Author s response to reviews

Transcription

1 Author s response to reviews Title: Assessment of laparoscopic stomach preserving surgery with sentinel basin dissection versus standard gastrectomy with lymphadenectomy in early gastric cancer-a multicenter randomized phase III clinical trial (SENORITA trial) protocol Authors: Ji Yeon Park (jybark990118@naver.com) Young-Woo Kim (gskim@ncc.re.kr) Keun Won Ryu (docryu@korea.com) Byung-Ho Nam (byunghonam@ncc.re.kr) Young Joon Lee (yjleegnu@gmail.com) Sang Ho Jeong (jshgnuh@naver.com) Ji-Ho Park (goodgsdr@gmail.com) Hoon Hur (hhcmc75@naver.com) Sang Uk Han (hansu@ajou.ac.kr) Jae Seok Min (mdoogy@hanmail.net) Ji Yeong An (jar319.an@samsung.com) Woo Jin Hyung (wjhyung@yuhs.ac) Gyu Seok Cho (gschogs@schmc.ac.kr) Gui Ae Jeong (gwsdlove@schmc.ac.kr) Oh Jeong (surgeonjeong@gmail.com) Young Kyu Park (parkyk@jnu.ac.kr) Mi Ran Jung (zuchum@naver.com) Hong Man Yoon (red10000@ncc.re.kr) Bang Wool Eom (kneeling@hanmail.net)

2 Version: 1 Date: 03 May 2016 Author s response to reviews: BCAN-D Assessment of laparoscopic stomach preserving surgery with sentinel basin dissection versus standard gastrectomy with lymphadenectomy in early gastric cancer-a multicenter randomized phase III clinical trial (SENORITA trial) protocol Ji Yeon Park, MD; Young-Woo Kim; Keun Won Ryu; Byung-Ho Nam; Young Joon Lee; Sang Ho Jeong; Ji-Ho Park; Hoon Hur; Sang Uk Han; Jae Seok Min; Ji Yeong An; Woo Jin Hyung; Gyu Seok Cho; Gui Ae Jeong; Oh Jeong; Young Kyu Park; Mi Ran Jung; Hong Man Yoon; Bang Wool Eom BMC Cancer Dear editors, First of all, thank you for considering our manuscript. To meet the editors comments, we have made some changes to the previously submitted manuscript. The final version of the revised manuscript is uploaded and replaced the original manuscript. Sincerely, Byung-Ho Nam

3 Department of Cancer Control and Policy, Graduate School of Cancer Science and Policy, National Cancer Center, 323 Ilsan-ro, Ilsandong-gu, Goyang-si Gyeonggi-do, 10408, Republic of Korea Editor's comments: 1. Ethical and Funding Approval Documentation Before we can proceed with your submission, can you please forward copies of all ethical approval and funding approval for our records. These documents should be sent as attachments to the following address, Please DO NOT upload these documents as additional files in the submission system. If your documents are not in English, please could you provide translated versions of the relevant parts. These should be endorsed and signed by a contactable person at the institution. Please also include the original documents. Can you please confirm in your cover letter that you have forwarded the requested documentation to BMCSeriesEditorial@biomedcentral.com. --> All the requested copies of ethical approval (original version as well as translated versions) were forward to the address described above. It is also confirmed in the cover letter. 2. Funding A study is considered to be externally funded if the authors have been awarded a grant for the study by a major funding body (e.g. governmental funding/ award from a charitable foundation). If a study has not received external funding, then the study protocol will be sent for peer-review with a member of our Editorial Board. If a study has received funding/assistance from a commercial organization, this should be clearly stated in the 'competing interests' section of your manuscript, and the study protocol will be sent for peer-review by a member of our Editorial Board. Can you please confirm whether your study protocol has undergone peer-review by the funding body.

4 --> Our study protocol is supported by the grant from National Cancer Center, Korea as intramural research program. This protocol has already undergone peer-review and approved by each participating institution. 3. Study status The protocol must be for a study that is ongoing. An ongoing study is defined as one where the investigators are still collecting, or analyzing data. Can you please confirm what stage your study is currently at. --> The trial is open for recruitment since March 2013 and currently recruiting. 4. Related Articles Can you please clarify whether any publications containing the results of this study have already been published or submitted to any journal. If so, can you please provide a list of the related articles. --> The results from the antecedent quality control study were published in the Medicine as follows: 1. Lee YJ, Jeong SH, Hur H, Han SU, Min JS, An JY, et al. Prospective Multicenter Feasibility Study of Laparoscopic Sentinel Basin Dissection for Organ Preserving Surgery in Gastric Cancer: Quality Control Study for Surgical Standardization Prior to Phase III Trial. Medicine. 2015;94(43):e1894. However, the results of this phase III trial have never published or submitted to any journal previously. 5. Please provide address details for all authors on the title page of the manuscript.

5 --> The address details for all authors are given on the title page of the revised manuscript. 6. Please include the trial registration date in the abstract with the trial number. --> The trial registration information including the registration date and trial number are described in the abstract. 7. Please include a full Declaration section at the end of the manuscript, which should include all the information as detailed in our Instructions for Authors (please see: --> A full declaration section is included at the end of the manuscript, which includes lists of abbreviation, competing interests, authors contribution, acknowledgements, and authors information.