:
G.F. S.p.A. ia T. Edison, 3 43045 Rubbiano fraz. Solignano (PR) - Italy Tel. +39. 0525. 300311 Fax +39. 0525. 300350 Web: www.gfe.it E-mail: gfe@gfe.it Developed to process ampoules, vials and cartridges
Chlorine Scrubbing: Conversion from Batch to Continuous. Brent Hardman, P.E. Powell Fabrication & Mfg., Inc.
Chlorine Scrubbing: Conversion from Batch to Continuous Brent Hardman, P.E. Powell Fabrication & Mfg., Inc. Powell Fabrication & Mfg., Inc. Since 1964 Sodium Hypochlorite production, Chlorine Scrubbing
Preliminary Design of ITER Component Cooling Water System and Heat Rejection System
Preliminary Design of ITER Component Cooling Water System and Heat Rejection System A.G.A. Kumar 1, D.K. Gupta 1, N. Patel 1, G. Gohil 1, H. Patel 1, J. Dangi 1, L. Sharma 1, M. Jadhav 1, L. Teodoros 2,
Pioneering ALD experience since The ALD Powerhouse PRODUCT CATALOGUE FOR SUNALE P-SERIES ALD SYSTEMS
Pioneering ALD experience since 1974 The ALD Powerhouse PRODUCT CATALOGUE FOR SUNALE P-SERIES ALD SYSTEMS SUNALE P-SERIES ALD SYSTEMS PRODUCT CATALOGUE Description SUNALE P-series ALD system SUNALE P-series
Bioreactor System ERT 314. Sidang /2011
Bioreactor System ERT 314 Sidang 1 2010/2011 Chapter 2:Types of Bioreactors Week 2 Choosing the Cultivation Method The Choice of Bioreactor Affects Many Aspects of Bioprocessing. Product concentration
UltraClean Midi Plasmid Prep Kit
UltraClean Midi Plasmid Prep Kit Catalog No. Quantity 12700-20 20 Preps Instruction Manual Please recycle Version: 05232014 1 Table of Contents Introduction... 3 Protocol Overview... 3 Flow Chart... 4
Lenntech. Tel Fax
Lenntech info@lenntech.com Tel. +31-152-610-900 www.lenntech.com Fax. +31-152-616-289 Electrodeionization or EDI, is a continuous and chemicalfree process of removing ionized and ionizable species from
Tom Sulpizio and Jeff Taniguchi, Advanced Minerals Corporation A Member of Imerys 130 Castilian Way, Santa Barbara, CA 93117
ADVANCES IN DISPOSABLE DIATOMITE FILTER AID SYSTEMS FOR CGMP BIOSEPARATIONS Session Pretreatment in Bioseparations AFSS Annual Meeting Valley Forge, PA May 20, 2008 ABSTRACT Tom Sulpizio and Jeff Taniguchi,
A family of G. Alfa Laval s complete series of fuel ethanol decanters
A family of G Alfa Laval s complete series of fuel ethanol decanters Answering the global call for ethanol Alfa Laval s complete series of dedicated fuel ethanol decanters are unparalleled in performance,
Laboklav. Type 55 to 195 Liter. Technical Datasheet. Dampfsterilisatoren Steam sterilizers
Laboklav Dampfsterilisatoren Steam sterilizers Type 55 to 195 Liter Technical Datasheet Edition 07/2008 SHP Steriltechnik AG Gustav-Ricker-Str. 62 D-39120 Magdeburg Tel: +49 (0) 391 626988-0 Fax: +49 (0)
Cryogenic Metal Seated Butterfly Valves
Cryogenic Metal Seated Butterfly Valves The Key to Cryogenic Valve Solutions VELAN S.A.S VELAN Inc Group VELAN inc is one of the world's leading independent manufacturer of steel gate, globe, check, butterfly
BHS-FILTRATION INC. BHS VACUUM BELT FILTER, CANDLE & PRESSURE PLATE FILTER TECHNOLOGIES FOR BIO-ENERGY APPLICATIONS
BHS-FILTRATION INC. BHS VACUUM BELT FILTER, CANDLE & PRESSURE PLATE FILTER TECHNOLOGIES FOR BIO-ENERGY APPLICATIONS 1. Crop Feedstocks for Bio-Ethanol 2. Cellulose Feedstocks for Bio-Ethanol 3. Wood Feedstocks
2015 AQ Summit: Research Update by Peter Van Walsum
The University of Maine DigitalCommons@UMaine Annual Maine Aquaculture R&D and Education Summits Conferences and Summits 1-14-2015 2015 AQ Summit: Research Update by Peter Van Walsum Peter Van Walsum Follow
NutriStem V9 XF Medium
