CURRICULUM VITAE Ph.D., Biochemistry, University of Madras, Guindy Campus, Chennai
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1 CURRICULUM VITAE Dr. A. MADAN KUMAR Scientist C Molecular and Nanomedicine Research Unit, Centre for Nanoscience and Nanotechnology, Sathyabama University, Chennai madankumarbio@gmail.com madankumar@sathyabama.ac.in Ph: ; Educational Qualification Ph.D., Biochemistry, University of Madras, Guindy Campus, Chennai M.Sc., Medical Biochemistry, Dr.ALM Post Graduate Institute of Basic Medical sciences, University of Madras, Taramani Campus, Chennai B.Sc., Chemistry, Bharathiar University, Coimbatore Academic Honors & Position 2015 Awarded Young scientist by Department of Science and Technology (DST), Government of India, New Delhi 2015 Invited talk about Cancer: Nanotheranostics on National workshop on Nanoscience and Nanotechnology (NWNST-2015) January Bankura Unnayani Institute of Engineering, Bankura, Calcutta 2015 Oral presentation of Anti-inflammatory effect of Geraniol against 4NQO induced oral carcinogenesis in rats at Indo cancer summit 2015 Hyderabad, India Awarded Senior Research Fellowship sponsored by ICMR (Indian Council of Medical Research), Government of India, New Delhi 2012 Oral presentation entitled "Apoptotic effect of geraniol against 4- Nitroquinoline-1-oxide induced oral carcinogenesis in rats" in the National 1
2 conference on NC-HepCD-2012 at Pondicherry University, Puducherry, India till date working as Scientist C, at Molecular and Nanomedicine Research Unit, Sathyabama University, Chennai Research Experience Project entitled Screening and molecular characterization of Flk-1 inhibitor(s) from marine sponge symbionts and real time molecular imaging studies funded by Department of Science and technology (DST)- India Project entitled Studies on the anticancer mechanisms of PI3K inhibitor(s) from marine sponge symbionts funded by Department of Biotechnology, -India Research experience on project entitled Molecular mechanisms involved in the chemopreventive role of Geraniol against 4-Nitroquiniline-1- oxide induced Oral carcinogenesis in rats as a Research scholar at Department of Biochemistry, University of Madras, Chennai, India Under the guidance of Prof.T.Devaki, Department of Biochemistry, University of Madras, Chennai, India Research project experience on project entitled Magnetic Nanoparticles for effective target drug delivery of Carvacrol against Liver Carcinogenesis- A Molecular Approach as a Senior Research Fellow funded by ICMR in Department of Biochemistry, University of Madras, Chennai, India Research project experience on project entitled Antioxidant effect of Silymarin and Dichlorofenac against Carbon tetrachloride induced liver damage guided by Prof.Sakthisekaran, Department of Medical Biochemistry, Dr.ALM PG Institute of Basic Medical sciences, Taramani campus, university of madras, Chennai, India. List of Publications 1. Madankumar. A, Tamilarasi. S, Premkumar. T, Gopikrishnan M, Nagabhishek. N, Devaki T. 2
3 Geraniol attenuates 4nqo induced tongue carcinogenesis through downregulating the activation of NF-κB in rats. Mol Cell Biochem Oct 10;434(1-2):7-15. Doi.org/ /s S.N.Nagabhishek, A. Madankumar, T.Devaki. Anti-Inflammatory activity of geranial against 4NQO induced oral carcinogenesis in rats. J Cancer Sci Ther. 2015, 7:10 DOI: / C Antony V. Samrot, B. Suvedhaa, Chamarthy Sai Sahithya A. Madankumar. Purification and Utilization of Gum from Terminalia Catappa L. for Synthesis of Curcumin Loaded Nanoparticle and Its In Vitro Bioactivity Studies. Journal of Cluster Science Doi.org/ /s Madankumar A, Devaki T. Geraniol, a component of plant essential oils a review of its pharmacological activities. (2015). Int J Pharm Pharm Sci, ISSN: , Booupathy Lokeshkumar, Arumugam Madankumar, et al. Chemopreventive Effect of Myrtenal on developing 1, 2-Dimethyl Hydrazine- induced Aberrant Crypt Foci and Bacterial Enzymes Activity in Wistar Rats (2015). Journal of Food and Drug Analysis. 