EE3080 Design and Innovation Project. Programme: Electromedical Technologies. Coordinator: Assoc. Prof. Justin Dauwels

Transcription

1 EE3080 Design and Innovation Project Programme: Electromedical Technologies Coordinator: Assoc. Prof. Justin Dauwels School of Electrical and Electronic Engineering Nanyang Technological University

2 What is Biomedical Engineering? Biomedical engineering is a multiple discipline and high technology area. It is to provide solutions for health care industries and services. ELECTROMEDICAL technologies: electrical engineering applied to healthca

3 Electrical Engineers Play a Key Role in Health Care Industries

4 Electrical Engineers Play an Key Role in Health Care Industries and Services Circuits and electronics Measurement and instrumentation Pacemaker

5 Electrical Engineers Play an Key Role in Health Care Industries and Services Information and signal processing ECG Brain Mapping from EEG Medical imaging and image processing

6 Electrical Engineers Play an Key Role in Health Care Industries and Services Modelling and control Telemedicine

7 Biomedical Engineering is Exciting It is important: Health Caring and Life Saving It is profound and challenging: Nobel Prizes in Medicine in 1979, for the development of Computed Tomography (CT) and in 2003 for the development of Magnetic Resonance Imaging (MRI). It is High Tech =

8 Health Care Industry is Robust and Resilient in the Economic Crisis Performance of Different Sectors of NYSE ( ) 1.8 x 104 health care sector energy sector financial sector

9 Where do Biomedical Engineers work? Research Institutions Hospitals Institute of Bioengineering and Nanotechnology Bioinformatics Institute Institute of Molecular and Cell Biology Defence Medical Research Institute Bioprocessing Technology Centre Laboratories for Information Technology Johns Hopkins Singapore Pte Ltd SGH NUH NCC SNEC NHC NNI SINGAPORE Companies Academic Institutions/ Government Boards NTU Universities Polytechnics Baxter Becton Dickinson Siemens Medical Instruments Medtronic GE Medical Boston Scientific GlaxoSmithKline MDS Analytical Technologies Perkin Elmer

10 Research at School of EEE on Electromedical Technologies microfluidic channel Micromanipulator & optical fiber fluidic inlets Opto- & Nano- Fluidic Chips Lab-on-Chip nanochannel microchannel Optical fiber Micromanipulator Integrated waveguides Integrated waveguides fluidic outlet Monolithic PDMS optofluidic chip Spectroscopyon-Chip Microscope-on- Chip POC Sensor Platform Wearable Respiratory Monitoring Inspired by Clinical Needs Reputed for Impactful Research Wireless Sensing Elderly Home Monitoring Quantum Dots Probe Photo-Thermal Imaging DCE Imaging Brain Disorder Diagnostic Neuro-Device Implants Telemedicine 25 Active EEE Faculty Members

11 Distributed Diagnosis & Home Healthcare (D2H2) Non-Contact Vital Sign Biosensors Tele-Rehabilitation Wherever the patient is.. Intelligent Controller Home Healthcare Monitoring or Diagnostic System Wearable System Smart Homecare Monitoring Handheld Devices Internet Clinics and Hospitals Personal Health Information Management System (PHIMS) Other Specialist & Clinicians Primary Care Provider Emergency Room Prof. Tjin Swee Chuan, et al

12 Bio-Imaging & Signal Processing DCE Imaging of Tumor Microcirculation Diagnosis/Treatment of Brain Disorders Nasopharyngeal Cancer Diagnosis with optical Coherence tomography Collimating lenses Ti:Sapphire Laser Mirror 2x2 fiber coupler Reference Arm Spectrometer White light Probe Arm The use of dynamic contrast-enhanced MR imaging (DCE MRI) and dynamic contrastenhanced CT imaging (DCE CT) as a biomarker for anti-angiogenesis therapy Neuro-electric Engineering for Curing Brain Disorders Nasopharyngeal Cancer Diagnosis with Optical Coherence Tomography Fluorescence Life-time Imaging for Medical Diagnosis of Cancerous Tissue Development of Photo thermal Imaging system for imaging sub-cellular organelles Processing and Classification of Heart Rate Variability Signals