Stem Cells NutriStem V9 XF Medium A defined, xeno-free (XF), serum-free (SF) culture medium for hpsc using vitronectin Instructions for Use Product Description NutriStem V9 XF medium is a defined, xeno-free,
The evolution of high purity water production
FEDI Fractional Electrodeionization from EDI to FEDI The evolution of high purity water production EDI THE CONVENTIOL PROCESS Reject Electrodeionization Cell DEIONIZED WATER Reject Electrodeionization
TECHNICAL AND REGULATORY CONSIDERATIONS FOR PHARMACEUTICAL PRODUCT LIFECYCLE MANAGEMENT Q12
INTERNATIONAL CONCIL FOR HARMONISATION OF TECHNICAL REQUIREMENTS FOR PHARMACEUTICALS FOR HUMAN USE TECHNICAL AND REGULATORY CONSIDERATIONS FOR PHARMACEUTICAL PRODUCT LIFECYCLE MANAGEMENT Q12 ANNEX Draft
ISO INTERNATIONAL STANDARD
INTERNATIONAL STANDARD ISO 3826-3 First edition 2006-09-15 Plastics collapsible containers for human blood and blood components Part 3: Blood bag systems with integrated features Poches en plastique souple
SOLUBLE SALT METER SETTING THE NEW STANDARD IN SALT MEASUREMENT. Phone Phone: +31 (0) Fax: +31 (0)
SOLUBLE SALT METER SETTING THE NEW STANDARD IN SALT MEASUREMENT HedoN Electronic Developments Visitors & Correspondence Delftech Park - Elektronicaweg 15 2628 XG Delft - The Netherlands Phone Phone: +31
When Safety Comes First. Emergency Safety Shower and Eye Wash Catalogue
When Safety Comes First Emergency Safety Shower and Eye Wash Catalogue No industry, irrespective of its size or its function, can afford to neglect the safety of its personnel and the general public. Advances
The Culligan Hi-Flo 50 Series Industrial Water Filter System
The Culligan Hi-Flo 50 Series Industrial Water Filter System Durable High-Volume Water Filtration for Industrial Applications The Culligan Hi-Flo 50 Filter reduces contaminants* and solids that affect
Water Quality Specification for Power Supplies
Technical Note #6 Water Quality Specification for Power Supplies Introduction The cooling water for Alpha Scientific Power Supplies must meet certain minimum specifications in regard to quality and flow
one stop shop custom built solutions filtration & packaging Consulting New equipment Service & spare parts Reconditioning Go to main menu
one stop shop custom built solutions filtration & packaging Consulting New equipment Service & spare parts Reconditioning Go to main menu Select your presentation of interest below Filtration See Custom
35 STATION DOUBLE ROTORY COMPRESSION MACHINE
Page 1 of 16 User Requirement Specifications 35 STATION DOUBLE ROTORY Equipment ID: T-35COMP 01 Page 2 of 16 Table of Contents 1.0 APPROVAL SIGNATURES 2.0 OVERVIEW 3.0 PROCESS DESCRIPTION 4.0 PRODUCTIVITY
L A B W A T E R ULTRA-PURE WATER. PURELAB Ultra. Ultra-Pure Water Polishing System. The Laboratory Water Specialists
ULTRA-PURE WATER L A B W A T E R PURELAB Ultra Ultra-Pure Water Polishing System The Laboratory Water Specialists PURELABultra The PURELAB Ultra The new PURELAB Ultra is the state of the art ultra-pure
Energy Optimized Resource Recovery Project Presented By: Curtis Czarnecki, P.E.
Kenosha Wastewater Treatment Plant Energy Optimized Resource Recovery Project Presented By: Curtis Czarnecki, P.E. Kenosha Water Utility March 22, 2016 WWTP Service Area Overview Population: 110,000 Service
RiOs 3, 5, 8 Water Purification Systems
RiOs 3, 5, 8 Water Purification Systems Reliable and affordable pure water solutions Merck Millipore is a division of Reliable and affordable pure water solutions Your water purification needs Reliable,
3. Close the bottom end of the column and apply the packing device on top. Pump water through the upper adaptor to remove air.