6. Booupathy Lokeshkumar, Arumugam Madankumar, et al. Anti-Oxidative Eff ect of Myrtenal in Prevention and Treatment of Colon Cancer Induced by 1, 2-Dimethyl Hydrazine (DMH) in Experimental Animals (2015). Biomol Ther 23(0), Madankumar A, Jayakumar S, Gokuladhas K, Rajan B, Raghunandhakumar S, Asokkumar S, Devaki T. Geraniol modulates tongue and hepatic phase I and phase II conjugation activities and may contribute directly to the chemopreventive activity against experimental oral carcinogenesis. Eur J Pharmacol Apr 5;705(1-3): doi: /j.ejphar Epub 2013 Mar 13. PubMed PMID: Madankumar A, Jayakumar S, Devaki T. Geraniol, a component of plant essential oils prevents experimental oral carcinogenesis by modulating glycoprotein abnormalities and membrane bound ATPase s. (2013) Int J Pharm Pharm Sci, Vol 5, Issue 1, Madankumar A, Jayakumar S, Asokkumar S, Raghunandhakumar S, Naveenkumar C, Devaki T. Chemopreventive potential of geraniol on 4-Nitroquinoline-1-oxide induced oral carcinogenesis in rats. Int J Res Pharm sci., 2(4), 2011, Jayakumar S, Madankumar A, Asokkumar S, Raghunandhakumar S, Gokula dhas K, Kamaraj S, Divya MG, Devaki T. Potential preventive effect of carvacrol against diethylnitrosamineinduced hepatocellular carcinoma in rats. Mol Cell Biochem. 2012; 360(1-2): doi: /s PMID:
4 11. Binuclara J, Asokkumar S, Naveenkumar C, Raghunandakumar S, Madankumar A, Rajitha R, Devaki T. Protective Efficacy of Diosmin Against Experimentally Induced Non-Alcoholic Steatohepatitis. Asian J. Exp. Biol. Sci Vol. 4(3): Balan Rajan, Shanmugam Sathish, Subramaniyan Jayakumar, Arumugam Madankumar, Krishnan Gokuladhas, Thandavamoorthy Premkumar, Ramasamy Elamaran, Mani Gopikrishnan, Thiruvengadam Devaki. Synthesis and in vitro anticancer evaluation of 2- isopropyl-5-methylphenol Loaded PLGA based iron oxide Nanoparticles Biomedicine & Preventive Nutrition, (2014) Vol 4, Issue 2, Pages Premkumar Thandavamoorthy, Rajan Balan, Jayakumar Subramaniyan, Madankumar Arumugam, Binuclara John, Gokuladhas Krishnan, Elamaran Ramasamy, Gopi Krishnan Mani, Ravikumar Rajendran, Devaki Thiruvengadam. Alleviative Role of Rutin Against 4- Nitroquinoline-1-Oxide (4-NQO) Provoked Oral Squamous Cell Carcinoma in Experimental Animal Model. Journal of Pharmacy Research 2014,8(7), Training and Scientific Meetings 1. Trained at National Workshop on Molecular epigenetic conducted by Department of Endocrinology, Dr.ALM PG IBMS, Taramani campus, university of madras, Chennai on 27th Nov Attended workshop on Recent Trends in the Diagnosis of Malignant Diseases held on 27th November 2010 conducted by Department of Biochemistry, Cancer Institute (WIA), Chennai, India. 3. Participated in National conference on "The Role of Free Radicals in Health and Diseases" held at 27th & 28th January 2012 conducted by Department of Biochemistry, University of Madras, Chennai, India. 4. Participated in International conference on "New Horizons in Cancer Research:Biology to Prevention to Therapy" held during 13th to 16th December 2011 organized by American Association of Cancer Research (AACR), Gurgaon, New Delhi (NCR), India. 5. Trained at workshop on "Animal Handling and Animal Ethics" held from 1 to 5th December 2011 conducted by Institutional Animal Ethical Committee, Centre for Advanced Studies in Botany, University of Madras, Chennai, India. 4
5 6. Participated in National conference on "Nanoscience and Nanotechnology- NCNN-2011" held during 25-27th August 2011 conducted by National Centre for Nanoscience and Nanotechnology, University of Madras, Chennai, India. 7. Participated in National Seminar on "Cellular and Molecular Neurobiology in Health and Diseases"- Neucell-2011 held on 11th & 12th February 2011 conducted by Department of Biochemistry, University of Madras, Chennai, India. 8. Participated in International conference on "Cancer Biology; Molecular Mechanisms and Novel Therapeutics" held during 18-20th February 2010 Organized by Department of Biotechnology, Indian Institute of Technology, Chennai, India. Lab members Cancer Biology lab 1. Dr. Jayakar Santhosh National Post doctoral Fellow, India. 2. S.N. Nagabhishek Senior Research Fellow DST, India 3. Mrs.Gayathri Karanam Senior Research Fellow DBT, India 4. Ms. Chinmayi sri amulya Research Scholar URF 5. Mrs. Priyanka Research Scholar (Part time PhD) 6. Samkeliso Takaidza NAM S& T International Fellow, India South Africa. 5
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