Cleaning And Disinfectant Products

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1 Cleaning And Disinfectant Products

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4 Cleaning: allows the physical removal of microorganisms allows prevents inactivation of the disinfectant by organic matter complete surface contact during further decontamination procedure Through cleaning of items is a prerequisite before disinfection and sterilization is commenced Disinfection: by heat or chemicals will destroy microorganism but not bacterial spores chemical disinfection does not necessarily kill all microorganisms present but reduces them to a level not harmful to health Antiseptics: the agents must have effective antimicrobial activity must not be toxic to living tissues chemicals used to kill microorganisms on skin or living tissue Sterilization: a process which achieves the complete destruction or removal of all microorganisms, including bacterial spores

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6 Level of disinfection Spores TB Vegetative bacteria Fungi Nonlipid & small viruses Lipid & mediumsize viruses Cold chemical sterilization High + * Inter-mediate - might most most some + Low - - +/- +/- +/- + * high-level disinfectants may not be able to kill large numbers of spores

7 Unlike sterilization, disinfection is not sporicidal. A few disinfectants will kill spores with prolonged exposure times (3 12 hours); these are called chemical sterilants. At similar concentrations but with shorter exposure periods (e.g., 20 minutes for 2% glutaraldehyde), these same disinfectants will kill all microorganisms except large numbers of bacterial spores; they are called high-level disinfectants. Low-level disinfectants can kill most vegetative bacteria, some fungi, and some viruses in a practical period of time (<10 minutes). Intermediate-level disinfectants might be cidal for mycobacteria, vegetative bacteria, most viruses, and most fungi but do not necessarily kill bacterial spores. Germicides differ markedly, primarily in their antimicrobial spectrum and rapidity of action.

8 Low risk area : Financial, Official Moderate risk areas : Hospital ordinarily wards High risk areas : ICU, NICU, Isolated rooms Very high risk areas : Operation rooms

9 Class of item Use of item Example Critical Semi-critical Non-critical Enter vascular system or sterile body tissues Comes in contact with intact mucous membranes Touches only intact skin Hypodermic needle, Scalpels and other surgical instruments, Biopsy forceps Vaginal spec., Anaesthetic equipment, flex. Endoscopes Blood pressure cuff, Baby weigh scale, Examining table top Decont. level needed Sterilization High-level disinfection (by heat or chemicals) Intermediatelevel or lowlevel disinfection

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12 Biofilms are microbial communities that are tightly attached to surfaces and cannot be easly removed Microbes within them can be resistant to disinfectants by multiple mechanisms, including physical characteristics of older biofilms, genotypic variation of the bacteria, microbial production of neutralizing enzymes, and physiologic gradients within the biofilm (e.g., ph) Bacteria within biofilms are up to 1,000 times more resistant to antimicrobials than are the same bacteria in suspension

13 They are present on numerous medical devices (e.g., contact lenses, pacemakers, hemodialysis systems, urinary catheters, central venous catheters, endoscopes) Enzymes and detergents can degrade biofilms or reduce numbers of viable bacteria within a biofilm.

14 Cleaning and disinfection of the environment Cleaning and disinfection of medical device Disinfection of the skin and mucous membrane

15 The Ideal Disinfectant Broadly active (killing pathogens) Not poisonous (or otherwise harmful) Penetrating (to pathogens) Resistant to inactviation Not damaging to non-livingmaterials Stable Easy to work with Otherwise not unpleasant

16 High Level Hydrogen Peroxide Peracetic acid Glutaraldehyde Formaldehyde Intermediate Level Chlorine Iodine Alcohols Low level Phenolics Quaternary Ammonium Compounds

17 Environmental surfaces

18 Strategies for cleaning and disinfecting surface Potential for direct patient contact Degree and frequency of hand contact Potential contamination of the surface with body substance or environmental sources of microorganism (soil, dust, or water)

19 Justification for Using a Disinfectant Surfaces may contribute to transmission of epidemiologically important microbes (e.g., VRE, MRSA, C. difficile) Needed for surfaces contaminated by blood and OPIM Disinfectants are more effective in reducing microbial load Detergents become contaminated and result in seeding the patients environment with bacteria CDC recommends disinfection of noncritical equipment and surfaces for patients on isolation precautions One product for decontamination of noncritical surfaces (that is, floors and equipment)

20 Pathogens implicated in transmission via contaminated noncritical surfaces Bacteria Acinetobacter, Pseudomonas, Clostridium difficile methicillin-resistant Staphylococcus aureus Vancomycin-resistant Enterococcus spp. Viruses SARS Rotavirus Respiratory syncytial virus (RSV)

21 Enterococcus Countertops: E. faecalis = 5 d, E. faecium = 7 d Bedrails = 24 hours Telephone handpieces = 60 minutes Stethoscopes = 30 minutes Gloved and ungloved fingers >60 minutes Noskin G, et al. ICHE 1995;16:

22 deconex 50AF Aldehyde free surface disinfectant For disinfection and cleaning of floors, walls and medical devices Quat + Amine + Guanidine 0.5-2% in 5-30 min 1 day in use DGHM approved Before using for the first time, prior cleaning with deconex 36 INTENSIV is recommended.

