Chapters 15,16,17. Mandy Leber RVT, RLATG Training and Outreach Coordinator

Transcription

1 Chapters 15,16,17 Mandy Leber RVT, RLATG Training and Outreach Coordinator

2 17.9 In relation to rodents, what does genetic engineering mean? a. Genes are specified in an engineered design. b. Rodents were cross-bred and then inbred to create special strains. c. Genes were manipulated in the laboratory and transferred into an animal. d. Engineered genes were removed from a mouse and cultured in the laboratory.

3 15.11 kilogram equals how many grams? a. 10 b. 100 c d. 10,000

4 16.6 In a research experiment testing a new drug, which group of animals receives the test substance? a. The experimental group b. The control group c. The baseline group d. The sentinel group

5 15.1 The prefix hemi means: a. powerful b. large c. fast d. half

6 15.23 Which of the following would be the most acidic? a. A solution with a ph of 1 b. A solution with a ph of 6 c. A solution with a ph of 9 d. A solution with a ph of 13

7 16.11 Which of the following best describes the experimental design of a study? a. The detailed description of how the animals will be euthanized and how their carcasses will be disposed of b. A step by step protocol describing how animals will be used in the study, including all procedures, drugs, and manipulations done to the animals c. The written narrative describing the justification to use live animals in research d. A plan that describes the methods used to answer the research question or hypothesis

8 17.1 What is the scientific study of heredity called? a. Transgenesis b. Genetic engineering c. Genetics d. Traits

9 16.5 Planned or controlled manipulations within a research study are called: a. non-experimental variables. b. experimental variables. c. designed change factors. d. non-designed change factors.

10 17.10 What is the period of time between fertilization and birth called? a. Conception b. Gestation c. Parturition d. Kindling

11 17.2 A permanent change in an inherited or genetic factor is called a: a. persistent trait. b. transferred characteristic. c. rotation. d. mutation.

12 15.5 The root words pulmo and pneumo refer to which part of the body? a. Larynx b. Lungs c. Stomach d. Liver

13 16.9 Which of the following is an example of basic research? a. Testing the safety of a new antibiotic ointment b. Testing a new drug therapy for Parkinson's disease c. Using cows for developing a new vaccine for chicken pox d. Studying the normal brain function of rats

14 17.3 What do genes consist of? a. DNA in the chromosome b. DNA in the ribosome c. RNA in the chromosome d. RNA in the ribosome

15 16.3 Although the IACUC must approve all new studies before they can begin, researchers may add new experimental groups or procedures during the study without IACUC approval. a. True b. False

16 15.4 What does the word hypertension mean? a. High blood pressure b. Low blood pressure c. High stress d. Low stress

17 16.8 Which of the following is a non-experimental variable that could interfere with research results? a. Genetic manipulation b. Changing cages on time every week c. Mistake in recording data d. Injection of test substance

18 17.4 What do chromosomes consist of? a. Proteins and fat tissue b. RNA and organelles c. Amino acids d. DNA and proteins

19 15.2 What part of a word provides the essential core of its meaning? a. The prefix b. The suffix c. The root d. The participle

20 16.1 When is the hypothesis developed during a research study? a. At the very beginning, when planning the study b. At the very end, when writing up the results c. After the animal use protocol is approved by the IACUC d. After ordering the animals

21 17.17 Which species are brought together only for mating and separated immediately after mating takes place? a. Rats and dogs b. Hamsters and rabbits c. Cats and ferrets d. Guinea pigs and nonhuman primates

22 15.3 The metric system is based on powers of: a. 10 b. 100 c. 10,000 d. 1000

23 17.5 What is the term for an animal s observable characteristics, including its physical appearance and internal physiology? a. Genotype b. Phenotype c. Karyotype d. Histiotype

24 15.15 Normal body temperature for a dog, degrees F, is what temperature Celsius? a b c d. 36.0

25 16.2 In most facilities, no research experiments on live vertebrate animals may begin before the experiments are approved by: a. the USDA. b. OLAW. c. the IACUC. d. the FDA.

26 17.6 What is it called when an animal contains altered DNA designed to turn off a specific gene? a. Punchout b. Knockin c. Knockout d. Recessive

27 15.6 What does the abbreviation mg stand for? a. Microgram b. Multigram c. Milligram d. Macrogram

28 16.4 In a research experiment, what is the term to describe the group of animals that does not receive the experimental treatment? a. The sentinel animals b. The baseline animals c. The control animals d. The experimental animals

29 15.7 If an animal has an impairment in part of the immune system, it is referred to as being: a. immunoabnormal b. immunodeficient c. pathodeficient d. nonfunctional.