13 Bio-Nano Technology and Devices Micro-fluidic Chips and Devices Lab on Chip (Nano-Droplet & Bubble Formation) Outlet Inlet Outlet nanochannel Formation of hydrogel plug Outlet Inlet nanochannel microchannel microchannel Transformation from plug to spherical droplet Microscope on Chip (3D Ultrasound, CMOS Imager) Point-of-Care Biosensor Platform + Optofluidic channels CMOS Imager Nanopattern fabrication Integrated LSPR Chip LSPR simulation Multilayer micro-fluidic chip (to form single tumor spheroid), device (for neuron culture) Lab on Chip (Nano-Droplet and bubble formation) to mimic blood flow in artery On-chip total internal reflection (TIR) microscope Point-of-Care Biosensor platform for screening/diagnosis of cancer & infectious diseases Microscope on Chip: 3D ultrasound system, CMOS imager near-field System

14 Major Laboratory Facilities Cell Culture Room Research inverted microscope, Incubator, Centrifuge, Water bath, Ultrapure water system, Ultralow (-80o) freezer, Cryogenic tank Biochemical Room Chemical cabinet, Chemical benches, Chemical hood, Universal laser cutting system Dark Room Optical tables, Lasers, Supercontinuum light source Other Equipments Ultrasound X-Y-Z scanning system, Sonix RP ultrasound system, Medelec Profile EEG system, Biopac, NORAXON EMG system, Desktop MRI scanning system.

15 Thanks! Join this programme to become a leader in healthcare innovation and improve the quality of life of many patients! We welcome your ideas! Professors will soon upload projects.

16 EE3080 Design and Innovation Project Programme: Electromedical Technologies Coordinator: Assoc. Prof. Justin Dauwels School of Electrical and Electronic Engineering Nanyang Technological University

17 What do we offer in Biomedical Electronics Option? Design Modules: EE4901 Biomedical Control System Design EE4902 Design of Medical Information Processing Systems Elective Subjects: EE4903 Physiological Systems Analysis EE4904 Biomedical Instrumentation EE4266 Process Control Systems EE4840 Biophotonics EE4266 Computer Vision Assoc. Prof. Justin Dauwels

18 School of Electrical and Electronic Engineering ELECTROMEDICAL TECHNOLOGIES Programme Coordinator: Prof Justin Dauwels Summary Electrical engineers have large impact in a diverse range of domains. One of these domains is healthcare. Did you know that the fully implantable pacemaker was invented by an electrical engineer named Earl Bakken? Later he founded Medtronic, currently world's fourth largest medical device company. Nowadays, medical devices such as neural implants, MRI and CT scanners, defibrillators, and prostheses, contain highly sophisticated electronic circuits and execute powerful signal processing and control algorithms. Electrical engineering has played a key role in medicine and healthcare, and is expected to become even more instrumental as medical devices become increasingly complex. The electrical engineers of the future will be in an ideal position to make exciting advances in healthcare treatment, including diagnosis, monitoring, and therapy. Figure 1: Brain-controlled prosthetic arm The projects under the theme of Electromedical technologies are quite diverse, but are all centered around electrical engineering technologies applied to medicine and biology. Some projects are software oriented, whereas others have a focus on hardware development. Potential topics include (but are not limited to) design of biomedical circuits and systems, smart biomedical signal processing algorithms, neuromorphic circuits, analysis of MRI, CT, PET images, brain-computer interfaces (see Fig.1), design of microfluidic devices, lab-on-a-chip, wearable medical systems, smart space for healthcare services, functional imaging, and point-of-care clinical screening and medical diagnostics. In other words, you can easily find a role to play to suit your interest in the projects! Crash courses Depending on the needs of the students, this DIP program will offer practical hands-on courses by experienced developers on Matlab programming, biomedical signal and image processing, and hardware development. Garage@EEE Teams in this programme who wish to further develop their technology and pursue commercialization can apply for support from the Garage@EEE. Support and advice will be provided by the DIP teams and their supervisors who went through this process in the past.