INSTRUCTIONS FOR USE WorkBeads Protein A Product name Pack size Article number WorkBeads Protein A Bulk Media 1.5 ml 40605001 Bulk Media 5 ml 40605002 Bulk Media 10 ml 40605003 Bulk Media 100 ml 40605004
ATS WMK AGA. Installation and Operating Instructions ASI25 ISSUE D 15/02/2016
ATS 5200.477 WMK 60075 AGA www.acquasaver.com.au 1 Introduction The AcquaSaver valve is a fully automatic mechanical rainwater/mains water changeover device designed for pressure pump supply systems for
Parenteral Formulation Compounding
Parenteral Formulation Compounding Your partner in process technology Parenteral, Formulation, Compounding tailored to your needs What do we want out of each of our project? Do we want a project that has
The Elite Provider. Cell & Gene. Therapy Manufacturing
The Elite Provider Cell & Gene Therapy Manufacturing GMP Manufacturing Services The cgmp manufacturing in Vigene is compliant with US FDA and EU EMA regulatory requirements. The manufacturing area consists
Extending the Service Life of Anti-browning Solutions in Fresh-cut Fruit Processing
Customer Application Brief Extending the Service Life of Anti-browning Solutions in Fresh-cut Fruit Processing Introduction Food and Beverage Consumer demand for fresh-cut fruits and vegetables has grown
Cleaning Validation: A Timely Solution for Improving Quality and Containing Cost
: A Timely Solution for Improving Quality and Containing Cost by Christopher Crone This article presents an economic case for the use of on-line Total Organic Carbon (TOC) and conductivity analysis for
Direct Water purification system Pure & ultrapure water directly from tap water
Milli-Q Direct Water purification system Pure & ultrapure water directly from tap water ADVANCING LIFE SCIENCE TOGETHER Research. Development. Production. 1 Pure & ultrapure water from a single water system
Best Practices for a Robust Cleaning Validation
Best Practices for a Robust Cleaning Validation Beth Kroeger Technical Services Specialist STERIS Life Sciences & Amanda Deal Senior Technical Services Associate STERIS Life Sciences 1/ Agenda Variables
HL Pharm Tech Capsule Filling Machine HLF Series
EBSEOS GmbH Pharmaceutical Machinery & Services Industriestrasse 12 79664 Wehr Tel. ++49 (0)7762 80 68 966 Fax. ++49 (0)7762 80 68 967 HL Pharm Tech Capsule Filling Machine HLF Series The HL Pharm Tech
UltraPure Water Application Culture of Nerve Cells
UltraPure Water Application Culture of Nerve Cells Authors : * Dr Shinichi KOHSAKA Division of Neurochemistry National Institute of Neuroscience National Center of Neurology and Psychiatry, Tokyo, JAPAN
high efficiency ~ simple package ~ proven reliability ChromaPur Chromic Acid Purification Unit
high efficiency ~ simple package ~ proven reliability ChromaPur Chromic Acid Purification Unit Achieve maximum recovery, maximum cost reduction, and maximum quality consistency with Eco-Tec s chromic acid
The Ultimate Pasta Press
The Ultimate Pasta Press 2 Demaco Simplicity The Ultimate Pasta Press The Ultimate Pasta Press The press of the Pastaio (master pasta maker), designed for endurance and ease of operation. DEMACO machines
The waste water industry relies purely on performance
www.howden.com The waste water industry relies purely on performance Aeration technology and control systems for waste water plants In an industry where performance and reliability are essential, Howden
Innovative technology and products for consumer goods industry
Innovative technology and products for consumer goods industry Your automation partner for the consumer goods industry Food production Beverages production Home and personal care production Tissue and
Powder Processing Equipment - General Catalog
Powder Processing Equipment - General Catalog Nisshin Engineering provides solutions for global needs through powder technology NISSHIN ENGINEERING INC. HEADQUARTERS 14-1 Koami-cho, Nihonbashi, Chuo-ku,
YOUR DIRTY PROCESS WATER IS INCREASING YOUR TOTAL OPERATING COSTS
YOUR DIRTY PROCESS WATER IS INCREASING YOUR TOTAL OPERATING COSTS Presented by Vortisand Water Expert Mike Ditton 2017 Evoqua Water Technologies LLC MIKE DITTON WATER FILTRATION EXPERT Mike Ditton Water
OPUS 5, cm Columns OPUS 45R, OPUS 60R Columns REGULATORY SUPPORT FILE
OPUS 5, 10-60 cm Columns OPUS 45R, OPUS 60R Columns REGULATORY SUPPORT FILE The information contained in this document is subject to change without notice. Repligen Corporation makes no warranty of any
OPERATING PARAMETERS Reliable Means to Continuously Monitor Facility Performance
OPERATING PARAMETERS Reliable Means to Continuously Monitor Facility Performance RICHARD SCHERRER Ogden Martin Systems, Inc. Fairfield, New Jersey ABSTRACT Energy sales are a major source of revenues for
COACH INTERIORS VACUUM TOILET SYSTEM
COACH INTERIORS VACUUM TOILET SYSTEM DESIGN MANUFACTURE INSTALLATION SERVICING ABOUT US We are a proud Indian Company; our strength and pride comes from our people, our technology, cost effective customization