23 VAH Approved deconex SURFACE AF For disinfection and cleaning of floors, walls and medical devices Newly formulated according to latest demands. Non contaminated use solution can be stored for Ecofriendly Economical 14 days. Contact time 5min 15min Concentration In use 1% 0.5% Before using for first time, prior cleaning with Deconex 36 INTENSIVE is recommended

24 deconex SOLARSEPT VAH Approved Ready to use, alcoholic disinfectant with rapid effect For spray- and/or wipe disinfection of small surfacesincluding such of medical devices Contact time 30 s 30 s ضد ويروس HIV,HBV ضد باکتری قارچ و باسيل سل Efficacy

25 Medical instruments

26 deconex 53 PLUS Aldehyde-free, non-fixing disinfectant for instruments Quat + Guanidine 14 days in use 30 days out of use Contact time 15min 30min 60min Concentration In use 2% 1.5% 1% A visibly contaminated solution must be replaced with a fresh solution. Before using for the first time, prior cleaning with deconex 36INTENSIV is recommended.

27 deconex 53 INSTRUMENT Aldehyde-free, non-fixing disinfectant for instruments VAH Approved For manual disinfection and cleaning of surgical instruments, care utensils and dental instruments. High efficacy at low concentrations Ultrasonic bathquat + Guanidine 14 days in use 30 days out of use Contact time 5min 15min Concentration In use 2% 0.5% A visibly contaminated solution must be replaced with a fresh solution. Before using for the first time, prior cleaning with deconex 36 INTENSIV is recommended.

28 deconex 54 SPORCIDE For sporicidal disinfection of all medical instruments and utensils, including flexible endoscopes Ready-to-use, based on glutaraldehyde Dosage/exposure time For bactericidal, tuberculocidal, fungicidal and virucidal effect 10 min For sporicidal effect 60 min Thoroughly clean the instrument Before using Deconex 54 SPORCIDE 35 days in use solution

29 deconex HLD PA / PA20 For high-level disinfection of all medical instruments and utensils, including flexible endoscopes Based on peracetic acid decode HLD PA activated with deconex PA20 is a : ready-to use, high-level disinfectant In use solution : more than 14 days deconex TEST-PA specifically developed for use with deconex HLD PA. Dosage/exposure time For bactericidal, tuberculocidal, fungicidal and virucidal (HIV, HBV)effect For sporicidal effect 5min 5min

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32 Alcohol hand rubs

33 Quat + Alcohol 30 sec for hygienic disinfection sec for Surgical disinfection HA without scent and dye decosept decosept HA VAH Approved Rub-in hand disinfectant For hygienic and surgical hand disinfection

34 COMPETITORS INFORMATION COMPARISON TABLE

35 PARTICULES SIZE METHODS LIMITS 15 µ 100µ Pulverization The particles are too heavy. The particles drop too quickly then product does not sufficiently disinfect top surfaces. It has not enough time to threat all surfaces (including those unreachable or hidden). 5 µ 15µ Fogging (Sterinis : 8 to 12µ) An ideal size of the particles. The disinfectant does not accumulate quickly. It has time to reach all surfaces and then to efficiently threat. 1 5µ Nebulization The particles tend to quickly vaporize. Then the disinfectant does not have enough time to threat effectively µ Gas vaporization

36 What is the Dry Mist Technology? Mist Technology TM A UNIQUE AND PATENTED TECHNOLOGY An aerospray system that produces an aerosol-quality mist with droplets between 8µ and 12µ (Gauss average)

37 Sterinis A device using a new technology of diffusion based on Dry Mist Technology TM Sterusil A powerful disinfectant product combining two efficient active substances (H Ag + )

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39 Door has to be closed Place Sterinis in an angle of the room. Windows have to be closed

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41 Automatic washer-disinfector Concentrated solutions 1. deconex 28 ALKAONE 2. deconex 26 PLUS 3. deconex 64 NEUTRADRY 4. deconex 41STS 5. deconex 41CLEAR 6. deconex TWIN BASIC/TWIN ZYME 7. deconex ENDOMATIC 8. deconex 25 ORGANACID

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44 7 bar operating pressure constant availability of steam, no pressure losses high heating power, constant pressure level perfect quality in "2-chamber design" environment-friendly without any chemicals with fixed nozzle or flexible hand piece, connection for compressed air optional

45 The new Elmasonic S units are available in 16 different sizes ranging from 0,5 litres to 90 litres cleaning tank made of cavitation-resistant stainless steel LED degas function 30 up to 80 C

46 electronic time and temperature control High-performance transducer systems run dry safe heating quick degassing (Degas/Autodegas) electronic sound field oscillation (Sweep) Tank capacity: 6,9 l

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