30 15.16 What element does the symbol K stand for? a. Krypton b. Potassium c. Chlorine d. Sodium

31 16.7 If an animal has an impairment in part of the immune system, it is referred to as being: a. immunoabnormal b. immunodeficient c. pathodeficient d. nonfunctional.

32 15.7 What does the abbreviation kg stand for? a. Keppler grain b. Kelvin grain c. Kilogram d. Kardiogram

33 16.10 In a research study, what is a variable? a. Factors or conditions that can change the results or outcome of a study b. The part of the protocol that specifies the animal use c. The group of animals that receives the experimental treatment d. The type of approval given by the IACUC

34 17.8 Which of the following is NOT a standard method to check for pregnancy in rodents? a. Weight monitoring b. Urine dip stick test c. Taking a radiograph (x-ray) d. Gentle palpation

35 In the metric system, the prefix kilo (k) means: a. one hundredth. b. one hundred. c. one thousandth. d. one thousand.

36 17.22 Which of the following describes a harem mating system? a. One male is housed with two or more females, and the females are removed as they become pregnant. b. One female is housed with two or more males, and the males are removed when the female becomes pregnant. c. One male is housed with two or more females and the group is kept together after mating. d. One female is housed with two males, and the group is kept together after mating.

37 15.20 You need to make a 1:3 dilution of chemical X. Your final volume is 600 ml. What is the volume of chemical X you will use? a. 100 ml b. 200 ml c. 300 ml d. 400 ml

38 17.11 Mucous plugs may remain in a female rodent s vagina for up to how long after mating? a. 24 hours b. 6 hours c. 48 hours d. 12 hours

39 ml equals how many L? a. 1/1000 b. 1/10 c. 10 d. 1000

40 17.15 Which of the following is TRUE about inbred strains of mice? a. Pups may need extra time with their mothers before weaning. b. They tend to be more vigorous and better breeders. c. They are usually white in color. d. They rarely cannibalize their young.

41 degrees Fahrenheit is equal to degrees Celsius. a b c d. 23.9

42 17.19 Which breeding scheme results in the largest number of offspring from the least number of breeding animals? a. Monogamous mating b. Inbred mating c. Polygamous mating d. Outbred mating

43 15.14 A kilogram is approximately equal to how many pounds? a. 1.1 b. 3.3 c. 2.2 d. 4.4

44 17.21 What would be a good husbandry practice with rodent dams or rabbit does with a first litter? a. Clean the cage on a daily basis. b. Move the newborn animals to a clean spot in the cage. c. Handle the newborns as often as possible to get them used to human contact. d. Delay cage changes and other husbandry tasks for a few days.

45 15.8 What is the standard unit of weight in the metric system? a. Gram b. Meter c. Kilogram d. Celsius

46 17.13 What breeding method produces the maximum amount of genetic differences between animals from the same colony? a. Outbreeding b. Inbreeding c. Nearbreeding d. Line breeding

47 degrees Celsius is equal to degrees Fahrenheit. a b c d. 98.6

48 17.16 Under which mating system is it difficult to determine which dam gave birth to specific pups? a. Harem mating b. Hand mating c. Monogamous mating d. Cross breeding

49 15.9 What is the standard unit of length in the metric system? a. Gram b. Meter c. Liter d. Celsius

50 17.18 When breeding mice, breeding records are nice to have but not essential. a. True b. False

51 15.13 About how many centimeters are in an inch? a b. 2.5 c. 25 d. 5

52 What type of animals result when there have been at least 20 generations of brother and sister matings? a. Outbred strain b. Outbred stock c. Inbred stock d. Inbred strain

53 15.26 To make a total volume of 1 L at 1:4 dilution of a cleaning product, how much diluent should be added to the cleaning product? a. 250 ml b. 500 ml c. 1 L d. 750 ml

54 17.20 What is dystocia? a. Difficult birth b. Protrusion of vaginal tissue c. Cannibalism d. Scruffing

55 15.25 What term refers to a liquid used to dilute another substance? a. Rehydrant b. Diluent c. Insolvent d. Solvent

56 17.12 What breeding method produces animals with minimal genetic variation? a. Outbreeding b. Inbreeding c. Crossbreeding d. Nearbreeding

57 15.24 Which of the following would be the most alkaline? a. A solution with a ph of 1 b. A solution with a ph of 5 c. A solution with a ph of 9 d. A solution with a ph of 13

58 15.21 NaCl is the chemical formula for a. soap. b. water. c. baking soda. d. table salt.

59 15.22 The act of shivering or sweating in order to maintain body temperature is an example of: a. hyperstasis. b. heterostasis. c. homeostasis. d. hypophagia.